Bubbling insights: unveiling the true sophorolipid biosynthetic pathway by Starmerella bombicola by Sophie L. K. W. Roelants, Stijn Bovijn, Elvira Bytyqi, Nicolas de Fooz, Goedele Luyten, Martijn Castelein, Thibo Van de Craen, Zhoujian Diao, Karolien Maes, Tom Delmulle, Maarten De Mol, Sofie L. De Maeseneire, Bart Devreese, Wim K. Soetaert

“…However, new experiments performed with respective S. bombicola strains Δsble, Δat Δsble, and ∆at revealed inconsistencies with the current understanding of the SL pathway. It was observed that the ∆sble strain produces mainly bolaform sophorolipids with higher acetylation degrees instead of acidic sophorolipids. …”
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Pediatric bacterial meningitis in southern China: analysis of 838 cases by Lianfeng Chen, Wen-Lin Wu, Yuanyuan Gao, Xiaojing Li, Sida Yang, Huici Liang, Kelu Zheng, Yani Zhang, Haixia Zhu, Yang Tian, Bingwei Peng, Haisheng Lin, Xiuying Wang, Shuyao Ning, Yinyan Gan, Chi Hou, Yinting Liao, Huiling Sheng, Wen-Xiong Chen, Wen-Xiong Chen

“…Differences in symptoms, pathogens, CSF results, brain MRI, and GOS points were observed across age groups (neonate [29 days, 12 months) and aged ≥12 months). …”
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Booster Vaccination against Yellow Fever in Gambian children-(BoVY) -a Phase 3 clinical trial to establish safety and immunogenicity of repeated YF vaccination in healthy Gambian c... by David Jeffries, Caitlin Pley, Beate Kampmann, Mam Nabou Leigh, Julia Strandmark, Ed Clarke, Peter Ndow, Ebrima Kanteh, Amadou Faal, Elishia Roberts

“…A highly effective vaccine against YF is licensed and recommended as part of routine childhood immunisation as a single dose at 9 months. Recent observational data demonstrate waning immunity following single primary vaccination and suggest that children in endemic areas may require booster vaccination. …”
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Promotion of microfracture-mediated cartilage repair by the intra-articular injection of Mg2+ by Zhian Chen, Tianhua Zhou, Zhengbo Yin, Peiya Duan, Ying Zhang, Yujiao Feng, Rongmao Shi, Yongqing Xu, Rongqing Pang, Hongbo Tan

“…Cartilage damage was detected by gross observation, micro-CT, and histological analysis. The expression levels of related genes were detected by real-time quantitative reverse transcription polymerase chain reaction (RT-qPCR). …”
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Disease-Related Knowledge, Stress, and Quality of Life of Parental Caregivers of Children with Cleft Lip and Palate in a Selected Hospital in Ho Chi Minh City, Vietnam by Phung Le Thi Kim, Leonora Collantes, Phuong Lam Hoai, An Phan Huynh, Nghia Le Trung, Tu Nguyen Thanh, Anh Nguyen Viet, Kieu Nguyen Thi Thanh, Truc Pham Thanh Luu, Phi Duong Nguyen

“…A significant positive correlation was found between knowledge and stress (r=0.421, p<0.001), but no significant correlation was observed between knowledge and QoL (r=-0.033, p=0.619). …”
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Predictive effect of estimated glomerular filtrate rate by creatinine or cystatin C on mortality in patients with coronary artery disease by Shiqun Chen, Yang Zhou, Guoxiao Liang, Wanying Wu, Zhigang Huang, Lile Shi, Yuwei Gao, Xia Gu, Dongmei Wang

“…Similar results were observed in all-cause mortality. Restricted cubic spline showed a U-shaped association between eGFRcr and all outcomes in patients with both reduced and supranormal eGFR levels, while a L-shaped association in eGFRcys and eGFRcr-cys.Conclusions Estimated GFR based on both creatinine and cystatin C has highest predictive effect for cardiovascular and all-cause mortality among CAD patients. …”
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Application of Minocycline-Containing Bismuth Quadruple Therapies as First-Line Regimens in the Treatment of Helicobacter pylori by Lingyun Zhang, Yu Lan, Qi Wang, Yuexia Zhang, Xiaobei Si

“…No significant differences were observed at baseline data among the three groups (p>0.05). …”
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Oxamflatin and ascorbic acid improves developmental competence and quality of buffalo (Bubalis bubalis) cloned embryos by Sonal Gupta, Gaurav Tripathi, Kartikey Patel, Ram Parsad, Tanya Gupta, Naresh L. Selokar, Manoj Kumar Singh

“…The cloned embryos were transferred to the synchronized recipient (n=15 to18 buffaloes in each group), and the conception rate was observed better in combined treatment (OxF+AA) (46.66%) than oxamflatin (16.66%) and ascorbic acid (12.50%). …”
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Faktor-Faktor yang Berhubungan dengan Perilaku Seksual Remaja di Kota Padang by Mahmudah ., Yaslinda Yaunin, Yuniar Lestari

“…The objective of this study was to observe the factors that can be related to adolescent sexual behavior in Padang. …”
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Research on the multi-agent motivation coupling evolution and synergy improvement for farmland ecological protection in China by Adila Ainiwaerjiang, Xueying Jin, Zhen Xie, Tian Tian, Yuxuan Dang

“…Specifically, areas where synergistic efforts between implementers and producers in farmland ecological protection are being observed have expanded, while areas exhibiting decaying synergy have contracted. …”
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Low Incidence of Postoperative Respiratory Depression with Oliceridine Compared to Morphine: A Retrospective Chart Analysis by Sergio Bergese, Richard Berkowitz, Paul Rider, Martin Ladouceur, Suzanne Griffith, Alvaro Segura Vasi, Kristina Cochrane, Linda Wase, Mark A. Demitrack, Ashraf S. Habib

