Macrophage MST1 protects against schistosomiasis-induced liver fibrosis by promoting the PPARγ-CD36 pathway and suppressing NF-κB signaling. by Jianyang Li, Xinyuan Cai, Yan Yang, Yulin Mao, Lin Ding, Qian Xue, Xunhao Hu, Yan Huang, Cong Sui, Yuxia Zhang

“…Monocyte-derived macrophages play critical and plastic roles in the progression and regression of liver fibrosis, adopting different polarization phenotypes. …”
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Electrodiagnostic assessment of autonomic nervous system in diabetic autonomic neuropathy: Case series in 72 diabetes patients by Suchitra Dube, Sandip M. Hulke, Santosh L. Wakode, Sagar Khadanga

“…Hence HRV and AFT are performed to detect and prevent its progression to advanced stages. To discuss the HRV and AFT findings in diabetic patients. …”
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中空夹层圆钢管混凝土短柱的压弯承载力计算法 by 谌扬宇, 宁寄慧, 张永鑫, 刘思威, 黎学优

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Attention-Based Image-to-Video Translation for Synthesizing Facial Expression Using GAN by Kidist Alemayehu, Worku Jifara, Demissie Jobir

“…With the development of generative adversarial networks (GANs), great progress has been made in image generation tasks which can be used for facial expression synthesis. …”
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Investigation on Seismic Performance of Bidirectional Self-Centering Reinforced Concrete Frame Structures by Shaking Table Tests by Zhenying Wang, Chenxi Mao, Lili Xie

“…The natural frequencies of the self-centering frames installed in both the directions degraded progressively, mainly because of the prestress loss of the PT steel wires and the yielding of the MS dampers. …”
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Defense strategy of industrial control worm based on SEIPQR model by Jie PAN, Lan YE, He ZHAO, Xinlei ZHANG

“…Computer viruses keep evolving with the development of society and progress of technologies, and they become more complex and hidden.The worm virus is the earliest computer virus, which has evolved to an industrial control worm virus and caused a great impact on the safety of the industrial system.Neither the single network isolation nor the patching immunity is unable to keep up with the spreading of the worm virus.The propagation mode and characteristics of the worm virus in the industrial control system were analyzed.Based on the related works of network isolation and patching, a defense strategy against the worm virus was proposed.This strategy was originated from the fundamental infectious disease model, and then a mathematics model (SEIPQR) was proposed to simulate the trend of worm virus propagation.The model included six situations: Susceptible, Exposed, Infected, Quarantine and Recovered.The state transition diagrams of the model was created, and the calculus equations were obtained from the state transition diagrams.Under the condition that the number of system equipment is fixed, the equations were transformed.The equations were solved by solving the basic regeneration number R0, and six equation expressions of the model ware analyzed when the number of exposed hosts and infected hosts is zero.According to the principle of the Routh-Hurwitz, the system is asymptotically stable when R₀＜1, and unstable if R₀＞1.Then the dynamic characteristics of the SEIPQR model under different patching probability, different isolation rate and different infection rate were compared by numerical simulation.Furthermore, the disease-free equilibrium point and endemic equilibrium point of the model were obtained.The simulation results showed that, when the whole system is infected with worm virus, timely patching the susceptible devices and isolating the network can effectively inhibit the spread of industrial control worm virus.…”
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装配式工字钢腹板开孔屈服耗能支撑滞回性能分析 by 孙筱玮, 赵宝成, 沈晓明

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Governance and Poverty Eradication Policy Performance During the NRM Administration in Uganda 1986 – 2020. by Mucunguzi, Abel, Katabaazi, Anny Bwengye

“…The idea behind this research is that if the causes of the slow progress in poverty reduction are not identified and targeted holistically through policy and inculcation of good governance at all levels of government administration, it will be difficult for Uganda to achieve significant poverty reduction and eradication in the long run. …”
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Governance and poverty eradication policy performance during the NRM1 Administration in Uganda 1986 – 2020 by Mucunguzi, Abel, Bwengye, Katabaazi Anny

“…The idea behind this research is that if the causes of the slow progress in poverty reduction are not identified and targeted holistically through policy and inculcation of good governance at all levels of government administration, it will be difficult for Uganda to achieve significant poverty reduction and eradication in the long run. …”
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Assessing the Hydraulic Performance of Ntungamo Town Piped Water Distribution System. by Ahimbisibwe, James

“…Water distribution networks are crucial for regional development, as they serve multiple purposes beyond providing water for human consumption, directly influencing a nation's progress. Reliable water supply, a key component of these networks, plays a vital role in sustaining and improving public quality of life. …”
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Urbanisation and Education Development: A Case Study of Rock High School. by Abaho, Derick

“…Additionally, upgrading infrastructure and monitoring progress through data-driven evaluations are crucial for adapting to ongoing changes.…”
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University Governing Council Report 2019/20 - 2023/24 by Kabale University

