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1181
Impact of Methotrexate and 7‐Hydroxymethotrexate Exposure on Renal Toxicity in Pediatric Non‐Hodgkin Lymphoma
Published 2025-01-01“…Results A three‐compartment chain model (central and peripheral compartments for MTX and central compartment 7‐OHMTX) with the first‐order elimination adequately characterized the in vivo process of MTX and 7‐OHMTX. …”
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1182
Immunoregulatory Effects of Subcutaneous Immunotherapy on Lymphocyte Subgroups and Cytokines in Children with Asthma
Published 2019-01-01“…Here, we investigated the effects of SCIT on cytokine production and peripheral blood levels of lymphocyte subtypes in children with mite-induced moderate and severe allergic asthma. …”
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1183
Large-scale screening of HIV-1 T-cell epitopes restricted by 12 prevalent HLA-A allotypes in Northeast Asia and universal detection of HIV-1-specific CD8+ T cells
Published 2025-02-01“…Peripheral blood mononuclear cells (PBMCs) were collected from 96 individuals with HIV-1 and cocultured ex vivo with each candidate peptide epitope, followed by the detection of activated CD8+ T cells. …”
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1184
Acute effects on hepatic biomarkers in the freshwater native fish Aequidens metae exposed to polycyclic aromatic hydrocarbons
Published 2023-10-01“…Water quality variables, total protein content, 7-ethoxyresorufin-O-deethylase activity, liver histopathological changes and genotoxic alterations in peripheral blood were measured during the assay.FINDING: In polycyclic aromatic hydrocarbons-exposed fish, analysis of liver tissue revealed parenchymal lesions and changes in the number and shape of hepatocyte nuclei. …”
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1185
Diagnosis and management of type 2 diabetes mellitus in patients with ischaemic heart disease and acute coronary syndromes - a review of evidence and recommendations
Published 2025-01-01“…It is characterised by persistently elevated blood glucose occurring as a result of peripheral insulin resistance and reduced insulin production which may lead to multiple long-term health conditions such as retinopathy, neuropathy, and nephropathy. …”
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1186
MicroRNA Expression in Cutaneous Lupus: A New Window to Understand Its Pathogenesis
Published 2019-01-01“…HD. miR-150, miR-1246, and miR-21 levels were downregulated in DLE vs. HD. Peripheral CD4+/CD25-/IL-4+ cells and CD4+/CD25hi/Foxp3+ were negatively associated with miR-23b, and CD4+/CD25-/IFN-γ+ with miR-1246 in SCLE, whereas CD123+/CD196+/IDO+ cells were positively associated with miR-150 in DLE. …”
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1187
Physical Examination & Health Assessment /
Published 2016Table of Contents: “…Evidence-based assessment -- Cultural competence -- The interview -- The complete health history -- Mental status assessment -- Substance use assessment -- Domestic and family violence assessments -- Assessment techniques and safety in the clinical setting -- General survey, measurement, vital signs -- Pain assessment: the fifth vital sign -- Nutritional assessment -- Skin, hair, and nails -- Head, face, and neck, including regional lymphatics -- Eyes -- Ears -- Nose, mouth, and throat -- Breasts and regional lymphatics -- Thorax and lungs -- Heart and neck vessels -- Peripheral vascular system and lymphatic system -- Abdomen -- Musculoskeletal system -- Neurologic system -- Male genitourinary system -- Anus, rectum, and prostate -- Female genitourinary system -- The complete health assessment: adult -- The complete physical assessment: infant, child, and adolescent -- Bedside assessment and electronic health recording -- The pregnant woman -- Functional assessment of the older adult.…”
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1188
Leptospirosis Presenting with Features of Thrombotic Microangiopathy
Published 2020-01-01“…A 48-year-old male presented to a peripheral hospital with a short history of diarrhoea, anaemia, hyperbilirubinemia, raised lactate dehydrogenase, thrombocytopenia, and severe acute kidney injury and was transferred to our tertiary care kidney centre. …”
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1189
Modulation of Tumor Tolerance in Primary Central Nervous System Malignancies
Published 2012-01-01“…Thus, it is an open question whether tumor tolerance in the brain is fundamentally different from that of peripheral sites of tumorigenesis or whether it simply stands as a particularly strong example of such tolerance.…”
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1190
Causes and factors of deindustrialization in old industrial regions
