Case report: Low-dose radiation reverses pembrolizumab resistance in melanoma by Ka Hey Agnes Fong, Isaac Ho, Tsz Him So

“…However, upon disease progression on first- and second-line immunotherapy, further systemic treatment options are limited especially for cases without actionable molecular alterations. …”
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Assessing the impact of personal income tax reforms on the income inequality dynamics in Russia in the 21st century by M. L. Dorofeev

“…The purpose of this study is to analyse and assess the impact of reforms in the system of taxation of personal income on the dynamics of income inequality of Russian households. Dismantling the progressive personal income tax rate did not lead to a significant increase in income inequality in Russia, but the problem of excessive property inequality persisted until the beginning of 2022. …”
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Rare Case of Spinal Neurosarcoidosis with Concomitant Epidural Lipomatosis by Nesreen Jaafar, Maria Khoueiry, Samia J. Khoury, Achraf Makki

“…We describe a case of progressive myelitis in the presence of concomitant spinal neurosarcoidosis and epidural lipomatosis which was a challenging diagnosis with complete response to treatment after addressing both diseases. …”
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Guillain–Barré syndrome following Covishield vaccination in Telangana by Veeramalla N. Madhava Rao, Shivani Veeramalla, Yogesh Tekuru, Ramesh Kandimalla

“…Her initial presentation included symmetrical weakness in the lower limbs, which subsequently progressed to involve the upper limbs, facial muscles and oropharyngeal area. …”
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Historical overview of the dementia syndrome's emergence and evolution by Eslaidi Mendoza Clavel, Juana Adela Fong Estrada, Ariadna Céspedes Moncada

“…<p>Dementia is a syndrome usually of a chronic and progressive nature, in which there is an alteration of multiple higher cortical functions. …”
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Lesser Than Equal? by Saumya Uma

“… In India, Hindu family law is often touted as a progressive and gender-just law that ought to be emulated and extended to minority religious communities through a common civil code. …”
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Machine learning and AI for advancing Parkinson's disease diagnosis: exploring promising applications by Shohreh Abdollahi, Ramin Safa

“…Parkinson's disease is a progressive neurodegenerative disorder affecting millions worldwide. …”
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Cardiac Transplantation following Cobalt Cardiomyopathy from Bilateral Metal-on-Metal Hip Replacements by Peter Szedlak, Amrik Virdi, Paul Cacciottolo, Stephen Shepherd, Stephen Pettit, Florian Falter

“…A fifty-two-year-old man underwent heart transplantation at our centre after four years of developing progressive heart failure symptoms due to cobalt toxicity-related cardiomyopathy. …”
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Directly Converted Human Fibroblasts Mature to Neurons and Show Long-Term Survival in Adult Rodent Hippocampus by Natalia Avaliani, Ulrich Pfisterer, Andreas Heuer, Malin Parmar, Merab Kokaia, My Andersson

“…We transplanted human fibroblast-derived iNs into the adult rat hippocampus and observed a progressive morphological differentiation, with more developed dendritic arborisation at six months as compared to one month. …”
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Remarkable Presentation: Anaplastic Thyroid Carcinoma Arising from Chronic Hyperthyroidism by Habib G. Zalzal, Jeffson Chung, Jessica A. Perini

“…Chronic hyperthyroidism and toxic nodules are rarely associated with thyroid malignancy, with only one previous report documenting association with anaplastic thyroid carcinoma. Conclusion. Progressive thyroid enlargement and acute worsening of previously controlled hyperthyroidism should promote concern for disease regardless of baseline thyroid function.…”
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Mitochondrial Dysfunction in Parkinson's Disease by P. C. Keane, M. Kurzawa, P. G. Blain, C. M. Morris

“…Parkinson's disease (PD) is a progressive, neurodegenerative condition that has increasingly been linked with mitochondrial dysfunction and inhibition of the electron transport chain. …”
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Case Report of Rare Parathyroid Tumor with Atypical Presentation and Early Diagnosis by Érika Mayumi Ikeda Cavamura, Fabiane Karen Miyake, Jéssica Yachio Wiezel, Laura Schwartz Maranho, Luis Felipe Inglês Takada, Renata Cassitas Mendonça, Tamila Sohn Fagundes

