Gamma-Tocotrienol Stimulates the Proliferation, Differentiation, and Mineralization in Osteoblastic MC3T3-E1 Cells by Weili Xu, Pan He, Shenghua He, Pengju Cui, Yaqing Mi, Yang Yang, Yang Li, Shaobo Zhou

“…Our results showed that γ-tocotrienol (2–8 μmol/L) significantly improved the cell proliferation (p<0.05), but it did not affect cell cycle progression. γ-Tocotrienol significantly increased alkaline phosphatase (ALP) activity (p<0.05), secretion levels of osteocalcin (OC) and osteonectin (ON), and mRNA levels of collagen type I (Col I) of MC3T3-E1 cells. …”
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Motion detection for patient safety in CT scanner by Zaynab Boujelb, Ahmed Idrissi, Achraf Benba, El Mahjoub Chakir

“…In the last decades, recent progress in IoT and embedded devices has enabled the conception of cost-effective real-time systems. …”
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Gene Expression Profiling of IL-17A-Treated Synovial Fibroblasts from the Human Temporomandibular Joint by Toshio Hattori, Naomi Ogura, Miwa Akutsu, Mutsumi Kawashima, Suguru Watanabe, Ko Ito, Toshirou Kondoh

“…These results suggest that IL-17A is associated with the inflammatory progression of TMD.…”
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A Novel Bacteriophage with the Potential to Inhibit <i>Fusobacterium nucleatum</i>-Induced Proliferation of Colorectal Cancer Cells by Ho Yin Pekkle Lam, Meng-Jiun Lai, Pin-Chun Wang, Wen-Jui Wu, Li-Kuang Chen, Hsiang-Wei Fan, Chun-Chieh Tseng, Shih-Yi Peng, Kai-Chih Chang

“…Background: Increasing evidence shows that <i>Fusobacterium nucleatum</i> (<i>F. nucleatum</i>) largely affects colorectal cancer (CRC) growth and progression; therefore, the inhibition of intratumoral <i>F. nucleatum</i> may be one realistic approach to combat CRC. …”
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A Case Report of High-Grade Endometrial Stromal Sarcoma: A Rare Cause of Abnormal Uterine Bleeding in a Young Woman by Nuntasiri Eamudomkarn, Yuwadee Itarat, Pilaiwan Kleebkaow, Chumnan Kietpeerakool

“…The patient experienced rapid progression of the disease while receiving adjuvant treatment and succumbed eight months after the operation. …”
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Molecular Modulation of Fetal Liver Hematopoietic Stem Cell Mobilization into Fetal Bone Marrow in Mice by Huihong Zeng, Jiaoqi Cheng, Ying Fan, Yingying Luan, Juan Yang, Feixuan Wang, Shuo Yang, Lijian Shao

“…We reviewed current progress about the effects of fetal liver niche, chemokine, cytokine, and signaling pathways on HSC self-renewal, proliferation, and expansion. …”
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Altered Expressions of miR-1238-3p, miR-494, miR-6069, and miR-139-3p in the Formation of Chronic Brucellosis by Ferah Budak, Salih Haldun Bal, Gulcin Tezcan, Halis Akalın, Guher Goral, Haluk Barbaros Oral

“…The differentially expressed miRNAs and their predicted target genes involved in endocytosis, regulation of actin cytoskeleton, MAPK signaling pathway, and cytokine-cytokine receptor interaction and its chemokine signaling pathway indicate their potential roles in chronic brucellosis and its progression. It is the first study of miRNA expression analysis of human PBMC to clarify the mechanism of inveteracy in brucellosis.…”
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HDAC1-3 inhibition triggers NEDD4-mediated CCR2 downregulation and attenuates immunosuppression in myeloid-derived suppressor cells by Zhiqi Xie, Jinjin Shao, Zeren Shen, Zhichao Ye, Yoshiaki Okada, Daisuke Okuzaki, Naoki Okada, Masashi Tachibana

“…Abstract Myeloid-derived suppressor cells (MDSCs) play a critical role in cancer progression and resistance, thus representing promising targets for immunotherapy. …”
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Developments and clinical experiences in collagenase chemonucleolysis for lumbar disc herniation: a narrative review by Hao Zhang, Chi Zhang, Lin Li, Ming-liang Hu, Jian-ning Zhao, Zhang Zheng, Wen-feng Ding

“…Key advancements include the transition from single-agent to combination therapies, exploration of diverse injection routes, and the progression from C-arm fluoroscopy to multi-slice CT guidance. …”
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An Evolutionary Federated Learning Approach to Diagnose Alzheimer’s Disease Under Uncertainty by Nanziba Basnin, Tanjim Mahmud, Raihan Ul Islam, Karl Andersson

