Nationwide carrier screening for congenital adrenal hyperplasia: integrated approach of CYP21A2 pathogenic variant genotyping and comprehensive large gene deletion analysis by Yossawat Suwanlikit, Bhakbhoom Panthan, Pawares Chitayanan, Sommon Klumsathian, Angkana Charoenyingwattana, Wasun Chantratita, Objoon Trachoo

“…The concordance of pathogenic variant detection between ARMS-PCR and MS, as well as the consistency observed in molecular insights from qPCR and PCR-based RFLP, fortified the accuracy of our methodologies. …”
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Prevalence and predictors of sub-optimal laboratory monitoring of selected higher risk medicines in Irish general practice: a 5-year retrospective cohort study of community-dwellin... by Fiona Boland, Emma Wallace, Frank Moriarty, Tom Fahey, Caroline McCarthy, Ann Sinéad Doherty, Mark Feighery

“…Objectives To describe the prevalence of sub-optimal monitoring for selected higher-risk medicines in older community-dwelling adults and to evaluate patient characteristics and outcomes associated with sub-optimal monitoring.Study design Retrospective observational study (2011–2015) using historical general practice-based cohort data and linked dispensing data from a national pharmacy claims database.Setting Irish primary care.Participants 625 community-dwelling adults aged ≥70 years and prescribed at least one higher-risk medicine during the 5-year study period.Primary and secondary outcome measures The primary outcome was the prevalence of sub-optimal laboratory monitoring using a composite measure of published medication monitoring indicators, with a focus on commonly prescribed higher-risk medicines such as diuretics and anticoagulants. …”
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Effect of potent nucleos(t)ide analog on alpha fetoprotein changes and occurrence of hepatocellular carcinoma in patients with chronic hepatitis B by Qianqian Ma, Junzhao Ye, Ling Luo, Yanhong Sun, Wei Wang, Shiting Feng, Bing Liao, Bihui Zhong

“…Conclusions Similar AFP elevation and HCC development rates were observed in CHB patients treated with ETV or TDF. Elevated SWE and abnormal AFP at baseline were independent risk factors for abnormal AFP in CHB patients.…”
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Growth Traits and Yield Performance of Japonica Hybrid Rice Bred by the New Strategy in the Yangtze River Region of China by Yutiao Chen, Jiayu Song, Xiaofu Hong, Huaijie Zhang, Tiejun Hu, Guanglong Zhu

“…Moreover, significant quadratic relationships were observed between plant height at maturity and grain yield and between seedling dry weight and grain yield. …”
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Assessment of diabetes-specific eating disorder risk in adult patients with diabetes by Afruz Babayeva, Shovket Alishova, Gunay Mammadova, Meric Coskun, Ethem Turgay Cerit, Alev Eroglu Altinova, Mujde Akturk, Fusun Balos Toruner, Mehmet Ayhan Karakoc, Mehmet Muhittin Yalcin

“…Results Risk of DEB was observed in 35% of all individuals with diabetes and was higher in T2D (55% (n = 22)) than in T1D (25% (n = 20)) (p < 0.001). …”
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Understanding crystallinity indexes benchmarking concept from optimized parametric ionic liquid pretreatment using 1-ethyl-3-methylimidazolium Acetate [EMIM]Ac on oil palm biomass by Amizon Azizan, Rosmaria Abu Darim, Intan Suhada Azmi, Rafidah Jalil, Shareena Fairuz Abdul Manaf

“…The proposed optimized pretreatment variable region for lower CrI was observed and concluded to be approximately 48% [EMIM]Ac with a solid loading of 12% OPF-[EMIM]Ac at a temperature of 93 °C. …”
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Profiles of Killer Systems and Volatile Organic Compounds of Rowanberry and Rosehip-Inhabiting Yeasts Substantiate Implications for Biocontrol by Iglė Vepštaitė-Monstavičė, Juliana Lukša-Žebelovič, Violeta Apšegaitė, Raimondas Mozūraitis, Robertas Lisicinas, Ramunė Stanevičienė, Laima Blažytė-Čereškienė, Saulius Serva, Elena Servienė

“…Statistically significant differences between the individual VOCs were observed among killing phenotype-possessing vs. non-killer <i>S. paradoxus</i> yeasts, thus revealing the involvement of killer systems in multi-level biocontrol enablement. …”
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Comparison of various feed additives on nutrient digestibility, digestive enzyme activity, blood metabolite levels, and gut microbiota composition in japanese quail chicks by Hassan Saleh, Omid Jangjou, Mohammad Taher Mirakzehi, Seyedeh Hamideh Hosseni

“…However, no significant difference in lipase activity was observed among the various dietary supplements. The levels of LDL, TG, MDA, ALT, IgG, and IgM were influenced by the experimental treatments. …”
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On-farm hatching and contact with adult hen post hatch induce sex-dependent effects on performance, health and robustness in broiler chickens by Guilloteau, Laurence A, Bertin, Aline, Crochet, Sabine, Bagnard, Charlotte, Hondelatte, Alice, Ravon, Laure, Schouler, Catherine, Germain, Karine, Collin, Anne

“…An interaction between the effect of experimental rearing conditions and chicken sex was observed later for BW. In males, the OFH chickens were the heaviest compared to the other groups at D34 but not at D56. …”
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Changes in taste and odor sensitivities during repeated bicycle ergometer exercises by Masataka Narukawa, Kensuke Nojiri, Rina Matsuda, Momo Murata, Seiji Sakate, Sachiko Kuga, Hidetoshi Ue

“…On the other hand, no significant effect was observed on the perceived odor intensity of the isotonic beverages. …”
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Gambaran Klinis dan Endoskopi Saluran Cerna Bagian Atas Pasien Dispepsia di Bagian RSUP Dr. M. Djamil Padang by Citra Yuriana Putri, Arnelis ., Asterina .

