Organizational factors impacting the implementation of a digital mental health tool in Alberta's mental health care of youth and young adults by Marianne Barker, Julia Hews-Girard, Karina Pinston, Sarah Daniel, Lauren Volcko, Lia Norman, Emilie Bassi, Katherine Bright, Ian Hickie, Frank Iorfino, Haley LaMonica, Karen Moskovic, Melanie Fersovitch, Jessica Bradley, Leanne Stamp, Jason Gondziola, David Johnson, Gina Dimitropoulos

“…This qualitative study explores organizational barriers and facilitators surrounding the implementation of a digital platform (Innowell), which uses measurement-based care (MBC) to track youth progress and outcomes. Data was collected from 154 mental health care providers participating in 23 focus groups across Alberta, drawing on school and community settings, specialized mental health services, and primary care networks. …”
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Dual specific STAT3/5 degraders effectively block acute myeloid leukemia and natural killer/T cell lymphoma by Daniel Pölöske, Helena Sorger, Anna Schönbichler, Elvin D. deAraujo, Heidi A. Neubauer, Anna Orlova, Sanna H. Timonen, Diaaeldin I. Abdallah, Aleksandr Ianevski, Heikki Kuusanmäki, Marta Surbek, Elisabeth Heyes, Thomas Eder, Christina Wagner, Tobias Suske, Martin L. Metzelder, Michael Bergmann, Maik Dahlhoff, Florian Grebien, Roman Fleck, Christine Pirker, Walter Berger, Emir Hadzijusufovic, Wolfgang R. Sperr, Lukas Kenner, Peter Valent, Tero Aittokallio, Marco Herling, Satu Mustjoki, Patrick T. Gunning, Richard Moriggl

“…JPX‐0700/−0750 decreased the mRNA and protein levels of STAT3/5 targets involved in cancer survival, metabolism, and cell cycle progression, exhibiting nanomolar to low micromolar efficacy. …”
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Severe anti-α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor encephalitis with prolonged hyperammonemia: a case report by Chunxia Yan, Lingling Bai, Jingwei Du, Zonglei Chong, Guangjun Xu, Xiaoqian Yang

“…The patient’s condition rapidly progressed to coma, which persisted for 2 months, manifesting as a fulminant course. …”
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Exercise training and chronic kidney disease: characterization and bibliometrics of citation classics of clinical intervention trials by Fan Zhang, Shan Liu, Yan Bai, Liuyan Huang, Yifei Zhong, Yi Li

“…Background Exercise research targeting chronic kidney disease (CKD) has been conducted for more than 30 years, and the benefits of exercise for CKD patients have been progressively demonstrated. This study analyzes citation classics on clinical intervention trials on exercise training and CKD to describe the research landscape and hotspots through bibliometric analysis.Methods To identify clinical trials of exercise training interventions for CKD with more than 100 citations from the Web of Science Core Collection database. …”
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Hypoxia signature derived from tumor-associated endothelial cells predict prognosis in gastric cancer by Ruiheng Wang, Ruiheng Wang, Guijun Liu, Guijun Liu, Ke Wang, Zhanglei Pan, Zhanglei Pan, Zhihua Pei, Xijiao Hu, Xijiao Hu

“…BackgroundA hypoxic metabolism environment in the tumors is often associated with poor prognostic events such as tumor progression and treatment resistance. In gastric cancer, the mechanism of how hypoxia metabolism affects the tumor microenvironment and immunotherapy efficacy remains to be elucidated.MethodsWe used the bulk-mapping method to analyze the signatures correlated with the response of immunotherapy in the single-cell dataset. …”
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Whole transcriptome analysis of unmutated sporadic ALS patients' peripheral blood reveals phenotype-specific gene expression signature by Francesca Dragoni, Maria Garofalo, Rosalinda Di Gerlando, Bartolo Rizzo, Matteo Bordoni, Eveljn Scarian, Camilla Viola, Veronica Bettoni, Giuseppe Fiamingo, Danilo Tornabene, Lucia Scanu, Orietta Pansarasa, Luca Diamanti, Stella Gagliardi

