STUDY OF THE EFFECT OF HYPOTHERMIC CONSERVATION ON THE INTRACELLULAR SODIUM CONCENTRATION IN THE ENDOTHELIUM OF CORNEAL TRANSPLANTS by G. S. Baturina, I. G. Palchikova, A. A. Konev, E. S. Smirnov, L. E. Katkova, E. I. Solenov, I. А. Iskakov

“…Advancements in the surgical treatment of corneal endothelial diseases depend on progress in graft conservation and its related advantages in assessing the suitability of grafts for transplantation. …”
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Valproic Acid Enhances Venetoclax Efficacy in Targeting Acute Myeloid Leukemia by Renshi Kawakatsu, Kenjiro Tadagaki, Kenta Yamasaki, Yasumichi Kuwahara, Tatsushi Yoshida

“…Cell viability was assessed using the trypan blue dye exclusion assay, while cell cycle progression was analyzed by flow cytometry. The expression of pro-apoptotic proteins Bax and Bak was measured by RT-qPCR. …”
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The protective roles of eugenol on type 1 diabetes mellitus through NRF2-mediated oxidative stress pathway by Yalan Jiang, Pingping He, Ke Sheng, Yongmiao Peng, Huilan Wu, Songwei Qian, Weiping Ji, Xiaoling Guo, Xiaoou Shan

“…Type 1 diabetes mellitus (T1DM), known as insulin-dependent diabetes mellitus, is characterized by persistent hyperglycemia resulting from damage to the pancreatic β cells and an absolute deficiency of insulin, leading to multi-organ involvement and a poor prognosis. The progression of T1DM is significantly influenced by oxidative stress and apoptosis. …”
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Mosaic Structure of GaN Film Grown on Sapphire Substrate by AP-MOCVD: Impact of Thermal Annealing on the Tilt and Twist Angles by J. Laifi, M. F. Hasaneen, H. Bouazizi, Fatimah Hafiz Alsahli, T. A. Lafford, A. Bchetnia

“…The intensity and broadening of the yellow band (YL) in the PL spectra progressively increased with the increasing annealing temperature, suggesting the presence of additional defect states. …”
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Effect of Double Masking with Silk or Cotton Over-masks on the Source Control Capabilities of a Surgical Mask by Adam F. Parlin, Mikhail Yermakov, Samuel M. Stratton, Susan R. Reutman, Theresa M. Culley, Patrick A. Guerra, Sergey A. Grinshpun

“…Abstract In spite of the remarkable progress made in the development of safe and effective vaccines against COVID-19, deployment of respiratory protective devices remains vital for mitigating the transmission of SARS-CoV-2 during the ongoing pandemic. …”
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Sulfatase modifying factor 2 as a predictive biomarker for urothelial carcinoma by Wei-Ting Kuo, Yi-Chen Lee, Jia-Bin Liao, Ching-Jiunn Tseng, Yi-Fang Yang

“…Abstract Sulfatases mediate the sulfation level of cell-surface heparan sulfates to regulate signal transduction, thereby promoting cancer progression. Sulfatase activation requires a sulfatase modifying factor (SUMF) for the modification of its catalytic domain. …”
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Exploring nanocomposite materials in clinical dermatology: Innovations for treating skin diseases by Sandipan Dasgupta, Subhasundar Maji, Sanjay Dey, Moitreyee Chattopadhyay, Ananya Chanda, Satarupa Acharjee, Kousik Santra, Kazi Asraf Ali

“…The future of nanocomposites in dermatology looks promising, with innovations in personalized medicine, smart drug delivery, and multifunctional materials driving progress. Continued research and development will be essential to unlock the full potential of nanocomposites in enhancing clinical dermatology. …”
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Evaluation of the association between bevacizumab concentration and clinical outcomes in patients with breast cancer brain metastasis by Chih-Ning Cheng, Yun-Jung Tsai, Huai-Hsuan Chiu, Tom Wei-Wu Chen, Ching-Hung Lin, Yen-Sheng Lu, Ching-Hua Kuo

“…Although bevacizumab concentrations did not associate with therapeutic response and progression-free survival, patients with higher bevacizumab concentrations exhibited longer overall survival (adjusted HR 0.78; p = 0.039). …”
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miR-134-3p Regulates Cell Proliferation and Apoptosis by Targeting INHBA via Inhibiting the TGF-β/PI3K/AKT Pathway in Sheep Granulosa Cells by Xinai Huang, Yongjin Bao, Fan Yang, Xiaodan Li, Feng Wang, Chunxiang Zhang

“…Moreover, cell cycle progression was enhanced by miR-134-3p overexpression. …”
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Platycodin D inhibits tumor proliferation by modulating macrophage polarization through promoting JAK2 ubiquitination by Wei Wu, Jie Zhang, Zijiao Wang, Chuan Cheng, Dongdong Yuan, Li Peng, Le Li

“…A growing body of evidence indicates that tumor-associated macrophages (TAMs) are crucial contributors to cancer progression, positioning them as an attractive target for therapeutic intervention. …”
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The pro-inflammatory cytokine Tumor Necrosis Factor alpha (TNF-α) in Diabetic Nephropathy by Alia KH Mahmoud, Muhammed Ahmed Abd El Moety, Amal Khalifa Ahmed, Samer A. El-Sawy

“…Regretfully, we still don't fully understand the mechanisms underlying the onset and progression of renal injury in diabetes. There is now proof that inflammation and activated innate immunity play important roles in the etiology of problems with diabetes. …”
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CD4+CD25highCD127low/−FoxP3+ Regulatory T Cell Subpopulations in the Bone Marrow and Peripheral Blood of Children with ALL: Brief Report by M. Niedźwiecki, O. Budziło, M. Zieliński, E. Adamkiewicz-Drożyńska, L. Maciejka-Kembłowska, T. Szczepański, P. Trzonkowski

