Development and feasibility testing of a new device for home-based leg heat therapy in patients with lower extremity peripheral artery disease by Bohyun Ro, MSc, John P. Spence, BBA, Paul A. Spence, MD, Christian Buckley, BS, Raghu L. Motaganahalli, MD, Bruno T. Roseguini, PhD

“…Improvements were also observed in self-reported walking speed and quality of life. …”
Get full text

Aberrant B cell receptor signaling responses in circulating double-negative 2 B cells from radiographic axial spondyloarthritis patients by Rick Wilbrink, Stefan F.H. Neys, Rudi W. Hendriks, Anneke Spoorenberg, Frans G.M. Kroese, Odilia B.J. Corneth, Gwenny M.P.J. Verstappen

“…Enhanced BCR signaling responses were also observed in the transitional and naïve B cell population from r-axSpA patients compared with HCs. …”
Get full text

A novel model-based meta-analysis to indirectly estimate the comparative efficacy of two medications: an example using DPP-4 inhibitors, sitagliptin and linagliptin, in treatment o... by Yan Gong, James Rogers, Christian Friedrich, Sanjay Patel, Alexander Staab, Jorge Luiz Gross, Daniel Polhamus, William Gillespie, Brigitta Ursula Monz, Silke Retlich

“…For the indirect comparison, a population of 1000 patients was simulated from the model with a racial composition reflecting the average racial distribution of the linagliptin trials, and baseline HbA1c of 8%.Results The model was developed using longitudinal data from 11 234 patients (10 linagliptin, 15 sitagliptin trials), and assessed by internal evaluation techniques, demonstrating that the model adequately described the observations. Simulations showed both linagliptin 5 mg and sitagliptin 100 mg reduced HbA1c by 0.81% (placebo-adjusted) at week 24. …”
Get full text

Cross-Platform Ecological Momentary Assessment App (JTrack-EMA+): Development and Usability Study by Mehran Sahandi Far, Jona M Fischer, Svea Senge, Robin Rathmakers, Thomas Meissner, Dominik Schneble, Mamaka Narava, Simon B Eickhoff, Juergen Dukart

“… BackgroundTraditional in-clinic methods of collecting self-reported information are costly, time-consuming, subjective, and often limited in the quality and quantity of observation. However, smartphone-based ecological momentary assessments (EMAs) provide complementary information to in-clinic visits by collecting real-time, frequent, and longitudinal data that are ecologically valid. …”
Get full text

Impacts of Legacy and Contemporary Nitrogen Inputs on N2O and CO2 Emissions in Miscanthus and Maize Cultivated Soils by Jaejin Lee, Paul Villanueva, Kate Glanville, Andy Vanloocke, Wendy H. Yang, Angela Kent, Marshall McDaniel, Steven J. Hall, Adina Howe

“…A 150‐day soil incubation experiment was conducted using soils from a long‐term M×g and maize fertility experiment with three historic N fertilization rates (0, 112, and 336 kg N ha−1 year−1) and a contemporary amendment (60 mg N kg−1) with negative control (0 mg N kg−1). We observed significant increases in cumulative N2O emissions in Mxg soils relative to maize soils, particularly at higher legacy fertilization rates, while contemporary N had no significant effect. …”
Get full text

Bibliometric analysis of the impact of environmental degradation on women and the importance of women’s representation by Y.A. Pratama, M.Y.A. Kadir, A. Rivaldi, I.C. Mulya, S. Amirah, M. Iqhrammullah

“…This aspect is particularly important with a setback observed in the environmental management regulations in Indonesia, where the government ratified the Omnibus Law on Job Creation, which removes the stringent licensing process for environmentally impactful activities. …”
Get full text

Historical snow measurements in the central and southern Apennine Mountains: climatology, variability, and trend by V. Capozzi, F. Serrapica, A. Rocco, C. Annella, C. Annella, G. Budillon

“…To pursue this aim, we used the monthly observations of the snow cover duration, number of days with snowfall and total height of new snow collected at 129 stations located between 288 and 1750 m above sea level. …”
Get full text

Exploring the relationship between established HIV risk factors and depressive symptoms amongst young women without HIV in two sites in South Africa. by Zanenhlanhla Gumbi, Celia Mehou-Loko, Lindi Masson, Makhosazana Mdladla, Nokuthula Maphumulo, Jo-Ann Passmore, Sanele Mbeje, Linda Gail Bekker, Disebo Potloane, Heather Jaspan, Nina Radzey, Andrea Abrahams, Rushil Harryparsad, Pamela Mkhize, Hilton Humphries

“…Longitudinal studies are required to test the causal relationship between depression and HIV acquisition and to better understand the geospatial differences observed.…”
Get full text

An exploratory study of serum creatine kinase as a prognostic marker for patients with resectable pancreatic cancer: looking into the relationship with body composition by Cong Chen, Xin Luo, Xianchao Lin, Ronggui Lin, Yuanyuan Yang, Congfei Wang, Haizong Fang, Tianhong Teng, Heguang Huang, Fengchun Lu

“…Correlation analysis revealed a significant association between SMA and CK levels in male patients (r = 0.225, P = 0.025), and such a correlation was not observed in female patients (r = 0.088, P = 0.478). …”
Get full text

KAJIAN DESAIN LANSKAP KORIDOR JALAN DAGO BERDASARKAN PERSEPSI MASYARAKAT DALAM MENDUKUNG CITY BRANDING KOTA BANDUNG by Kusriantari Fenny Aprillia, Estuti Rochimah, Estuti Rochimah

“…The methodology used is descriptive quantitative, then data collection by site observation and questionnaire. The result is, the revitalization gives a positive image to the city and presents Paris Van Java. …”
Get full text

