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15921
The potential of stem cell therapy in Multiple Sclerosis treatment: a review
Published 2023-12-01“…Most current clinical trials continue to focus on establishing the safety and efficacy of adipose derived stem cell-based therapeutics, with promising results becoming progressively evident. This review reports stem cell-based therapies as potential therapeutic approaches in the treatment and management of Multiple Sclerosis. …”
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15922
Informing the development of diagnostic criteria for differential diagnosis of alcohol-related cognitive impairment (ARCI) among heavy drinkers: A systematic scoping review.
Published 2023-01-01“…These studies revealed a lack of coordinated research and progress towards the development and standardisation of diagnostic criteria for ARCI. …”
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15923
Impact of Comorbidities on the Severity of Disease & Outcome in Children with COVID 19 at a Tertiary Care Pediatric Hospital, Rawalpindi.
Published 2023-06-01“…It is considered that COVID-19, in those with underlying health conditions or co-morbidities, has an increasingly rapid and severe progression, often leading to death. This study is designed to evaluate the impact of co-morbidities on the severity and outcome of COVID-19 infection in children. …”
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15924
Early referral to nephrological care improves long-term survival and hospitalization after dialysis initiation, independent of optimal dialysis start – a call for harmonization of...
Published 2024-12-01“…Early treatment of kidney disease can slow disease progression and reduce the increased risk of mortality associated with end-stage kidney disease. …”
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15925
Deep Learning and Radiomics in Triple-Negative Breast Cancer: Predicting Long-Term Prognosis and Clinical Outcomes
Published 2025-01-01“…This article reviews recent progress in the application of deep learning, ultrasound, MRI, and radiomics for TNBC diagnosis and treatment, based on research from both domestic and international scholars.Keywords: deep learning, MRI, radiomics, triple negative breast cancer, ultrasound…”
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15926
Interferon (IFN)-gamma (γ) inducible protein 10 (IP-10) in the diagnosis of latent and active tuberculosis in Bacille Calmette Guerin (BCG)-vaccinated pediatric population.
Published 2025-01-01“…Furthermore, detecting cases of latent Mycobacterium tuberculosis (M.tb) infection (LTBI) that have a high risk of progressing to active TB disease remains a significant diagnostic hurdle.…”
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15927
Influence of Dry Beach on the Dynamic Stability of Ash Storage Field: A Numerical Analysis
Published 2021-01-01“…As the length of the dry beach increases, the maximum horizontal displacements show a certain decrease, but they occur progressively further away from the third subdam, so that, under dynamic action, the dams become safer. …”
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15928
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15929
Sustainable Distance E-Learning for Enhanced Students Retention and Support: Faculty of Law National Open University of Nigeria in Focus
Published 2016-07-01“…Despite the monumental progress made by NOUN, there are challenges related to students’ retention and support militating against realization of the objectives of establishing the university. …”
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15930
Integrative Bioinformatics Analysis Unravel the Association between Intracerebral Hemorrhage and Cellular Apoptosis through Immune Infiltration
Published 2024-01-01“…Through bioinformatics analysis, we identified PPP1R15A, IL1R1, and TYROBP as crucial genes in the occurrence and progression of ICH, with the potential involvement of Activated dendritic cells and CD56dim natural killer cells in these processes.…”
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15931
Phytochemistry and pharmacological advances of Ascophyllum nodosum in the management of human diseases: A comprehensive review
Published 2025-02-01“…Results: We conducted a comprehensive review of the research progress on ANE, focusing on its pharmacological effects on various diseases using animal models, mechanisms of action, and composition, are as not explored in preceding reviews. …”
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15932
PROMETHEUS: Long-Term Exacerbation and Mortality Benefits of Implementing Single-Inhaler Triple Therapy in the US COPD Population
Published 2023-01-01“…The US COPD population was modeled with 1000 simulations of patient progression over 10 years. Agent characteristics were based on literature and claims analysis of the 2016-2018 Medicare 100% fee-for-service and IBM MarketScan^®^ databases. …”
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15933
Linguistic means of creating an image of a person with intellectual disabilities in D. Keyes’s novel «Flowers for Algernon»
Published 2024-06-01“…But interfering with the character’s brain gives only a temporary improvement –– rapid progress is replaced by degradation. The changes in Charlie Gordon’s intellectual development are shown through his speech portrait –– an important means of revealing the image of the character and his inner world. …”
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15934
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15935
Assessment of fluoride bio-accessibility in early childhood diets
Published 2025-02-01“…However, the lack of data on fluoride bioavailability/bio-accessibility has hindered progress so far. This study aimed to measure fluoride bio-accessibility of the dietary sources commonly consumed by children below four years of age.MethodsA total of 103 food and meal samples were purchased, prepared, and analyzed for fluoride content, subjected to a standardized static in vitro digestion procedure and subsequent determination of fluoride concentration of resultant mixtures necessary for the final fluoride bio-accessibility calculation. …”
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15936
Fatty acid metabolism-related signature suggests an oncogenic role of TEKT1 in endometrial cancer
Published 2025-01-01“…Objective: The study aims to construct a prognostic signature to detect the molecular interaction between the fatty acid metabolism and the progression of endometrial cancer. Materials and methods: A total of 309 fatty acid metabolism relative genes were analyzed in the endometrial cancer cohort from The Cancer Genome Atlas. …”
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15937
Administration of a Next-Generation Probiotic Escherichia coli Nissle 1917-GLP-1 Alleviates Diabetes in Mice With Type 1 and Type 2 Diabetes
Published 2025-01-01“…Diabetes mellitus (DM) is a persistent and steadily progressing metabolic condition distinguished by unregulated high levels of blood glucose. …”
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15938
To study the role of tofacitinib and betamethasone pulse in the treatment of vitiligo at a tertiary care centre: an observational comparative study
Published 2024-01-01“…The new oral biologic tofacitinib, which is a Janus kinase inhibitor, is a new addition to the armamentarium of immunosuppressive therapy to halt disease progression in vitiligo. Tofacitinib is also known to inhibit IFN-γ mediated inflammation, which is an important step in the development of vitiligo lesions. …”
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15939
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15940
Efficiency of the Stool-PCR Test Targeting NADH Dehydrogenase (Nad) Subunits for Detection of Opisthorchis viverrini Eggs
Published 2021-01-01“…The early diagnosis of O. viverrini infection may interrupt the progression of the opisthorchiasis and other related illnesses, especially CCA. …”
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