Probabilistic nested model selection in pharmacokinetic analysis of DCE-MRI data in animal model of cerebral tumor by Hassan Bagher-Ebadian, Stephen L. Brown, Mohammad M. Ghassemi, Prabhu C. Acharya, Indrin J. Chetty, Benjamin Movsas, James R. Ewing, Kundan Thind

“…This nested model selection (NMS) assumes that the observed time-trace of contrast-agent (CA) concentration within a voxel, corresponds to a singular physiologically nested model. …”
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Body mass index impacts the lipid-lowing effects of statins in patients with type 2 diabetes by Lulu Sun, Zhuo Wang, Bai Wang, Yuxiang Jia, Qidi Zhao, Jingjun Zhao, Xingtao Huang

“…Over the 1-year follow-up period, lipid levels decreased in all patients, with a significant reduction observed in LDL-C levels. Notably, obese patients experienced the highest reduction in LDL-C levels compared to the normal and overweight groups (normal weight group ΔLDL 0.78 ± 0.95 mmol/L, p < 0.001; overweight group ΔLDL 0.80 ± 0.88 mmol/L, p < 0.001; obese group ΔLDL 1.11 ± 0.82 mmol/L, p < 0.038). …”
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The effects of magnitude of calcium decline at the onset of lactation on serotonin dynamics and the serotonin-calcium axis by M.K. Connelly, R.M. Rodney, J. Kuehnl, J.P.N. Andrade, F. Sonnewend Andrade, S. Henschel, E. Block, I.J. Lean, L.L. Hernandez

“…Time series analyses demonstrated that the pooled mean effect size (ES) of the relationship between ionized Ca and serotonin 36 h before parturition was significantly positive (ES = 0.164) prepartum. We also observed that the overall pooled mean ES of the relationship between prepartum blood pH 24 h prior and serotonin was significantly positive (ES = 0.111); however, for individual treatment groups, relationships were identified between blood pH and serotonin 18 and 6 h before only for the NDex group. …”
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Assessment of the genetic diversity of the alleles of gliadin-coding loci in common wheat (<i>Triticum aestivum</i> L.) collections in Kazakhstan and Russia by M. U. Utebayev, S. M. Dashkevich, O. O. Kradetskaya, I. V. Chilimova, N. A. Bome

“…The highest intravarietal polymorphism (51.1 %) was observed in wheat cultivars bred in Omsk region (Russia) and the lowest (16.6 %), in Pavlodar region (Kazakhstan). …”
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Assessment of in vitro skin permeation and accumulation of phenolic acids from honey and honey-based pharmaceutical formulations by Anna Nowak, Anna Muzykiewicz-Szymańska, Magdalena Perużyńska, Edyta Kucharska, Łukasz Kucharski, Karolina Jakubczyk, Paulina Niedźwiedzka-Rystwej, Justyna Stefanowicz-Hajduk, Marek Droździk, Juraj Majtan

“…Among the tested formulations - pure honey, hydrogel, and emulsion - higher skin permeation and accumulation rates of phenolic acids were observed with the prepared honey-based hydrogels than with the pure honeys and emulsions. …”
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PET Study of Sphingosine-1-phosphate Receptor 1 Expression in Response to S. aureus Infection by Hao Jiang, Jiwei Gu, Haiyang Zhao, Sumit Joshi, Joel S. Perlmutter, Robert J. Gropler, Robyn S. Klein, Tammie L. S. Benzinger, Zhude Tu

“…Particularly, compared to control mice, a 39% increase of [18F]TZ4877 uptake was observed in the infected muscle of S. aureus mice, indicating that S1PR1 expression was directly involved in the inflammatory response to infection. …”
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Comprehensive pan-cancer analysis reveals NTN1 as an immune infiltrate risk factor and its potential prognostic value in SKCM by Fuxiang Luan, Yuying Cui, Ruizhe Huang, Zhuojie Yang, Shishi Qiao

“…Additionally, a positive correlation was observed between NTN1 CNAs and its expression levels. …”
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Pharmacokinetics of Hydrogen During Hydrogen-Saturated Saline Infusion in Pigs by Masaki Shibuya, Masafumi Fujinaka, Mako Yonezawa, Natsumi Nishimura, Hitoshi Uchinoumi, Hiroshi Sunahara, Kenji Tani, Eiji Kobayashi, Motoaki Sano

“…No change in the PH or composition of the solution was observed due to hydrogen filling. The hydrogen concentrations of blood samples collected from the left internal jugular vein 3 cm to the heart from the tip of the infusion line were 6.4 (30 min), 4.7 (60 min), 4.9 (90 min), and 5.3 (120 min) ppb <i>w</i>/<i>w</i>, respectively. …”
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Biological sex, microglial signaling pathways, and radiation exposure shape cortical proteomic profiles and behavior in mice by Alexandra O. Strohm, Sadie Oldfield, Eric Hernady, Carl J. Johnston, Brian Marples, M. Kerry O'Banion, Ania K. Majewska

