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13341
Lower Hemoglobin Concentration Is Associated with Retinal Ischemia and the Severity of Diabetic Retinopathy in Type 2 Diabetes
Published 2016-01-01“…Low hemoglobin levels may have a key role in the development and progression of DR.…”
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13342
Treatment compliance of liver cirrhosis patients
Published 2018-08-01“…Patients with LC of the Child-Pugh class B had highest compliance level (97.00±7.31), while those with Child-Pugh Class C - the lowest (80.89±11.73). Progression of encephalopathy exerts negative impact on treatment compliance. …”
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13343
Unraveling the function of TSC1-TSC2 complex: implications for stem cell fate
Published 2025-02-01“…For over 20 years, significant progress has linked TSC1 or TSC2 gene mutations in stem cells to tuberous sclerosis complex symptoms. …”
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13344
GLP1R boosts survival, migration and invasion of endometrial cancer cells and protects against ferroptotic cell death
Published 2024-12-01“…Moreover, GLP1R lowered intracellular ROS level and expression of SLC7A11, and FTH1, but mitigated GPX4 expression in AN3CA cells.Conclusion In a word, GLP1R was up-regulated in EC and its up-regulation facilitated the proliferative and metastatic potentials, and protected cells from ferroptosis, thereby accelerating EC progression. These data emphasised the potency of GLP1R as a therapeutic agent against EC.…”
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13345
SGLT2i and GLP-1RA in Cardiometabolic and Renal Diseases: From Glycemic Control to Adipose Tissue Inflammation and Senescence
Published 2021-01-01“…Moreover, other frequent comorbidities in long-standing diabetic patients are chronic complications such as diabetic kidney disease, whose progression can be slowed by SGLT2i and/or GLP-1RA. …”
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13346
Temporary Fecal Diversion in the Management of Colorectal and Perianal Crohn’s Disease
Published 2015-01-01“…The response to temporary fecal diversion was complete remission in 4/29 (13.8%), partial remission in 12/29 (41.4%), no change in 7/29 (24.1%), and progress in 6/29 (20.7%). Stoma reversal was performed in 19 out of 25 patients (76%) available for follow-up. …”
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13347
Bridge Construction Impacts the Adjacent Channel Morphology and Turbidity: A Study on a Dying Distributary of River Padma
Published 2024-12-01“…The construction of a new highway bridge over the Jalangi River commenced a few years ago, experiencing occasional halts and progressing at a notably sluggish pace. However, in 2022, the construction gained momentum and was completed in 2023. …”
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13348
Distinct MicroRNA Subcellular Size and Expression Patterns in Human Cancer Cells
Published 2012-01-01“…To determine the relationship between miRNA sub-cellular distribution and cancer progression, we used microarray analysis to examine the miRNA expression levels in nucleus and cytoplasm of three human cell lines, one normal breast cell line and two breast cancer cell lines. …”
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13349
Continuous monitoring of temporal skills during long-term in-home training by cochlear implant users
Published 2025-02-01“…Fifty cochlear implant users and 45 normally hearing volunteers participated in repeated testing sessions.Logistic regression with restricted cubic splines was used to analyse temporal changes in musical perception, offering insights into score distributions and progression over time. Results revealed significant differences in scores, with volunteers outperforming cochlear implant users. …”
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13350
Spectral Domain Optical Coherence Tomographic Findings of Bietti Crystalline Dystrophy
Published 2014-01-01“…SD-OCT shows the disease progression in retinal and choroidal layers delicately in eyes with BCD and expands our knowledge about the ongoing disease process.…”
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13351
Analysis of Falling Block Characteristics in Salt Caverns Energy Storage Space
Published 2025-01-01“…However, in actual operation, multi-layer salt cavities are prone to collapse of interlayer and bending of pipes, seriously affecting the progress, quality, and safety of the entire energy storage space construction. …”
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13352
Females in higher education and leadership: insights from a multi-method approach
Published 2025-01-01“…Through descriptive analyses, surveys, and interviews, the research assesses female representation at various academic levels and identifies key factors influencing career progression. The findings reveal that gender parity in enrolment has been achieved, with Latin America & Caribbean leading, followed by Europe and Central Asia. …”
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13353
Graph Convolutional Networks for multi-modal robotic martial arts leg pose recognition
Published 2025-01-01“…These methods lack the ability to effectively model the nuanced dynamics of joint interactions and temporal progression, leading to limited generalization in recognizing complex actions.MethodsTo address these challenges, we propose PoseGCN, a Graph Convolutional Network (GCN)-based model that integrates spatial, temporal, and contextual features through a novel framework. …”
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13354
Up to half of companies would be behind on their climate targets under stricter scope 2 accounting rules
Published 2025-01-01“…In this paper we explore how such restrictions would quantitatively affect the scope 2 emissions and target progress reported by companies. We consider three accounting restrictions: geographical proximity, facility age, and power purchase agreement. …”
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13355
Differential Gene Expression Analysis in a Lumbar Spinal Stenosis Rat Model via RNA Sequencing: Identification of Key Molecular Pathways and Therapeutic Insights
Published 2025-01-01“…Conclusions: Our findings provide novel insights into the molecular mechanisms underlying LSS and offer potential avenues for the development of targeted therapies aimed at mitigating disease progression and improving patient outcomes.…”
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13356
How do serum cytokine levels change in myocarditis and inflammatory dilated cardiomyopathy relative to healthy individuals? A protocol for a systematic review and meta-analysis
Published 2025-02-01“…Irrespective of the factors responsible for this disease, cytokines play an important role in regulating the immunological response involved in its development and progression. Accordingly, this protocol aims to conduct a systematic review and meta-analysis summarising previous research on serum and plasma levels of cytokines in patients with myocarditis and inflammatory dilated cardiomyopathy.Methods and analysis Four scientific databases: PubMed, Embase, Scopus and Web of Science, will be searched. …”
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13357
The impact of uric acid on musculoskeletal diseases: clinical associations and underlying mechanisms
Published 2025-02-01“…HUA and gout may be risk factors for OA progression, although some reports suggest otherwise. …”
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13358
Oxidized DJ-1 Levels in Urine Samples as a Putative Biomarker for Parkinson’s Disease
Published 2018-01-01“…In addition, oxidative stress, such as 4-hydroxynonenal (HNE), oxidized protein, and dopamine quinone, are related to PD progression. DJ-1 is a PD-causative gene, and it plays a pivotal role as a sensor and eliminator of oxidative stress. …”
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13359
Extreme Event Statistics in Dst, SYM‐H, and SMR Geomagnetic Indices
Published 2023-03-01“…One minute resolution SYM‐H and SMR return levels progressively exceed that of Dst; their 5, 10, 50, and 100 year return levels exceed that of Dst by about 10%, 12%, 20% and 25% respectively. …”
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13360
Genetic advancements in breast cancer treatment: a review
Published 2025-02-01“…Personalized medicine, guided by genomic profiling, further enhances treatment precision by identifying patient-specific mutations, such as BRCA1 and BRCA2, allowing for more tailored and effective interventions. As research progresses, the constructive interaction between gene therapy, immunotherapy, and traditional approaches is paving the way for groundbreaking advancements in BC care. …”
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