Liver lobes and cirrhosis: Diagnostic insights from lobar ratios by Kriti Pandey, Debabrata Dash, Raj Kumar Koiri

“…Alcohol, viral hepatitis, and non-alcoholic fatty liver disease are the most common cause of cirrhosis. Cirrhosis progresses from the compensated stage to the decompensated stage. …”
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The triterpenoids-enriched extracts from Antrodia cinnamomea mycelia attenuate alcohol-induced chronic liver injury via suppression lipid accumulation in C57BL/6 mice by Yange Liu, Ronglong Chen, Lanzhou Li, Ruitao Dong, Hui Yin, Yawen Wang, Anhui Yang, Jianbin Wang, Changtian Li, Di Wang

“…Combining with the pathological observations, ACT displayed an anti-steatosis effects to restrain the progress of ALD. Based on proteomic analysis and enzyme-linked immunosorbent assay, ACT had been confirmed to regulate the levels of lipid biogeneration-related factors and depressed the over-accumulation of hepatic reactive oxygen species. …”
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Design and Optimization of the Circulatory Cell-Driven Drug Delivery Platform by Pengyu Gao, Dan Zou, Ansha Zhao, Ping Yang

“…Although nanoparticle-based drug delivery systems have made great progress in extending circulation time, improving durability, and controlling drug release, the targeting efficiency remains low. …”
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NADH Reductive Stress and Its Correlation with Disease Severity in Leigh Syndrome: A Pilot Study Using Patient Fibroblasts and a Mouse Model by Tamaki Ishima, Natsuka Kimura, Mizuki Kobayashi, Chika Watanabe, Eriko F. Jimbo, Ryosuke Kobayashi, Takuro Horii, Izuho Hatada, Kei Murayama, Akira Ohtake, Ryozo Nagai, Hitoshi Osaka, Kenichi Aizawa

“…This precise method for NADH measurement is expected to outperform conventional assays, such as those for lactate, providing a simpler and more reliable means of assessing disease progression.…”
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The Effect of Physical Activity on Alzheimer’s Disease - Systematic Review by Julia Lachowska, Karolina Senior, Jerzy Smandek, Maja Mielczarek, Paulina Sroczyńska, Jan Sroczyński

“…Despite the absence of a cure, early intervention during the prodromal phase can slow the progression of AD, highlighting the importance of identifying modifiable risk and protective factors. …”
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Factors Related to The Family Latrine Use Coverage in Sabilambo Village Kolaka District by Fitri Yanti, Erwin Azizi Jayadipraja, Maryam Kandari, Rahmawati Rahmawati, Munawir Amasyah

“… Background:Among the seven sub-districts within the Kolaka Health Center Working Area, Sabilambo Village exhibited the lowest progress in family latrine ownership. Objectives:This study aims to identify the factors associated with the coverage of family latrine use in Sabilambo Village, Kolaka Regency. …”
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Regulation of fibronectin and collagens type I, III and VI by TNF-α, TGF-β, IL-13, and tofacitinib by Frederik S. Gillesberg, Martin Pehrsson, Anne-Christine Bay-Jensen, Peder Frederiksen, Morten Karsdal, Bent W. Deleuran, Tue W. Kragstrup, Satoshi Kubo, Yoshiya Tanaka, Joachim H. Mortensen

“…We show that 12-day fibroblast culture with TNF-α or IL-13 induces fibrogenesis, marked by progressively increasing type III and VI collagen formation, and that TGF-β1 co-stimulation amplifies these effects. …”
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Identification of Repellent and Insecticidal Constituents from Artemisia mongolica Essential Oil against Lasioderma serricorne by Chunxue You, Shanshan Guo, Wenjuan Zhang, Kai Yang, Zhufeng Geng, Shushan Du, Chengfang Wang, Zhiwei Deng

“…With a further isolation process, five constituents obtained from the essential oil were identified as eucalyptol, verbenol, 4-terpineol, camphor, and α-terpineol. In the progress of assay, it showed that L. serricorne adults had different sensitivities to the crude essential oil and isolated constituents. 4-Terpineol exhibited strongest contact activity against L. serricorne, showing the LD50 value of 8.62 μg/adult. …”
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Prehabilitation during neoadjuvant therapy in patients with cancer of the upper gastrointestinal tract and rectum—the study protocol by Irina Chmelova, Irina Chmelova, Dalibor Pastucha, Dalibor Pastucha, Tomas Hudecek, Zdenek Guran, Zdenek Guran, Sona Ciecotkova, Lubomír Martínek, Jana Zubikova, Alena Matlova, Jakub Dolezel, Dana Salounova, Jakub Chmelo

“…The training consists of progressively dosed walking and strength exercises for selected muscle groups. …”
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Expression of VEGF-A, Otx Homeobox and p53 Family Genes in Proliferative Vitreoretinopathy by Claudio Azzolini, Ilaria Stefania Pagani, Cristina Pirrone, Davide Borroni, Simone Donati, Muna Al Oum, Diana Pigni, Anna Maria Chiaravalli, Riccardo Vinciguerra, Francesca Simonelli, Giovanni Porta

