Challenges and Prospects of Digital Core-Reconstruction Research by Linqi Zhu, Chong Zhang, Chaomo Zhang, Xueqing Zhou, Zhansong Zhang, Xin Nie, Weinan Liu, Boyuan Zhu

“…Additionally, 2D slice-based digital core stochastic reconstruction techniques are classified into four types: a stochastic reconstruction method based on 2D slice mathematical-feature statistical constraints, a stochastic reconstruction method based on statistical constraints that are related to 2D slice morphological characteristics, a physics process-based stochastic reconstruction method, and a hybrid stochastic reconstruction method. The progress related to these various stochastic reconstruction methods, the characteristics of constructed 3D digital cores, and the potential of these methods are analysed and discussed in detail. …”
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Evolving perspectives in dental marketing: A study of Jordanian dentists' attitudes towards advertising and practice promotion by Rami J. Anshasi, Nizar Alsubahi, Ahmad A. Alhusein, Abd Alwali Lutfi Khassawneh, Mahmaod Alrawad, Adi Alsyouf

“…Although the dental advertising landscape in Jordan has made considerable progress, research on dentists' perspectives regarding advertising in the country remains limited. …”
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Efficacy of a new treatment algorithm for capsulitis of the fingers in rock climbers by Volker Rainer Schöffl, Volker Rainer Schöffl, Volker Rainer Schöffl, Volker Rainer Schöffl, Volker Rainer Schöffl, Christoph Lutter, Christoph Lutter, Hans-Christoph Lang, Mario Perl, Othmar Moser, Michael Simon

“…A better understanding of the underlying pathogenesis is essential in order to better assess long-term progress.…”
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Harnessing artificial intelligence in sepsis care: advances in early detection, personalized treatment, and real-time monitoring by Fang Li, Shengguo Wang, Zhi Gao, Maofeng Qing, Shan Pan, Yingying Liu, Chengchen Hu

“…Sepsis remains a leading cause of morbidity and mortality worldwide due to its rapid progression and heterogeneous nature. This review explores the potential of Artificial Intelligence (AI) to transform sepsis management, from early detection to personalized treatment and real-time monitoring. …”
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Self-Examination Low-Cost Full-Field Optical Coherence Tomography (SELFF-OCT) for neovascular age-related macular degeneration: a cross-sectional diagnostic accuracy study by Peter Koch, Inke König, Johann Roider, Jan Tode, Konstantine Purtskhvanidze, Claus von der Burchard, Helge Sudkamp, Cristoph Ehlken, Moritz Moltmann, Britta Heimes, Michael Münst, Malte vom Endt, Timo Kepp, Dirk Theisen-Kunde, Gereon Hüttmann

“…Improvements are in progress to reduce device size and to improve handling, image quality and success rates.Trial registration number DRKS00013755, CIV-17-12-022384.…”
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Extracellular vesicles-derived miR-21 as a biomarker for early diagnosis and tumor activity in breast cancer subtypes by Claudia Omarini, Virginia Catani, Ilenia Mastrolia, Angela Toss, Federico Banchelli, Chrystel Isca, Daniele Medici, Ornella Ponzoni, Marco Brucale, Francesco Valle, Maria Cristina Baschieri, Roberto D’Amico, Valentina Masciale, Chiara Chiavelli, Federica Caggia, Carlo Augusto Bortolotti, Federico Piacentini, Massimo Dominici

“…We assessed EV-derived miR-21 levels in one hundred women: 30 with early BC (EBC), 30 with metastatic BC on treatment progression (MBC), 30 cancer survivors on follow-up (FU) and 10 healthy donors (HD) as age- and body mass index (BMI)-matched controls. …”
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An investigator-blinded, 24-month, parallel-group, non-inferiority study to compare aesthetic restorations in primary anterior teeth in a paediatric dental clinic: study protocol f... by Ana Paula Taboada Sobral, Elaine Marcilio Santos, Marcela Leticia Leal Gonçalves, Lara Jansiski Motta, Anna Carolina Ratto Tempestini Horliana, Sandra Kalil Bussadori, Elza Padilha Ferri, Juliana Maria Altavista Sagretti Gallo, Thais Gimenez, José Carlos Pettorossi Imparato

