In vitro and in vivo investigations of selected varieties of Areca catechu L - Phytochemical analysis, antiulcer, and wound healing activity by R. Deveswaran, D.J. Madhu Kumar, V. Madhavan, Soma Chaki, Misbah Khan, Govind R. Kadambi, B.V. Basavaraj, J. Anbu

“…Cell line studies using human gingival fibroblasts demonstrated that higher doses of the extracts exhibited a mitogenic effect, with a plateau observed at higher concentrations. Lower concentrations showed maximum cell viability, reaching 80 % at 2.5 mg/mL. …”
Get full text

A CD36-based prediction model for sepsis-induced myocardial injury by Yun Xie, Hui Lv, Daonan Chen, Peijie Huang, Zhigang Zhou, Ruilan Wang

“…No significant differences in CD36 levels were observed between groups with lung and stomach infections or between Gram-positive and Gram-negative infection groups. …”
Get full text

Overexpression of Tear Inflammatory Cytokines as Additional Finding in Keratoconus Patients and Their First Degree Family Members by Ioana Catalina Ionescu, Catalina Gabriela Corbu, Cristiana Tanase, Gabriela Ionita, Cristina Nicula, Valeria Coviltir, Vasile Potop, Mihaela Constantin, Elena Codrici, Simona Mihai, Ionela Daniela Popescu, Ana-Maria Enciu, Dana Dascalescu, Miruna Burcel, Radu Ciuluvica, Liliana-Mary Voinea

“…We analyzed forty-eight participants in an observational cross-sectional study. The diagnosis of keratoconus had to be confirmed in addition to a minimum of 47 D corneal refractive power by corneal topography readings provided by a Placido-based topography system and analysis of the pattern: irregular astigmatism with an asymmetric “bow-tie.” …”
Get full text

Predicting dengue incidence in high-risk areas of China through the integration of Southeast Asian and local meteorological factors by Shaowei Sang, Yiguan Wang, Qiyong Liu, Peng Chen, Chuanxi Li, Anran Zhang

“…Large outbreaks occurred in 2014 (47,052 cases), 2019 (22,688 cases), and 2023 (19,936 cases), with peak incidence typically observed from August to October. The number of provinces reporting cases and outbreaks gradually linearly increased from 10 and 0 in 2005 to a peak of 30 and 11 in 2019, respectively, before declining in 2021 and 2022, then rebounding to 29 and 8 in 2023. …”
Get full text

Adhesion-induced MoS2 layer transfer via in-situ TEM-nanoindentation: Effects of curvature and substrate mediated residual stress by Jhih H. Liang, Mehdi Rouhani, J. David Schall, Takaaki Sato, Christopher Muratore, Nicholas R. Glavin, Robert W. Carpick, Yeau-Ren Jeng

“…Our findings, validated by Raman and X-ray photoelectron spectroscopy, reveal unique insights into MoS2's interfacial behavior. We observed a decreased structural order in MoS2 on sharper tips, particularly those without pre-deposition oxidation. …”
Get full text

METTL14-mediated m6A modification of DDIT4 promotes its mRNA stability in aging-related idiopathic pulmonary fibrosis by Dan Li, Li Qian, Yufeng Du, Lifang Liu, Ziyue Sun, Yongkang Han, Xiangrui Guo, Chao Shen, Zheng Zhang, Xuejun Liu

“…Increased peaks (3756) and decreased peaks (4712) were observed in the IPF group. The association analysis showed that 749 DEGs were affected by m6A methylation in IPF. …”
Get full text

Truncated NS1 Influenza A Virus Induces a Robust Antigen-Specific Tissue-Resident T-Cell Response and Promotes Inducible Bronchus-Associated Lymphoid Tissue Formation in Mice by Anna-Polina Shurygina, Marina Shuklina, Olga Ozhereleva, Ekaterina Romanovskaya-Romanko, Sofia Kovaleva, Andrej Egorov, Dmitry Lioznov, Marina Stukova

“…These effects are not observed in mice immunised with caPR8/NSfull or PR8/NSfull. …”
Get full text

Gas Hydrate Accumulation and Occurrence Associated with Cold Seep Systems in the Northern South China Sea: An Overview by Wei Zhang, Jinqiang Liang, Qianyong Liang, Jiangong Wei, Zhifeng Wan, Junxi Feng, Wei Huang, Jing Zhao, Miaomiao Meng, Wei Deng, Chongmin Chen

“…Based on high-resolution seismic data, subbottom profiles, in situ submergence observations, deep drilling and coring, and hydrate gas geochemical analyses, the geological and geophysical characteristics of these cold seep systems and their associated gas hydrate accumulations in the Qiongdongnan Basin, the Shenhu area, the Dongsha area, and the Taixinan Basin have been investigated. …”
Get full text

Cardiovascular Disease and Other Competing Causes of Death in Older Kidney Cancer Patients by Yinglan Liang, Liangjia Zeng, Ruoyun Zhou, Manting Feng, Linglong Liu, Kexin Chen, Jinqi Huang, Haowen Liang, Baixin He, Binghua Zhang, Yican Ying, Yuerong Chen, Tianwang Guan, Min Yi

“…Utilizing the standardized mortality ratios (SMRs) and absolute excess risks (AERs), we contrasted the risk of CVD and other competing causes of death in older kidney cancer patients to that observed in the general population. …”
Get full text