Published 2023-12-01“…Exclusive ways to restore industrial production in the CFD regions have been identified: innovation transfer based on the experience of techno-zones, special economic zones, territories of advanced development, and technoparks; integrated use of natural resources; modernization of high-tech industries; industrial agglomerations development in the peripheral territories of the federal subjects. The results of the study can be applied in the process of building strategic plans for revival of industrial production, first of all, when ensuring import substitution and strengthening the country’s defense capability. …”
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1191
Circulating Tumor Cells Measurements in Hepatocellular Carcinoma
Published 2012-01-01“…Our aim is to review and analyze the different new methods existing to detect, enumerate, and characterize the CTC in the peripheral circulation of patients with HCC.…”
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1192
Improving the Validity of Squeeze Film Air-Damping Model of MEMS Devices with Border Effect
Published 2014-01-01“…The published squeezed film air damping models are generally derived from the analytical solutions of Reynolds equation or its other modified forms under the supposition of trivial pressure boundary conditions on the peripheral borders. These treatments ignoring the border effect can not give faithful result for structure with smaller air venting gap or the double-gimbaled structure in which the inner frame and outer one affect the air venting. …”
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1193
Tau-Reactive Endogenous Antibodies: Origin, Functionality, and Implications for the Pathophysiology of Alzheimer’s Disease
Published 2019-01-01“…Herein, we review recent data showing the occurrence of tau-reactive antibodies in the brain and peripheral circulation and discuss their origin and significance in tau clearance. …”
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1194
Evidence for local inflammation in complex regional pain syndrome type 1
Published 2002-01-01“…Background: The pathophysiology of complex regional pain syndrome type 1 (CRPS 1) is still a matter of debate. Peripheral afferent, efferent and central mechanisms are supposed. …”
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1195
A conformação dos grupos de pesquisa em biotecnologia da cana de açúcar na região norte-fluminense: a perspectiva do "novo sistemismo"
Published 2005-01-01“…We confirm, thus, the tendency that the process of generation of technology in peripheral countries works due to a structural coupling between State, science and economy, whereas, in the main countries, this process is made independently of the main performance of the first one.…”
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1196
Chemoresistance, Cancer Stem Cells, and miRNA Influences: The Case for Neuroblastoma
Published 2015-01-01“…Neuroblastoma originates within the peripheral sympathetic ganglia, with 30% of the cases developing within the adrenal medulla, although it can also occur within other regions of the body such as nerve tissue in the spinal cord, neck, chest, abdomen, and pelvis. …”
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1197
Clinical and Pathogenetic Parallels of Nonalcoholic Fatty Liver Disease and Gallstone Disease
Published 2019-03-01“…These include central and peripheral insulin resistance, changes in the expression of transcription factors (liver X-receptor and farnesoid X-receptor) and the bile acid membrane receptors (TGR5). …”
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1198
Eosinophilic mastitis: A chameleon disease in rheumatologists' domain
Published 2019-01-01“…Because presentation can be similar and confusing enough, we took a cue from the history of asthma, urticaria, and peripheral eosinophilia to clinch the diagnosis of eosinophilic mastitis, which was further confirmed on biopsy. …”
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1199
A Case Report of Eosinophilic Esophagitis Accompanying Hypereosinophilic Syndrome
Published 2012-01-01“…Hypereosinophilic syndrome is a blood disorder characterized by the overproduction of eosinophils in the bone marrow with persistent peripheral eosinophilia, associated with organ damage by the release of eosinophilic mediators. …”
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1200
Transportation, Social Inequality and Spatial Capital: Comparative Analysis between Buenos Aires and Santiago de Chile
Published 2016-09-01“…The study cases compare four neighborhoods from Buenos Aires and Santiago de Chile, two peripherals and two pericentrals. The results show, considering the role of new infrastructure, a strong difference between residents from the peripheral cases and little difference in the pericentral cases, identifying, however, processes of a dispute over the ownership and use of urban space and the neighborhood, in all the cases.…”
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