“…The explanatory variables—gender, age, toothbrushing, use of fluoridated toothpaste and dental floss, and socioeconomic status—will be collected through a questionnaire with open questions. The progression of caries lesions after 24 months of follow-up will be considered as the primary outcome. …”
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INdependenT prEscribinG in community phaRmAcy; whaT works for whom, why and in what circumstancEs (INTEGRATE): Realist review study protocol [version 1; peer review: 2 approved] by Andrew Sturrock, Tony Kelly, Vivienne Hibberd, Ian Maidment, Ola Amr Abdelfatah, Nia Roberts, Ellen Schafheutle, Andrea Hilton, Keith Holden, Geof Wong, Nick Haddington, Lesley Scott

“…Method and analysis Realist research seeks to explore and explain complex social interventions by utilising programme theories providing causal explanations of outcomes in terms of context-mechanism-outcome configurations. INTEGRATE will progress through six stages. In the first stage, we will partner with Patient, Public, Involvement and Engagement Group (PPIE) and Practitioner Stakeholder Group (SG), to further scrutinise the review’s focus. …”
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Deregulated methylation and expression of PCDHGB7 in patients with non-small cell lung cancer: a novel prognostic and immunological biomarker by Yue Yuan, Yue Yuan, Xin Nie, Jiayi Gao, Jiayi Gao, Yumeng Tian, Yumeng Tian, Liuer He, Liuer He, Xue Wang, Ping Zhang, Junling Ma, Lin Li, Lin Li

“…Patients with PCDHGB7 hypermethylation in baseline plasma had shorter progression-free survival (PFS) and overall survival (OS), while those with early reduction of PCDHGB7 methylation had the best prognosis. …”
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Quantifying research hotspots and trends in brucella spondylitis: a bibliometric analysis by Zhangui Gu, Zhangui Gu, Zongqiang Yang, Zongqiang Yang, Le Fei, Le Fei, Daihao Wei, Daihao Wei, Long Ma, Qiang Liu, Jiandang Shi

“…Analysis of abstracts and keyword trends revealed that post-2020, emerging research frontiers include “instrumentation,” “management,” and “debridement.”ConclusionThere has been significant progress in BS research, with a steady increase in publications. …”
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Human Herpesviruses, Bacteria, and Fungi in Gingivitis and Periodontitis Pediatric Subjects: A Systematic Review by Federica Di Spirito, Massimo Pisano, Mario Caggiano, Giuseppina De Benedetto, Maria Pia Di Palo, Gianluigi Franci, Massimo Amato

“…<b>Conclusions:</b> These findings highlight the role of microbial interactions in periodontal health and disease progression.…”
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Intestinal flora composition and fecal metabolic phenotype in elderly patients with sleep disorders combined with type 2 diabetes by Zhuohao Yin, Huaze Xie, Fuyuan Liu, Xue Kong, Wei Chen, Yangfan Gong, Wei Ge

“…Variations in intestinal flora and metabolism significantly influence the onset and progression of the ESdD group.…”
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PD-L1 monoclonal antibody alleviated MI injury of left ventricular function via modulating CD47/SHP2/SIRPα/SYK/FcγR signalings in tumor associated macrophages by Deyou Kong, Yongzhen Chen, Yajuan Yin, Zhikun Liu, Fang Yang, Xiaohong Li, Dongxing Shen, Jun Zhang

