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15861
STEP 1: The Scottish Trauma & Orthopaedics Equality Project: demographics and working patterns of a national workforce
Published 2025-01-01“…This study suggests that T&O in Scotland is an evolving speciality in terms of equality and diversity, and is making positive progress. Cite this article: Bone Jt Open 2025;6(1):103–108.…”
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15862
New Development Bank as Aid Donor to School Education
Published 2024-12-01“…Subsequent developments, including heightened attention to BRICS educational cooperation at high-level and ministerial meetings, the adverse impact of COVID-19 on global educational progress, and the appointment of Dilma Rousseff as NDB President, further solidified social infrastructure (including education) as a priority on the Bank’s strategic agenda. …”
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15863
Mapping C. difficile TcdB interactions with host cell-surface and intracellular factors using proximity-dependent biotinylation labeling
Published 2025-02-01“…To reach their intracellular targets, these toxins possess functional domains or subdomains that interact with and exploit various host factors and biological processes. Despite great progress in identifying many of the key host factors involved in the uptake of toxins, significant knowledge gaps remain as to how partially characterized and newly discovered microbial toxins exploit host factors or processes to intoxicate target cells. …”
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15864
Aqueous Extract of Leaves and Flowers of Acmella caulirhiza Reduces the Proliferation of Cancer Cells by Underexpressing Some Genes and Activating Caspase-3
Published 2024-01-01“…AE-Ac showed inhibitory effects on the expression of genes involved in cancer progression making it a potential health intervention agent that can be exploited in cancer therapy protocols.…”
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15865
Research on Damage Assessment of Buried Standard and Carbon-Fibre-Reinforced Polymer Petroleum Pipeline Subjected to Shallow Buried Blast Loading in Soil
Published 2021-01-01“…Buried petroleum pipelines may encounter threats from blast loading due to terrorist attacks, accidental explosions, and artificial blasting during in-progress construction. Carbon-fibre-reinforced polymer (CFRP) is often used for the repair and reinforcement of buried petroleum pipelines. …”
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15866
Mature Teratoma Combined with Bladder Stones: A Case Report and Literature Review
Published 2025-01-01“…She was then symptom-free and further follow-up observation was in progress. We also include a literature review concerning primary bladder teratoma.Keywords: mature teratoma, dermoid cyst, bladder tumor…”
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15867
Genetic Gain in Wheat Grain Yield and Nitrogen Use Efficiency at Different Nitrogen Levels in an Irrigated Hot Environment
Published 2020-01-01“…This gain was associated with progresses in harvest index (HI) at N43, N86, and N129 but not at N0. …”
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15868
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15869
Saffron therapy for the ongoing treatment of age-related macular degeneration
Published 2024-07-01“…Mean BCVA was 1.6 letters worse (p<0.05) with no difference between those on AREDS supplements or not, and this may have been related to cataract progression. No saffron-related serious adverse events were detected.Conclusion Saffron supplementation modestly improved mfERG responses in participants with AMD, including those using AREDS supplements. …”
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15871
Changes in the transcriptome of the prefrontal cortex of OXYS rats as the signs of Alzheimer’s disease development
Published 2015-12-01“…To elucidate how these signs develop, we used a nextgeneration RNA sequencing technique (RNA-Seq) to study the prefrontal-cortex transcriptome of OXYS rats during the manifestation of AD signs (at an age of 5 months) and during their active progression (at an age of 18 months), using age-matched Wistar rats (parental strain) as controls. …”
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15872
Requiem – Alàgbà, Dr., Prince, Mosọbalájé Ajíbádé Àkàndé Adébáyọ̀ Fálétí, OON, DLitt., FNAL, JP, a.k.a ‘Pa Fálétí’ to Some; ‘Bàbá Fálétí’ to all and Sundry....
Published 2021-12-01“…It is a testament to everything relational, from the ceremonial to the conventional to the familial! The progression from ‘Knowing of a person’ (mímọ ẹnì kan); ‘knowing something about that person’ (mímọ nǹkan nípa ẹni náà, mímọ ẹni náà); to ‘knowing that person well, personally’ (mímọ ènìyàn náà dáadáa) describes the various levels and depths of measuring knowledge of and/or familiarity with that person. …”
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15874
Modeling COVID-19 dynamics in the Basque Country: characterizing population immunity profile from 2020 to 2022
Published 2025-01-01“…Results The COVID-19 epidemic in the Basque Country progressed through three distinct phases, each shaped by dynamic interactions between virus transmission, public health interventions, and vaccination efforts. …”
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15875
Not all is lost: resilience of microbiome samples to freezer failures and long-term storage
Published 2025-01-01“…Such losses can halt research progress due to potential issues with sample reliability. …”
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15877
Metastatic pancreatic cancer now in remission: a case report and literature review
Published 2025-01-01“…Despite a stage IV diagnosis, the primary tumor was resected in order to mitigate the risk for mutation and progression. Although rare, greater hope for patients with PDAC of the tail with favorable tumor biology responsive to FOLFIRINOX may contribute to increased surgical resection rates and improve survival rates.…”
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15878
hERG activators exhibit antitumor effects in breast cancer through calcineurin and β-catenin-mediated signaling pathways
Published 2025-01-01“…While hERG channel is notoriously regarded as an off-target due to drug-induced cardiotoxicity, its therapeutic potential as a drug target remains largely unexplored.MethodsThis study investigated the role of hERG in breast cancer progression and its impact on patient survival. The anti-proliferative, anti-migratory, anti-invasive and pro-apoptotic effects of hERG activators were evaluated using the Cell Counting Kit-8, wound healing assay, transwell assay and cell apoptosis assay, respectively. …”
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15879
Relationship between dietary intake and atherogenic index of plasma in cardiometabolic phenotypes: a cross-sectional study from the Azar cohort population
Published 2025-02-01“…Abstract Background Cardiovascular diseases are a leading cause of global mortality, with diet playing a key role in their progression. The Atherogenic Index of Plasma (AIP) is a predictive marker for cardiovascular risk, but its association with dietary intake across cardiometabolic phenotypes remains underexplored. …”
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15880
Hormonal-Receptors-Positive and HER2-Negative Patients with Metastatic Breast Cancer Treated with First-Line Palbociclib and Hormonal Therapy: Impact of First-Cycle Neutropenia and...
Published 2023-01-01“…Dose reduction was recorded in 46.7% of patients and it was more common in patients with higher Allred scores (scores 7–8). The median progression-free survival (PFS) of the study group was 22 months. …”
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