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15901
Matching plus regression adjustment for the estimation of the average treatment effect on survival outcomes: a case study with mosunetuzumab in relapsed/refractory follicular lymph...
Published 2025-02-01“…Endpoints included overall survival (OS) and progression-free survival (PFS). Sensitivity analyses were performed to test robustness to different distributional assumptions (log-normal, log-logistic and exponential) or model specifications (second, third and fourth lowest AIC) for event times. …”
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15903
Effects of Delayed Metamorphosis on Larval Survival, Metamorphosis, and Juvenile Performance of Four Closely Related Species of Tropical Sea Urchins (Genus Echinometra)
Published 2014-01-01“…Juveniles from larvae of all four species that metamorphosed soon after becoming competent tended to have higher growth rates (test diameter and length of spines) than juveniles from larvae that metamorphosed after a prolonged period of competence with progressively slower growth the longer the prolonged period. …”
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15908
Hybrid Quality-Based Recommender Systems: A Systematic Literature Review
Published 2025-01-01“…This study aims to assess the progress achieved in the field of hybrid recommender systems to identify frequently used recommender approaches, explore the technical context, highlight gaps in the existing research, and position our future research in relation to the current studies.…”
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15909
Reasons for disengagement in first-episode psychosis – perspectives from service users and their caregivers
Published 2024-11-01“…A total of five categories each with subthemes were identified from the reasons for service user disengagement – individual factors, stigma, progression, treatment factors, and external factors. …”
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15911
Comorbidity in in patients with relapsing-remitting multiple sclerosis
Published 2024-10-01“…Comorbidity in multiple sclerosis is an urgent problem of modern neurology, since it can influence such factors as the time of diagnosis, the rate of disease progression and the rate of patient disability, the number of exacerbations and the patient’s quality of life. …”
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15912
Extracellular domain of TREM2 possess two distinct ligand recognition sites: Insights from machine-learning guided docking and all-atoms molecular dynamics simulations
Published 2025-01-01“…R47H and R62H in TREM2 may affect the development and progression of AD. Our knowledge-based and machine-learning guided docking and physics-based simulations study unveils deep insights into the endogenous ligand recognition by the positive surface ligand binding site and distant core site pave the way for exploration of other small molecules towards development of novel therapeutics against Alzheimer's disease.…”
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15913
Correlation of Platelet Indices with Severity of Gastroesophageal Varices in Patients of Liver Cirrhosis: A Research Protocol
Published 2025-02-01“…While various parameters have been explored to predict the progression and severity of these varices, platelet indices have not been extensively studied in cirrhosis patients with gastroesophageal varices in India. …”
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15914
One-year Prevalence, Comorbidities, and Cost of Hospitalizations for Alpha-1 Antitrypsin Deficiency among Patients with Chronic Obstructive Pulmonary Disease in the United States
Published 2017-07-01“…Future research should assess other differences between AATD and the general COPD population such as natural history of disease, treatment responsiveness and disease progression.…”
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15915
Weighted Gene Coexpression Network Analysis Identifies TBC1D10C as a New Prognostic Biomarker for Breast Cancer
Published 2022-01-01“…We downloaded raw data from several databases including TCGA and MDACC to identify TME hub genes associated with overall survival (OS) and the progression-free interval (PFI) by WGCNA. Correlations between hub genes and either tumor-infiltrating immune cells or immune checkpoints were conducted by ssGSEA. …”
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15916
Geospatial visualization and seasonal variation of heavy metals in river sediments
Published 2023-04-01“…Industrialization and agricultural developments are progressively causing ecological concerns, which must be addressed. …”
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The Value of Immune-Related Genes Signature in Osteosarcoma Based on Weighted Gene Co-expression Network Analysis
Published 2021-01-01“…This study is aimed at obtaining immune-related genes (IRGs) associated with the progression and prognosis of OS. Method. Expression profiling data and clinical data for OS were downloaded from the Therapeutically Applicable Research to Generate Effective Treatments (TARGET) database. …”
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15918
Therapeutic Potential of <i>Lappula patula</i> Extracts on Germline Development and DNA Damage Responses in <i>C. elegans</i>
Published 2025-01-01“…Results: Exposure to <i>L. patula</i> extracts resulted in a dose-dependent reduction in worm survival and larval developmental progress, with no significant impact on the male incidence. …”
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Efficacy and safety of new protease inhibitor faldaprevir in treatment of hepatitis C
Published 2013-12-01“…To discuss potentials of application of new NS3/NS4 protease inhibitor faldaprevir at chronic hepatitis C with genotype 1 HCV, including patients without response to previous antiviral therapy, liver cirrhosis, and to estimate its antiviral activity in the range of treatment modes without interferon.Key points. Significant progress was achieved in development of new modes of antiviral treatment of patients with the 1st HCV genotype due to introduction of the third agent possessing direct antiviral action. …”
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15920
Molecular and serological investigation of hepatitis B virus in patients with acute undifferentiated febrile illness at Tha Song Yang hospital, Tak Province, Thailand
Published 2025-01-01“…Abstract Background Hepatitis B virus (HBV) infection is associated with hepatitis, often progressing to liver cirrhosis or cancer, posing a significant public health challenge, particularly in Thailand. …”
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