“…The case report is a 49-year-old male patient who came to the emergency room of Mackenzie Evangelical University Hospital complaining of progressive “muscle weakness” and “joint” that started about 2 months ago. …”
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RISK ANALYSIS OF PESTE DES PETITS RUMINANTS INTRODUCTION INTO THE TERRITORY OF THE RUSSIAN FEDERATION by S. V. Scherbinin, A. K. Karaulov, V. M. Zakharov

“…Due to significant social and economic losses, negative effect on food safety of many countries of the world, peste des petits ruminants has been included in the List of priority diseases of the FAO/OIE Global Framework for the Progressive Control of Transboundary Animal Diseases (GF-TADs) A Five-Year Action Plan. …”
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Deep Brain Stimulation for Pantothenate Kinase-Associated Neurodegeneration by Pedro J. Garcia-Ruiz, Joaquin Ayerbe, Lydia Vela Desojo, Cici E. Feliz, Javier del Val Fernandez

“…Pantothenate kinase-associated neurodegeneration (PKAN) is usually associated with dystonia, which is typically severe and progressive over time. Pallidal stimulation (GPi DBS) has been carried out in selected cases of PKAN with drug-resistant dystonia with variable results. …”
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A mild case of Cockayne syndrome with a novel start-loss variant of ERCC8 by Taro Matsuoka, Takeshi Yoshida, Kengo Kora, Naoko Yano, Yoshihiro Taura, Takashi Nakamura, Takenori Tozawa, Jun Mori, Tomohiro Chiyonobu

“…Abstract Cockayne syndrome (CS) is a progressive multisystem disorder characterized by growth failure, microcephaly, developmental delay, and photosensitivity. …”
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Dysmorphic Short Stature: Radiological Diagnosis of Trichorhinophalangeal Syndrome by Corina Ramona Nicolescu, Laura Kasongo, Léon Rausin

“…A 14-year-old boy presented with short stature and distinctive facial features, and following the first clinical and biological evaluation, no precise diagnosis was reached. Progressive bilateral development of noninflammatory and painless deformity of his second finger required a radiological exam that highlighted the key elements (cone-shaped epiphyses) for final diagnosis. …”
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Marburg variant of multiple sclerosis: A young women case report by Mohammed Alaa Jameel, Wameth Alaa Jamel, Alaa Jameel Hasan, Riyam Amer Hammood Alkhuzaie

“…We report the case of a 15-years-old female presenting with progressive weakness over the limbs, hyperreflexia and loss of sensation by physical examination, lab tests and radiological investigations (MRI). …”
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Genesis of State Social Policy of Ukraine: Administrative and Legal Aspect by L. S. Katsalap

“…The author of the article studies and systematizes the set of available scientific achievements on the origin, formation and development of state social policy of Ukraine, considering the fact that one of the priorities of Ukrainian society in the need for progressive improvement of all mechanisms of public administration is the formation of effective social policy. …”
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Spontaneous bilateral chronic subdural haematoma in an 8-month-old male with osteogenesis imperfecta: A case report by Ekpene UU, Uduehe EE, Isobara I, Ndafia N

“…We present an 8-month-old male child with a 5-month history of progressive abnormal increase in the size of the head and a history of multiple long bone fractures not preceded by trauma and blue sclerae. …”
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Iron depletion in “metabolic fatty liver syndromes”: a strong biological rationale with disappointing liver outcomes by Amedeo Lonardo

“…Nonalcoholic fatty liver disease (NAFLD), its more rapidly progressive steatohepatitic variant [nonalcoholic steatohepatitis, (NASH)], and the recently defined metabolic dysfunction-associated fatty liver disease (MAFLD) may be collectively alluded to as “metabolic fatty liver syndromes” (MFLS). …”
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