Response to Aflibercept Therapy in Three Types of Choroidal Neovascular Membrane in Neovascular Age-Related Macular Degeneration: Real-Life Evidence in the Czech Republic by Jan Nemcansky, Alexandr Stepanov, Michal Koubek, Miroslav Veith, Yun Min Klimesova, Jan Studnicka

“…This was a multicentre, prospective, observational consecutive case series study. Patients diagnosed with three types of CNV of nAMD were treated in a fixed regimen (3 injections every 4 weeks, and then injections at 8 week intervals). …”
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Effects of mode of reproduction on genetic polymorphism and divergence in wild yams (Dioscoreaceae: Dioscorea) by Xin Wang, Qing-Hong Feng, Zhi-Hua Zeng, Zhi-Qiang Zhang, Jie Cai, Gao Chen, De-Zhu Li, Hong Wang, Wei Zhou

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The enigmatic diploid Chenopodium ucrainicum (Chenopodiaceae / Amaranthaceae s. l.): geographical, ecological, and phytosociological patterns as clues to its origin by Shynder O.I., Pashkevych N.A., Kharytonova I.P., Holovko O.V., Mandák B., Mosyakin S.L.

“…The distribution pattern indicates its primary occurrence in synanthropic environments with moderate moisture levels, and its presence in disturbed habitats suggests its likely status as an alien species in Ukraine. Observations also noted its high projective coverage in plant communities associated with Acer negundo and Robinia pseudoacacia, where C. ucrainicum, if present, frequently plays a dominant role among species of the herbaceous layer. …”
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The compensatory enrichment of sphingosine-1-phosphate on HDL in FSGS enhances the protective function of glomerular endothelial cells compared to MCD by Yunfeng Xiong, Qiuping Ye, Lifang Liu, Wanjun Lin, Yonggen Liao, Ruiyu Gao, Jiaming Xu, Xinyu Zhang, Ruoyan Chen, Sihui Chen, Qiaoling Chen, Lixin Wei

“…Additionally, the synthesis activity of S1P in renal tissues of FSGS patients was markedly higher than that observed in MCD patients and healthy controls, suggesting that S1P may play a crucial protective role in the progression of FSGS. …”
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Empowerment of Community Creative Economy Through the Islamic Education Assembly (Majelis Taklim) by Handayani Indah Susanti

“…The research adopts a qualitative approach, utilizing fieldwork through interviews, observations, and document analysis. The findings reveal that the empowerment process is carried out through a bottom-up approach based on the community's own initiatives. …”
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Association of genomic predictions for fertility traits with reproductive outcomes in dairy cows under 2 estrus detection and timed artificial insemination programs by D.B. Melo, R.G.S. Bruno, R.S. Bisinotto, F.S. Lima

“…Interactions between RepP and GDPR were present for TP1, AIE, and P1, but no interactions were observed between RepP and GCCR. The short program had a shorter interval from calving to pregnancy than the long program. …”
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Neuropsychiatric profile in tuberous sclerosis complex patients with epilepsy by Mahmoud Fawzi Osman, Mahmoud Fawzi Osman, Faisal Hadid, Tawfeg ben Omran, Tawfeg ben Omran, Tawfeg ben Omran, Munira Aden, Fatima Al-Maadid, Sondos Altaraqji, Khalid Mohamed, Ruba Benini, Ruba Benini

“…Significant correlations were observed between epilepsy severity and ASD-related domains, and the high prevalence of intellectual disability in TSC patients was highlighted. …”
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Co-infection of SARS‐CoV‐2 and influenza A/B among patients with COVID-19: a systematic review and meta-analysis by Monireh Golpour, Hossein Jalali, Reza Alizadeh-Navaei, Masoumeh Rezaei Talarposhti, Tahoora Mousavi, Ali Asghar Nadi Ghara