“…We individuated two possible pathways (VEGF-A, Otx2, p53, p63 and Otx1 and Otx3) involved in PVR progression that could influence in different manners the course of the pathology. …”
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Tissue sodium in patients with rheumatoid arthritis: a novel potential driver of hypertension in autoimmunity by Carolina Ramirez-Becerra, Annette M. Oeser, Michael Pridmore, Rachelle Crescenzi, Jens M. Titze, C. Michael Stein, Michelle J. Ormseth

“…Tissue sodium may contribute to development and progression of hypertension through immune cell activation. …”
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Multidisciplinary approach to functional somatic syndromes: study protocol for a population-based prospective cohort study by Hamidreza Roohafza, Harold Snieder, Fatemeh Hadizadeh, Peyman Adibi, Alireza Ani, Ahmad Vaez

“…Human DNA genotyping, microbial amplicon sequencing and urine analysis is under progress for genomics, microbiota and metabolomics profiling, respectively. …”
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Collaborative management of severe periodontal-endodontic lesion with intense lip sucking: a case report by Yanfei Sun, Xiaofang Zhao, Mingchao Wang, Xiangkun Sun, Kunzhou Mei, Yameng Zhang, Yanwen Cui, Fang Yang

“…Timely identification and intervention in managing oral habits can halt disease progression and ensure favorable outcomes. Additionally, this report offers treatment guidelines and recommendations for severe dental diseases caused by detrimental oral habits.…”
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Biodiversity futures: digital approaches to knowledge and conservation of biological diversity by H. Freitas, H. Freitas, A. C. Gouveia, A. C. Gouveia

“…Global commitments, such as the Aichi Biodiversity Targets and the United Nations (UN) Sustainable Development Goals, are not delivering consistent results, and progress on conservation has been frustratingly slow. …”
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Numerical Simulation of Empty-Hole Effect during Parallel-Hole Cutting under Different In Situ Stress Conditions by Zhengyu Wu, Dayou Luo, Feng Chen, Wulin Huang

“…With the progress of deep mining in mine exploitation, the effect of the in situ stress field plays a more and more significant and crucial role in rock blasting. …”
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Mast Cells Positive to Tryptase and c-Kit Receptor Expressing Cells Correlates with Angiogenesis in Gastric Cancer Patients Surgically Treated by Michele Ammendola, Rosario Sacco, Giuseppe Sammarco, Giuseppe Donato, Valeria Zuccalà, Roberto Romano, Maria Luposella, Rosa Patruno, Carlo Vallicelli, Giorgio Maria Verdecchia, Davide Cavaliere, Severino Montemurro, Girolamo Ranieri

“…Angiogenesis is a complex process involved in both growth and progression of several human and animal tumours. Tryptase is a serin protease stored in mast cells granules, which plays a role in tumour angiogenesis. …”
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Impact of Cataract Surgery on the Psychological State of the Elderly by Bárbara Nuria Suárez Rodríguez, Leonor Rosario Díaz Alfonso, Daniel Martínez Ojeda, Yutsimí Elia Fojaco Colina, Aleima Rodríguez Carvajal

“…<strong>Background: </strong>Progressively aging populations are one of the most distinctive demographic phenomena of the last decades. …”
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Targeting natural antioxidant polyphenols to protect neuroinflammation and neurodegenerative diseases: a comprehensive review by Maroua Jalouli, Md Ataur Rahman, Partha Biswas, Hasanur Rahman, Abdel Halim Harrath, In-Seon Lee, In-Seon Lee, Sojin Kang, Jinwon Choi, Moon Nyeo Park, Bonglee Kim, Bonglee Kim

“…These compounds possess diverse neuroprotective capabilities, including antioxidant, anti-inflammatory, and anti-amyloid properties, which contribute to mitigating the progression of neurodegenerative conditions such as Alzheimer’s Disease (AD), Parkinson’s Disease (PD), Dementia, Multiple Sclerosis (MS), Stroke, and Huntington’s Disease (HD). …”
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Central Precocious Puberty and Response to GnRHa Therapy in Children with Cerebral Palsy and Moderate to Severe Motor Impairment: Data from a Longitudinal, Case-Control, Multicentr... by Patrizia Bruzzi, Maria Francesca Messina, Alessandra Bartoli, Barbara Predieri, Laura Lucaccioni, Simona Filomena Madeo, Alberto Verrotti, Filippo De Luca, Lorenzo Iughetti

“…Diagnosis of CPP could be partially mislead in CP due to growth failure that got worse during follow-up despite therapy. CPP in CP seems to progress rapidly along time supporting the hypothesis of a more intense activation of hypothalamic-pituitary-gonadal-axis in these patients.…”
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Sex and authorship in global cancer research by Deborah Mukherji, Ophira Ginsburg, Grant Lewison, Richard Sullivan, Verna Vanderpuye, Winnie K W So, Miriam Mutebi, Nazik Hammad, Julie Torode, Erica Liebermann

“…The top performing countries in terms female/male parity for first or last authorship were in Eastern and Southern Europe as well as Latin American countries.From 2009 to 2019, the highest proportion of females as first and last authors were from low-income and middle-income countries in Latin America and Eastern Europe.Females were more likely to publish in lower impact journals and were less likely to be cited compared to males.Conclusions Globally, progress in female’s authorship in oncology research has been uneven. …”
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