Gut microbiota modulation via fecal microbiota transplantation mitigates hyperoxaluria and calcium oxalate crystal depositions induced by high oxalate diet by Lingyue An, Shujue Li, Zhenglin Chang, Min Lei, Zhican He, Peng Xu, Shike Zhang, Zheng Jiang, Muhammad Sarfaraz Iqbal, Xinyuan Sun, Hongxing Liu, Xiaolu Duan, Wenqi Wu

“…Here, we investigated the therapeutic efficacy of fecal microbiota transplantation (FMT) sourced from healthy rats fed with standard pellet diet against urinary oxalate excretion, renal damage and calcium oxalate (CaOx) crystal depositions via using hyperoxaluria rat models. We observed dose-dependent increases in urinary oxalate excretion and CaOx crystal depositions due to hyperoxaluria, accompanied by significant reductions in gut microbiota diversity characterized by shifts in Ruminococcaceae_UCG-014 and Parasutterella composition. …”
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Humoral and Cellular Immunity After Vaccination Against SARS-CoV-2 in Relapsing-Remitting Multiple Sclerosis Patients Treated with Interferon Beta and Dimethyl Fumarate by Marcin Bazylewicz, Monika Zajkowska, Monika Gudowska-Sawczuk, Rafał Kułakowski, Jan Mroczko, Dagmara Mirowska-Guzel, Joanna Kulikowska-Łoś, Agata Czarnowska, Barbara Mroczko, Jan Kochanowicz, Alina Kułakowska

“…No differences were observed in the case of subgroups in which sample collection was less than 200 days after vaccination when compared to the control group. …”
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High CD163 Expression on Classical Monocytes Is Associated with Immune Control of HBV Infection in Noncirrhotic Patients by Anna Parfieniuk-Kowerda, Kamil Grubczak, Andrzej Eljaszewicz, Magdalena Świderska, Magdalena Maciaszek, Anatol Panasiuk, Jerzy Jaroszewicz, Robert Flisiak, Marcin Moniuszko

“…Positive correlations between plasma sCD163 and ALT, as well as APRI, were observed. Plasma sTWEAK concentration was lower in CHB patients in comparison to patients with HBsAg/anti-HBs seroconversion. …”
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Association of Corticosteroid Inhaler Type with Saliva Microbiome in Moderate-to-Severe Pediatric Asthma by Amir Hossein Alizadeh Bahmani, Mahmoud I. Abdel-Aziz, Simone Hashimoto, Corinna Bang, Susanne Brandstetter, Paula Corcuera-Elosegui, Andre Franke, Mario Gorenjak, Susanne Harner, Parastoo Kheiroddin, Leyre López-Fernández, Anne H. Neerincx, Maria Pino-Yanes, Uroš Potočnik, Olaia Sardón-Prado, Antoaneta A. Toncheva, Christine Wolff, Michael Kabesch, Aletta D. Kraneveld, Susanne J. H. Vijverberg, Anke H. Maitland-van der Zee, on behalf of the SysPharmPediA consortium

“…<b>Results</b>: No significant difference was observed in α-diversity between the two groups. However, β-diversity analysis revealed significant differences between groups using both Bray–Curtis and weighted UniFrac methods (adjusted <i>p</i>-value = 0.015 and 0.044, respectively). …”
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The ILE462VAL polymorphism of the cytochrome P450 CYP1A1 gene among Tundra Nenets in Yamalo-Nenets Autonomous Okrug, Nganasans in the Taimyr Peninsula and Russians in Siberia by R. P. Tiis, L. P. Osipova, T. V. Churkina, L. E. Tabikhanova, D. V. Lichman, E. N. Voronina, M. L. Filipenko

“…Frequencies of the  462Val variant close to that in Nganasans have been observed in Greenland Inuits, native Americans as a whole and the Southern Chinese. …”
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Diagnostic Management and Surgical Treatment of Isolated Tricuspid Regurgitation by Arthur Cicupira Rodrigues de Assis, Gustavo Andre Boeing Boros, Lea Maria Macruz Ferreira Demarchi, Thiago Luis Scudeler, Paulo Cury Rezende

“…No signs of infection or vegetation nor disruption of strands were observed. This report illustrates a very rare case of symptomatic primary isolated severe tricuspid regurgitation caused by myxomatous degeneration of the leaflets. …”
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The effects of Tripterygium wilfordii Hook F on renal outcomes in type 2 diabetic kidney disease patients with severe proteinuria: a single-center cohort study by Yaqi Cheng, Yuhao Liu, Liling Lin, Danni Li, Liying Peng, Ke Zheng, Jianling Tao, Mingxi Li