“…Significant heterogeneity was observed in the random-effects model for influenza A, 11% (95% CI: 5-18%) and B, 4% (95% CI: 2-7%) in co-infected patients. …”
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PGC-1α Promotes mitochondrial biosynthesis and energy metabolism of goose fatty liver by Jiahui Li, Mengqing Lv, Zijin Yuan, Jing Ge, Tuoyu Geng, Daoqing Gong, Minmeng Zhao

“…However, the mRNA expression levels of PGC-1β, SIRT5 and AMPKα were decreased after PGC-1α interference. Furthermore, we observed a significant increase in the mitochondrial DNA (mtDNA) copy number, the activity of mitochondrial respiratory chain complex Ⅳ (MRCC Ⅳ), succinate dehydrogenase (SDH), malate dehydrogenase (MDH), and the NAD+/NADH ratio in fatty liver. …”
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Hubungan Tingkat Pengetahuan dan Sikap dengan Tindakan Pencegahan Osteoporosis pada Wanita Usila di Kelurahan Jati by Sri Ganesh Rajaratenam, Rose Dinda Martini, Nur Indrawati Lipoeto

“…This study aimed to determine whether there is a relationship between the level of knowledge and attitudes with osteoporosis preventive measures.The study was an observational study with cross-sectional design. The study population was elderly women ≥ 60 years who reside in the Village of Jati, East Padang district. …”
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Green synthesis of nano-copper oxide using Sargassum sp. functionalized in cellulose acetate membrane for dye adsorption by U. Yanuhar, H. Suryanto, M. Amin, J.S. Binoj, I. Casuarina

“…Nano-copper oxide was introduced to bacterial acetate produced from pineapple peel waste to make a composite membrane and observed the antibacterial activity against E.coli and S.aureus, and dye adsorption to Methylene Blue, Malachite Green, Metanil Yellow, and Congo Red for 60 minutes contact time.FINDINGS: Nano-copper oxide is successfully synthesized using macroalgae Sargassum sp. proved by wavelength of ultra violet-visual spectroscopy results at 300 nanometer and energy dispersive spectroscopy analysis that denotes the presence of copper at 0.93 and 8.04 kilo electron volt. …”
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Investigating service delivery and perinatal outcomes during the low prevalence first year of COVID-19 in a multiethnic Australian population: a cohort study by Vincent W Lee, N Wah Cheung, Dharmintra Pasupathy, Sarah J Melov, James Elhindi, Therese M McGee, Seng Chai Chua, Justin McNab, Thushari I Alahakoon

“…Composite adverse neonatal outcomes were marginally higher (aOR 1.08; 95% CI 1.00 to 1.15, p=0.04) and full breastfeeding rates at hospital discharge reduced by 15% (aOR 0.85; 95% CI 0.80 to 0.90, p<0.001).Conclusion Despite a low prevalence of COVID-19, both positive and adverse obstetric outcomes were observed that may be related to changes in service delivery and interaction with healthcare providers. …”
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Alchornea cordifolia leaf-extract ameliorates bisphenol A-induced obesity in male Wistar rats by Abdulhakeem Rotimi Agboola, Ako Hogan Itam, Chinedum Martins Ekeleme, Eyuwa Ignatius Agwupuye, Zuwairatu Oyiza Ahmed, Godswill Peter Igiakong, Gideon Bassey Agbor, Asmau Niwoye Abubakar, Zainab Adamu, Esien David-Oku, Item Justin Atangwho

“…However, upon 4-week ACEE oral treatment at 500 and 1000 mg/kg b.w., there was observed significant attenuation of the anthropometric indices, serum biochemical indices and lipid metabolizing enzymes studied (p < 0.05). …”
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Disparate and shared transcriptomic signatures associated with cortical atrophy in genetic behavioral variant frontotemporal degeneration by Ting Shen, Jacob W. Vogel, Vivianna M. Van Deerlin, EunRan Suh, Laynie Dratch, Jeffrey S. Phillips, Lauren Massimo, Edward B. Lee, David J. Irwin, Corey T. McMillan

