Adaptive Immunity in Ankylosing Spondylitis: Phenotype and Functional Alterations of T-Cells before and during Infliximab Therapy by Balázs Szalay, Gergő Mészáros, Áron Cseh, Lilla Ács, Magdolna Deák, László Kovács, Barna Vásárhelyi, Attila Balog

“…Flow cytometry was used to determine T-cell subsets in peripheral blood and their intracellular signaling during activation. …”
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Study of characteristics of vortex tube by V. I. Kuznetsov, V. V. Makarov, A. S. Gritsay

“…The calculations take into account the exchange of work and heat between the axial and peripheral gas layers. The exchange of work is carried out due to the transfer of kinematic energy from the axis to the periphery by viscosity forces when tangential stresses occur. …”
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Exploring the nexus of migration dynamics and urban expansion: key drivers of horizontal spatial growth in Woldia Township, Ethiopia by Mulu Fasigo Fente, Birhanu Girma Abebe, Mintesnot Gebeyehu Woldeamanuel

“…This study aims to explore the key drivers behind the horizontal growth of Woldia, particularly in its peripheral areas. Data were collected through a structured questionnaire administered to a randomly selected sample of 395 respondents, complemented by key informant interviews and secondary data sources. …”
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Evaluation of CD4+ T Lymphocyte Counts to Predict Survival of ICU Patients with Sepsis Using Sepsis-3 Criteria: A Prospective Cohort Study by Guoge Huang, Xusheng Li, Chunmei Zhang, Haizhong Li, Mengling Jian, Chunyang Huang, Yingqin Zhang, Luhua Xian, Hongke Zeng, Yuanyuan Xia, Wenqiang Jiang

“…We conducted a prospective, observational cohort study in a general ICU and enrolled patients with sepsis using the Sepsis-3 criteria. Peripheral blood samples were collected within 24 hours of enrollment or measurement of blood cell analysis and biomarkers of CD4+ T lymphocytes and CD8+ T lymphocytes. …”
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Cernunnos/XLF Deficiency: A Syndromic Primary Immunodeficiency by Funda Erol Çipe, Cigdem Aydogmus, Arzu Babayigit Hocaoglu, Merve Kilic, Gul Demet Kaya, Elif Yilmaz Gulec

“…Because of that she had low IgG and IgA levels, normal IgM level, and absence of B cells in peripheral blood; she was considered as primary immunodeficiency, Nijmegen breakage syndrome. …”
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Integrated Analysis of mRNA and lncRNA Expression Profiles Reveals Regulatory Networks Associated with Decompensated Cirrhosis by Li Zhang, Xiaoyu Fang, Suhua Wang, Shasha Ma, Jinyan Zhang, Xiang Dong, Jing Dai, Chuanmiao Liu, Yu Gao

“…RNA was isolated from peripheral blood mononuclear cells, and RNA-seq was used for transcriptome analysis. …”
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Analysis of the impact of space organization on the viability of the Karaj metropolitan core by behrouz hashemi, farzaneh sasanpor, ali movahed, Habiallah Fasihi

“…The results show that the Karaj metropolitan organization and spatial structure are interconnected and connected to some of the major routes, forming sub-nuclei away from the core and thus transferring the functional and service applications from the center to be the peripheral nucleus. This has affected the viability of the core. …”
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A Precocious Cerebellar Ataxia and Frequent Fever Episodes in a 16-Month-Old Infant Revealing Ataxia-Telangiectasia Syndrome by Luigi Nespoli, Annapia Verri, Silvia Tajè, Francesco Paolo Pellegrini, Maddalena Marinoni

“…Other investigations showed leukocytopenia with lymphopenia, reduced IgG2 and IgA levels, and low titers of specific postimmunization antibodies against tetanus toxoid and Haemophilus B polysaccharide. Peripheral lymphocytes subsets showed reduction of T cells with a marked predominance of T cells with a memory phenotype and a corresponding reduction of naïve T cells; NK cells were very increased (41%) with normal activity. …”
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CXCR6 Expression Is Important for Retention and Circulation of ILC Precursors by Sylvestre Chea, Cécilie Possot, Thibaut Perchet, Maxime Petit, Ana Cumano, Rachel Golub

“…We demonstrate that the ILC frequency is maintained due to a significant increase of ILC peripheral proliferation, as well as an increased proliferation of the in situ ILC precursors to compensate their retention in the bone marrow.…”
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A Turner Syndrome Patient Carrying a Mosaic Distal X Chromosome Marker by Roberto L. P. Mazzaschi, Juliet Taylor, Stephen P. Robertson, Donald R. Love, Alice M. George

