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1361
Brown fat thermogenesis and branched-chain amino acids in metabolic disease
Published 2024-02-01“…Recent advances in metabolomics, advanced imaging techniques, and genetic analyses over the past decade have enabled newfound insights into the mechanism of BCAA metabolic dysregulation across a variety of peripheral tissues and its impact on metabolic disease, suggesting a key role for brown adipose tissue (BAT) in determining BCAA metabolic homeostasis. …”
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1362
Post infectious fatigue and circadian rhythm disruption in long-COVID and other infections: a need for further research
Published 2025-02-01“…Epigenetic changes, including DNA methylation at clock-related loci, particularly in peripheral tissues, further contribute to systemic circadian dysregulation. …”
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1363
Genotoxicity Assessment of Multispecies Probiotics Using Reverse Mutation, Mammalian Chromosomal Aberration, and Rodent Micronucleus Tests
Published 2013-01-01“…Ames tests, in vitro mammalian chromosome aberration assay, and micronucleus tests in mouse peripheral blood are performed. For 5 strains of Salmonella Typhimurium, the Ames tests show no increased reverse mutation upon exposure to the test substance. …”
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1364
Operation and Economic Analysis for Ring Road: Baqubah City as Case Study
Published 2022-01-01“…In this research, Baqubah city is subjected to economic analyses in order to determine whether the establishment of a peripheral ring road to downgrade the traffic congestion in the city center would be economically feasible. …”
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1365
Evaluation of Heavy Silicon Oil in the Treatment of Retinal Detachment Mainly Iinvolving Lower Quadrants
Published 2024-05-01“…Statistically significantly more retinotomies were performed in the eyes with recurrent retinal detachment. Residual peripheral vitreous required removal during repair surgery in the eyes with recurrent retinal detachment. …”
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1366
Regularities of mechanical behavior of steel 40Cr during the postcritical deformation of specimens in condition of necking effect at tension
Published 2018-01-01“…It is shown that the material in the peripheral areas of the gauge length of the sample is in a strengthened state, which does not depend on the degree of previously achieved postcritical deformation, and the strength of the material in the neck-forming zone on the initial specimens is thereby increased…”
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1367
Ramsay Hunt Syndrome Associated with Central Nervous System Involvement in an Adult
Published 2016-01-01“…We describe a 55-year-old diabetic female who presented with gait ataxia, right peripheral facial palsy, and painful vesicular lesions involving her right ear. …”
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1368
Neuronal Differentiation of Adipose Derived Stem Cells: Progress So Far
Published 2014-01-01“…Unfortunately the nervous system has a limited capacity for self-repair and there are a plethora of disorders, diseases, and types of trauma that affect the central and peripheral nervous systems; however, current treatment modalities are unable to remedy them. …”
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1369
A Rare Case of Supinator Intramuscular Myxoma with Encasement of the Posterior Interosseous Nerve
Published 2019-01-01“…Magnetic resonance imaging showed a lobulated multiseptated lesion seen within left supinator muscle, which was hyperintense on T2-weighted images (T2WI) and hypointense on T1-weighted images (T1WI), with peripheral enhancement post contrast. The tissue diagnosis of myxoma was confirmed via an open biopsy. …”
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1370
Simultaneous Manifestation of Chronic Myelomonocytic Leukemia and Multiple Myeloma during Treatment by Prednisolone and Eltrombopag for Immune-Mediated Thrombocytopenic Purpura
Published 2016-01-01“…Four years later, there was a prominent increase of peripheral blood monocytes, which was accompanied by recurrence of thrombocytopenia. …”
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1371
Celiac trunk angiography with balloon occlusion of splenic artery for diagnosis and treatment of splenic steal syndrome
Published 2025-03-01“…Splenic steal syndrome (SSS) post liver transplant is a potential cause of graft dysfunction in the setting of peripheral hepatic arterial bed resistance and redirection of blood flow to a dominant splenic artery resulting in reduction of hepatic arterial inflow. …”
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1372
Treatment of Coexisting Chronic Neutrophilic Leukemia and Light Chain Multiple Myeloma with Hydroxyurea, Bortezomib, and Dexamethasone
