Seasonal and Weather Effects on Rheumatoid Arthritis: Myth or Reality? by Hamida Azzouzi, Linda Ichchou

“…No significant associations were observed in the spring. Conclusion. Our study supported the physicians’ assumption regarding the effect of climate on pain in RA patients.…”
Get full text

The Human IL-22 Receptor Is Regulated through the Action of the Novel E3 Ligase Subunit FBXW12, Which Functions as an Epithelial Growth Suppressor by Joseph Franz, Jacob Jerome, Travis Lear, Qiaoke Gong, Nathaniel M. Weathington

“…To identify cellular factors that regulate human IL-22R, we screened receptor abundance while overexpressing constituents of the ubiquitin system and identify that IL-22R can be shuttled for degradation by multiple previously uncharacterized F-box protein E3 ligase subunits. We observe that in human cells IL-22R is destabilized by FBXW12. …”
Get full text

Rheumatoid Arthritis, Circulating Inflammatory Proteins, and Hypertension: A Mendelian Randomization Study by Guobing Jia, Tao Guo, Lei Liu, Chengshi He

“…ABSTRACT Observational studies have indicated that there is an association between rheumatoid arthritis (RA) and an elevated risk of hypertension. …”
Get full text

Mathematical Modeling of Tuberculosis Transmission Dynamics With Reinfection and Optimal Control by Francis Oketch Ochieng

“…The fitting algorithm yielded a mean absolute error (MAE) of 0.0069, demonstrating a close alignment between simulated and observed data. The optimized parameter values were used to project future TB dynamics. …”
Get full text

Influence Factors’ Analysis of the Face-End Roof Leaks Exposed to Repeated Mining Based on Multiple Linear Regression by Qiang Li, Dezhong Kong, Guiyi Wu, Zhijie Wen, Yuqi Shang

“…In view of the fact that the face-end roof fall under repeated mining of close-distance coal seams seriously affects the normal production of the working face, this paper takes working face 17101 as the background, different influencing factors of face-end roof caving exposed to repeated mining are analyzed through field observation of mine pressure data, different calculation schemes are obtained by using the orthogonal experiment, the subsidence of the face-end roof is taken as the judgment index, UDEC simulation software is used to calculate the subsidence of the face-end roof when different influencing factors change, and the application of SPSS statistical software is used for various parameters of multivariate linear regression analysis. …”
Get full text

A Study on Pattern of Retinal Detachment in Patients with Choroidal Coloboma and Its Outcome after Surgery at a Tertiary Eye Hospital in Nepal by Barsha Suwal, Govinda Paudyal, Raba Thapa, Sanyam Bajimaya, Sanjita Sharma, Eli Pradhan

“…To review the pattern of retinal detachment (RD) in patients with choroidal coloboma and type of reattachment surgery performed and to study its outcome in terms of retinal reattachment, visual acuity, and postsurgical complications. Methods. Observational case series of a single tertiary eye institution of 13 eyes having choroidal coloboma with RD done from January 2015 to June 2017. …”
Get full text

SARS-CoV-2 Genome-Based Severity Predictions Correspond to Lower qPCR Values and Higher Viral Load by Martin Skarzynski, Erin M. McAuley, Ezekiel J. Maier, Anthony C. Fries, Jameson D. Voss, Richard R. Chapleau

“…For those samples predicted to be “severe” (probability of severe illness >0.5), we observed an average cycle threshold (Ct) of 18.3, whereas those in in the “mild” category (severity probability <0.5) had an average Ct of 20.4 (P=0.0017). …”
Get full text

High Percentage of ADAM-10 Positive Melanoma Cells Correlates with Paucity of Tumor-Infiltrating Lymphocytes but Does Not Predict Prognosis in Cutaneous Melanoma Patients by Piotr Donizy, Marcin Zietek, Marek Leskiewicz, Agnieszka Halon, Rafal Matkowski

“…Also, prognostic significance of ADAM-10 expression in primary tumor cells and metastatic lesion cells was evaluated during 5-year observation. It was revealed that high expression of ADAM-10 positive cells was strictly related with lower intensity of tumor-infiltrating lymphocytes (P=0.037), which suggests that ADAM-10 regulates immunoresponse in melanoma initiation and progression. …”
Get full text

Application of Remote Sensing Image Data Scene Generation Method in Smart City by Yuanjin Xu

“…Remote sensing image simulation is a very effective method to verify the feasibility of sensor devices for ground observation. The key to remote sensing image application is that simultaneous interpreting of remote sensing images can make use of the different characteristics of different data, eliminate the redundancy and contradiction between different sensors, and improve the timeliness and reliability of remote sensing information extraction. …”
Get full text

