Factors associated with the formation of neutralizing antibodies post-vaccination: a lesson from COVID-19 vaccination by Hana Ratnawati, Fen Tih, Grace Puspasari, Allen A. Pelapelapon, Steven Felim

“…Methods: A cross-sectional study was conducted among mass vaccination attendees using inactivated CoronaVac. Collected the peripheral blood serum four weeks following the second vaccine dose. …”
Get full text

Serum Alkaline Phosphatase in Free-Ranging Male Moose Alces alces (Linnaeus 1758) of Different Age Groups by Maria A. Perevozchikova, Igor A. Domsky, Yulia A. Berezina, Professor Zhitkov Russian Research Institute of Game Management and Fur Farming, Kirov, Russia, Alexandr V. Economov

“…The moose has good prospects for hunting and game breeding. Peripheral blood indicators can provide information about their health status and adaptive capabilities, as well as non-infectious, infectious, and invasive pathologies. …”
Get full text

A Circulating Subpopulation of Monocytic Myeloid-Derived Suppressor Cells as an Independent Prognostic/Predictive Factor in Untreated Non-Small Lung Cancer Patients by Eleni-Kyriaki Vetsika, Filippos Koinis, Marianthi Gioulbasani, Despoina Aggouraki, Anna Koutoulaki, Eirini Skalidaki, Dimitris Mavroudis, Vassilis Georgoulias, Athanasios Kotsakis

“…The percentages and correlation between MDSCs and distinct immune cells in the peripheral blood of 110 chemotherapy-naive patients before treatment and healthy controls were investigated using flow cytometry. …”
Get full text

Combining systemic inflammation biomarkers with traditional prognostic factors to predict surgical site infections in elderly hip fracture patients: a risk factor analysis and dyna... by Yuhui Guo, Chengsi Li, Haichuan Guo, Peiyuan Wang, Xuebin Zhang

“…Biomarkers were calculated from peripheral venous blood collected on admission. The Centers for Disease Control and Prevention (CDC) definition of SSI was applied, with SSI identified through medical and pathogen culture records during hospitalization and routine postoperative telephone follow-ups. …”
Get full text

Effect of Therapeutic Inhibition of TNF on Circulating Endothelial Progenitor Cells in Patients with Rheumatoid Arthritis by F. R. Spinelli, A. Metere, C. Barbati, M. Pierdominici, C. Iannuccelli, B. Lucchino, F. Ciciarello, L. Agati, G. Valesini, M. Di Franco

“…EPCs were identified from peripheral blood mononuclear cells by cytofluorimetry using anti-CD34 and anti-vascular endothelial growth factor-receptor 2. …”
Get full text

Infiltration of Blood-Derived Macrophages Contributes to the Development of Diabetic Neuropathy by Jing-Jing Sun, Lin Tang, Xiao-Pei Zhao, Jun-Mei Xu, Yang Xiao, Hui Li

“…Further analysis by flow cytometry showed that the infiltration of peripheral macrophages began to increase in 2 weeks (P<0.001) and reached a maximum at 4 weeks (P<0.001) post-STZ injection compared to the control. …”
Get full text

Very Small Embryonic-Like Stem Cells, Endothelial Progenitor Cells, and Different Monocyte Subsets Are Effectively Mobilized in Acute Lymphoblastic Leukemia Patients after G-CSF Tr... by Andrzej Eljaszewicz, Lukasz Bolkun, Kamil Grubczak, Malgorzata Rusak, Tomasz Wasiluk, Milena Dabrowska, Piotr Radziwon, Wojciech Marlicz, Karol Kamiński, Janusz Kloczko, Marcin Moniuszko

“…We used multicolor flow cytometry to quantitate numbers of CD34+ cells, hematopoietic stem cells (HSCs), VSELs, EPCs, and different monocyte subsets in the peripheral blood of ALL patients and normal age-matched blood donors. …”
Get full text