“…There are no well-established molecular biomarkers for early diagnosis, prognosis, and progression monitoring of this fatal disease. Classification based on clinical phenotypes could be associated with peculiar gene expression patterns shaped during lifespan, allowing the identification of specific sporadic ALS (sALS) subtypes with less heterogeneous clinical and biological features. …”
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Multiscale Attention Feature Fusion Based on Improved Transformer for Hyperspectral Image and LiDAR Data Classification by Aili Wang, Guilong Lei, Shiyu Dai, Haibin Wu, Yuji Iwahori

“…This structure combines the advantages of the Swin transformer, featuring a nonlocal receptive field fusion by progressively expanding the window's receptive field layer by layer while preserving the spatial features of the image. …”
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Aurora kinase A expression in pleomorphic adenoma, adenoid cystic carcinoma, and mucoepidermoid carcinoma of salivary glands: an immunohistochemical study by Razieh Zare, Leila Izadi, Mario Alberto Alarcón-Sánchez, Masumeh Taghva, Mohammad Ali Ranjbar

“…Abstract Background Aurora kinase A (AurkA) plays a vital role in mitosis and is therefore critical in tumors development and progression. There are a few studies on AurkA expression in salivary gland tumors. …”
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Improving the provision of clinical pharmacy services in low- and middle-income countries: a qualitative study in tertiary health facilities in Tanzania by Fredrick Kalokola, Dorkasi L Mwakawanga, Ritah F Mutagonda, Hamu J Mlyuka, Wigilya P Mikomangwa, Manase Kilonzi, Wema A Kibanga, Alphonce Ignace Marealle, Bertha Mallya, Deogratias Katabalo, Sofia Sanga, John Rwegasha, Rose Magambo, John Mmassy, Sungwa Kabissi, Josephine A Balati, Peter Maduki, Omary Mashiku Minzi, Appolinary A R Kamuhabwa

“…The latter calls for multifaceted engagement from pharmacists, training institutions, policymakers, regulatory bodies and health systems for sustainable progress.…”
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Serum proteomic and metabolomic profiling of hepatocellular carcinoma patients co-infected with Clonorchis sinensis by Zeli Tang, Zeli Tang, Zeli Tang, Caibiao Wei, Xueling Deng, Qiumei Lin, Qiping Hu, Qiping Hu, Qiping Hu, Shitao Li, Jilong Wang, Yuhong Wu, Dengyu Liu, Dengyu Liu, Dengyu Liu, Min Fang, Min Fang, Tingzheng Zhan, Tingzheng Zhan, Tingzheng Zhan

“…Key molecules ILF2, CNN2, OLFM4, NOTCH3, and LysoPA were implicated in HCC progression. Furthermore, C. sinensis triggered inflammation, insulin resistance, and pro-tumor immune escape, and exacerbated the complication of degenerative diseases.ConclusionThis study not only provides compelling evidence for elucidating the mechanisms underlying C. sinensis-mediated HCC development but also identifies potential therapeutic targets for HCC patients co-infected with C. sinensis.…”
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A novel machine learning-based immune prognostic signature for improving clinical outcomes and guiding therapy in colorectal cancer: an integrated bioinformatics and experimental s... by Yuanchun Zhao, Dexu Xun, Jiajia Chen, Xin Qi

“…Abstract Immune cells are pivotal components in the tumor microenvironment (TME), which can interact with tumor cells and significantly influence cancer progression and therapeutic outcomes. Therefore, classifying cancer patients based on the status of immune cells within the TME is increasingly recognized as an effective approach to identify prognostic biomarkers, paving the way for more effective and personalized cancer treatments. …”
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FGF23-related hypophosphatemia in a patient with small cell lung cancer: a case report and literature review by Hajime Kato, Soichiro Kimura, Maho Taguchi, Takashi Sunouchi, Yoshitomo Hoshino, Naoko Hidaka, Nadia Edvige Foligno, Minae Koga, Katsunori Manaka, Hiroyuki Tamiya, Masanori Kawakami, Hidenori Kage, Yoichi Yasunaga, Masaomi Nangaku, Noriko Makita, Nobuaki Ito