Effect of Efavirenz on Endogenous Progesterone Concentrations and Contraceptive Outcomes among Ugandan HIV Infected Women Coadministering Ethinylestradiol/Levonorgestrel by Grant Munkwase, Kuteesa R. Bisaso, Othman Kakaire, Sarah Nanzigu

“…Based on serum endogenous progesterone, the observed hormonal contraceptives failure rate (24.5%) was higher than expected (maximum 8%). …”
Get full text

Clinical and Morphological Manifestations of Gastritis and Serum Cytokine Levels in Schoolchildren with Familial History of Gastric Cancer by T. V. Polivanova, E. V. Kasparov, V. A. Vshivkov

“…In histologically verified H. pylori, no cross-cohort differences were observed in serum IL-18 by positive familial history of gastric cancer.Conclusion. …”
Get full text

A Node Similarity and Community Link Strength-Based Community Discovery Algorithm by Haijuan Yang, Jianjun Cheng, Zeyi Yang, Handong Zhang, Wenbo Zhang, Ke Yang, Xiaoyun Chen

“…Inspired by these observations, we present a community-detection method named NSCLS in this paper. …”
Get full text

Clinical Utility of Zuranolone for Postpartum Depression: A Narrative Review by Giannopoulos A, Singh J, Deligiannidis KM

“…No clinically significant changes in vital signs, electrocardiogram or clinical lab parameters were observed. No loss of consciousness and no increase in suicidal ideation from baseline or deaths were seen in the studies. …”
Get full text

Role of HLA alleles polymorphism in systemic lupus erythematosus: A prospective study from North India by Ranjan S. Rana, Bitan Naik, Mahima Yadav, Usha Singh, Anup Singh, Shailja Singh

“…Materials and Methods: This was a prospective observational study, in which a total of 100 SLE patients and 100 controls were analyzed. …”
Get full text

Extraction approaches for the isolation of some POPs from lipid-based environmental and food matrices: A review by Carriera Fabiana, Di Fiore Cristina, Iannone Alessia, Maio Monica, Avino Pasquale

“…Despite the differences in the approaches used, the observed recoveries are high, >80%. Additionally, it was found that the same technique could extract different contaminants from various matrices, resulting in a loss of selectivity of the method used. …”
Get full text

The relationship of growth differentiation factor 15 with some biochemical parameters in cardiovascular disease patients in Babylon City by Hiba Resheed Behayaa, Zinah Abbass Ali, Seenaa Badr Mohammed, Suhayr A. Alqaysi

“…In contrast, the current study observed a non-significant (P > 0.05) association for GDF15 with all the clinical and biochemical parameters measured in this study. …”
Get full text

Assessment of Morphological Changes in Breast Cancer Cells Following X-Ray Radiation Utilizing Digital Holographic Microscopy by Zeinab Hormozi-Moghaddam, Seyedeh Mona Taheri, Reza Paydar, Ali Neshasteh-Riz, Vahideh Farzam Rad, Mohadeseh Shaghaghi

“…Results: The results indicate a significant increase in the morphological parameters of cells, encompassing volume, and roughness, subsequent to radiation exposure when contrasted with the control group. This observation signifies discernible alterations in the shape and roughness characteristics of MCF7 cells. …”
Get full text

Research on Integrated Control Strategy for Highway Merging Bottlenecks Based on Collaborative Multi-Agent Reinforcement Learning by Juan Du, Anshuang Yu, Hao Zhou, Qianli Jiang, Xueying Bai

“…By transforming the control framework into a Decentralized Partially Observable Markov Decision Process (Dec-POMDP), state and action spaces for heterogeneous agents are designed. …”
Get full text

Haemodynamic Effects of Anaemia in Patients with Acute Decompensated Heart Failure by Paweł Krzesiński, Agata Galas, Grzegorz Gielerak, Beata Uziębło-Życzkowska

“…Thoracic fluid content was higher (p=0.037) in anaemic subjects, while no significant relation between anaemia and NYHA was observed. Anaemic subjects with LVEF ≥ 40% were distinguished from those with LVEF < 40% by significantly higher stroke index (p=0.002), Heather index (p=0.014), and acceleration index (p=0.047). …”
Get full text

Effects of a 12-week digital training equipment program on cognitive function and mental health in older women: a randomized controlled trial by Byung-Sun Lee, Bong Du Choi, Ho Sung Park, Chae Won Seo, Kyung-Ae Kim

“…Interaction effects were observed in body fat mass ( P  = .011) and body fat percentage ( P  = .01), with improvements noted in the digital intervention group. …”
Get full text