Patient-reported symptoms and admission pathways in stroke mimics versus confirmed stroke or transient ischaemic attack: a cross-sectional observational study by Jawad Haider Butt, Christina Kruuse, Heidi Shil Eddelien, Viktor Frederik Idin Sørensen

“…Secondarily, the number of strokes versus mimics presenting at a healthcare facility within 3 hours contacted the emergency medical service (EMS) and arrived by ambulance.Results Of 592 suspected patients with stroke, 113 (19.1%) were mimics; most frequently peripheral vertigo (24.7%) and migraine (11.5%). Factors associated with a higher likelihood of mimics were female sex (OR 1.79, 95% CI 1.14 to 2.79), high Scandinavian Stroke Scale scores (OR 1.05, 95% CI 1.02 to 1.09, per point increase), and vertigo (OR 1.86, 95% CI 1.18 to 2.95). …”
Get full text

High CD163 Expression on Classical Monocytes Is Associated with Immune Control of HBV Infection in Noncirrhotic Patients by Anna Parfieniuk-Kowerda, Kamil Grubczak, Andrzej Eljaszewicz, Magdalena Świderska, Magdalena Maciaszek, Anatol Panasiuk, Jerzy Jaroszewicz, Robert Flisiak, Marcin Moniuszko

“…The control group consisted of 15 healthy volunteers. Subpopulations of peripheral blood monocytes were distinguished by CD14 and CD16. …”
Get full text

Diagnostic Management and Surgical Treatment of Isolated Tricuspid Regurgitation by Arthur Cicupira Rodrigues de Assis, Gustavo Andre Boeing Boros, Lea Maria Macruz Ferreira Demarchi, Thiago Luis Scudeler, Paulo Cury Rezende

“…Physical examination revealed a prominent bilateral jugular turgescence, hepatomegaly, peripheral edema, and a left midsternal border holosystolic murmur, suggestive of tricuspid regurgitation. …”
Get full text

IgG4 as a Biomarker in Graves’ Orbitopathy by Michał Olejarz, Ewelina Szczepanek-Parulska, Daniela Dadej, Nadia Sawicka-Gutaj, Remigiusz Domin, Marek Ruchała

“…Characteristic features of GD with elevated IgG4 levels include lower echogenicity of the thyroid gland on ultrasound examination, peripheral blood eosinophilia, higher prevalence of orbitopathy, and better response to antithyroid drugs with a tendency to develop hypothyroidism when compared to patients with GD and normal levels of IgG4. …”
Get full text

Circulatory Immune Cells in Cushing Syndrome: Bystanders or Active Contributors to Atherometabolic Injury? A Study of Adhesion and Activation of Cell Surface Markers by Gloria Aranda, Cristina Lopez, Rebeca Fernandez-Ruiz, Yaiza Esteban, Guillermo Garcia-Eguren, Mireia Mora, Irene Halperin, Gregori Casals, Joaquim Enseñat, Felicia A. Hanzu

“…To investigate adhesion and activation surface cell markers (CDs) of peripheral IMNC in endogenous Cushing syndrome (CS) and the immune modulator role of ACTH. …”
Get full text

Intravenous Transplantation of Mesenchymal Stem Cells Reduces the Number of Infiltrated Ly6C+ Cells but Enhances the Proportions Positive for BDNF, TNF-1α, and IL-1β in the Infarct... by Yunqian Guan, Xiaobo Li, Wenxiu Yu, Zhaohui Liang, Min Huang, Renchao Zhao, Chunsong Zhao, Yao Liu, Haiqiang Zou, Yanli Hao, Zhiguo Chen

“…The resident microglial and infiltrating cells from peripheral circulation are involved in the pathological processes of ischemia stroke and may be regulated by mesenchymal stem/stromal cell (MSC) transplantation. …”
Get full text