“…The University’s growing staff and student numbers are presented as indicators of its progress. It is evident from the report that the number of publications and research is increasing. …”
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Influence of Parents’ Socio-Economic Status on Pupils’ Academic Performance in Primary Schools of Kabale Municipality by Wilberforce, Nabaasa

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Trifluridine-tipiracil in previously treated patients with oestrogen receptor-positive, HER2-negative metastatic breast cancer (BOOG 2019-01 TIBET trial): a single-arm, multicentre... by Niels A.D. Guchelaar, Ron H.J. Mathijssen, Maaike de Boer, Marlies L. van Bekkum, Joan B. Heijns, Birgit E.P.J. Vriens, Mandy M. van Rosmalen, Lonneke W. Kessels, Lisanne Hamming, Karin J. Beelen, Peter Nieboer, Susan M. van den Berg, Esther Oomen-de Hoop, Rhodé M. Bijlsma, Monique E.M.M. Bos

“…The participants received trifluridine-tipiracil 35 mg/m2 orally twice a day on days 1–5 and days 8–12 during a 28-day cycle until disease progression, unacceptable toxicity, or withdrawal of consent. …”
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First-line chemotherapy with selective internal radiation therapy for intrahepatic cholangiocarcinoma: The French ACABi GERCOR PRONOBIL cohort by Nicolas Adamus, Julien Edeline, Julie Henriques, Nadim Fares, Thierry Lecomte, Anthony Turpin, Dewi Vernerey, Mathilde Vincens, Brice Chanez, David Tougeron, Christophe Tournigand, Eric Assenat, Matthieu Delaye, Sylvain Manfredi, Olivier Bouché, Nicolas Williet, Angelique Vienot, Lorraine Blaise, Léo Mas, Cindy Neuzillet, Alice Boilève, Gaël S. Roth

“…The primary outcome was progression-free survival (PFS). Secondary outcomes were overall survival (OS), objective response rate (ORR) and tumor resection rate. …”
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A phase 2, double-blind, placebo-controlled trial of a valproate/lithium combination in ALS patients by M.-C. Boll, M. Alcaraz-Zubeldia, C. Rios, D. González-Esquivel, S. Montes

“…Conclusions: Combined VPA-Li treatment associated with slower ALS progression and better secondary outcomes. This dual treatment overcame the futility threshold and merits further investigation in ALS. …”
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A phase 2, double-blind, placebo-controlled trial of a valproate/lithium combination in ALS patients by M.-C. Boll, M. Alcaraz-Zubeldia, C. Rios, D. González-Esquivel, S. Montes

“…Conclusions: Combined VPA-Li treatment associated with slower ALS progression and better secondary outcomes. This dual treatment overcame the futility threshold and merits further investigation in ALS. …”
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Hsp90α promotes lipogenesis by stabilizing FASN and promoting FASN transcription via LXRα in hepatocellular carcinoma by Zihao Deng, Lixia Liu, Guantai Xie, Zhenming Zheng, Jieyou Li, Wenchong Tan, Yaotang Deng, Jinxin Zhang, Manfeng Liang, Yingxia Wu, Zhifeng Zhou, Yan Li, Yukui Chen, Yaling Huang, Hairou Su, Guibing Wu, Xiongjie Shi, Shengpei Cen, Yandan Liao, Yilin Liu, Fei Zou, Xuemei Chen

“…Excessive lipid accumulation promotes the occurrence and progression of hepatocellular carcinoma (HCC), accompanied by high levels of fatty acid synthetase (FASN) and more active lipogenesis. …”
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Epidemiological characteristics of elderly osteoporosis fractures and their association with air pollutants: a multi-center study in Hebei Province by Guangzhao Hou, Qian Xiao, Zhipeng Ye, Shihang Liu, Shuai Zhou, Yan Wang, Wenjing Li, Yingze Zhang, Hongzhi Lv

“…The number of hospitalized patients increased progressively from 2019 to 2022. The Distribution Lag Nonlinear Model (DLNM) showed that the cumulative lagged effects of PM2.5 and PM10 on the number of hospitalized elderly osteoporosis fracture patients exhibited a bimodal distribution, with the Relative Risk (RR) reaching its peak at a 1-day lag (PM2.5: RR = 1.032, 95% CI: 1.019, 1.045; PM10: RR = 1.022, 95% CI: 1.014, 1.029). …”
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From skyscrapers to sky savers: how New York City’s Local Law 97 advances climate resilience and public health by Ethan Chervonski, Ethan Chervonski, Marisa A. Guerrero, William N. Rom, William N. Rom

“…Local Law 97 (LL97) is the latest in NYC’s long trajectory of climate action initiatives, setting progressively stringent caps on greenhouse gas (GHG) emissions from large buildings greater than 25,000 square feet. …”
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