Transcriptional Profiling at High Temporal Resolution Reveals Robust Immune/Inflammatory Responses during Rat Sciatic Nerve Recovery by Lingyan Xing, Qiong Cheng, Guangbin Zha, Sheng Yi

“…After peripheral nerve injury, immune/inflammatory responses are triggered, which are critical for nerve regeneration. …”
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Deranged aortic intima-media thickness, plasma triglycerides and granulopoiesis in Sl/Sld mice by Kottarappat N. Dileepan, Thomas P. Johnston, Yuai Li, Ossama Tawfik, Daniel J. Stechschulte

“…STUDIES were carried out to evaluate the impact of a high-fat dietary regimen on aortic wall thickness, peripheral blood leukocyte profile, and plasma cholesterol and triglyceride levels in the mast cell-deficient Sl/Sld mouse. …”
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Latanoprost Induced Iris Pigment Epithelial and Ciliary Body Cyst Formation in Hypermetropic Eyes by Abhijit Anand Mohite, Rangarajan V. Prabhu, Thomas Ressiniotis

“…We report the first documented case of bilateral IPE and CB cysts in a hypermetropic patient with prior laser peripheral iridotomies (LPIs) as a rare, delayed side effect of topical Latanoprost treatment. …”
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Th22 Cells/IL-22 Serves as a Protumor Regulator to Drive Poor Prognosis through the JAK-STAT3/MAPK/AKT Signaling Pathway in Non-Small-Cell Lung Cancer by Yinan Yao, Guangdie Yang, Guohua Lu, Jiani Ye, Luyun Cui, Zhu Zeng, Junjun Chen, Jianying Zhou

“…It was initially found that Th22 cells were enriched in the peripheral blood of NSCLC patients. The level of Th22 cells in peripheral blood mononuclear cells (PBMCs) was positively correlated with the TNM stage, lymph node metastasis, and clinical tumor biomarkers. …”
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Descemet Stripping Endothelial Keratoplasty in a Patient with Keratoglobus and Chronic Hydrops Secondary to a Spontaneous Descemet Membrane Tear by Anton M. Kolomeyer, David S. Chu

“…Vision was 20/60 with pinhole. 360-degree peripheral corneal ectasia with mild neovascularization and hydrops was present. …”
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A Rare Case of Eosinophilic Granulomatosis with Polyangiitis Associated with Cryoglobulinemia Presenting with a Bullous Skin Eruption of the Lower Limbs by D. D. K. Abeyaratne, C. Liyanapathirana, C. L. Fonseka, P. W. M. C. S. B. Wijekoon

“…Blood investigations revealed a marked peripheral eosinophilia with positive P-ANCA. Skin biopsy was suggestive of leukocytoclastic vasculitis. …”
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A Unique Case of Autoimmune Retinopathy Associated with Anti-Alpha-Enolase Antibodies by Paul A. Kurz, Rachel E. Reem, Daryl E. Kurz, Richard G. Weleber

“…A 30-year-old male experienced recurrent, primarily peripheral visual field disturbances and minimal photopsia, with interval symptom resolution. …”
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Spindle Cell Melanoma Presenting as an Ulcer in a Black Diabetic by D. A. Gaskin, D. Brathwaite, N. Depeiza, P. S. Gaskin, J. Ward

“…There was a 1×1.5 cm ulcer with a necrotic base which bled easily on contact with no evidence of peripheral neuropathy nor arterial insufficiency. Microscopic examination of a biopsy of the lesion showed fascicles of spindle cells with plump nuclei and intracytoplasmic yellow-brown pigment. …”
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Effects of Microtubule Stabilization by Epothilone B Depend on the Type and Age of Neurons by Eun-Hae Jang, Aeri Sim, Sun-Kyoung Im, Eun-Mi Hur

“…Paradoxically, administration of MSAs, which have been widely prescribed to treat malignancies, is well known to cause debilitating peripheral neuropathy and axon degeneration. Despite the growing interest of applying MSAs to treat the injured or degenerating central nervous system (CNS), consequences of MSA exposure to neurons in the central and peripheral nervous system (PNS) have not been thoroughly investigated. …”
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Basal Cell Carcinoma: 10 Years of Experience by Emanuele Cigna, Mauro Tarallo, Michele Maruccia, Valentina Sorvillo, Alessia Pollastrini, Nicolò Scuderi

