A machine learning based algorithm accurately stages liver disease by quantification of arteries by Zhengxin Li, Xin Sun, Zhimin Zhao, Qiang Yang, Yayun Ren, Xiao Teng, Dean C. S. Tai, Ian R. Wanless, Jörn M. Schattenberg, Chenghai Liu

“…AD was counted using qVessel (previously trained on manually labeled vessels by stained slides (CD34/a-SMA/CK19) and developed by a decision tree algorithm). As liver fibrosis progressed from F1 to F4, we observed that both AD and CPA gradually increases among the three etiologies (P < 0.05). …”
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Augmented prediction of vertebral collapse after osteoporotic vertebral compression fractures through parameter-efficient fine-tuning of biomedical foundation models by Sibeen Kim, Inkyeong Kim, Woon Tak Yuh, Sangmin Han, Choonghyo Kim, Young San Ko, Wonwoo Cho, Sung Bae Park

“…This study aimed to develop a predictive model leveraging deep neural networks to predict VC progression after OVCF using magnetic resonance imaging (MRI) and clinical data. …”
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Drug delivery systems for oral cancer treatment: A patent perspective by Mohamed Hassan Dehghan, Abrar Abdul Malik Siddiqui

“…Major risk factors for oral cancer include tobacco and alcohol use, HPV infections, poor nutrition, and genetic susceptibility. The disease progresses through multiple genetic and epigenetic alterations involving tumor suppressors like p53, p16, and FHIT, along with oncogenes like EGFR, c-yc, K-ras, int-2, PRAD-1, and bcl leading to the development of premalignant lesions and subsequent tumors. …”
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Nomogram models for predicting outcomes in thyroid cancer patients with distant metastasis receiving 131iodine therapy by Shui Jin, Xuemei Ye, Ting Ye, Xinyu Chen, Jianfeng Ji, Jinyu Wang, Xin Zhu, Xiaochun Mao, Takahiro Higuchi, Heqing Yi

“…Univariate and multivariate Cox regression analyses were used to identify independent predictors for overall survival (OS) and progression-free survival (PFS). Nomograms were developed based on these predictors, and Kaplan-Meier curves were constructed for validation. …”
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Exploring the prognostic significance of lactate-mitochondria-related genes in prostate cancer by Yuan Wang, Ronghui Chen, Feng-Le Jiang, Feng-Le Jiang, Xin Jiang, Xin Jiang, Yuehong Zhou, Yingying Zhou, Xinyi Hong, Chaoying Lin, Wei-Jia Wang, Wei-Jia Wang, Sufang Qiu

“…Metabolic reprogramming, particularly involving lactate and mitochondria, plays a key role in PCa progression, but studies linking these factors to prognosis are limited. …”
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Opioidergic tuning of social attachment: reciprocal relationship between social deprivation and opioid abuse by Julia A. Galiza Soares, Samantha N. Sutley-Koury, Matthew B. Pomrenze, Matthew B. Pomrenze, Jason M. Tucciarone

“…Social factors also appear to impact susceptibility and progression of opioid dependence. In particular, increasing evidence suggests that poor early social bond formation and social environments may increase the risk of opioid abuse later in life. …”
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A comprehensive overview of selective and novel fibroblast growth factor receptor inhibitors as a potential anticancer modality by Jain Nem Kumar, Tailang Mukul, Thangavel Neelaveni, Makeen Hafiz A., Albratty Mohammed, Najmi Asim, Alhazmi Hassan Ahmad, Zoghebi Khalid, Alagusundaram Muthumanickam, Jain Hemant Kumar, Chandrasekaran Balakumar

“…This review highlights the current clinical progress concerning the safety and efficacy of all the approved FGFR-TKIs (tyrosine kinase inhibitors) and their ongoing investigations in clinical trials for other oncogenic FGFR-driven malignancies.…”
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Genome-Wide Approach Identifies Natural Large-Fragment Deletion in ASFV Strains Circulating in Italy During 2023 by Claudia Torresi, Roberta Biccheri, Cesare Cammà, Carmina Gallardo, Maurilia Marcacci, Simona Zoppi, Barbara Secondini, Caterina Riverso, Alejandro Soler, Cristina Casciari, Michela Pela, Elisabetta Rossi, Claudia Pellegrini, Carmen Iscaro, Francesco Feliziani, Monica Giammarioli

“…In vivo characterization of the deleted strain 22489.4_2312/RC/2023 revealed identical disease progression to the wild-type strain, with severe ASF symptoms in inoculated pigs. …”
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A Review of Supply Chain Resilience: A Network Modeling Perspective by Chuhan Ma, Lei Zhang, Liang You, Wenjie Tian