“…Kaplan-Meier curves and Cox regression analyses were performed to analyze prognostic factors for renal outcomes.Results By the end of the follow-up, renal outcomes were observed in 23 and 11 patients in the non-TwHF and TwHF groups, respectively (p = 0.006). …”
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Body mass index and B‐lines on lung ultrasonography in chronic and acute heart failure by Philip Brainin, Brian Claggett, Eldrin F. Lewis, Kristin H. Dwyer, Allison A. Merz, Montane B. Silverman, Varsha Swamy, Tor Biering‐Sørensen, Jose Rivero, Susan Cheng, John J.V. McMurray, Scott D. Solomon, Elke Platz

“…For AHF, B‐line number declined to a lesser degree than NT‐proBNP concentration with increasing BMI (P = 0.020), and >6 B‐lines were observed in half of AHF patients with severe obesity. …”
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The relationship between stress levels and the habits of consuming high-sugar food among undergraduate students by Zulfa 'Azizah, Dittasari Putriana, Agil Dhiemitra Aulia Dewi

“…This study aims to investigate the relationship between stress levels and the consumption of high-sugar foods among students at Universitas 'Aisyiyah Yogyakarta (UNISA). This analytical observational research employed a cross-sectional design. …”
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Elevated Serum Levels of the Antiapoptotic Protein Decoy-Receptor 3 Are Associated with Advanced Liver Disease by Giorgos Bamias, Michalis Gizis, Ioanna Delladetsima, Eyfrosyni Laoudi, Spyros I. Siakavellas, Ioannis Koutsounas, Garyfallia Kaltsa, John Vlachogiannakos, Irene Vafiadis-Zouboulis, George L. Daikos, George V. Papatheodoridis, Spiros D. Ladas

“…In cirrhotic patients, significant positive correlations were observed between sDcR3 levels and markers of severity of hepatic impairment, including MELD score (r=0.653, P<0.001). …”
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Assessment of Protein Quality and Nutritional Characteristics of Commonly Consumed Pulses in the Caribbean Diet by Different In Vitro Assays by Daniel J. Thomas, Zhanhui Lu, Yolanda Brummer, Yan Zhu, Ronghua Liu, Lili Mats, Rong Tsao, D. Dan Ramdath, Matthew G. Nosworthy

“…However, notable differences in digestibility were observed: it was higher in static assays (pH-Drop and pH-Stat) than in the two-step digestibility assay. …”
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Evaluation of learning from Practical Obstetric Multi-Professional Training and its impact on patient outcomes in Australia using Kirkpatrick’s framework: a mixed methods study by Philip DeKoninck, Euan M Wallace, Debra Nestel, Arunaz Kumar, Sam Sturrock, Donna Lucey, Sally Stoyles, Jenny Morgan, Peter Neil, Michelle Schlipalius

“…Participants reported a positive learning experience and increase in confidence in managing emergency obstetric situations through the PROMPT programme, which was perceived as a realistic demonstration of the emergencies.Conclusion Participants reported an improvement of both clinical and non-technical skills highlighting principles of teamwork, communication, leadership and prioritisation in an emergency situation. An improvement was observed in management of postpartum haemorrhage, but no significant change was noted in clinical outcomes over a 2-year period after PROMPT. …”
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Insights on the effect of mega-carcass abundance on the population dynamics of a facultative scavenger predator and its prey by Sidous, Mellina, Cubaynes, Sarah, Gimenez, Olivier, Drouet-Hoguet, Nolwenn, Dray, Stéphane, Bollache, Loïc, Madhlamoto, Daphine, Ngwenya, Nobesuthu Adelaide, Fritz, Hervé, Valeix, Marion

“…We discuss why signals of prey and predator population dynamics decoupling are less likely to be observed in systems with a high diversity of prey, such as African savannas, and why inputs of mega-carcasses as pulsed resources hardly impacted top-down relationships in the long run. …”
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FadA antigen of Fusobacterium nucleatum: implications for ceRNA network in colorectal cancer and adenomatous polyps progression by Sama Rezasoltani, Elahe Shams, Moein Piroozkhah, Yaser Aidi, Mehdi Azizmohammad Looha, Parmida Bagheri, Roudabeh Behzadi Andouhjerdi, Amir Sadeghi, Leili Rejali, Ehsan Nazemalhosseini-Mojarad

