Revealing the heterogeneity of treatment resistance in less‐defined subtype diffuse large B cell lymphoma patients by integrating programmed cell death patterns and liquid biopsy by Wei Hua, Jie Liu, Yue Li, Hua Yin, Hao‐Rui Shen, Jia‐Zhu Wu, Yi‐Lin Kong, Bi‐Hui Pan, Jun‐Heng Liang, Li Wang, Jian‐Yong Li, Rui Gao, Jin‐Hua Liang, Wei Xu

“…Following this, we established a Programmed Cell Death Index (PCDI) utilizing the aforementioned genes and amalgamated it with pertinent clinical characteristics to formulate a predictive nomogram model for prognosis. We observed a significant correlation between the PCDI, pre‐treatment circulating tumour DNA (ctDNA) burden, minimal residual disease (MRD) status and immune features. …”
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Assessing the Impact of Climate Change on the Landscape Stability in the Mediterranean World Heritage Site Based on Multi-Sourced Remote Sensing Data: A Case Study of the Causses a... by Mingzhuo Zhu, Daoye Zhu, Min Huang, Daohong Gong, Shun Li, Yu Xia, Hui Lin, Orhan Altan

“…The results demonstrated that (1) the climate showed a warming and drying pattern during the study period, with distinct climate characteristics in different zones. (2) The dominance of woodland decreased (area proportion dropped from 76% to 66.5%); transitions primarily occurred among woodland, cropland, shrubland, and grasslands; landscape fragmentation intensified; and development towards diversification and uniformity was observed. (3) Significant spatiotemporal differences in landscape stability within the heritage site were noted, with an overall downward trend. (4) Precipitation had a high contribution rate in factor detection, with the interactive enhancement effects between temperature and precipitation being the most prominent. …”
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Validation of the role of apolipoproteins in coronary artery disease patients with impaired kidney function for prognosis: a prospective cohort study in China by Zixiang Ye, Enmin Xie, Zhangyu Lin, Chenxi Song, Rui zhang, Haoyu Wang, Yongbao Zhang, Kefei Dou

“…Result During a median follow-up of 3.1 years, 324 MACE events were observed. Multivariable Cox regression analyses illustrated higher levels of ApoB and the ApoB/A1 ratio were significantly associated with increased MACE incidence (adjusted HR [95%CI] 1.668[1.044–2.666]; adjusted HR [95%CI] 2.231[1.409–3.533], respectively), while lower ApoA1 levels correlated with a higher risk (adjusted HR [95%CI] 0.505[0.326–0.782]). …”
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Experimental infection of wild boars (Sus scrofa) with Rickettsia rickettsii and evaluation of the transmission potential to Amblyomma sculptum ticks by Lucianne Cardoso Neves, Lina de Campos Binder, Warley Vieira de Freitas Paula, Nicolas Jalowitzki de Lima, Ennya Rafaella Neves Cardoso, Rayane Almeida Santos, Raphaela Bueno Mendes Bittencourt, Gracielle Teles Pádua, Gabriel Cândido dos Santos, Mariana Avelar Tavares, Maria Carolina de Azevedo Serpa, Adriano Pinter, Artur Luiz de Almeida Felicio, Marcelo B. Labruna, Felipe da Silva Krawczak

“…Moreover, no disease or seroconversion was observed in guinea pigs and rabbits that were infested with ticks originated from wild boar acquisition feeding. …”
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Association between plasma perfluoroalkyl substances and high-grade serous ovarian cancer overall survival: A nested case-control study by Wei-Yi Xing, Fang-Hua Liu, Dong-Dong Wang, Jia-Ming Liu, Wen-Rui Zheng, Jia-Xin Liu, Lang Wu, Yue-Yang Zhao, He-Li Xu, Yi-Zi Li, Yi-Fan Wei, Dong-Hui Huang, Xiao-Ying Li, Song Gao, Qi-Peng Ma, Ting-Ting Gong, Qi-Jun Wu

“…Result: In full-adjusted model, significant differences were observed between HGSOC survival and perfluorobutane sulfonic acid, PFHpA, PFHxS, PFOS, PFCA, and PFSA. …”
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Earth–lunar thermal effect on the temperature stability of TianQin telescope and the suppression methods by Wenbo Chang, Yuxiang Wang, Wenhai Tan, Guanhua Wu, Houyuan Chen, Wei Li, Zizheng Li, Fan Zhu, Zhu Li, Xuefeng Zhang, Shanqing Yang