“…Early diagnosis of AD is imperative to enable timely interventions that can slow the progression of the disease. This research tackles the complexity and uncertainty of AD by employing a multimodal approach that integrates medical imaging and demographic data. …”
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Evaluation of health-related quality of life among patients with chronic obstructive pulmonary disease at District Headquarter Hospital haripur, Pakistan by Mehwish Fayaz, Shahbaz Ahmad Zakki, Ijaz Ul Haq, Muhammad Afzal, Mudassar Latif, Ehtisham Altaf

“…Conclusion: The impairment of quality of life is a notable issue among patients diagnosed with COPD, and it tends to worsen as the disease progresses in severity. The need of the hour is to promote awareness about COPD in the community and sensitize healthcare professionals towards its effects on HRQoL.…”
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LDAViewer: An Automatic Language-Agnostic System for Discovering State-of-the-Art Topics in Research Using Topic Modeling, Bidirectional Encoder Representations From Transformers,... by Timothy Dillan, Dhomas Hatta Fudholi

“…Advancements in knowledge are pivotal to academic progress, necessitating efficient methods for discovering the state-of-the-art in various fields. …”
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Multiscale guided attention network for optic disc segmentation of retinal images by A Z M Ehtesham Chowdhury, Andrew Mehnert, Graham Mann, William H. Morgan, Ferdous Sohel

“…Optic disc (OD) segmentation from retinal images is crucial for diagnosing, assessing, and tracking the progression of several sight-threatening diseases. This paper presents a deep machine-learning method for semantically segmenting OD from retinal images. …”
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Effects of long-term adapted physical training on functional capacity and quality of life in older adults with Parkinson's disease by Oussama Gaied Chortane, Elmoetez Magtouf, Wael Maktouf, Sabri Gaied Chortane

“…Although physical activity is considered a therapeutic treatment to slow the progression of the disease, it is considered to be an effective non-pharmacological adjuvant to medication to improve the symptom management.MethodsThe training program was offered for all the participants (N = 50) in three non-consecutive sessions per week for 60 minutes and a total duration of 12 to 16 months. …”
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Qufeng epimedium decoction alleviates rheumatoid arthritis through CYLD-antagonized NF-kB activation by deubiquitinating Sirt1 by Zhiming Wu, Peng Zhang, Wenyan Huang, Yifen Zhou, Zhengliu Cao, Chunhong Wu

“…Conclusion: Our findings indicate that Qufeng epimedium decoction suppresses FLSs pyroptosis and RA progression via CYLD-mediated Sirt1 deubiquitination and deactivation of the NF-kB /GSDMD signaling pathway. …”
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Advances in growth factor-containing 3D printed scaffolds in orthopedics by Longwen Zhan, Yigui Zhou, Ruitang Liu, Ruilong Sun, Yunfei Li, Yongzheng Tian, Bo Fan

“…This paper aims to summarize the research progress of 3D printed scaffolds containing growth factors in orthopedics in recent years and summarize the use of different growth factors in 3D scaffolds, including bone morphogenetic proteins, platelet-derived growth factors, transforming growth factors, vascular endothelial growth factors, etc. …”
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Dynamic non-coding RNA biomarker reveals lung injury and repair induced by polystyrene nanoplastics by Sheng Yang, Yiling Ge, Tianyi Zhang, Lihong Yin, Yuepu Pu, Zaozao Chen, Geyu Liang

“…Moreover, temporal profiling highlighted distinct sets of ncRNAs as early and progression-associated biomarkers of PS-NP-induced lung injury. …”
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IL1RN and KRT13 Expression in Bladder Cancer: Association with Pathologic Characteristics and Smoking Status by Thomas S. Worst, Verena Reiner, Ute Gabriel, Christel Weiß, Philipp Erben, Thomas Martini, Christian Bolenz

“…Tobacco smoking may enhance the loss of IL1RN, indicating an overweight of proinflammatory mediators involved in UCB progression. Further validation of the influence of smoking on IL1RN expression is warranted.…”
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Integrated analysis of dermatomyositis reveals heterogeneous immune infiltration and interstitial lung disease-associated endotype by Xinzhi Xu, Tianwen Qiu, Kexin Sun, Xue Han, Junxia Huang, Xiuyuan Wang, Jianchao Ge, Ji Yang

“…Two chemokines, CXCL10 and CXCL11, were identified as highly associated with immune infiltration and DM progression. Conclusions Our data suggest that serum CXCL10 and CXCL11 reflect the inflammatory burden of DM. …”
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Enhancing Social Media User&#x2019;s Trust: A Comprehensive Framework for Detecting Malicious Profiles Using Multi-Dimensional Analytics by Sailaja Terumalasetti, S. R. Reeja

“…Traditional methods for distinguishing these accounts archetypally depend on an inadequate set of features, which hampers their effectiveness in contrast to the progressively sophisticated maneuvers employed by malicious users. …”
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