“…Both cGAMP content measurement and Masson staining results indicated that PD-L1 mAb had a therapeutic effect on mice with breast cancer and MI, improving the infarct condition and slowing tumor progression. In vitro Western blotting analysis revealed that PD-L1 mAb can modulate the CD47/SHP2/SIRPα/SYK/FcγR signaling pathway, thereby affecting breast cancer. …”
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Mf-net: multi-feature fusion network based on two-stream extraction and multi-scale enhancement for face forgery detection by Hanxian Duan, Qian Jiang, Xin Jin, Michal Wozniak, Yi Zhao, Liwen Wu, Shaowen Yao, Wei Zhou

“…Therefore, researchers have worked on face forgery detection studies and have made significant progress. Current face forgery detection algorithms achieve high detection accuracy within-dataset. …”
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Exploring the impact of insufficient thermal ablation on hepatocellular carcinoma: NDST2 overexpression mechanism and its role in facilitating growth and invasion of residual cance... by Weijun Wan, Danxia Guo, Tong Kang, Jinshu Pang, Yunjing Pan, Jiamin Chen, Wei Liao, Yuji Chen, Peng Lin, Lipeng Li, Hong Yang, Yun He

“…Knockdown of NDST2 in heat stress-induced liver cancer cells results in growth inhibition associated with gene downregulation.Conclusion The upregulation of NDST2 can accelerate the progression of residual HCC after ITA, suggesting a potential role for NDST2 in the therapeutic efficacy and prognosis of residual HCC.…”
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Characteristics of NAFLD Based on Hypopituitarism by Kazuhisa Kodama, Atsuhiro Ichihara, Yasufumi Seki, Yuichi Ikarashi, Takaomi Sagawa, Tomomi Kogiso, Maiko Taniai, Katsutoshi Tokushige

“…The hepatic fibrosis grade rapidly progressed in the cranial surgery cases of NAFLD patients with hypopituitarism, possibly in association with BMI, diabetes mellitus, and leptin. …”
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Clinical outcomes of dogs with high-grade cutaneous mast cell tumors by Siew Mei Ong, Siew Mei Ong, Charly McKenna, Christopher Pinard, Christopher Pinard, Christopher Pinard, Christopher Pinard, Danielle Richardson, Michelle L. Oblak

“…Despite aggressive treatment, 75% of the dogs that received concurrent surgical and adjuvant therapy experienced disease progression. Lymph node extirpation, tumor localization, number of tumors, and local recurrence were not associated with the overall outcome.Clinical relevanceThe combination of aggressive local therapy and adjuvant systemic chemotherapy provides a notable survival benefit in dogs with HGMCTs. …”
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Impact of solid fuel use on asthma prognosis and consistent peak expiratory flow changes: Evidence from China by Yuexi Chen, Shuojia Xie, Xirong Chen, Xiaowen Zhong, Linhang Yang, Weitong Lin, Junfeng Huang, Ruchong Chen

“…Yet the connection between use of such fuels and the incidence as well as the progression of asthma needs further clarification. This investigation endeavors to conduct an integrative cross-sectional and longitudinal study to examined the link between solid fuel utilization and asthma. …”
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Associations of plasma biomarkers with cerebral perfusion and structure in Alzheimer’s disease by Yong He, Xiaojiao Liu, Fang Liu, Ping Che, Yanxin Zhang, Ruxue Fan, Yuan Li, Wen Qin, Nan Zhang

“…Plasma biomarkers exhibited varied correlations with brain perfusion, GM volume, and WM integrity and predicted their longitudinal changes in AD patients, suggesting their potential to reflect functional and structural changes and to monitor pathophysiological progression in the brain.…”
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Current status and development trends of deep coalbed methane research in China by Wei JU, Shu TAO, Zhaobiao YANG, Jiayao CHENG, Haiyan SHANG, Weike NING, Chunlong WU

“…The results indicate that the temporal distribution of publications reflects the evolution of China's deep CBM research and industrial development, which can be divided into four stages: the initial exploration stage (1994 to 2005), the slow development stage (2006 to 2015), the steady progress stage (2016 to 2020), and the rapid development stage (since 2021). …”
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