Dietary supplementation with Epimedium contributes to the improvement of hormone levels, gut microbiota, and serum metabolite composition in the Chinese forest musk deer (Moschus b... by Shan Xie, Shan Xie, Qinlin Yang, Zaixiang Ying, Zaixiang Ying, Mingcheng Cai, Wenqiao Fan, Hanyu Gao, Hanyu Gao, Xiaolan Feng, Yongjiang Wu

“…Significant alterations were observed in key metabolic pathways related to lipid metabolism, hormone regulation, and antioxidation, such as ovarian steroidogenesis, tyrosine metabolism, and glycerophospholipid metabolism. …”
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Serum metabolic profiles in quails: Effects of age, breed, and sex by Qin He, Hanle Shang, Yizhong Huang, Lizhi Li, Zhuomin Wu, Huihui Ran, Jiguo Xu, Xinwei Xiong

“…Differences in energy metabolism and amino acid biosynthesis and metabolism were observed between males and females. These findings enhance our understanding of the dynamic changes in quail serum metabolites influenced by various factors and address the knowledge gap regarding serum metabolic changes at different stages in quails.…”
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Temperature, violent crime, climate change, and vulnerability factors in 44 United States cities by Seulkee Heo, Hayon Michelle Choi, Jesse D. Berman, Michelle L. Bell

“…Evidence is needed on daily impacts of temperature on crime, applying non-linear models across different locations. This observational study examined non-linear relationships between daily summer temperature (May–September) and violent crime in 44 cities across 33 US states, 2005–2022. …”
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CHANNELING: SEARCH OF THE METAANTHROPOLOGIC MEAS-UREMENTS OF MIND BEING IN THE UNIVERSE (based on the World Wide Web) by Anatoly T. Tshedrin

“…The features of channeling as cultural practices aimed at solving the problem of finding meta an-thropological dimensions of existence in the universe of the mind, as an attempt to resolve the contradiction between the theoretical ideas about extraterrestrial civilizations and the lack of empirically observable, the expected signs of their activities. …”
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The criteria for choice of myocardial revascularization method in patients with stable coronary artery disease in routine clinical practice by O.A. Yepanchintseva, O.J. Zharinov, K.O. Mikhaliev, A.V. Khokhlov, B.M. Todurov

“…We performed retrospective observational single-center study and analyzed data from the patients with stable CAD (n = 341), suitable for both methods of MR – percutaneous coronary intervention (PCI) or coronary artery bypass grafting (CABG), according to the pre-specified anatomical criteria. …”
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Enhancing Soil Moisture Prediction in Drought-Prone Agricultural Regions Using Remote Sensing and Machine Learning Approaches by Xizhuoma Zha, Shaofeng Jia, Yan Han, Wenbin Zhu, Aifeng Lv

“…Singular spectrum analysis (SSA) was first applied to reconstruct site-specific time series, filling in missing and singular values. Leveraging observational data from 617 monitoring sites across the North China Plain and multiple spatial covariates, we developed a machine learning model to estimate near-surface soil moisture at a 1 km resolution. …”
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Cardiovascular Risk Biomarkers in Women with and Without Polycystic Ovary Syndrome by Manjula Nandakumar, Priya Das, Thozhukat Sathyapalan, Alexandra E. Butler, Stephen L. Atkin

“…TF and renin upregulation observed in the BMI- and IR-matched limited sample PCOS subgroup indicates their potential risk of CVD.…”
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Disproportionality analysis of upadacitinib-related adverse events in inflammatory bowel disease using the FDA adverse event reporting system by Shiyi Wang, Xiaojian Wang, Jing Ding, Xudong Zhang, Hongmei Zhu, Yihong Fan, Changbo Sun

“…The median onset time for AEs related to upadacitinib was 41.00 days (interquartile range [IQR] 10–141.5 days), with the majority occurring within 3 months of treatment initiation (n = 269, 66.09%), particularly in the first month (n = 171, 42.01%).ConclusionOur findings affirm clinical observations and reveal potential new AE signals for upadacitinib, underscoring the need for prospective clinical studies to verify these results and clarify their clinical relevance. …”
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Is There a Noninvasive Source of MSCs Isolated with GMP Methods with Better Osteogenic Potential? by Carla C. G. Pinheiro, Alessander Leyendecker Junior, Daniela Y. S. Tanikawa, José Ricardo Muniz Ferreira, Reza Jarrahy, Daniela F. Bueno

“…These results suggest that deciduous dental pulp and orbicularis oris muscle stem cells demonstrate superior osteogenic differentiation potential relative to umbilical cord-derived stem cells and that this increased potential is related to their neural crest origins. Based on these observations, and the distinct translational advantage of incorporating stem cells from noninvasive tissue sources into tissue engineering protocols, greater study of these specific cell lines in the setting of alveolar cleft repair is indicated.…”
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Genetic divergence of hot pepper lines (Capsicum spp.) in hybrid combinations by Šević Biljana, Cvikić Dejan, Slađana Savić, Tupajić Ivan, Ugirnović Milan, Bajagić Marija, Luković Kristina, Stojiljković Jelena