“…This paper adopts a network modeling perspective to systematically review the theoretical foundations and research progress in supply chain resilience, focusing on the application of network modeling methods. …”
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Comprehensive bioinformatics analysis reveals novel potential biomarkers associated with aging and mitochondria in osteoporosis by Ke Bi, Yuxi Chen, Yuhang Hu, Song Li, Weiming Li, Zhange Yu, Lei Yu

“…Aging and mitochondrial dysfunction are involved in the onset and progression of OP, but the specific mechanisms have not been elucidated. …”
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Paradoxical Association of Postoperative Plasma Sphingosine-1-Phosphate with Breast Cancer Aggressiveness and Chemotherapy by Rajesh Ramanathan, Ali Raza, Jamie Sturgill, Debra Lyon, Jessica Young, Nitai C. Hait, Kazuaki Takabe

“…Sphingosine-1-phosphate (S1P) is a bioactive lipid mediator that has been shown to serve an important regulatory function in breast cancer progression. This study analyzes plasma S1P levels in breast cancer patients undergoing adjuvant therapy as compared to healthy control volunteers. 452 plasma S1P samples among 158 breast cancer patients, along with 20 healthy control volunteers, were analyzed. …”
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Anti-inflammatory Property of Galectin-1 in a Murine Model of Allergic Airway Inflammation by Yunxiang Lv, Mengyuan Dai, Muzi Wang, Fangfang Chen, Rongyu Liu

“…We explored the pharmacological effects of Gal-1 on the progression of allergic airway inflammation and investigated the underlying mechanism. …”
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Electroconvulsive Therapy in a Renal Transplantation Patient: A Rare Combination of Disease and Treatment by Giovanni Malaty, Kerilyn Godbe, Mehdi Elmouchtari, Gurjot Malhi, Justin White, Azziza Bankole, Tracey Criss

“…Electroconvulsive therapy was subsequently initiated and was well-tolerated. Treatments progressively alleviated his depressive and psychotic symptoms and did not adversely affect the function of his transplanted kidney, which was closely monitored throughout the treatment process. …”
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Ultrasonographic evaluation of the thorax in dogs with tick paralysis by Erdem Gülersoy, Canberk Balıkçı, İsmail Günal, Adem Şahan, Esma Kısmet

“… Tick paralysis is a rapidly progressing motor paralysis caused by a neurotoxin in the saliva of certain tick species. …”
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Bioceramic Surface Topography Regulating Immune Osteogenesis by Jianxin Hao, Lin Du, Yuening He, Chengtie Wu

“…After the implantation of bioceramics, innate immune response that occurs at the interface of materials can deeply influence the subsequent inflammation and bone regeneration progress. Therefore, the exploration and regulation of immune response of the bioceramic interface will be beneficial to promote the bone regeneration effects. …”
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Experimental study on the collapse behavior of cavitation bubbles under low ambient pressure conditions by Tong Qu, Jing Luo, Weilin Xu, Jie Li, Guihua Fu, Yueqing Ma, Zhuoqi Zhao

“…Correspondingly, the proportion of shockwave energy relative to the bubble’s total mechanical energy also decreases progressively. Based on the behavior of bubbles under low ambient pressure conditions described above, it was found that as ambient pressure decreases, the maximum microjet velocity during cavitation bubble collapse in proximity to rigid walls gradually decreases at a constant bubble-wall distance. …”
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The Silent Threat of Human Metapneumovirus: Clinical Challenges and Diagnostic Insights from a Severe Pneumonia Case by Rubens Carmo Costa-Filho, Felipe Saddy, João Luiz Ferreira Costa, Leandro Reis Tavares, Hugo Caire Castro Faria Neto

“…Results: The patient presented with respiratory symptoms that progressed to hypoxia, productive cough, and fatigue, requiring hospitalization. …”
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Hubungan antara Profil Lipid dengan Kejadian Retinopati Diabetika pada Pasien Diabetes Melitus Tipe 2 di Fasilitas Kesehatan Tingkat Pertama Klinik Tanjung Purwokerto by Ika Murti Harini, Muhamad Rifqy Setyanto, Nur Signa Aini Gumilas, Dwi Arini Ernawati

“…One of the risk factors for the development and progression of diabetic retinopathy is lipid profile levels in DM patients. …”
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Temozolomide as Second or Third Line Treatment of Patients with Neuroendocrine Carcinomas by Ingrid H. Olsen, Jens B. Sørensen, Birgitte Federspiel, Andreas Kjaer, Carsten P. Hansen, Ulrich Knigge, Seppo W. Langer

“…Sixteen patients were evaluable for response: Six achieved stable disease and ten progressed. The median survival for the 28 patients was 3.5 months. …”
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A new immunofluorescence determination of Parkinson's disease biomarkers using silver nanoparticles by Chao Qin, Jun Xia, Yong Wen, Jun Wang, Chen Zhong

“…Prompt identification and tracking of PD progression are essential for prompt intervention and efficient PD care. …”
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