“…Surprisingly, radiation exposure caused relatively smaller proteomic changes in glial and synaptic proteins, including Rgs10, Crybb1, C1qa, and Hexb. While we observed some radiation effects on locomotor behavior, biological sex as well as loss of P2Y12 and CX3CR1 signaling had a stronger influence on locomotor outcomes in our model. …”
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Evaluation of Retinal Nerve Fiber Layer Thickness, Electroretinogram and Visual Evoked Potential in Patients with Alzheimer’s Disease by Qi Zhe Ngoo, Wan Hazabbah Wan Hitam, Asrenee Ab Razak

“…No significant difference and correlation were observed on PVEP readings. Conclusion. The mean of the average, superior and inferior RNFL thickness were significantly lower in the AD group compared with control. …”
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The Legionella pneumophila effector PieF modulates mRNA stability through association with eukaryotic CCR4−NOT by Harley O'Connor Mount, Malene L. Urbanus, Francesco Zangari, Anne-Claude Gingras, Alexander W. Ensminger

“…Adding to the complexities of PieF activity in vivo, we identified a separate domain of PieF responsible for binding to eukaryotic kinases. Unlike what we observe for CNOT6/6L, we show that these interactions can occur concomitantly with PieF’s binding to CNOT7. …”
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Multimodal Pain Recognition in Postoperative Patients: Machine Learning Approach by Ajan Subramanian, Rui Cao, Emad Kasaeyan Naeini, Seyed Amir Hossein Aqajari, Thomas D Hughes, Michael-David Calderon, Kai Zheng, Nikil Dutt, Pasi Liljeberg, Sanna Salanterä, Ariana M Nelson, Amir M Rahmani

“…Current methods of pain assessment often rely on subjective patient reports or behavioral pain observation tools, which can lead to inconsistencies in pain management. …”
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英國、臺灣、馬來西亞戶外冒險教育發展之 比較分析 A Comparative Analysis on Outdoor Adventure Education Development in England, Taiwan, and Malaysia by 李晟瑋 Cheng-Wei Li, 葉優寧 Evelyn Yeap Ewe Lin

“…A notable disconnection between schools and universities regarding OAE initiatives was observed in Malaysia. Additionally, the study highlighted the significance of considering cultural, societal, and policy contexts in shaping the landscape of OAE in diverse educational systems. …”
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Prospects for the use of a <i>Bacillus subtilis</i> metabolites-based feed additive in dairy farming by S. V. Malkov, A. S. Krasnoperov, A. P. Poryvaeva, O. Yu. Oparina, A. I. Belousov, A. N. Brilliant

“…Trend for increase in total protein concentration in cow sera owing to increase in albumin fraction was observed in postpartum period: it was 72.91 ± 3.45 g/l in test group 1; 75.54 ± 4.12 g/l in test group 2; 70.95 ± 4.25 g/l in control group. …”
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A study on microbiological and chemical changes during the production and storage of potassium sorbate treated and salted carp fillets by Bahri Patır, Ayşe Gürel, Gülsüm Ateş, Ahmet H. Dinçoğlu

“…During the preparation and siorage of ihe produci, the samples treated v/nh 10 % sailed and potassium sorbate were observed lo contain relatively less microorganisms [P > 0.05). …”
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A novel TID + IDN controller tuned with coatis optimization algorithm under deregulated hybrid power system by Geetanjali Dei, Deepak Kumar Gupta, Binod Kumar Sahu, Mohit Bajaj, Vojtech Blazek, Lukas Prokop

“…This assessment is based on the observation of dynamic responses across different controller configurations. …”
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Ethnobotanical studies on rice landraces under on-farm conservation in Xishuangbanna of Yunnan Province, China by Fei Wang, Tao Sun, Shuai Yu, Chunhui Liu, Zhuo Cheng, Jianxin Xia, Longzhi Han

“…Results A total of 70 rice landraces were collected in the Xishuangbanna region, each exhibiting distinct characteristics. Differences were observed across regions, trait, naming, and ethnic groups. …”
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A 32-year trend analysis of lower respiratory infections in children under 5: insights from the global burden of disease study 2021 by Yan Wang, Ruiyang Han, Xiao Ding, Junli Chen, Wenjia Feng, Chunping Wang, Runguo Gao, Anning Ma, Anning Ma

“…The disease burden was notably higher in children under 1 year old compared to those aged 2–4 years and the overall under-5 age group, with significant gender differences observed. Additionally, there was a strong negative correlation between the burden of lower respiratory infections in children under 5 and the socio-demographic index. …”
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Aux origines gauloises de Tours (Indre-et-Loire) : état des connaissances by Sandrine Linger-Riquier

“…The material culture includes ceramics, fibulae, Roman amphorae, and coins. The objects were observed in situ or in a secondary position and were spread over approximately 500 m from north to south (spanning the Place de la Victoire to the Clocheville Hospital), and approximately 500 m from east to west (from the Place de la Résistance to the Place des Halles), i.e. over a maximum area of approximately 25 ha. …”
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EFEKTIVITAS PEMANFAATAN ALUN-ALUN SEBAGAI RUANG TERBUKA PUBLIK by Muhammad Uliah Shafar, Suzanna Ratih Sari

“…Through the sketches and symbols from the observations made in the morning and evening using the place center map method, user behavior was known to the facilities used in the Andi Makkasau square. …”
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