First-in-human phase 1 study of the arginase inhibitor INCB001158 alone or combined with pembrolizumab in patients with advanced or metastatic solid tumours by Michael Smith, Aung Naing, Todd Bauer, Kyriakos P Papadopoulos, Osama Rahma, Elena Garralda, Glenn J Hanna, Michael J Pishvaian, Xuejun Chen, Sven Gogov, Omar Saavedra, Howard Kallender, LuLu Cheng, Emil Kuriakose

“…Overall, the limited antitumour activity of arginase inhibition observed suggests that the role of arginine depletion in cancer is multifaceted.Trial registration number NCT02903914.…”
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Primary repair vs arthroscopic reconstruction for proximal anterior cruciate ligament tears: a comparative study by Sergey A. Gerasimov, Ekaterina A. Morozova, Daria A. Naida, Denis O. Kolmakov, Andrey A. Zykin, Ekaterina V. Khramtsova

“…Chondrolabral defects were observed in 15.5±0.04% of patients with primary repair, and in 10.5±0.03% of patients from the reconstruction group. …”
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IDENTIFIKASI PEMBEKALAN KETERAMPILAN ABAD 21 PADA ASPEK LITERASI TEKNOLOGI INFORMASI DAN KOMUNIKASI SISWA SMA NEGERI BENGKULU DALAM MATA PELAJARAN FISIKA by Annisatul Jannah, Afrizal Mayub, Dedy Hamdani

“…Data collection techniques used in this study are questionnaires, interviews and observations. Based on data analysis, it was obtained and mastery by providing of 21st century skills in the aspects of information and communication technology literacy for Bengkulu city high school students in physics according to teacher perceptions, themselves and their peers were in a good category. …”
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Metrics for Evaluating Telemedicine in Randomized Controlled Trials: Scoping Review by Yuka Sugawara, Yosuke Hirakawa, Masao Iwagami, Ryota Inokuchi, Rie Wakimizu, Masaomi Nangaku

“…ConclusionsA significant variation was observed in the metrics used across previous studies. …”
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Comparative analysis of the primary structure and production of recombinant poly(ADP-ribose)polymerase 1 of long-lived Heterocephalus glaber by K. N. Naumenko, A. R. Nurislamov, K. D. Nazarov, V. S. Fishman, A. A. Popov, I. O. Petruseva, A. N. Evdokimov, O. I. Lavrik

“…High activity of DNA repair systems is observed in the cells of the naked mole rat, which ensures their high resistance to oxidative stress, as well as to genotoxic effects. …”
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A Physics-Based Hyper Parameter Optimized Federated Multi-Layered Deep Learning Model for Intrusion Detection in IoT Networks by Chirag Jitendra Chandnani, Vedik Agarwal, Shlok Chetan Kulkarni, Aditya Aren, D. Geraldine Bessie Amali, Kathiravan Srinivasan

“…The study provides a comprehensive comparison with the most recent physics based HPO techniques. This study observes that coupling a Deep-Learning model with HPO techniques results in a much faster convergence requiring only 10-15 communication rounds. …”
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Hubungan Antara Lamanya Ketuban Pecah Dini dengan Keberhasilan Induksi Persalinan pada Pasien Aterm di RSUP Dr. M. Djamil Padang by Juan Habli Soufal, Ariadi ., Sofina Rusdan Rusdan

“…Djamil Padang.This study used a retrospective observational analytic methods with cross sectional design. …”
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A murine model of Trypanosoma brucei-induced myocarditis and cardiac dysfunction by Nathan P. Crilly, Marcelle Dina Zita, Alexander K. Beaver, Polina Sysa-Shah, Aashik Bhalodia, Kathy Gabrielson, Luigi Adamo, Monica R. Mugnier

“…Cardiac symptoms are commonly reported in HAT patients, and intracardiac parasites with accompanying myocarditis have been observed in both natural hosts and animal models of T. brucei infection. …”
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Cost-utility and cost–benefit analysis of a multi-component intervention (NEXpro) for neck-related symptoms in Swiss office workers by Beatrice Brunner, Andrea Martina Aegerter, Venerina Johnston, Thomas Volken, Manja Deforth, Gisela Sjøgaard, Achim Elfering, Markus Melloh, the NEXpro Collaboration Group

“…The main analysis included 392 observations. The intervention had a significant positive effect on QALYs and a nonsignificant effect on costs. …”
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Mollusk Diversity in Percut Sei Tuan Silvofishery Ponds, North Sumatra, Indonesia by Ipanna Enggar Susetya, Mohammad Basyuni, Muhammad Rakezza Rifzy Rifzy, Rizka Amelia, Yuntha Bimantara, Rusdi Leidonald, Amanatul Fadhilah

“…A total of 16 species of mollusks were found at the observation site, consisting of gastropods and bivalves. …”
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Modelación y análisis de susceptibilidad a la deformación permanente de mezclas asfálticas Modeling and analysis of susceptibility to permanent deformation in asphalt mixtures by Julián Vidal V, Alexander Ossa

