Glucocorticoid-Induced Tumour Necrosis Factor Receptor-Related Protein: A Key Marker of Functional Regulatory T Cells by Simona Ronchetti, Erika Ricci, Maria Grazia Petrillo, Luigi Cari, Graziella Migliorati, Giuseppe Nocentini, Carlo Riccardi

“…In this review, we present data from mouse and human studies suggesting that GITR is a crucial player in the differentiation of thymic Tregs (tTregs), and expansion of both tTregs and peripheral Tregs (pTregs). The role of GITR in Treg expansion is confirmed by the association of GITR expression with markers of memory T cells. …”
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Towards the Application of Atorvastatin to Intensify Proapoptotic Potential of Conventional Antileukemic Agents In Vitro by Jolanta D. Żołnierczyk, Arleta Kaźmierczuk, Paweł Hikisz, Barbara Cebula-Obrzut, Ewa Wawrzyniak, Jerzy Z. Błoński, Małgorzata Misiewicz, Paweł Robak, Piotr Smolewski, Zofia M. Kiliańska

“…This study has revealed that in vitro atorvastatin increases the proapoptotic potential of cladribine and mafosfamide in CLL cells isolated from peripheral blood of patients. Moreover, a preincubation with the above statin sensitizes leukemic cells to CM-induced apoptosis even at small concentrations of the drug. …”
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Functional Change in the Caudal Pontine Reticular Nucleus Induced by Age-Related Hearing Loss by Ning Zhao, Ana’am Alkharabsheh, Fei Xu, Wei Sun

“…Although neural plasticity changes in the central auditory system after the peripheral lesions were suggested to underlie this phenomenon, the neurological cause of exaggerated ASR is still not clear. …”
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Case Report: Potential benefits of a single functional neurology intervention in athletic rehabilitation and recovery: a case study by Jorge Rey-Mota, Guillermo Escribano-Colmena, Eduardo Navarro Jiménez, Carmen Cecilia Laborde-Cárdenas, Rodrigo Yáñez-Sepúlveda, Vicente Javier Clemente-Suárez, Vicente Javier Clemente-Suárez

“…Then, we found how a single functional neurology intervention produced an improve in sports performance, pain and fatigue perceptions, and peripheral vascular response in an inter-national female weightlifting athlete with an initial incapacity to tolerate weight. …”
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B Cell Responses to CpG Correlate with CXCL16 Expression Levels in Common Variable Immunodeficiency by Vassilios Lougaris, Manuela Baronio, Massimiliano Vitali, Giacomo Tampella, Annarosa Soresina, Raffaele Badolato, Alessandro Plebani

“…We report that CXCL16 is normally expressed on B cells throughout peripheral maturation. Decreased B cell expression of CXCL16 was observed in a subgroup of CVID patients that correlated with defective in vitro responses to CpG (such as upregulation of CD69, CD86, AICDA, IL-6, and TLR9). …”
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Diagnosis of spondyloarthritis: Application of criteria in clinical practice by Sham Santhanam, Vinod Ravindran

“…The Assessment of SpA International Society (ASAS) group classifies SpA into axial SpA (axSpA) and peripheral SpA. axSpA was further divided into radiographic SpA and nonradiographic SpA. …”
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Arterial Hemodynamics in Prehypertensives by Chih-Tai Ting, Jaw-Wen Chen, Mau-Song Chang, Frank Chi-Pong Yin

“…Compared to age-matched normotensive adults, those with essential hypertension have been shown to have distinct arterial hemodynamic abnormalities consisting of increased peripheral resistance, pulse wave velocity, and wave reflection magnitude as well as decreased wave reflection time and aortic compliance. …”
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Neuroinflammation and Oxidative Stress in Diabetic Neuropathy: Futuristic Strategies Based on These Targets by Reddemma Sandireddy, Veera Ganesh Yerra, Aparna Areti, Prashanth Komirishetty, Ashutosh Kumar

“…In Diabetes, the chronic hyperglycemia and associated complications affecting peripheral nerves are one of the most commonly occurring microvascular complications with an overall prevalence of 50–60%. …”
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Ischemic Gangrene of the Glans following Penile Prosthesis Implantation by Borja García Gómez, Javier Romero Otero, Laura Díez Sicilia, Estibaliz Jiménez Alcaide, Eduardo García-Cruz, Alfredo Rodríguez Antolín

“…Ischemic gangrene following penile prosthesis implantation takes place in patients with poor peripheral vascularisation. Diabetes mellitus has been the common denominator to all of the reported cases.…”
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Effects of High Altitude on Sleep and Respiratory System and Theirs Adaptations by Turhan San, Senol Polat, Cemal Cingi, Gorkem Eskiizmir, Fatih Oghan, Burak Cakir