“…Although guidelines indicate 3 mm peripheral margin of excision in BCC <2 cm, in our experience, a margin of less than 5 mm results in a high risk of incomplete excisions.…”
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Vitreous Hemorrhage as Presenting Sign of Retinal Arteriovenous Malformation by Geraldine P. B. M. Accou, Fanny Nerinckx, Bart P. Leroy, Julie De Zaeytijd

“…To describe a patient with vitreous hemorrhage and peripheral retinal ischemia, eventually diagnosed with an underlying retinal arteriovenous malformation. …”
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Trigeminal Neuralgia, Glossopharyngeal Neuralgia, and Myofascial Pain Dysfunction Syndrome: An Update by Mohammad Khan, Shamima Easmin Nishi, Siti Nazihahasma Hassan, Md. Asiful Islam, Siew Hua Gan

“…These types of pain can be experienced after nerve injury or as a part of diseases that affect peripheral and central nerve function, or they can be psychological. …”
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Acute Myeloid Leukemia with Basophilic Differentiation Transformed from Myelodysplastic Syndrome by Yasuhiro Tanaka, Atsushi Tanaka, Akiko Hashimoto, Kumiko Hayashi, Isaku Shinzato

“…We should keep in mind that MDS could transform to AML with basophilic differentiation when peripheral basophilia in addition to myeloblasts develops in patients with MDS.…”
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Acute stimulation of PBMCs drives switch from dopamine-induced anti- to proinflammatory phenotype of monocytes only in women by Leonie Fleige, Silvia Capellino

“…However, a deeper understanding of these differences in peripheral immune cells remains limited. In this study, we investigated the effects of dopaminergic stimulation on activation and cytokine secretion of peripheral blood mononuclear cells from women and men using flow cytometry, ELISA, and multiplex assays. …”
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Strongyloides Hyperinfection in a Renal Transplant Patient: Always Be on the Lookout by Murtaza Mazhar, Ijlal Akbar Ali, Nelson Iván Agudelo Higuita

“…The patient was treated with a three-week course of ivermectin with complete resolution of signs, symptoms, peripheral eosinophilia, and the positive IgG serology. …”
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Autoimmune Hepatitis: Progress from Global Immunosuppression to Personalised Regulatory T Cell Therapy by Nwe Ni Than, Hannah C. Jeffery, Ye H. Oo

“…The precise aetiology of AIH is still unknown but current evidence suggests both genetic and environmental factors are involved. Breakdown in peripheral self-tolerance, and impaired functions of FOXP3+ regulatory T cell along with effector cell resistance to suppression at the tissue level seem to play an important role in AIH immunopathogenesis. …”
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NUCB2/Nesfatin-1 Regulation of Chronic Visceral Hyperalgesia by Qiaoyan Gu, Yuan Lei, Jianming Wu, Ting He, Juanjuan Li, Shanshan Song

“…NUCB2/Nesfatin-1 could regulate visceral sensitivity in chronic visceral hyperalgesia model rats; its regulatory effect correlated with the type of NUCB2/Nesfatin-1 intervention approaches (central or peripheral) and sex (male or female).…”
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Effect of adjacent structures on footing settlement for different multi-building arrangements by Chandrawanshi Shrish, Garg Vivek

“…The results indicate that in SSI case, inner footings show greater settlement compared to peripheral footings which causes high value of differential settlement between peripheral footings and those immediately adjacent to them. …”
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Influence of Lidocaine including Buprenorphine for Postoperative Analgesia after the Extraction of Mandibular Third Molars: A Randomized Controlled, Double-Blind, Split-Mouth Study by Nimrat K. Jawanda, Anand Shukla, Anupam Singh, Kalyana C. Pentapati, Srikanth Gadicherla

“…Studies have also reported the efficacy of peripherally administered opioids in achieving adequate analgesia in regions with inflammation. …”
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Atypical Vascular Involvement in a Case of Behçet's Disease by Alejandro Rodríguez Morata, Ana Hidalgo Conde, Carlos de la Cruz Cosme, Susana Gómez Ramírez, Rafael Gómez Medialdea

“…We present a case of a young male with atypical BD and severe polyvascular involvement (previous cerebral venous thrombosis and current peripheral venous thrombosis, acute ischemia, and peripheral arterial pseudoaneurysm) who required urgent surgical intervention due to a symptomatic external iliac pseudoaneurysm. …”
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