Insights into salinity effect on growth of the spotted scat (Scatophagus argus): Exploring the optimum salinity for its culture by Maoliang Su, Zhanquan Feng, Youling Zhong, Zhiyin Ye, Junbin Zhang

“…However, significant contrasts were found in cortisol levels between these groups, and at each timepoint, its highest level was observed in 30 ppt salinity group. As for GH and IGF-I, their highest values were recorded at 15 ppt, rather than 30 ppt, from the fourth week to the end of experimental period. …”
Get full text

Major Adverse Cardiovascular Events in Primary Aldosteronism After Adrenalectomy or Mineralocorticoid Receptor Antagonist Treatment: A Systematic Review and Meta‐Analysis by Chien‐Wei Huang, Tse‐Ying Huang, Ya‐Fei Yang, Li‐Yang Chang, Yu‐Kang Tu, Vin‐Cent Wu, Jui‐Yi Chen

“…A curvilinear dose–response relationship between the posttreatment plasma renin activity and the MACE incidence was observed, with the lowest risks at plasma renin activity of 1.0 to 2.0 ng/mL per hour (Pnonlinearity<0.001). …”
Get full text

Empirical Analysis of the Impact of the Internet on Social Trust in Chinese Provinces during 2016-2020 by Li Zhengrong, Guo Mengyao, Wang Fang

“…Fourth, the "dual-sided" effect of online social networking, as observed in this study, is manifested in its deleterious impact on trust within established social circles while simultaneously exerting a constructive influence on trust in individuals outside one's immediate network, thereby exemplifying the role of the Internet as a double-edged sword, where its capacity to both enhance and undermine trust depends on the nature of the interaction and the context in which it occurs. …”
Get full text

University proceedings. Volga region. Natural sciences by O.V. Chernyshova, N.A. Kartavov, R.A. Ilyin, S.V. Titov

“…At the same time, we note that the reverse situation – introgression of S. suslicus genes into the genotype of the large ground squirrel, outside the boundaries of hybrid colonies, in single-species colonies of S. major, was not detected by us during the entire observation period (30 years). In general, such a development of the relationship between speckled and large ground squirrels in the sympatry zone, which has existed for 70 years on the territory of the right-bank Volga region, associated with the fixation of foreign genes in the genotypes of speckled ground squirrels, imposes a number of restrictions on the planned research. …”

Behavior of SD-OCT Detectable Hyperreflective Foci in Diabetic Macular Edema Patients after Therapy with Anti-VEGF Agents and Dexamethasone Implants by Anne Rübsam, Laura Wernecke, Saskia Rau, Dominika Pohlmann, Bert Müller, Oliver Zeitz, Antonia M. Joussen

“…Methods. A prospective, observational study on 59 eyes of 51 DME patients who were treated with antivascular endothelial growth factor (VEGF) therapy (VEGF group, n=40 eyes) or dexamethasone implant (DEX group, n=19). …”
Get full text

Association between moderate-to-vigorous physical activity trajectories and academic achievement in Chinese primary school children: a 3-year longitudinal study by Junyu Wang, Yong Yang, Jun Wu, Ting Xie, Xuejun Guo, Xun Yuan, Ting Li, Yu Zhang, Huiying Zhao, Jie Zhuang

“…Additionally, notable gender differences in MVPA trajectories were observed, and a positive association was found between favorable sports attitudes and improved academic achievement. …”
Get full text

Cell Morphology on Poly(methyl methacrylate) Microstructures as Function of Surface Energy by Matthias Katschnig, Boris Maroh, Natascha Andraschek, Sandra Schlögl, Ulrike Zefferer, Elisabeth Bock, Gerd Leitinger, Christa Trattnig, Maria Kaufmann, Werner Balika, Clemens Holzer, Ute Schäfer, Silke Patz

“…“Walls” appeared to promote significant cell elongation, whilst a lack of cell adhesion was observed on “cubes” with the lowest periodicity. Contact angle measurements on walls revealed enhanced surface energy anisotropy (55 mN/m max., 10 mN/m min.) causing a lengthwise spreading of the test liquid droplet, similar to cell elongation. …”
Get full text

Evaluasi User Experience Aplikasi “J-KOPI (Jember Kota Pintar)” Menggunakan Metode Survei Dengan User Experience Questionnaire Dan User Interview by Pradiptya Kahvi Sugiharto, Satrio Hadi Wijoyo, Mochamad Chandra Saputra

“…The J-KOPI application aims to become "SuperApps" that provides a variety of information and various community services integrated with the OPD (local government agency) of the Jember Regency Regional Government in one application. Based on observations and interviews with DISKOMINFO, it was found that there were several problems with the application that could reduce the quality of the user experience. …”
Get full text

Vaccination with Delta-PGM in the control of buffalo (Bubalus bubalis) brucellosis by Alfredo Sánchez-Villalobos, Leandro Salas, Hengelbert Fuenmayor, Omaira Contreras, Enmanuel Machado

“…The data were analyzed through Friedman’s non-parametric statistical test, allowing comparisons between the observed characters. Ninety animals (90) without vaccination were detected, belonging to groups G1 and G2, one being positive for brucellosis (1/90; 1.11%; p>0.05). …”
Get full text

Forecasting the Incidence of Mumps Based on the Baidu Index and Environmental Data in Yunnan, China: Deep Learning Model Study by Xin Xiong, Linghui Xiang, Litao Chang, Irene XY Wu, Shuzhen Deng

“…DNLM analysis revealed that the relative risks consistently increased with rising Baidu index values, while nonlinear associations between temperature and mumps incidence were observed. Among the 4 models, model IBE exhibited the best performance, achieving the coefficient of determination of 0.72, with mean absolute error, mean absolute percentage error, and root-mean-square error values of 0.33, 15.9%, and 0.43, respectively, in the test set. …”
Get full text