“…This small subset of T cells has been, in fact, considered to be involved in the pathogenesis of autoimmune diseases and progression of acute and chronic leukemias. However, whether Treg dysregulation in CLL and ALL plays a key role or it rather represents a simple epiphenomenon is still a matter of debate. …”
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CASE REPORT ON TWO CONSECUTIVE PATIENTS WITH NEUROINVASIVE WEST NILE VIRUS INFECTION IN AN INTENSIVE CARE UNIT by Silviya Stoyanova, Raynichka Mihaylova-Garnizova, Emilia Naseva, Severina Dakova, Iva Christova, Konstantin Ramshev

“…The first case was a 60-year-old man who have had mental status changes, fever, and progression of existing Parkinson's disease. Antibodies to WNV were present in cerebrospinal fluid (CSF). …”
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Quantitative Analysis of Postural Instability in Patients with Parkinson’s Disease by Yang Yu, Siquan Liang, Yue Wang, Yanan Zhao, Jiaojiao Zhao, Haitao Li, Jingchao Wu, Yuanyuan Cheng, Fan Wu, Jialing Wu

“…Postural instability is commonly observed in Parkinson’s disease, leading to an increasing risk of falling and worsening as the disease progresses. We found that limit of stability can be applied to reflect the dynamic evolution of postural instability in patients with Parkinson's disease. …”
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The small modular molten salt reactor potential and opportunity in Saudi Arabia by Dana Hejazi, Anas M. Alwafi, Salman M. Alzahrani, Meshari M. Alqahtani, Salman M. Alshehri

“…The adoption of MSRs presents an opportunity for groundbreaking research, economic diversification, and progression towards a sustainable energy future. With rising energy demands and the need to transition towards cleaner sources, nuclear energy is poised to play a vital role globally and in Saudi Arabia’s future energy mix. …”
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Health-related quality of life outcomes reporting associated with FDA approvals in haematology and oncology by Bishal Gyawali, Pallawi Torka, Kristopher Attwood, Medhavi Gupta, Othman Salim Akhtar, Bhavyaa Bahl, Angel Mier-Hicks, Kayla Catalfamo

“…Proportion of included trials that reported HRQoL, latency between FDA approval and first report of HRQoL data, HRQoL outcomes, and their correlation with OS (overall survival) and PFS (progression-free survival) were analysed.Results Of the 233 trials associated with 207 FDA approvals, HRQoL was reported in 50% of trials, of which only 42% had the data reported by the time of FDA approval. …”
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Did selective kinase inhibitors change the management of patients with radioiodine-refractory thyroid cancer? by Tommaso Porcelli, Cristina Luongo, Anna Cerbone, Carmine Di Luccio, Mariantonia Nacchio, Maria Angela De Stefano, Martin Schlumberger, Domenico Salvatore

“…Grade ≥3 adverse events occurred in 13 (42%) patients treated with lenvatinib and only in 1 (9%) patient treated with DT. Progression-free survival (PFS) and overall survival rates at 1 year were 72% and 83% in lenvatinib-treated patients and 69% and 83% in DT-treated patients, respectively. …”
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Implementation of a value-based approach for older people who have suffered an acute myocardial infarction: study protocol by Denis Juraga, Tomislav Rukavina, Tomislav Rukavina, Mihaela Marinović Glavić, Lovorka Bilajac, Lovorka Bilajac, Lovorka Bilajac, Aleksandar Racz, Esmee L. S. Bally, Oscar Zanutto, Tamara Alhambra-Borrás, Maite Ferrando, Alen Subotić, Hein Raat, Vanja Vasiljev

“…Together with smartwatches, which will track important health aspects, and applications, this approach would enable older people to improve their health through correct lifestyle choices and their professional and informal caregivers to track their progress. With the use of the described technology and the multidisciplinary approach, the unmet needs and values of participants could be achieved. …”
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Blood levels of cytokines highlight the role of inflammation in Alzheimer's disease by Lorenzo Campanelli, Pablo Galeano, Federico A. Prestia, Carolina Cuesta, Maria C. Dalmasso, María Flores-López, Cristian Gona, Nicolás Irureta, Claudia Kairiyama, Julieta Lisso, Antonio Jesús López-Gambero, Ines Mintz, Nancy Medel, Karen S. Campuzano, Carolina Muchnik, Gisela V. Novack, Natividad Olivar, Ivana Quiroga, Nerea Requena-Ocaña, Jose Antonio Reyes-Bueno, Pedro Serrano-Castro, Zulma Sevillano, Patricia Solis, Juan Suárez, Ivana Villella, Nancy Wukitsevits, Eduardo M. Castaño, Fernando Taragano, Silvia Kochen, Daniel G. Politis, Luis I. Brusco, Fernando Rodríguez de Fonseca, Laura Morelli

“…Inflammation and angiogenesis have been defined as potential mechanisms associated with clinical progression from a cognitively normal state to Alzheimer's disease (AD). …”
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Beyond buzzwords: fostering interdisciplinary and collaborative global health research in Germany and beyond by Maeve Cook-Deegan, Kerem Böge, Walter Bruchhausen, Mizeck Chagunda, Medha Chaturvedi, Meral Esen, Johanna Hanefeld, Beate Kampmann, Carsten Köhler, Charlotte Köhler, Francis Osei, Clarissa Prazeres da Costa, Eva Rehfuess, Thirumalaisamy P. Velavan, Nora Anton, on behalf of the GLOHRA Steering Committee**

“…Sustained, longer-term federal funding mechanisms will also be essential for ongoing progress.…”
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