The management and clinical outcome of paracetamol poisoning in South African adults: A single-centre retrospective review by C Kotze, J Swanepoel, E C Kruger, E Decloedt

“…A high case fatality rate was observed in the studied population. Early identification of at-risk individuals and prompt initiation of NAC can reduce poor outcomes. …”
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Knowledge, attitude and practice regarding screening and managing diabetic microvascular complications among general practitioners of community health centres: a cross-sectional st... by Hua Yang, Jian Gao, Ying Yu, Cuiling Huang, Chengdian Lan, Zhangyan Chen

“…The KAP total score increased with the working years of general practice; however, this effect was no longer observed in knowledge score after 15 years, while the attitude and practice scores showed a continuously increasing trend.Conclusions GPs showed insufficient knowledge and poor clinical practice on screening and managing diabetic microvascular complications. …”
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Taenia solium taeniosis and cysticercosis literature in Tanzania provides research evidence justification for control: A systematic scoping review. by Helena Aminiel Ngowi, Andrea Sylvia Winkler, Uffe Christian Braae, Robinson Hammerthon Mdegela, Ernatus Martin Mkupasi, Mwemezi Lutakyawa Kabululu, Faustin Peter Lekule, Maria Vang Johansen

“…<h4>Conclusions/significance</h4>The observed high burden of TSTC and the significant contribution of NCC to epilepsy in Tanzania warrant urgent interventions. …”
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Prevalence of Vitamin K2 Deficiency and Its Association with Coronary Artery Disease: A Case–Control Study by Sameh A. Ahmed, Abdulaziz A. Yar, Anas M. Ghaith, Rayan N. Alahmadi, Faisal A. Almaleki, Hassan S. Alahmadi, Waleed H. Almaramhy, Ahmed M. Alsaedi, Man K. Alraddadi, Hussein M. Ismail

“…The most pronounced decrease in MK-4 and MK-7 was observed in unstable angina patients. Moreover, these outcomes indicate the imperative requirement for an integrative approach that incorporates metabolic, lipid, and vitamin K2-related pathways in the risk stratification and management of CAD.…”
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Forecasting stroke and stroke-driven dementia in a rapidly ageing population: a model-based analysis of alternative projection scenarios for Ireland by Anne Hickey, Eithne Sexton, Frances Horgan, Kathleen E Bennett, Ronan Collins, Martin O'Flaherty, Suzanne Timmons, Chris Macey, David J. Williams

“…We used multiple data sources, including systematic review and observational evidence.Interventions Not applicable.Primary and secondary outcome measures We projected the incidence and prevalence of stroke (International Classification of Disease (ICD) codes I60–I61, I63–I64), poststroke dementia (Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-V) criteria) and poststroke disability (modified Rankin Scale 3–5).Results The stable scenario indicated a projected 85 834 stroke survivors in 2046 (95% uncertainty interval (UI)=82 366–89 655), an increase of 45.7% from 2022. …”
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Associations among circulating sphingolipids, β-cell function, and risk of developing type 2 diabetes: A population-based cohort study in China. by Huan Yun, Liang Sun, Qingqing Wu, Geng Zong, Qibin Qi, Huaixing Li, He Zheng, Rong Zeng, Liming Liang, Xu Lin

“…<h4>Conclusions</h4>In this study, we observed that a panel of novel sphingolipids with unique structures were positively associated with incident T2D, largely mediated through β-cell dysfunction, in Chinese individuals.…”
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The use of bacterial culture for Leptospirosis di- agnosis in female water buffaloes by Rosaura Pérez-Gil, Oriana Gavidia, Juan Torres

“…Histopathology analysis showed lesions in the spleen as extra-medullary hematopoiesis and hemorrhage; in the kidney (multifocal hemorrhages, tubular degeneration, and edema) while in the lungs, perivascular hemorrhages and degeneration of the vascular wall were observed. In conclusion, these preliminary results suggest that the MAT cannot diagnose all Leptospirosis cases correctly, especially chronic infections characterized by low antibodies. …”
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Human Factors Studies to Assess the Usability of the Faricimab Prefilled Syringe by Barakat MR, Kwong Jr HM, Marcon G, O'Leary OE, Paris LP, Schneider P, Tang Y, Graff JM

“…Of the 22 tasks, the pass rate was 86.7– 100%; 16 tasks had a pass rate of 100%. No use errors were observed during the actual-use study. One patient experienced one mild adverse event of eye irritation that resolved the same day and was deemed unrelated to the study drug.Conclusion: Participants were able to safely and correctly prepare and administer a faricimab 6 mg dose using the PFS in accordance with the instructions for use, under realistic conditions representing the real world. …”
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Hubungan Pemakaian Fenobarbital Rutin dan Tidak Rutin Pada Anak Kejang Demam dengan Attention Deficit Hyperactivity Disorder (ADHD) by Sara Fadila, Nadjmir ., Rahmatini .