“…This was later confirmed on peripheral blood cultures by conventional G-banding, fluorescence in situ hybridisation and microarray analysis. …”
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Pure Testicular Seminoma Relapsing Late with Somatic Type Malignancy by Klaus-Peter Dieckmann, Petra Anheuser, Ralf Gehrckens, Waldemar Wilczak, Guido Sauter, Doris Höflmayer

“…Histologically, the specimen consisted of neurofibroma with areas of malignant peripheral nerve sheath tumour and spots with mature bone formation. …”
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Comparison of Two New Mouse Models of Polygenic Type 2 Diabetes at the Jackson Laboratory, NONcNZO10Lt/J and TALLYHO/JngJ by Edward H. Leiter, Marjorie Strobel, Adam O'Neill, David Schultz, Andrew Schile, Peter C. Reifsnyder

“…Unlike the leptin receptor-deficient db/db models with central leptin resistance, the new models develop a progressive peripheral leptin resistance and are able to maintain reproductive function. …”
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Metagenomic next-generation sequencing assists in the diagnosis of visceral leishmaniasis in non-endemic areas of China by Rui Zhao, Guilun He, Lin Xiang, Melinda Ji, Rongheng He, Xudong Wei

“…In this study, we report two cases of leishmaniasis from Henan Province, China, in which Leishmania parasites were identified using mNGS technology, massively expediting diagnosis and treatment.ResultsOur report demonstrates that the mNGS method is applicable to peripheral blood samples (PB), which are far more readily available in clinical settings, in addition to bone marrow aspirate samples (BM), which are traditionally used for diagnosis of visceral leishmaniasis.ConclusionOur report validates the efficacy of mNGS technology as a rapid and accurate method of diagnosis for leishmaniasis.…”
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Temperature Field Variation Law of Low Exothermic Polymer Grouting Material in Repairing Void Damage of Frozen Soil Subgrade by Bei Zhang, Baolin Wang, Yanhui Zhong, Shuangjie Wang, Xiaolong Li, Shilun Wang

“…During the natural cooling process, the peripheral temperature of the ring isotherm first decreased and a negative temperature ring-shaped isotherm gradually formed. …”
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Neuroprotective Activity of (-)-Epigallocatechin Gallate against Lipopolysaccharide-Mediated Cytotoxicity by Jin-Biao Liu, Li Zhou, Yi-Zhong Wang, Xu Wang, Yu Zhou, Wen-Zhe Ho, Jie-Liang Li

“…In addition, EGCG significantly diminished LPS-induced inflammatory cytokines in the peripheral mononuclear blood cells (PBMCs). Supernatant from EGCG-pretreated and LPS-activated macrophage cultures was found to be less cytotoxic to neurons than that from non-EGCG-pretreated and LPS-activated macrophage cultures. …”
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Follicular Helper CD4+ T Cells in Human Neuroautoimmune Diseases and Their Animal Models by Xueli Fan, Chenhong Lin, Jinming Han, Xinmei Jiang, Jie Zhu, Tao Jin

“…It is difficult and impossible to get access to secondary lymphoid tissues in humans, so studies are usually performed with human peripheral blood samples as circulating counterparts of tissue TFH cells. …”
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Gait Impairment in a Rat Model of Focal Cerebral Ischemia by Saara Parkkinen, Francisco J. Ortega, Kristina Kuptsova, Joanna Huttunen, Ina Tarkka, Jukka Jolkkonen

“…The automated, quantitative CatWalk system, which was initially designed to measure gait in models of spinal cord injury, neuropathic pain, and peripheral nerve injury, is said to be a useful tool for the study of motor impairment in stroke animals. …”
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Divergent Crosstalk Between Microglia and T Cells in Brain Cancers: Implications for Novel Therapeutic Strategies by Min-Hee Yi, Jinkyung Lee, Subin Moon, EunA So, Geonhyeok Bang, Kyung-Sub Moon, Kyung-Hwa Lee

“…Within this complex ecosystem, microglia and macrophages play fundamental roles, forming intricate networks with peripheral immune cell populations, particularly T cells. …”
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Tissue‐resident memory T cells in diseases and therapeutic strategies by Daoyuan Xie, Guanting Lu, Gang Mai, Qiuyan Guo, Guofeng Xu

“…Unlike circulating memory T cells, TRM cells are located within peripheral tissues, and they play vital roles in antiviral, antibacterial, and antitumor immunity. …”
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Nucleotides Regulate Secretion of the Inflammatory Chemokine CCL2 from Human Macrophages and Monocytes by K. R. Higgins, W. Kovacevic, L. Stokes

“…UTP stimulation of human peripheral CD14+ monocytes showed low responses to LPS (4-hour stimulation) but a significant increase above background following 6 hours of treatment. …”
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