“…Results Elevated expression levels of FadA, ANXA2, hsa-let-7a-2, and LINC00460 were observed in CRC specimens, followed by AP cases, in comparison to samples from normal individuals. …”
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Classification of Slovenian Dry-Cured Ham – Kraški pršut – According to Texture Profile by Mateja Lušnic Polak, Tomaž Polak, Mojca Kuhar, Iva Zahija Jazbec, Tadej Kaltnekar, Lea Demšar

“…Positive correlation (p≤0.05) was also observed between NPN and pastiness. These findings indicate the importance of supplier, mass of pork thighs, and production parameters for optimizing the texture of Kraški pršut.…”
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Have crops already reached peak suitability: assessing global climatic suitability decreases for crop cultivation by Vhiny-Guilley Mombo, Mathilde Duvallet, Michiel Schaeffer, Florent Baarsch

“…We applied the method to evaluate the effects of climate change under two climatic scenarios (SSP2-4.5 and SSP5-8.5), using an ensemble of five general circulation models, for nine crops (Arabica coffee, cassava, common beans, common wheat, maize, plantain, rice, sorghum and sugarcane) for four periods of time: past (1995–2014), present day (2015–2034), medium term (2040–2059), long term (2080–2099). We observed that the fraction of area with optimal suitability might be on a downward trajectory for coffee, cassava, beans, wheat and plantain, and could be halved by the end of the century. …”
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Improving health outcomes and quality at the subdistrict level: Evaluation of the ‘3 feet model’ in Waterberg District, Limpopo Province, South Africa by H Schneider, F Mukinda, J Cupido, J Wessels, P Kupa, P Leboho, N Nkoana, N Bosch, Y Pillay

“…Data sources combined ~100 hours of researcher participant observation, interviews with 14 health system actors, structured reflections by three subdistrict managers and information from the routine District Health Information System. …”
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Exocyst complex component 1 (Exoc1) loss in dormant oocyte disrupts c-KIT and growth differentiation factor (GDF9) subcellular localization and causes female infertility in mice by Chi Lieu Kim Nguyen, Yumeno Kuba, Hoai Thu Le, Hossam Hassan Shawki, Natsuki Mikami, Madoka Aoki, Nanako Yasuhara, Hayate Suzuki, Saori Mizuno-Iijima, Shinya Ayabe, Yuki Osawa, Tomoyuki Fujiyama, Tra Thi Huong Dinh, Miyuki Ishida, Yoko Daitoku, Yoko Tanimoto, Kazuya Murata, Woojin Kang, Masatsugu Ema, Yuji Hirao, Atsuo Ogura, Satoru Takahashi, Fumihiro Sugiyama, Seiya Mizuno

“…These abnormal phenotypes were also observed in oocytes depleted of exocyst complex members EXOC3 and EXOC7. …”
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Mental health disorder symptom changes among public safety personnel after emotional resilience skills training by R.N. Carleton, S. Sauer-Zavala, T.A. Teckchandani, K.Q. Maguire, L. Jamshidi, R.E. Shields, T.O. Afifi, J. Nisbet, K.L. Andrews, S.H. Stewart, A.J. Fletcher, R. Martin, R.S. MacPhee, J.C. MacDermid, T.M. Keane, A. Brunet, M. McCarron, L.M. Lix, N.A. Jones, G.P. Krätzig, J.P. Neary, G. Anderson, R. Ricciardelli, H. Cramm, J. Sareen, G.J.G. Asmundson

“…Results: There were reductions in self-report and clinical diagnostic interview positive screens for PTSD and other PTSI from pre- to post-training (ps < 0.05), with mental health sustained or improved at 1-year follow-up. Improvements were observed among firefighters (Cohen's d = 0.40 to 0.71), police (Cohen's d = 0.28 to 0.38), paramedics (Cohen's d = 0.20 to 0.56), and communicators (Cohen's d = 0.05 to 0.14). …”
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Dosimetry of automatic non-coplanar volumetric-modulated arc therapy for nasopharyngeal carcinoma by Kaiqiang Chen, Jihong Chen, Yanming Cheng, Danni Hong, Cairong Hu, Penggang Bai, Jinyong Lin, Yang Yang, Xiuchun Zhang

“…Moreover, the HA plans had better sparing, particularly for the optic chiasm, optic nerves, and parotid glands (P ​< ​0.05), while no statistically significant differences were observed for other critical structures such as the brainstem, spinal cord, and temporal lobes (P ​> ​0.05). …”
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