“…The number of fruits per plant (11.40-16.80) and the number of chambers (2) were consistent across hybrids, with no statistically significant differences observed. By comparing market-available varieties with hybrids, which are still limited in number, the results of this study highlight the superiority of hybrids for cultivation in greenhouse. …”
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Enhanced antitumor activity of combined hepatic arterial infusion chemotherapy with Lenvatinib and PD-1 inhibitors in unresectable hepatocellular carcinoma: a meta-analysis by Lingling Zhao, Cheng Xu, Jiewen Deng, Yang Ni

“…Superior PFS was also observed in the HAIC-L-P group, with an HR of 0.64 (95% CI: 0.55-0.75; p < 0.0001), and higher 1-year and 2-year PFS rates. …”
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Incidence of opportunistic infections and its predictors among HIV/AIDS patients on antiretroviral therapy in Gondar University Comprehensive and Specialized Hospital, Ethiopia by Mequanente Dagnaw, Haileab Fekadu, Adhanom Gebre Egziabher, Tesfaye Yesfue, Meera Indracanti, Alemu Tebeje

“…During the follow-up period, the overall incidence of opportunistic infections was 4.1 (95 percent CI 3.74 to 4.44) per 10,000 person-year observation, with a median of 57 months (IQR = 40–69 months). …”
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The Malayan Landscape Paintings by Sarena Abdullah, Yuen Beng Lee

“…Traveller artists who arrived in Malaya and Singapore during the 18th and 19th centuries illustrated various subject matters that they observed. The most common examples included tropical flora and fauna, various views and landscapes, British residences, and so on. …”
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Impact of subgingival periodontal treatment on systemic markers of inflammation in patients with metabolic syndrome: a systematic review of randomized clinical trials by Marie Chavez, Asshly Ramirez, Akram Hernández-Vásquez, Daniel Comandé, Diego Azañedo

“…Only Montero et al. reported on interleukin 1β and TNF-α, observing significant reductions at 3 months for interleukin 1β (0.9 pg/dl ± SE: 0.1 vs. 2.3 pg/dl ± SE: 0.5; p = 0.046) and TNF-α (6.4 pg/dl ± SE: 0.8 vs. 10.0 pg/dl ± SE: 2.3; p = 0.037).DiscussionThe evidence is limited by the small number of comparative RCTs. …”
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Prospect use of Phaleria macrocarpa to prevent motile aeromonad septicaemia disease in Patin Catfish Pangasianodon hypophthalmus by D. Wahjuningrum, S.L. Angka, W. Lesmanawati, . Sa’diyah, M. Yuhana

“…For seven days after infection the clinical signs and blood pictures were observed. The in vitro test indicated that PM had an antibacterial effect to A.hydrophila at the dosage of 6 g/l. …”
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Hospital in-reach family-centred social prescribing pilot for children with neurodisability: mixed methods evaluation with social return on investment analysis by Laura Gordon, Megan Hastry, Angela Bate, Katie Gordon, Emily Greaves, Simoni Dimitriadou, Tim Rapley, Anna Purna Basu

“…We undertook 22 qualitative observations of family/link worker interactions and 39 in-depth interviews with families, link workers and healthcare professionals. …”
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Levels of Cytokines (IL-1β, IL-2, IL-6, IL-8, TNF-α) and Trace Elements (Zn, Cu) in Breast Milk From Mothers of Preterm and Term Infants by Bilal Ustundag, Erdal Yilmaz, Yasar Dogan, Saadet Akarsu, Halit Canatan, Ihsan Halifeoglu, Gurkan Cikim, A. Denizmen Aygun

“…Similar trends were observed in milk from mothers of premature infants, but cytokine levels were significantly lower in colostrum compared to colostrum from mothers of mature infants (P<.01). …”
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Transplantation of mitochondria from human malignant tumor cells as a method of tumor growth formation in the lungs of laboratory animals by O. I. Kit, E. M. Frantsiyants, A. I. Shikhlyarova, I. V. Neskubina

“…Respiratory problems in mice with mitochondrial transplantation occurred between days 113 and 123, when a drop in body weight ≥ 25 % was observed. A uniform formation of tumor nodes together with an active filling of the lung space with blood was clearly visible on lung preparations of a Balb/c Nude male mouse after intravenous transplantation of mitochondria from the lung of a patient with non-keratinizing squamous cell carcinoma. …”
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Lipid-encapsulated gold nanoparticles: an advanced strategy for attenuating the inflammatory response in SARS-CoV-2 infection by Sanjeevram Dhandapani, Yujeong Ha, Rongbo Wang, Tae Woo Kwon, Ik-Hyun Cho, Yeon-Ju Kim

“…This effect was mitigated with KGS-NE oral administration, as observed through H&E and qRT-PCR analysis. Biochemical analysis at various oral administration concentrations demonstrated that KGS-NE had no adverse effects on the kidney and liver. …”
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Clinic evaluation of cognitive impairment in post-COVID syndrome: Performance on legacy pen-and-paper and new digital cognitive tests by Aysha Mohamed Rafik Patel, Gina Gilpin, Anna Koniotes, Catherine Warren, Cian Xu, Paul W. Burgess, Dennis Chan

“…The LCCAB detected cognitive impairments in nearly 90% of participants, primarily affecting attention, executive function, and processing speed. These observations highlight the need for alternative cognitive tests for use in routine clinical practice to detect the impairments in new acquired cognitive disorders that are not adequately captured by legacy tests.…”
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