“…The design of this research was an observational descriptive study. The subject of this study are consist of 54 patients with dyspepsia who have performed esophagogastro- duodenoscopy  (EGD) examination in Integrated Diagnostics Installation of Dr. …”
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Comparison of Machine Learning Methods and Conventional Logistic Regressions for Predicting Gestational Diabetes Using Routine Clinical Data: A Retrospective Cohort Study by Yunzhen Ye, Yu Xiong, Qiongjie Zhou, Jiangnan Wu, Xiaotian Li, Xirong Xiao

“…We performed a retrospective, observational study including women who attended their routine first hospital visits during early pregnancy and had Down’s syndrome screening at 16-20 gestational weeks in a tertiary maternity hospital in China from 2013.1.1 to 2017.12.31. …”
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Clonal Spread and Genetic Mechanisms Underpinning Ciprofloxacin Resistance in <i>Salmonella enteritidis</i> by Zengfeng Zhang, Hang Zhao, Chunlei Shi

“…The co-transfer of the PMQR gene <i>oqx</i>AB with the ESBL gene <i>bla</i>_CTX-M-14/55 on an IncHI2 plasmid with a size of ~245 kbp was observed through conjugation, highlighting the role of horizontal gene transfer in the dissemination of antibiotic resistance. …”
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Visual hermeneutics as a tool to introduce empathy and core physician attributes in doctor-patient relationship for first-year medical undergraduate students by Sushma Prabhath, Uma Kulkarni, Vani Lakshmi R., Bikash Patra, Eshwari K., Divya Arvind Prabhu, Kirtana R. Nayak

“…Hermeneutics, a method of interpretation, can play a vital role in introducing observational and reflective thinking skills. This study aimed to introduce empathy concepts and attributes of a good physician to first-year medical students through the use of paintings and visual hermeneutics to enhance their understanding of the doctor-patient relationship. …”
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Feasibility Aspects of Exploring Exercise-Induced Neuroplasticity in Parkinson’s Disease: A Pilot Randomized Controlled Trial by Hanna Johansson, Malin Freidle, Urban Ekman, Ellika Schalling, Breiffni Leavy, Per Svenningsson, Maria Hagströmer, Erika Franzén

“…Image quality was acceptable; however, diplopia and/or sleepiness were observed in several participants during MRI. With regard to dual-task gait performance, there appeared to be a ceiling effect of the cognitive tasks with seven participants scoring all correct answers at pretest. …”
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Effects of clinical stage, behavioral and psychological symptoms of dementia, and living arrangement on social distance towards people with dementia. by Kae Ito, Shuji Tsuda

“…At the severe stage, the lowest social distance was observed towards individuals living with their family without BPSD, whereas the highest was towards those living alone, exhibiting BPSD. …”
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Nutritional and General Awareness of Vitamin D Status among Adult Population in Sulaymaniyah Governorate, Kurdistan Region, Iraq: A Cross-Sectional Study by Reder Rafiq Mohammed Salih, Fadhluddin Nasruddin Shakor, Dalia Ardal Ali, Rafiq Mohammed Salih Rashid

“…A descriptive cross-sectional survey of Iraqi adults over 18 was performed with a collection of serum 25(OH)D result between June and September 2022. The observed serum vitamin D indicated that only 25% of the participant had healthy (>30 ng/ml) vitamin D levels. …”
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PENERAPAN MODEL LEARNING CYCLE 5E DENGAN PENDEKATAN SAINTIFIK UNTUK MENINGKATKAN SIKAP ILMIAH DAN HASIL BELAJAR SISWA PADA KONSEP USAHA DAN ENERGI by Sari Daulay, Dedy Hamdani, Desy Hanisa Putri

“…The instruments used were the observation sheet to describe the activities of teacher and students, questionnaire to describe students' scientific attitudes, and test sheet to describe learning outcomes of work and energy. …”
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The use of emergency medical services for palliative situations in Western Cape Province, South Africa: A retrospective, descriptive analysis of patient records by C Gage, B Spies, K Crombie, L Gwyther, W Stassen

“…To examine EMS use for palliative situations in the Western Cape (WC) Province of SA by describing frequency of intersection, patient characteristics and outcomes. Methods. An observational, descriptive, retrospective patient record review was employed at two hospitals with palliative care services in the WC. …”
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Investigation of geographic disparities and temporal changes of non-gestational diabetes-related emergency department visits in Florida: a retrospective ecological study by Md Marufuzzaman Khan, Agricola Odoi

“…Conclusions The study findings confirm geographic disparities of non-gestational diabetes-related ED visit rates in Florida with high-rate areas observed in the rural northern and south-central parts of the state. …”
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