“…This retrospective, observational chart review study compared respiratory depression events associated with oliceridine administration as found in the ATHENA trial to a control cohort treated with conventional opioids. …”
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Postpartum depression in relation to chronic diseases and multimorbidity in women’s mid-late life: a prospective cohort study of UK Biobank by Yue Zhang, Yangyang Cheng, Rodrigo M. Carrillo-Larco, Yaguan Zhou, Hui Wang, Xiaolin Xu

“…Chronic diseases also accumulated at a faster annual rate for women with a history of PPD (b = 0.009, 95% CI = 0.007–0.011), compared to those without. We observed no interaction or mediation effects of physical activity, smoking, alcohol drinking, and dietary factors on the association between PPD and multimorbidity; however, women’s body mass index at baseline contributed to the association, with the mediation proportion of 6.38% (2.56–10.20%). …”
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L’amphithéâtre de Reims/Durocortorum : nouveaux éléments de localisation et de datation by Pierre Mathelart

“…When examined together, they define and delineate the scope of the overview IV, in terms of the evolution of ancient tableware in Reims. Careful observation of the different proportions of the categories and types of ceramics in the corpus, as well as in other contemporary Reims reference contexts now allows us to subdivide this scope in two. …”
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Inferior vena cava diameter in patients with chronic heart failure and chronic kidney disease: a retrospective study by Jianan Li, Chi Wang, Hui wu Dong, Jing Qi, Chongyou Rao, Qiuyang Li, Kunlun He

“…Results During a median follow-up of 3.46 years (IQR: 1.55–5.15 years), 757 (57.05%) cases of all-cause mortality were observed. Compared with patients with IVC diameter < 21 mm, those with IVC diameter > 21 mm were associated with higher risk of all-cause mortality (HR (95%CI):1.31(1.07–1.61), log rank: P = 0.01) and cardiovascular mortality (HR (95%CI): 1.55(1.19–2.04), log rank: P = 0.001). …”
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Atrial fibrillation in acute coronary syndrome: clinical and anamnestic features and effects on the course by V.І. Tseluyko, F.B. Salem, N.A. Lopina, I.V. Kuznetsov

“…A retrospective and prospective study was conducted among 206 patients with ACS (mean age 65.00 ± 10.75 years, 63.0 % of men) hospitalized with ACS at the center of percutaneous coronary interventions during period from 2015–2018. 125 patients with ACS were included into further observation. Depending on the presence of AF, patients with ACS were divided into 2 groups: group I (n = 65) – patients with ACS and AF, group II (n = 60) – patients with ACS without AF. …”
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Interactive effect of dietary metabolizable energy levels with amino acid density in male broiler chickens: Carcass yield, nutrient intake, digestibility and excretion by Mehdi Toghyani, Shemil MacElline, Peter H. Selle, Sonia Y. Liu

“…No interactions were observed between ME and AA densities on carcass characteristics, nutrient digestibility, and excretion (P > 0.05). …”
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Immune responses of cattle vaccinated by various routes with Mycobacterium bovis Bacillus Calmette-Guérin (BCG) by Mitchell V. Palmer, Soyoun Hwang, Carly Kanipe, Ellie J. Putz, Luis Guilherme Virgilio Fernandes, Anna Didkowska, Paola M. Boggiatto

“…Similar to oral lyophilized BCG vaccinated animals, we did not observe any significant increases in the frequency of CD8 and γδ T cell proliferative and IFN-γ responses following SQ or oral liquid vaccinated animals. …”
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Heart Rate in Hypertension: Review and Expert Opinion by Jamshed Dalal, Arup Dasbiswas, Immaneni Sathyamurthy, Srinivasa Rao Maddury, Prafulla Kerkar, Sandeep Bansal, Joy Thomas, Sankar Chandra Mandal, Soura Mookerjee, Sivakadaksham Natarajan, Viveka Kumar, Nishith Chandra, Aziz Khan, R. Vijayakumar, J. P. S. Sawhney

“…A linear association between the two is observed especially in individuals with HR >80 bpm. …”
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Evaluation of Health Science Students&rsquo; Knowledge, Attitudes, and Practices Toward Artificial Intelligence in Northern Saudi Arabia: Implications for Curriculum Refinement and... by ALruwail BF, Alshalan AM, Thirunavukkarasu A, Alibrahim A, Alenezi AM, Aldhuwayhi TZA

“…Additionally, multivariate analysis was employed to identify associated factors.Results: The present study demonstrated low knowledge, attitude, and practices among 55.7%, 37.0%, and 50.3% of health science students. We observed a positive correlation between knowledge and attitude (rho = 0.451, p = 0.001), knowledge and practice (rho = 0.353, p = 0.001), and attitude and practice (rho = 0.651, p = 0.001). …”
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Short-acting beta agonist, antibiotics, oral corticosteroid and association with mortality and cardiopulmonary events in patients with COPD: a retrospective cohort study in Alberta... by Mohit Bhutani, Irvin Mayers, Arsh Randhawa, Manisha Talukdar, Suzanne McMullen, Phongsack Manivong, Aaron Gelfand

“…Associations were modelled between mortality and SABA, antibiotic and OCS history, and between major adverse cardiac events (MACE) and cardiovascular disease (CVD) death and SABA history.Results Among 188 969 patients, dose–response effects were observed. Adjusting for covariates, rates were higher for patients with 6+ (vs 1) SABA dispenses (all-cause mortality HR: 1.20, 95% CI 1.16 to 1.24, p&lt;0.001; COPD-related mortality HR: 1.40, 95% CI 1.34 to 1.46, p&lt;0.001). …”
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