“…Besides the solar thermal irradiation, the earth and lunar heat irradiation exist in the TianQin orbit, and may enter the telescope during the observation period. Up to now, the effect of earth–lunar heat flux on the temperature stability of the TianQin telescope has not been addressed. …”
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A prospective randomized controlled trial comparing biphasic cartilage repair implant with microfracture in small chondral lesions of knee: findings at five-year-follow-up by Yao-Yi Kuo, Si-Qi Chiu, Wen-Pei Chang, Chih-Yu Chen, Chih-Hwa Chen, Chen-Kun Liaw, Cheng-Aun Tan, Pei-Wei Weng

“…Primary outcome measures included the International Knee Documentation Committee (IKDC) score, Knee Injury and Osteoarthritis Outcome Score (KOOS), Visual Analog Scale (VAS) score, Magnetic Resonance Imaging (MRI) measured cartilage thickness, and the Magnetic Resonance Observation of Cartilage Repair Tissue (MOCART) score. …”
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Effects of two kinds of vestibular function training on reducing motion sickness in college students by Linyao Shi, Jing Zhao, Jiamei Lu, Chuanxia Cao, Qikun Zhang, Chuanjing Qiu, Zhanguo Jin, Shengguang Yan, Shengguang Yan, Shengguang Yan

“…In the visual-motion cage rotating chair group, in addition to a reduction in the percentage of adjacent normal-to-normal intervals which differed by more than 50 ms (pNN50), as well as decreases in low-frequency power (LF), an increase in LF/HF was observed. Between-group comparisons showed that the Graybiel scores in the electric rotating chair group were better than those in the visual-motion cage rotating chair group. …”
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Comparison of ultrasonographic features between two types of hepatic echinococcosis and hepatoblastoma in children by Yi Tao, Hanqing Kong, Jiawu Li, Zhizhi Tan, Jun Wang, Yan Luo

“…Significant differences were observed in age and history of residence or travel to endemic areas among children with hepatic echinococcosis and hepatoblastoma (P < 0.001). …”
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The clinical utility of tissue polymerase chain reaction, tissue culture and tissue histology in blood culture-negative infective endocarditis in South Africa – insights from the G... by W Endres, P Mkoko, M Ntsekhe

“…We analysed data from the Groote Schuur Hospital (GSH) Infective Endocarditis Registry, a prospective observational study of adult patients with infective endocarditis. …”
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αAsarone alleviates neuronal injury by facilitating autophagy via miR-499-5p/PDCD4/ATG5 signaling pathway in ischemia stroke by Yonghuan Yan, Linfang Wu, Lu Wang, Dandan Wang, Mengting Huang, Jinyong Peng, Jinyong Peng, Yingying Huang, Yingying Huang, Yingying Huang

“…To further clarify the protective effect of αAsarone in vivo, TTC staining, neurological function score, H&E staining, Nissl staining, Laser speckle contrast imaging, transmission electron microscopy, immunofluorescence colocalization, WB and RT-qPCR were performed in the MCAO mice.ResultsαAsarone was observed to inhibit the apoptosis of neuronal cells, and enhance autophagy. …”
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Integrated physiological and transcriptomic analysis uncovers the mechanism of moderate nitrogen application on promoting the growth and (-)-borneol accumulation of Blumea balsamif... by Yuan Yuan, Wei-Jie Tang, Wei-Jie Tang, Jia-Yuan Cao, Ke Zhong, Ke Zhong, Ze-Jun Mo, Ying Zhou, Yu-Xin Pang, Yu-Xin Pang

“…Under the N1 treatment, the leaves harvested in October, November, and December exhibited the highest accumulation of (-)-borneol, with yields of 782 mg plant-1, 1102 mg plant-1, and 1774 mg plant-1, respectively, which were significantly different from those observed in the CK and N2 treatments. Comparative transcriptome analysis revealed a total of 6,714 differentially expressed genes (DEGs). …”
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Efficacy and Safety of Dual Antiplatelet Therapy in Patients Undergoing Coronary Stent Implantation: A Systematic Review and Network Meta-Analysis by Yi Xu, Yimin Shen, Delong Chen, Pengfei Zhao, Jun Jiang