Published 2014-01-01“…Complete blood count (CBC) revealed neutrophilia with band predominance and mild thrombocytopenia. Peripheral blood flow cytometry was unremarkable without any evidence of lymphoproliferative disorder or myeloblasts. …”
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1373
Bispecific antibody-mediated redirection of NKG2D-CAR natural killer cells facilitates dual targeting and enhances antitumor activity
Published 2021-10-01“…The ability of this molecule, termed NKAB-ErbB2, to redirect NKG2D-expressing effector cells to ErbB2-positive tumor cells of different origins was investigated using peripheral blood mononuclear cells, ex vivo expanded NK cells, and NK and T cells engineered with an NKG2D-based chimeric receptor.Results On its own, bispecific NKAB-ErbB2 increased lysis of ErbB2-positive breast carcinoma cells by peripheral blood-derived NK cells endogenously expressing NKG2D more effectively than an ErbB2-specific IgG1 mini-antibody able to induce antibody-dependent cell-mediated cytotoxicity via activation of CD16. …”
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1374
Muscarinic acetylcholine type 1 receptor antagonism activates TRPM3 to augment mitochondrial function and drive axonal repair in adult sensory neurons
Published 2025-02-01“…Objective: Antagonism of the muscarinic acetylcholine type 1 receptor (M1R) promotes sensory axon repair and is protective in peripheral neuropathy, however, the mechanism remains elusive. …”
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1375
Study on the Deformation Mechanism of the Bottom Plate along the Empty Lane of Deep Mining and the Control Technology of the Bottom Drum
Published 2022-01-01“…During mining, under the comprehensive action of the original peripheral stress field and the mining stress field, the cliffhanger is unstable under the comprehensive action of the original peripheral stress field and the mining stress field, and the extrusion and stretching effect of the unflapped part of the rock layer above the goaf section of the coal seam is set up along the air, resulting in violent deformation such as the bottom drum, and the rotational sinking of this part of the unflinted rock layer further aggravates the transfer of the overburden load to the surrounding rock of the lane, so that the surrounding rock along the empty lane is subjected to a large additional stress, and the mining stress field plays a leading role, and the mining stress “far field” is the compound stress field, of which the tensile stress is the leading destructive factor. …”
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1376
The efficacy of neoadjuvant immunotherapy and lymphocyte subset predictors in locally advanced esophageal squamous cell carcinoma: A retrospective study
Published 2024-09-01“…Evaluating the differentiation status and dynamic changes of peripheral blood immune cells may provide valuable predictive insights into treatment efficacy and prognosis.…”
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1377
L’ensemble monumental du Pâtis à Vieillevigne (Loire-Atlantique) : un nouvel exemple de complexe sur cour laténien en Gaule
Published 2024-12-01“…The western porch, supported by four posts, was the main entrance to the site, complemented by a gate on the eastern side.Perfectly centred within the enclosure, a building with a courtyard and peripheral galleries was uncovered. It is set in a 46 m square with a surface area of 2200 m2. …”
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1378
Effect of Early Mobilization on Respiratory and Limb Muscle Strength and Functionality of Nonintubated Patients in Critical Care: A Feasibility Trial
Published 2020-01-01“…To assess the potential effectiveness or efficacy of early mobilization on respiratory and peripheral muscle strengths and functionality in nonintubated patients. …”
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1379
Quantitative N-glycoproteomic analysis reveals glycosylation signatures of plasma immunoglobulin G in systemic sclerosis
Published 2025-02-01“…These changes in the levels of intact N-glycopeptides are associated with various aspects of SSc, including diffuse SSc (dSSc), interstitial lung disease (ILD), disease progression, cardiovascular involvement and C-reactive protein in the peripheral blood. In summary, this study offers a detailed overview of the intact N-glycopeptide profile in the peripheral blood of patients with SSc, providing valuable insights that could propel further research into SSc.…”
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1380
Characteristics and multi-omics analysis of spontaneous spondyloarthritis in non-human primates: Case report
Published 2025-01-01“…X-ray imaging results revealed that crab-eating monkeys (Macaca fascicularis) with spontaneous spondyloarthritis developed bone spurs in the spine and experienced bone destruction in peripheral joints. MRI imaging further confirmed inflammatory changes in the spine and facet joints of these monkeys, along with inflammation and bone destruction in peripheral joints. …”
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