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USP39 phase separates into the nucleolus and drives lung adenocarcinoma progression by promoting GLI1 expression
Published 2025-01-01“…The effects of USP39 depletion on tumor progression were tested using doxycycline-inducible USP39 knockdown and rescue lung adenocarcinoma cells both in vitro and in vivo by performing MTT, colony formation, EdU staining, transwell and tumor xenograft model experiments. …”
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Epithelial cell diversity and immune remodeling in bladder cancer progression: insights from single-cell transcriptomics
Published 2025-01-01“…Abstract Background The progression of bladder cancer (BC) from non-muscle-invasive bladder cancer (NMIBC) to muscle-invasive bladder cancer (MIBC) significantly increases disease severity. …”
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MicroRNA-877-5p Inhibits Cell Progression by Targeting FOXM1 in Lung Cancer
Published 2022-01-01“…Taken together, miR-877-5p inhibited cell progression by directly targeting FOXM1, which may provide potential biomarkers for targeted therapy of NSCLC.…”
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Research progress and prospect of intelligent prediction and disaster risk assessment of open-pit mining surface deformation
Published 2024-12-01“…This paper summarizes the research progress of surface deformation hazards in open-pit mines from three aspects: intelligent perception, intelligent prediction and disaster risk evaluation of surface deformation. …”
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A Case of Stage I Vulvar Squamous Cell Carcinoma with Early Relapse and Rapid Disease Progression
Published 2019-01-01“…We report a case of a woman who experienced a rapid, chemorefractory tumor progression after surgery for stage IB vulvar SCC.…”
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Predicting the Progress of Tuberculosis by Inflammatory Response-Related Genes Based on Multiple Machine Learning Comprehensive Analysis
Published 2023-01-01“…Our research has identified key inflammatory response-related genes that are characteristic of LTBI progression to ATB and hsa-miR-3163 as a significant node in the molecular mechanism of this progression. …”
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USP14 inhibition by degrasyn induces YAP1 degradation and suppresses the progression of radioresistant esophageal cancer
Published 2025-02-01“…Here, we identified a potential inhibitor of USP14, Degrasyn (DGS), and investigated its regulatory effects on ESCA radioresistance and progression. We found that DGS had marked antiproliferative effects in radiosensitive ESCA cell lines. …”
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Andrographolide suppresses cervical cancer progression by targeting angiogenesis and inducing apoptosis in a CAM-PDX model
Published 2025-02-01“…This study explores the therapeutic potential of andrographolide (AND), a bioactive compound derived from Andrographis paniculata, in mitigating cervical cancer progression using the chick embryo chorioallantoic membrane patient-derived xenograft (CAM-PDX) model. …”
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Diabetic Retinopathy Is a Predictor of Progression of Diabetic Kidney Disease: A Systematic Review and Meta-Analysis
Published 2022-01-01“…This systematic review and meta-analysis aimed to assess the predictive value of diabetic retinopathy (DR) for progression of diabetic kidney disease (DKD). Methods. …”
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Multi-scale analysis of the progressive failure behaviour of 2.5D woven SiC/SiC composites under compression
Published 2025-01-01“…To simulate the damage evolution process of specimens, a multi-scale finite element model representing the meso-scale structure of 2.5D SiC/SiC composites was developed, in which the proposed progressive damage method emphasising on matrix damage was adopted. …”
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Progressive subchondral bone cyst formation following autologous chondrocyte implantation with all-suture anchors: a Case Report with histological evaluation
Published 2025-02-01“…However, the etiology and progression of SBCs following ACI remain poorly understood. …”
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Atypical Lipomatous Tumor/Well-Differentiated Liposarcoma Developed in a Patient with Progressive Muscular Dystrophy: A Case Report and Review of the Literature
Published 2017-01-01“…Muscular dystrophy (MD) is characterized by progressive muscle atrophy and its replacement by adipose and fibrous tissue. …”
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Acute Progressive Visual Loss in a Case of Acute Myeloid Leukemia: Challenges in the Utility of Molecular Tests in Early Diagnose of Cytomegalovirus Retinitis
Published 2018-01-01“…Herein, we report a 12-year-old boy with acute myeloid leukemia complicated by rapid progressive visual loss during relapse of leukemia. …”
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Outcome of 177Lu-DOTATATE Peptide Receptor Radionuclide Therapy in Progressive Metastatic Neuroendocrine Tumors from a Tertiary Care Center
Published 2024-12-01“…The benefit of 177Lu-DOTATATE PRRT in patients with progressive metastatic NET was analyzed and survival in multi-organ involvement. …”
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