Genomic interrogation of invasive group A Streptococcus (iGAS) epidemiology and COVID-19 impacts in Victoria, Australia: a 6-year retrospective studyResearch in context by Jacqueline M. Morris, Jake A. Lacey, Kerrie Stevens, Lamali Sadeesh Kumar, Mathilda Wilmot, Janet Strachan, Marion Easton, Daneeta Hennessy, Tony M. Korman, Andrew J. Daley, Katherine B. Gibney, Adam W.J. Jenney, Steven Y.C. Tong, Benjamin P. Howden, Norelle L. Sherry

“…Low levels of antimicrobial resistance were observed, primarily to macrolides and tetracyclines. …”
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WT1 Peptide Cancer Vaccine for Patients with Hematopoietic Malignancies and Solid Cancers by Yoshihiro Oka, Akihiro Tsuboi, Olga A. Elisseeva, Hiroko Nakajima, Fumihiro Fujiki, Manabu Kawakami, Toshiaki Shirakata, Sumiyuki Nishida, Naoki Hosen, Yusuke Oji, Ichiro Kawase, Haruo Sugiyama

“…These results strongly suggested that the WT1 peptide cancer vaccine had efficacy in the clinical setting because clinical responses, including reduction of leukemic blast cells or regression of tumor masses, were observed after the WT1 vaccination in patients with hematopoietic malignancies or solid cancers. …”
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Decrease in phase angle after Roux-en-Y gastric bypass is related to increase of anti-inflammatory status by Amanda Cristina Araújo Gomes, Amanda Machado Fiorotti, Amanda Motta de Bortoli, Beatriz Bobbio de Brito, João Arthur Souza Fiorido, Luciane Bresciani Salaroli, Andressa Bolsoni Lopes, Fabiano Kenji Haraguchi

“…A significant decrease in PhA values accompanied by an improvement in inflammatory parameters were observed post-RYGB (p<0.05). PhA values was inversely correlated with serum adiponectin concentrations (r= −0.376, p<0.05). …”
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Prognostic Value of CXCL13, CCL11, and CCL20 Chemokines in Multiple Sclerosis by Işıl Peker, Hacer Eroğlu İçli, Belgin Mutluay, Burcu Yüksel, Zeynep Özdemir, Mesrure Köseoğlu, Aysu Şen, Dilek Ataklı, Aysun Soysal, Musa Öztürk

“…<b>Results:</b> No significant differences were observed among the groups in serum levels of CXCL13, CCL11, and CCL20 (<i>p</i> = 0.509, <i>p</i> = 0.979, <i>p</i> = 0.169, respectively). …”
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Neural Correlates of Social Perception Deficit in Schizophrenia: An Event-related Potential Study by Jiang-juan Li, Xin-ping Li, Jia-min Han, Yi-fan Sun, Xiao-hong Liu, Xue-zheng Gao, Li-min Chen, Zhen-he Zhou, Hong-liang Zhou

“…Conclusions: Schizophrenia patients present impaired social perception, and the observed ERP patterns provide valuable insights into the neural mechanisms underlying the EIRT results, highlighting the differences between HCs and schizophrenia patients. …”
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Preparation, Reliability, and Validity of a Japanese Version of the “Satisfaction of Treatment among Caregivers of Dependent Type 2 Diabetic Patients” Questionnaire by Satoshi Ida, Ryutaro Kaneko, Kanako Imataka, Kaoru Okubo, Yoshitaka Shirakura, Kentaro Azuma, Ryoko Fujiwara, Hiroka Takahashi, Kazuya Murata

“…Significant correlations were observed between the STCD2-J scores and degree of satisfaction with patients’ blood glucose levels (r=0.43, P<0.001), depression (r=−0.20, P=0.003), and negative self-assessment of nursing care (r=−0.19, P=0.004). …”
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Adipose tissue may not be a major player in the inflammatory pathogenesis of Autism Spectrum Disorder by Baojiang Wang, Yueyuan Qin, Yong Chen, Xiujie Zheng, Yanjuan Chen, Juan Zhao, Feng Zhang, Shan Duan