“…By means of an experimental study on mixtures, it was found that their behavior under steady state condition followed the model modified by Cross², thus mixtures showed a visco-linear and non-linear behavior at low and high stress levels, respectively. It was observed that under loading and unloading conditions, there is a temperature dependence on the material behavior, which was properly predicted by Arrhenius3 under the studied temperatures interval. …”
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PENTAHELIX ANALYSIS DALAM UPAYA MITIGASI BENCANA DI DESA SELOK ANYAR KECAMATAN PASIRIAN KABUPATEN LUMAJANG by Achmad Fathoni, Kalvin Edo Wahyudi

“…Research Methods used in this study used qualitative methods with descriptive purposes with data collection techniques using interviews, observations, and documentation. The results of this study show that disaster mitigation efforts carried out by the pentahelix component in Selok Anyar Village, Pasirian District, Lumajang Regency, East Java, have been running. …”
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Beneficiaries’ satisfaction with health insurance and associated factors in Sub-Saharan Africa: a systematic review and meta-analysis by Abubeker Alebachew Seid, Bizunesh Fantahun Kase, Abdu Hailu Shibeshi, Molla Getie Mehari, Abdulkerim Hassen Moloro

“…This systematic review and meta-analysis aimed to assess the proportion of beneficiaries satisfied with health insurance and identify factors associated with their satisfaction in Sub-Saharan Africa (SSA).Design A systematic review and meta-analysis were conducted in accordance with the Preferred Reporting Items for Systematic Review and Meta-analysis guidelines.Data sources PubMed/MEDLINE, African Journals Online, Cumulative Index to Nursing & Allied Health Literature and Google Scholar were searched up to 23 May 2024.Eligibility criteria Observational and quantitative studies conducted in SSA that reported the proportion of health insurance beneficiaries satisfied with the scheme and/or determined factors associated with satisfaction were included.Data extraction and synthesis Data were extracted using Microsoft Excel and analysed with STATA V.17 software. …”
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Baicalin Mitigates Cardiac Hypertrophy and Fibrosis by Inhibiting the p85a Subunit of PI3K by Lu He, Min Zhu, Rui Yin, Liangli Dai, Juan Chen, Jie Zhou

“…Molecular docking was carried out to reveal the effect of baicalin on p85a. <b>Results:</b> We observed significant antihypertrophic and antifibrotic effects of baicalin both in vivo and in vitro. …”
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A Comparison of Medial-congruent, Ultracongruent, and Cruciate-retaining Bearings Using a Single Cruciate-retaining Total Knee Design by Alexander V. Strait, MS, Eric J. Wilson, MD, Henry Ho, MS, Kevin B. Fricka, MD, Robert A. Sershon, MD

“…Conclusions: No differences in all-cause complications or revisions were observed for MC, UC, and CR bearings using the same total knee system. …”
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Mechanism of Mongolian Medicine Batri-7 on Salmonella Enteritis by Yang D, Chen S, Borijihan H, Aoqier A, Sarula S, Siqin S, Manda M, Temuqile T, Baigude H

“…Of them, we found multiple antibacterial and anti inflammation compounds including chrysin, oroxylin A and luteolin. In vivo, we observed that treatment of mouse Salmonella enteritis with BT-7 decreases inflammation score and macrophages on intestinal tenue. …”
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Disrupting of IGF2BP3-stabilized CLDN11 mRNA by TNF-α increases intestinal permeability in obesity-related severe acute pancreatitis by Lihui Lin, Yansong Lin, Xianwen Guo, Ruoyi Zhang, Xin Ling, Zewen Zhang, Rong Lin, Zhen Ding

“…Results Downregulation of CLDN11 was observed in the intestinal epithelial cells of experimental obesity-related SAP. …”
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Identifikasi Bakteri Coliform pada Air Kobokan di Rumah Makan Kelurahan Andalas Kecamatan Padang Timur by Ervan Arditya Kusuma, Roslaili Rasyid, Endrinaldi

“…This research implemented in two steps: taking the water for cleaning hand sample and also observing factor affecting contamination of the water for cleaning hand, then bacteriologi inspection using Most Propable Number (MPN) methods to presumptive test, confirmation test and complementary test. …”
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Budget Impact of Rivaroxaban for the Prevention of Thromboembolic Events after Hip or Knee Replacement in Spain by Xavier Granero Xiberta, Antonio Murcia, José Ricardo Troncoso Durán, Claudio Gómez Zubeldia, Aleix Llorac Moix, Ruth Graefenhain De Codes, Maria Giovana Ferrario, Luis Lizán

“…Data related to rate of thromboembolic events, major bleeding events and use of resources (local or general anesthesia and nurse care after surgery) were obtained from the Xarelto® for VTE Prophylaxis After Hip or Knee Arthroplasty (XAMOS) study, an international, non-interventional, observational, open-label study in unselected patients undergoing THR or TKR surgery in routine practice. …”
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Estimation of Apolipoprotein A1, Haptoglobin and Alpha 2macroglobulin with some Biochemical Metabolic Markers in Nonalcoholic Fatty Liver Disease Iraqi Patients by hiba abid Al-hussein hassan, Dawood Salman Dawood, Raghad Jawad Hussein

“…Furthermore, the present study observed that the optimal cut-off value was ≤67.13ng/ml for haptoglobin with a sensitivity and specificity of 80% and 93.33% respectively. …”
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