The role of cyclooxygenase-2 (COX-2) and inflammatory markers in the progress of Alport syndrome in Egyptian children by Moushira Zaki, Hisham A. Orban, Mohamed A. Shahba, Rehab S. I. Moustafa, Ahmed Adel, Fatina I. Fadel, Abeer Selim, Hala T. El-Bassyouni, Eman R. Youness

“…This may highlight and speculate an innovative strategy for targeting the creation of safe and efficient anti-inflammatory treatments to inhibit disease progression in Alport syndrome.…”
Get full text

Can ChatGPT4-vision identify radiologic progression of multiple sclerosis on brain MRI? by Brendan S. Kelly, Sophie Duignan, Prateek Mathur, Henry Dillon, Edward H. Lee, Kristen W. Yeom, Pearse A. Keane, Aonghus Lawlor, Ronan P. Killeen

Subjects: Get full text

Time–Course Analysis of the Onset and Progression of Cuticle Cracking in Fruits of Cherry Tomato Cultivar ‘Nene’ by Ryosuke Hosoi, Kazuo Ikeda, Takashi Nishizawa, Tomoyuki Nabeshima

“…In this study, we collected basic information about the onset and progression of cuticular cracks in cherry tomatoes by observing the time–course of cuticular cracks incidence and severity during three cultivation periods. …”
Get full text

Research Progress on Bacteriocins Produced by Lactic Acid Bacteria and Their Inhibitory Effect on the Biofilm of Staphylococcus aureus by Xiaoge XUE, Yuanyuan LIU, Lina ZHANG, Rui FAN, Yu XIN, Jiage MA, Wei YU, Libo LIU

Get full text

Delay in seeking medication for oral cancer and its influencing factors – a review of research progress by Yuanyuan YANG, Jiegang HUANG, Huaming MAI, Qingsi OUYANG

“…Studies have shown that delays of more than three months between the onset of symptoms and seeking medical attention significantly increase the risk of oral cancer progression to advanced stages. This paper provides a comprehensive review of the current literature on delayed medical consultation in oral cancer patients, both nationally and internationally. …”
Get full text

Multidimensional evaluation of nutritional security policies in the Republic of Moldova: gaps, progress, and alignment with international standards by Rodica Siminiuc, Dinu Țurcanu, Sergiu Siminiuc

“…Educational and strategic policies show moderate progress, yet labeling, monitoring, and fiscal policies are underdeveloped, limiting their impact on public health.DiscussionThe results emphasize the need for a more coordinated, multi-sectoral approach, incorporating targeted fiscal incentives, systematic monitoring frameworks, and comprehensive educational reforms.…”
Get full text

Research Progress on Alleviatory Effects of 6-Gingerol and 6-Shogaol on Intestine Tight Junction Damage by LI Yu, OUYANG Fangxin, ZHANG He, WANG Wenyu, DONG Jingxiao, LI Dapeng, LI Feng

Get full text

Multi-Omics on Traditional Medicinal Plant of the Genus <i>Aconitum</i>: Current Progress and Prospect by Ting Wang, Cai Rangji, Wenbin Liu, Jing Ma, Ruichen Zhou, Liang Leng, Yi Zhang

Get full text

Microarray Analysis of Suppression Subtracted Hybridisation Libraries Identifies Genes Associated with Breast Cancer Progression by Dong Liu Barraclough, Susan Sewart, Philip S. Rudland, Balvinder S. Shoker, D. Ross Sibson, Roger Barraclough, Michael P. A. Davies

Get full text

Efficacy and Acceptability of Orthokeratology for Slowing Myopic Progression in Children: A Systematic Review and Meta-Analysis by Daizong Wen, Jinhai Huang, Hao Chen, Fangjun Bao, Giacomo Savini, Antonio Calossi, Haisi Chen, Xuexi Li, Qinmei Wang

“…To evaluate the efficacy and acceptability of orthokeratology for slowing myopic progression in children with a well conducted evidence-based analysis. …”
Get full text