“…Similar results were also observed in BTBR autistic mice. Notably, levels of insulin, which are closely related to the exertion of adipokines function, also showed no significant changes. …”
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Cultivatable Bacteriota of Chronic Wound of Patients with Diabetic Foot Syndrome with Critical Limb Ischemia Based on Wound Biopsy in Peri-Revascularization Period by Syedah Sarah Hussaini, Fran Dominic Grubesa, Mateusz Gajda, Martyna Schönborn, Katarzyna Bogucka, Mikołaj Maga, Paweł Maga, Jadwiga Wójkowska-Mach

“…No cases of reocclusion or restenosis were observed during the study; however, small amputations were performed in two patients (8.7%). …”
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Scenario Simulation of Ecosystem Services Based on Land Use/Land Cover Change in the Bailong River Basin, in China by Shuangying Li, Yanyan Zhou, Dongxia Yue, Zhongling Guo, Zhi Li

“…Built-up land and farmland increased, and ESs decreased significantly under the SSP5-8.5 scenario. (2) Synergistic effects were identified among the ESs, with the most pronounced synergy observed between CS and HQ. Spatially, six pairs of ESs under the SSP1-2.6 scenario showed synergistic effects. …”
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Genetic Association and Expression Correlation between Colony-Stimulating Factor 1 Gene Encoding M-CSF and Adult-Onset Still’s Disease by Yi-Ming Chen, Wei-Ting Hung, Wan-Chun Chang, Chia-Wei Hsieh, Wen-Hung Chung, Joung-Liang Lan, Ning-Rong Gung, Yun-Shien Lee, Der-Yuan Chen, Shuen-Iu Hung

“…Patients with systemic pattern outcome were associated with elevated M-CSF and frequently observed in TT carriers. Our data suggest that genetic variants near CSF1 are associated with AOSD and the rs11102024 T allele links to higher M-CSF levels and systemic outcome. …”
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Multiparameter resting-state functional magnetic resonance imaging as an indicator of neuropsychological changes in Binswanger’s disease with mild cognitive impairment by Haiyi Zhang, Lu Zhang, Juan Lu, Jiajun Yue, Zhengzhen Yuan, Jidan Hu, Qi Yao, Yuting Fu, Guiquan Chen, Jiliang Fang, Jie Zhao

“…In summary, the results of our study suggest that patients diagnosed with BD-MCI display atypical activity across several brain regions. The observed changes in these areas encompass a range of functional networks. …”
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Fluoride exposure, personal susceptibility and osteoarticular degeneration: Evidence from farmers in the Yellow River Basin of Henan Province by Zichen Feng, Long Sun, Shu Niu, Bin Liu, Ruijie Ba, Guoqing Wang, Qing Sun, Chunxiang Li, Yan Wang, Fangfang Yu, Guoyu Zhou, Yue Ba

“…Thus, this study explored the relationships among fluoride exposure, genetic factors, physiological characteristics, lifestyle, and OAD risk, as well as the potential interactions among contributors in 593 adults from a cross-sectional study conducted in 2017. We observed that the OAD (n = 175) risk was increased with increasing urinary fluoride (UF) levels (OR=1.484; 95 %CI: 1.043, 2.111), age (OR=1.065; 95 %CI: 1.033, 1.098), and hip circumference (OR=1.069; 95 %CI: 1.014, 1.127), as well as a poor night sleep quality (OR=1.818; 95 %CI: 1.072, 3.084). …”
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A Cause Analysis of the High-Content Nitrogen and Low-Content Hydrocarbon in Shale Gas: A Case Study of the Early Cambrian in Xiuwu Basin, Yangtze Region by Yizhou Huang, Kun Zhang, Zhenxue Jiang, Yan Song, Shu Jiang, Chengzao Jia, Weiwei Liu, Ming Wen, Xuelian Xie, Tianlin Liu, Xin Li, Xin Wang, Xiaoxue Liu, Ye Zhang, Ling Tang

“…This study focused on the lower Cambrian shale in Xiuwu Basin, Lower Yangtze Region, with emphasis on the well Jiangye-1, using gas component analysis, stable nitrogen isotope analysis, overburden permeability tests in parallel and perpendicular directions, and FIB-HIM experiments, also combining with core description, outcrop observation, and seismic interpretation to explore the causes of the high-content nitrogen and low-content hydrocarbon in the lower Cambrian shale gas. …”
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Extracellular vimentin is a damage-associated molecular pattern protein serving as an agonist of TLR4 in human neutrophils by Łukasz Suprewicz, Krzysztof Fiedoruk, Karol Skłodowski, Evan Hutt, Magdalena Zakrzewska, Alicja Walewska, Piotr Deptuła, Agata Lesiak, Sławomir Okła, Peter A. Galie, Alison E. Patteson, Paul A. Janmey, Robert Bucki