“…The most important step of acclimatization is the hyperventilation which is achieved by hypoxic ventilatory response of the peripheral chemoreceptors. Hyperventilation results in increase in arterial carbondioxide concentration. …”
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Ozone therapy and kinesiology effectiveness in the COVID-19 aftermath. Yaguaramas, 2022 by Maydelin Pérez Reina, Maria Caridad Pérez Reina, Jorge Enrique Rodríguez León, Elizabeth Núñez Pérez, Isidro Lamote Matos, Idalmis Valero Valero

“…</strong><br /><strong>Results:</strong> the female sex predominated (77.3%), ages between 50-54 years (27.3%); and peripheral polyneuropathy (81.8%) was the most frequent sequelae. 88.6% of patients considered a significant health impairment before treatment; After this, 68.2% did not consider any health impact. …”
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Free Triiodothyronine and Cholesterol Levels in Euthyroid Elderly T2DM Patients by F. Strollo, I. Carucci, M. Morè, G. Marico, G. Strollo, M. A. Masini, S. Gentile

“…Recent literature reports upon complex hypothalamic and peripheral interactions between T2DM and thyroid, and suggests T3 to enhance cholesterol synthesis and to have a role in insulin resistance states. …”
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Association of XRCC3, XRCC4, BAX, and BCL-2 Polymorphisms with the Risk of Breast Cancer by Emre Ozoran, Fadime Didem Can Trabulus, Duygu Erhan, Bahadir Batar, Mehmet Guven

“…Genetic analysis was performed using peripheral blood samples. Gene polymorphisms were detected by using polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) technique. 175 patients and 158 healthy controls were enrolled in the study. …”
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Specific Influences of Early Acoustic Environments on Cochlear Hair Cells in Postnatal Mice by Aoshuang Chang, Peng Chen, Shasha Guo, Nana Xu, Wenlu Pan, Hongzheng Zhang, Cuixian Li, Jie Tang

“…However, the effects of the acoustic environment on the functional development of the peripheral auditory system, especially the cochlear sensory hair cells, are still unclear. …”
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Fatal Multiorgan Failure Associated with Disseminated Herpes Simplex Virus-1 Infection: A Case Report by Michael Glas, Sigrun Smola, Thorsten Pfuhl, Juliane Pokorny, Rainer M. Bohle, Arno Bücker, Jörn Kamradt, Thomas Volk

“…Also complications to the peripheral and central nervous system, pneumonia or hepatitis are well known. …”
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Altered Immune Regulation in Type 1 Diabetes by András Zóka, Györgyi Műzes, Anikó Somogyi, Tímea Varga, Barbara Szémán, Zahra Al-Aissa, Orsolya Hadarits, Gábor Firneisz

“…Genomewide association studies have helped to understand the congenital susceptibility, and hand-in-hand with the immunological research novel paths of immune dysregulation were described in central tolerance, apoptotic pathways, or peripheral tolerance mediated by regulatory T-cells. …”
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The Evaluation of Plasma and Leukocytic IL-37 Expression in Early Inflammation in Patients with Acute ST-Segment Elevation Myocardial Infarction after PCI by Xin Wang, Xiangna Cai, Lan Chen, Duanmin Xu, Jilin Li

“…Methods. We collected peripheral venous blood from consented patients at 12 h, 24 h, and 48 h after PCI and healthy volunteers. …”
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Direct Spinal Ventral Root Repair following Avulsion: Effectiveness of a New Heterologous Fibrin Sealant on Motoneuron Survival and Regeneration by Mateus Vidigal de Castro, Roberta Barbizan, Rui Seabra Ferreira, Benedito Barraviera, Alexandre Leite Rodrigues de Oliveira

“…Axonal injuries at the interface between central and peripheral nervous system, such as ventral root avulsion (VRA), induce important degenerative processes, mostly resulting in neuronal and motor function loss. …”
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Moderate hypothermic circulatory arrest with antegrade cerebral perfusion for the open repair of juxtarenal abdominal aortic aneurysm repair with shaggy aorta by Yamini Vyas, MD, Jane M. Chung, MD, Yakov L. Elgudin, MD, PhD, Jae S. Cho, MD

“…Shaggy aorta is severe luminal surface degeneration of the aorta leading to an increased risk of plaque destabilization and embolization to the peripheral or visceral vessel beds. It represents a challenging clinical entity for both endovascular and open repair owing to potential atheroembolization, increased early morbidity and mortality, and poor long-term survival. …”
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Asymmetrical labium majus enlargement (CALME) in childhood: A series of clinical cases by Zalina K. Batyrova, Zaira Kh. Kymykova, Elena V. Uvarova, Alina S. Badlaeva, Aleksandra V. Asaturova, Polina V. Kulabukhova, Fatima Sh. Mamedova, Vladimir D. Chuprynin, Irina A. Yagovkina

“…Childhood asymmetry labium majus enlargement (CALME) is a rare, benign disease of pre-pubertal age characterized by non-neoplastic unilateral proliferation of the soft tissues of the vulva without a peripheral capsule. The pathogenesis of CALME is not completely clear. …”
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