“…No significant difference in all-cause mortality and cardiac death was observed. In patients with acute coronary syndrome, DAPT 6Mo was comparable to DAPT 12Mo. …”
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Kinetic Analysis of the Reduction Processes of a Cisplatin Pt(IV) Prodrug by Mesna, Thioglycolic Acid, and Thiolactic Acid by Yanqing Xia, Hongwu Tian, Yanlei Li, Xinru Yang, Jinming Liu, Chunli Liu, Li Zhou, Lincai Zhang, Tiejian Li, Tiesheng Shi

“…The reduction processes were followed under pseudo-first-order conditions and were found to strictly obey overall second-order kinetics; the observed second-order rate constant k′ versus pH profiles were established in a wide pH range. …”
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Effects of Environmental Factors on Carbon Stocks of Dry Evergreen Afromontane Forests of the Choke Mountain Ecosystem, Northwestern Ethiopia by Fikirte Asrat, Teshome Soromessa, Tesefaye Bekele, Rama Mohan Kurakalva, Sravya Sai Guddeti, David Russel Smart, Kristine Steger

“…In each forest, eight distinct aspect facings were observed, with the western (W) aspect containing the highest value of total carbon stock in both forests. …”
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Effect of Planting Systems on the Physicochemical Properties and Bioactivities of Strawberry Polysaccharides by Qiuqiu Zhang, Renshuai Huang, Guangjing Chen, Fen Guo, Yan Hu

“…A higher extraction yield was observed for EP-SP (5.88%) than for GP-SP (4.67%), and slightly higher values were measured for the average molecular weight (632.10 kDa vs. 611.88 kDa) and total sugar content (39.38% vs. 34.92%) in EP-SP. …”
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Hypothermia during Surgical Treatment of Type A Aortic Dissection: A 16 Years’ Experience by Francesco Macrina, Maria Cristina Acconcia, Luigi Tritapepe, Mizar D’abramo, Wael Saade, Alessandra Capelli, Fabio Miraldi

“…This is a retrospective observational study, and we examined 16-year trends in the presentation, diagnosis, hospital outcome and treatment of A AAD type. …”
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Incidence and predictors of seizure-related injuries among epileptic patients undergoing follow-up treatment at public hospitals in Central Ethiopia by Selamawit Wondale Begizew, Bethelhem Birhanu Muluneh, Taye Mezgebu Ashine, Asnakech Zekiwos Heliso, Getachew Ossabo Babore, Elias Ezo Ereta, Sentayehu Admasu Saliya, Awoke Girma Hailu, Elias Nigusu Abdisa

“…The incidence density rate of seizure-related injuries among epileptic patients was 11.97 per 100 person-months of observation (95% CI 10.61, 13.50). In multivariate analysis, epileptic patients who had generalized tonic–clonic seizures (adjusted hazard ratio 1.4, 95% CI 1.07–1.84), comorbidities (adjusted hazard ratio 1.3, 95% CI 1.11–1.71), were on polytherapy drug regimens (adjusted hazard ratio 1.80, 95% CI 0.30–2.49), and consumed alcoholic drinks (adjusted hazard ratio 1.5, 95% CI 1.21–1.89) were identified as independent predictors of seizure-related injuries. …”
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Dairy cows' responses to 2 separation methods after 3 months of cow-calf contact by Anina Vogt, Susanne Waiblinger, Rupert Palme, Uta König von Borstel, Kerstin Barth

“…Vocalizations and searching behavior were observed on 4 d/wk from 1 wk before separation until 1 wk after total separation. …”
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The Differential Expressions and Associations of Intracellular and Extracellular GRP78/Bip with Disease Activity and Progression in Rheumatoid Arthritis by Guoyin Liu, Jianping Wu, Yongqiang Wang, Yuansheng Xu, Chun Xu, Guilin Fang, Xin Li, Jianmin Chen

“…Nonetheless, a negative correlation was observed between GRP78/Bip levels and the stage of RA in SF, while positive correlations with the levels of TNF-α and IL-10 persisted. …”
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