“…This research using observational analytic cross sectional design performed on 32 samples, consisting of 16 patients with febrile seizures regularly taking phenobarbital daily and 16 patients with febrile seizures do not routinely taking phenobarbital. …”
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Effects of tongue tamers and customized bonded spurs as an early treatment of anterior open bite: a randomized clinical study by Safa B. Alawy, Shaimaa S. EL-Desouky, Ibrahim A. Kabbash, Shimaa M. Hadwa

“…Overjet decreased in all groups, with the greatest reduction observed in group-I(-2.58 ± 1.02 and -2.47 ± 0.80 in model and cephalometric respectively) and was significantly different from group-II using pairwise analysis. …”
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Comparative Analysis of Meat Quality and Hindgut Microbiota of Cultured and Wild Bighead Carp (<i>Hypophthalmichthys nobilis</i>, Richardson 1845) from the Yangtze River Area by Abdullateef Mukhtar Muhammad, Chang Yang, Bo Liu, Cunxin Sun, Linghong Miao, Xiaochuan Zheng, Liangkun Pan, Dong Xia, Qun-Lan Zhou

“…Consequently, differences in meat quality, particularly in the fatty acid composition, were observed between wild and cultured bighead carp. These differences may be associated with variations in the hindgut microbiota, shedding light on the gut–muscle axis.…”
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Establishment and validation of predictive model of ARDS in critically ill patients by Senhao Wei, Hua Zhang, Hao Li, Chao Li, Ziyuan Shen, Yiyuan Yin, Zhukai Cong, Zhaojin Zeng, Qinggang Ge, Dongfeng Li, Xi Zhu

“…However, ARDS is frequently underdiagnosed or delayed, and its heterogeneity diminishes the clinical utility of ARDS biomarkers. This study aimed to observe the incidence of ARDS among high-risk patients and develop and validate an ARDS prediction model using machine learning (ML) techniques based on clinical parameters. …”
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OCT Biometry (B-OCT): A New Method for Measuring Ocular Axial Dimensions by Bartosz L. Sikorski, Pawel Suchon

“…To present a new method of measuring ocular axial dimensions, termed OCT biometry (B-OCT). Design. Observational cross-sectional study and evaluation of new diagnostic technology. …”
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Molecular Characterization, Oxidative Stress-Mediated Genotoxicity, and Hemato-Biochemical Changes in Domestic Water Buffaloes Naturally Infected with <i>Trypanosoma evansi</i> Und... by Waqas Ahmad, Muhammad Yasin Tipu, Muti ur Rehman Khan, Haroon Akbar, Aftab Ahmad Anjum, Muhammad Ovais Omer

“…The mean trypomastigote count observed in the infected buffaloes was 5.15 × 10⁶ (±5.3 × 10²)/µL of blood. …”
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Exploratory study on the ascending pain pathway in patients with chronic neck and shoulder pain based on combined brain and spinal cord diffusion tensor imaging by Zhiqiang Qiu, Tianci Liu, Chengxi Zeng, Maojiang Yang, HongYing Yang, Xiaoxue Xu

“…Conversely, significant abnormalities were observed in specific segments of the bilateral cervical STT (p &lt; 0.05), which were also correlated with variations in pain intensity, illness duration, and levels of anxiety and depression. …”
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Analisis Sistim Manajemen Dokumentasi Keperawatan pada Poliklinik Gigi Rumah Sakit di Bukittinggi by Dewi Rosmalia, Rizanda Machmud, Haryadi Mangkuto

“…The study was conducted with qualitative analysis methods, data sources derived from observations, documents and in-depth interviews. Informants numbered 10 ( ten ) members consisting of the hospital director, chief dental nurses union Indonesia ( PPGI ) of Bukittinggi, the head of the room / installation and head nurse at the dental clinic dental hospital in Bukittinggi. …”
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Good soil management can reduce dietary zinc deficiency in Zimbabwe by Muneta G. Manzeke-Kangara, Edward J. M. Joy, Florence Mtambanengwe, Prosper Chopera, Michael J. Watts, Martin R. Broadley, Paul Mapfumo

“…To estimate current Zn deficiency in Zimbabwe, data on dietary Zn supply from non-maize sources from the Global Expanded Nutrient Supply (GENuS) data set were linked to maize grain Zn composition observed under typical current soil fertility management scenarios. …”
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Influence of minor hydrocarbon seepage on sulfur cycling in marine subsurface sediments by E. Schnabel, A. Vuillemin, C. C. Laczny, B. J. Kunath, A. R. Soares, A. J. Probst, R. Di Primio, J. Kallmeyer

“…The analysis of 50 gravity cores revealed significant variability in the predicted sulfate depletion depth, ranging from 3 to 12 m below the seafloor. We observed nearly linear pore water sulfate and alkalinity profiles, alongside low rates of sulfate reduction (pmol cm<span class="inline-formula">³</span> d<span class="inline-formula">⁻¹</span>). …”
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Characteristics of the First Italian Older Adults Vaccinated with an Adjuvanted Respiratory Syncytial Virus (RSV) Vaccine by Alexander Domnich, Andrea Orsi, Piero Luigi Lai, Elvira Massaro, Carlo-Simone Trombetta, Julieta Pastorino, Charlott Roihl, Marianna Pianta, Giancarlo Icardi, Donatella Panatto

“…More positive attitudes towards RSV vaccination were observed (<i>p</i> < 0.01) among subjects who received more COVID-19 vaccine doses, whose reasons for the current RSV vaccination were the willingness to be protected or to be in good health and the feeling of being at risk for RSV. …”
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Enrichment of electrotrophic microorganisms from contrasting shallow-sea hydrothermal environments in bioelectrochemical reactors by Antoine Carissimo, Victoria Comes, Alenica Heussner, Anne-Hélène Prime, Roy E. Price, Gaël Erauso, Pierre-Pol Liebgott, Sven Kerzenmacher, Guillaume Pillot

“…By contrast, a 6-fold increase on average was observed in reactors operated under the Panarea hydrothermal fluid conditions (pH 4.5–7, 75°C). …”
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