“…Even after two subsequent courses of chemotherapy, the small cell lung cancer progressed, and the FGF23 level was further elevated (83.7 pg/mL). …”
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Advances in carbon dioxide capture and conversion technologies: Industrial integration for sustainable chemical production by Okezie Emmanuel, Rozina, Thaddeus C. Ezeji

“…This review highlights significant progress made in CO2 capture and its integration into various industrial applications. …”
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Clinical profile, treatment, and outcomes of testicular cancer in a resource-limited setting: a study from Sudan by Eltahir Ahmed Eltahir, Sami Mahjoub Taha Awad, Yassin Mohammed Osman, Mohammed El Imam Mohammed Ahmed, Moawia Mohammed Ali Elhassan

“…At the last follow-up, 44% of patients were in remission, 18% were alive with disease progression, and 36% had died. Conclusions This study highlights the high mortality rate associated with testicular cancer in this resource-limited setting, which is likely due to delayed diagnosis and the advanced stage at presentation. …”
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Culinary Arts: A Motivator Towards Community-Based Festival Attendance and Sustainability by Ibraheem Kukoyi, Abioye Adedipe, Tajudeen Yusuf, Opeyemi Ijaya

“…The study concludes that culinary arts motivates peoples’ attendance at festivals and therefore recommends sustaining the inclusion of culinary activities in other community-based festivals to promote attendance for the progress of the festivals and its sustainability.…”
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Assessing the dynamics of  Mycobacterium bovis infection in three French badger populations by Calenge, Clément, Payne, Ariane, Réveillaud, Édouard, Richomme, Céline, Girard, Sébastien, Desvaux, Stéphanie

“…This participatory program, involving both national and local stakeholders, allowed us to monitor the progression of the infection in three badger populations in clusters covering between 3222 km2 and 7698 km2 from 2013 to 2019. …”
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Relationship between Cognitive Learning Psychological Classification and Neural Network Design Elements by Xing Yang, Tingjun Yong, Meihua Li, Wenying Wang, Huichun Xie, Jinping Du

“…Through the exploratory research on cognitive psychology in neural network design, we can see that the combination of neural network design and psychology, art aesthetics, and other cross-disciplinary and multidisciplinary research is necessary, which can promote the scientific and technological progress of neural network design in the context of the information age and the improvement of public mental health. …”
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Expression Levels of IL-17A, IL-17F, IL-17RA, and IL-17RC in Prostate Cancer with Taking into Account the Histological Grade according to Gleason Scale in Comparison to Benign Pros... by Marlena Janiczek, Łukasz Szylberg, Paulina Antosik, Anna Kasperska, Andrzej Marszałek

“…Evaluation of proinflammatory factors such as IL-17A, IL-17F, IL-17RA, and IL-17RC expression makes it possible to assess the impact of inflammatory process on progression of PCa. The aim of the study was to retrospectively assess the histological material of PCa divided into few groups using the Gleason score. …”
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Macrophage Activities in Myocardial Infarction and Heart Failure by Sophia Esi Duncan, Shan Gao, Michael Sarhene, Joel Wake Coffie, Deng Linhua, Xingru Bao, Zhang Jing, Sheng Li, Rui Guo, Jing Su, Guanwei Fan

“…Macrophage population is active in inflammatory process, yet the clear understanding of the causative roles for these macrophage cells in HF development and progression is actually incomplete. Long ago, it was thought that macrophages are of importance in the heart after MI. …”
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The Canadian Bronchiectasis and Nontuberculous Mycobacteria Registry: a study protocol by Christina S. Thornton, Nicole Boechler, Vidhi Desai, Ranjani Somayaji, Swathi Purighalla, Sarah Brode, Theodore K. Marras, Ryan Cooper, Maeve Smith, Julie Jarand

“…The comprehensive Canadian Bronchiectasis and Nontuberculous Mycobacterial (NTM) Registry aims to 1) outline the clinical characteristics and natural history of bronchiectasis in Canada, 2) identify risk factors contributing to disease progression within Canadians, 3) integrate comprehensive clinical information to better understand the phenotypes of bronchiectasis and 4) support the development of large-scale, randomised controlled trials in Canada. …”
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