A multicenter study of neurofibromatosis type 1 utilizing deep learning for whole body tumor identification by Cheng-Jiang Wei, Yan Tang, Yang-Bai Sun, Tie-Long Yang, Cheng Yan, Hui Liu, Jun Liu, Jing-Ning Huang, Ming-Han Wang, Zhen-Wei Yao, Ji-Long Yang, Zhi-Chao Wang, Qing-Feng Li

“…Using neurofibromatosis type 1 (NF1) as an example, this study developed highly accurate MRI-based deep-learning models for the early automated screening of malignant peripheral nerve sheath tumors (MPNSTs) against complex whole-body background. …”
Get full text

Severe pregnancy-associated atypical hemolytic uremia syndrome in the context of the COVID-19 pandemic: a novel survival case report by Yan Yang, Xiao-jin Li, Hua-Yan Yuan, Jing-Jing Xiong, Peng-Fei Li, Zhen Wang

“…Although tests such as the ADAMTS13 level, peripheral blood smears, complement testing, and blood cultures are useful for diagnosing aHUS, these tests are time-consuming and may not be widely available. …”
Get full text

Circulating, Extracellular Vesicle-Associated Tissue Factor in Cancer Patients with and without Venous Thromboembolism by Valentina Lami, Dario Nieri, Marta Pagnini, Mario Gattini, Claudia Donati, Mariella De Santis, Alessandro Cipriano, Erica Bazzan, Andrea Sbrana, Alessandro Celi, Tommaso Neri

“…EV were isolated by differential centrifugation from 4 mL of peripheral blood; the final EV pellet (16,000× <i>g</i> for 45 min) was resuspended in 100 μL saline and tested for TF using a one-step clotting assay. …”
Get full text

Circulating Tumor DNA Detection for Recurrence Monitoring of Stage I Non‐Small Cell Lung Cancer Treated With Microwave Ablation by Lin Cheng, Sheng Xu, Yu‐feng Wang, Sheng‐wei Li, Bin Li, Xiao‐Guang Li

“…Methods We recruited 43 patients with inoperative stage I NSCLC, all of whom underwent biopsy‐synchronous microwave ablation (MWA). Peripheral blood samples were collected at baseline (n = 43), within 1 h post‐MWA (n = 28), and at the landmark time point (n = 26) for MRD detection. …”
Get full text

T-cell immune status in patients with acute exacerbation of chronic obstructive pulmonary disease: a case-control study by Xiao-feng Xiong, Xiao-feng Xiong, Min Zhu, Min Zhu, Hong-xia Wu, Zuo-hong Wu, Li-li Fan, De-yun Cheng

“…The distribution of T cell subsets in peripheral blood of AECOPD, SCOPD, and healthy controls (HCs) was measured using multi-color flow cytometry, and the functional status was analyzed by additional staining of activation markers.ResultsA total of 43 HCs, 43 SCOPD patients, and 64 AECOPD patients were evaluated. …”
Get full text

BAFF and APRIL immunotherapy following Bacille Calmette-Guérin vaccination enhances protection against pulmonary tuberculosis in mice by Min Xie, Chen-Yu Tsai, Joshua Woo, Frank Nuritdinov, Melissa Cristaldo, Narineh M. Odjourian, Rosleine Antilus-Sainte, Maureen Dougher, Martin Gengenbacher, Martin Gengenbacher

“…Both cytokines play overlapping roles in B cell development and peripheral survival. Following subcutaneous BCG vaccination, immunotherapy with BAFF or APRIL resulted in an increased frequency of unconventional B cells potentially transitioning into antibody-producing plasma cells. …”
Get full text

INTER-ILEAL-ABDOMINAL DISSECTION IN THE TREATMENT OF PATIENTS WITH LOCALLY ADVANCED BONY AND SOFT TISSUE SARCOMAS by V. A. Derzhavin, V. Yu. Karpenko, A. V. Bukharov, M. V. Ivanova

“…In 2 (7.5%) synovial sarcoma and in one (3.5%) malignant tumor from the shells of peripheral nerves. The primary tumor process was in 21 (81%) patients. …”
Get full text