“…The different patterns of spatial correlations between synaptic density and cortical thinning, further confirmed the critical role of neurotransmission and synaptic signaling in shaping brain structure, especially in the GRN-bvFTD group. Furthermore, we observed significant overlap between genes linked to TDP-43 pathology and the gene sets associated with cortical thickness in C9orf72-bvFTD and GRN-bvFTD but not the MAPT-bvFTD group providing specificity for our associations. …”
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Time-restricted feeding improves metabolic syndrome by activating thermogenesis in brown adipose tissue and reducing inflammatory markers by Yueling Gong, Yueling Gong, Honghui Zhang, Jiang Feng, Li Ying, Mengmeng Ji, Shiyin Wei, Shiyin Wei, Qiming Ma

“…The study duration was 12 weeks. Key parameters observed included body weight, glucose tolerance (via glucose tolerance tests), insulin resistance (HOMA-IR), and insulin secretion under glucose stimulation. …”
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Comprehensive Analysis of m5C RNA Methylation Regulator Genes in Clear Cell Renal Cell Carcinoma by Jiajin Wu, Chao Hou, Yuhao Wang, Zhongyuan Wang, Pu Li, Zengjun Wang

“…Significantly better outcomes were observed in ccRCC patients in cluster 1 than in cluster 2. m5C RNA methylation-related risk score was calculated to evaluate the prognosis of ccRCC patients by seven screened m5C RNA methylation regulators (NOP2, NSUN2, NSUN3, NSUN4, NSUN5, TET2, and DNMT3B) in the training cohort. …”
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Safety and efficacy of CD33-targeted CAR-NK cell therapy for relapsed/refractory AML: preclinical evaluation and phase I trial by Ruihao Huang, Xiaoqi Wang, Hongju Yan, Xu Tan, Yingying Ma, Maihong Wang, Xiao Han, Jia Liu, Li Gao, Lei Gao, Guangjun Jing, Cheng Zhang, Qin Wen, Xi Zhang

“…No grade 3–4 adverse events were observed, except bone marrow suppression, which was relieved within one month. …”
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Optimization and Evaluation of Conditions for Orthotopic Nude Mouse Models of Human Liver Tumor Cells by MENG Yu, LIANG Dongli, ZHENG Linlin, ZHOU Yuanyuan, WANG Zhaoxia

“…On day 35 post-cell inoculation, mouse livers were dissected, and pathological slices were prepared for HE staining to observe histopathological changes in liver tissues. …”
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Beta-hydroxy-beta-methylbutyrate (HMB) improves daily activity and whole-body protein metabolism in Duchenne muscular dystrophy dogs: a pilot study by Peter P. Nghiem, Alexis M. Rutledge, Kyle Tehas, Corine Kaderli, Meredith Poling, Sidney Arnim, Vitaliy Dernov, Celine van Sas, Macie L. Mackey, Gabriella A. M. ten Have, Mariëlle P. K. J. Engelen, Nicolaas E. P. Deutz

“…Creatine kinase was not statistically different between groups. We did not observe any adverse clinical or biochemical-related effects of HMB dosing. …”
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Effect of sun dry brewer spent yeast on chemical composition, in vitro digestibility, and ruminal degradation kinetics of wheat straw by Geberemariyam Terefe, Mulugeta Walelgne, Dereje Fekadu, Getu Kitaw, Mesfin Dejene, Aeimro Kehaliu, Bethlehem Mekonnen, Yohannse Habteyesus

“…Results The highest ash, metabolizable energy, estimated digestible CP, DOMD, CP, Ca, P, Cu, Zn contents and the better DM, NDF, and CP ruminal degradability, and the lowest (P < 0.01) crude fibre, acid detergent fibre, NDF, K & Fe contents were observed in DBSY50 than the other DBSY inclusion level. …”
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