Surface Plasmon Resonance-Based Biodetection Systems: Principles, Progress and Applications—A Comprehensive Review by Muhammad A. Butt

“…By providing a comprehensive overview of technological progress and emerging trends, this review underscores the transformative potential of SPR-based biodetection systems in addressing critical scientific and societal challenges. …”
Get full text

Research Progress on Genome-Scale Metabolic Models of Lactic Acid Bacteria and Their Application in the Food System by LIU Zihao, NI Haojie, LI Wenlu, WANG Fengzhong, WANG Yanbo, ZENG Hong

Get full text

Tuftelin 1 Facilitates Hepatocellular Carcinoma Progression through Regulation of Lipogenesis and Focal Adhesion Maturation by Lei Zhu, Kai X. Zhou, Ming Z. Ma, Lin L. Yao, Yan L. Zhang, Hui Li, Chang Du, Xiao M. Yang

“…Emerging evidences demonstrated critical roles of lipid de novo synthesis in HCC progression, yet its regulatory mechanisms are not fully understood. …”
Get full text

Expression of Concern: Snord 3A: A Molecular Marker and Modulator of Prion Disease Progression. by PLOS ONE Editors

Get full text

Mesenchymal Stem Cell-Derived Extracellular Vesicles: Roles in Tumor Growth, Progression, and Drug Resistance by Xiaoyan Zhang, Huaijun Tu, Yazhi Yang, Lijun Fang, Qiong Wu, Jian Li

“…Emerging evidences indicate that MSCs can also migrate to the tumor surrounding stroma and exert complex effects on tumor growth and progression. However, the effect of MSCs on tumor growth is still a matter of debate. …”
Get full text

Senescence-related circRNA circHIF-1α is associated with pancreatic cancer progression by Hao Hua, Yazu Deng, Dijie Zheng, Changhao Wu, Liwen Chen, Binbin Shi, Zhiwei He, Chao Yu

“…Abstract Recently, there has been growing interest in the role of circular RNAs (circRNAs) in the progression of human cancers. Cellular senescence, a known anti-tumour mechanism, has been observed in several types of cancer. …”
Get full text

COVID-19 vaccination and cerebral small vessel disease progression—A prospective cohort study by Yiu Ming Bonaventure Ip, Sangqi Pang, Alan Yao, Lucas Lau, Anki Miu, Katarina Chiu, Ho Ko, Andrew Kwok, Helen Y Chan, Sharon Lee, Howard Chan, Trista Hung, Bonnie Lam, Vincent Hui, Haipeng Li, Lin Shi, Jill Abrigo, Xinyi Leng, Yannie Soo, Sze Ho Ma, Vincent CT Mok, Hugh S Markus, Chris Mok, David SC Hui, Thomas W Leung

“…The primary outcome was progression of a composite of six standard cSVD biomarkers. …”
Get full text

The Uncoupling of Disease Activity from Joint Structural Progression in Patients with Rheumatoid Arthritis Treated with Filgotinib by Yoshiya Tanaka, Tatsuya Atsumi, Daniel Aletaha, Hendrik Schulze-Koops, Haruhiko Fukada, Chris Watson, Tsutomu Takeuchi

Subjects: Get full text

Research progress in the regulation of endothelial cells and smooth muscle cells using a micro–nanostructure by Songhao Liu, Juan Yan, Mengyu Gao, Hongxia Yang

Get full text

Reduction of elevated Gli3 does not alter the progression of autosomal recessive polycystic kidney disease by Lauren G. Russell, Maria Kolatsi‐Joannou, Laura Wilson, Jennifer C. Chandler, Nuria Perretta Tejedor, Georgie Stagg, Karen L. Price, Christopher J. Rowan, Tessa Crompton, Norman D. Rosenblum, Paul J. D. Winyard, David A. Long

“…We hypothesized that Hh pathway activity would be elevated during ARPKD pathogenesis, and its modulation may slow disease progression. We utilized Cpk mice which phenocopy ARPKD and generated a PKHD1‐mutant spheroid model in human collecting ducts. …”
Get full text