“…Recent studies show the controlled release of vimentin into the extracellular environment, where it functions as a signaling molecule. Such observations are expanding our current knowledge of vimentin as a structural cellular component towards additional roles as an active participant in cell signaling. …”
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Genomic and resistome analysis of Salmonella enterica isolates from retail markets in Yichun city, China by Xiaowu Jiang, Abubakar Siddique, Li Chen, Lexin Zhu, Haiyang Zhou, Li Na, Chenghao Jia, Yan Li, Min Yue

“…The overall incidence of Salmonella was 9.4 %, with a higher contamination rate observed in pork at 13.5 %, followed by the retail environment at 7.69 %. …”
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Prevalence of dengue and leptospirosis coinfection and associated mortality rates: a systematic review and meta-analysis by Suraj Tiwari, Mahalaqua Nazli Khatib, Rekha MM, Mandeep Kaur, Girish Chandra Sharma, Puneet Sudan, K. Satyam Naidu, Rajesh Singh, Teena Vishwakarma, Sonam Puri, Muhammed Shabil, Anuradha Yadav, Takveer Singh, Sahil Khurana, Rachana Mehta, Prakasini Satapathy, Renu Sah, Abhay M Gaidhane, Ganesh Bushi

“…Conclusion This meta-analysis revealed a moderate prevalence and a notable mortality rate for dengue and leptospirosis co-infections, with significant variability observed across different studies. Further research into the immunopathology and the implementation of integrated surveillance systems could enhance the effectiveness of diagnosis and treatment strategies in regions where these diseases are endemic.…”
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The Role of Inflammatory Parameters and Antibody Seroconversion on COVID-19 Outcomes in Patients with Central Obesity by Syahidatul Wafa, Dicky Levenus Tahapary, Evy Yunihastuti, Heri Wibowo, Cleopas Martin Rumende, Kuntjoro Harimurti, Ketut Suastika, Farid Kurniawan, Rona Kartika, Tika Pradnjaparamita, Dante Saksono Harbuwono

“…The poor clinical outcome of hospitalization was observed. We used the Mann-Whitney test to analyse non-normally distributed data, and T-test for normally-distributed data. …”
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Characteristic of the active substance of the Saccharomyces cerevisiae preparation having radioprotective properties by G. S. Ritter, V. P. Nikolin, N. A. Popova, A. S. Proskurina, P. E. Kisaretova, O. S. Taranov, T. D. Dubatolova, E. V. Dolgova, E. A. Potter, S. S. Kirikovich, Y. R. Efremov, S. I. Bayborodin, M. V. Romanenko, M. I. Meschaninova, A. G. Venyaminova, N. A. Kolchanov, S. S. Bogachev

“…It was found that yeast RNA preparation has a prolonged radioprotective effect after irradiation by a lethal dose of 9.4 Gy. 100 % of animals survive on the 70th day of observation when irradiated 1 hour or 4 days after 7 mg RNA preparation injection, 60 % animals survive when irradiated on day 8 or 12. …”
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Aloe Emodin Reduces Cardiac Inflammation Induced by a High-Fat Diet through the TLR4 Signaling Pathway by Yingfu Chen, Burong Feng, Ye Yuan, Juan Hu, Wei Zhao, Huiwei Jiang, Wen Li, Ziyi Fan, Zhimin Du

“…We established a hyperlipidemia-induced cardiac inflammation model in rats and cells then administered AE and observed its effect on hyperlipidemia-induced cardiac inflammation. …”
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Physical Activity, Fatigue, and Sleep in People with Parkinson’s Disease: A Secondary per Protocol Analysis from an Intervention Trial by S. Coe, M. Franssen, J. Collett, D. Boyle, A. Meaney, R. Chantry, P. Esser, H. Izadi, H. Dawes

“…There was no impact on self-reported fatigue or sleep. Conclusion. The observed moderate effect on sedentary and light activities overnight could suggest an objective improvement in sleep patterns for individuals participating in both exercise and handwriting interventions. …”
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