Impact of Mandatory Preoperative Dental Screening on Infective Endocarditis in Patients Undergoing Surgical Valve Replacement by Lytfi Krasniqi, MD, Poul Erik Mortensen, MD, Emil Johannes Ravn, MD, Marlene Tofterup, MD, Henrik Nissen, MD, PhD, Christian Juhl Terkelsen, MD, PhD, DMSCi, Niels Holmark Andersen, MD, PhD, DMSCi, Ivy Modrau, MD, DMSCi, Kasper Stokbro, DDS, PhD, Jonas A. Povlsen, MD, PhD, Oke Gerke, MSc, PhD, DMSCi, Jesper Hallas, MD, DMSCi, Marie-Annick Clavel, DVM, PhD, Lars Peter Schødt Riber, MD, PhD, DMSCi, Jordi Sanchez Dahl, MD, PhD, DMSCi

“…Methods: Patients undergoing SVR in Western Denmark from 2020 to 2022 were included in this observational study. Patients were considered based on 2 applied PDS practices: MPDS, and no routine referral to preoperative dental screening (NPDS). …”
Get full text

One Year Duration of Immune Response Following a 3rd Booster Dose of mRNA Vaccine Against COVID‐19 in 292 Patients With Hematological Malignancies in University Hospital Ostrava, C... by Ondrej Šušol, Barbora Šušolová, Ondřej Klempíř, Milan Navrátil, Jaromír Gumulec, Zdeněk Kořístek, Juraj Ďuraš, Michal Kaščák, Jana Mihályová, Lukáš Stejskal, Tomáš Jelínek, Petra Richterová, Lenka Szeligová, Hana Plonková, Jana Zuchnická, Barbora Dluhošová, Ivo Demel, David Buffa, Katarína Hradská, Tereza Popková, Ludmila Muroňová, Martin Lachnit, Klára Lančová, Roman Hájek

“…Lowest seroconversion was observed in CLL cohort (20/41, 48.8%), patients who received anti‐CD20 therapy < 6 months before vaccination (8/30, 26.7%) and BTK inhibitors (3/6, 50.0%). …”
Get full text

Serum Growth Differentiation Factor 15 is Negatively Associated with Leukocyte Telomere Length by Jie Yu, Yiwen Liu, Huabing Zhang, Fan Ping, Wei Li, Lingling Xu, Yuxiu Li

“…In correlation analysis, GDF15 was positively correlated with age, while LTL and mtDNAcn were negatively correlated with age.After adjusting for confounding factors,GDF15 was negatively associated with LTL (β = −0.120, 95%CI [−0.197, −0.042], p = 0.003) and the association was linear(p for nonlinear = 0.645), while the negative association between GDF15 and mtDNAcn did not reach significance.In the stratified analyses,the negative associations between GDF15 and LTL were more prominent in women, overweight individuals, or subjects with abnormal glucose tolerance (AGT), but similar results were observed in younger and older subjects. Conclusions: This study found a linear negative association between GDF 15 and LTL,which was more prominent in women, overweight or AGT subjects.These results supported that GDF15 might be a reliable biomarker of aging.…”
Get full text

Metabolic Syndrome and Its Components Predict the Risk of Type 2 Diabetes Mellitus in the Mainland Chinese: A 3-Year Cohort Study by Kun Wang, Qun-Fang Yang, Xing-Lin Chen, Yu-Wei Liu, Sheng-Shuai Shan, Hua-Bo Zheng, Xiao-Fang Zhao, Chang-Zhong Chen, Cheng-Yun Liu

“…Calibration curves revealed good agreement between prediction and observation results in males; however, the model could overestimate the risk when the predicted probability is >40% in females. …”
Get full text

Black Carbon Exposure Characteristics in Diesel Engine Vehicle-related Jobs by Sangjun Choi, Ju-Hyun Park, Won Kim, Seung Won Kim, Kyong-Hui Lee, Taejin Chung, Jihoon Park, Seung-Hun Ryu, Jungah Shin, Dong-Hee Koh, Dong-Uk Park

“…We then categorized and analyzed 71,987 of these 1-min observations based on four potential exposure determinants: the operation of a diesel engine vehicle (yes or no), proximity to the source of BC (near or far), location of the workplace (indoor or outdoor), and type of work (moving or stationary). …”
Get full text

Efficacy of natural and synthetic inhibitors in the elimination of viruses in potato (<i>Solanum tuberosum</i> L.) by E. V. Shishchenko, I. V. Kim, E. N. Barsukova, I. M. Yermak, A. O. Kravchenko, A. G. Klykov

“…Natural polysaccharides – carrageenans – were observed to have a significant antiviral effect, so their use in agricultural biotechnology might be promising for new experiments. …”
Get full text

Effect of a bimetal Mn/Zn catalyst supported on activated carbon for selective oxidation of ethyl lactate to ethyl pyruvate by G. Madhanagopal, K. Premalatha, P.N. Poovizhi, V. Sumithra, S. Mahalingam, L. Guganathan, S. Sivakumar, A. Subramani, P. Tamizhdurai

“…Interestingly, the formation of additional acidic compounds beyond the desired reaction time was observed, suggesting potential side reactions. Further investigation into these side reactions is necessary for complete optimization. …”
Get full text

Seasonal trends of pyogenic spondylodiscitis in Japan: a nationwide inpatient database study by Takayuki Motoyoshi, Takahisa Ogawa, Kazuyuki Fukushima, Satoshi Kutsuna, Haggai Schermann, Kiyohide Fushimi, Toshitaka Yoshii

“…Admissions peaked in spring (n = 18,076) and were lowest in winter (n = 17,565), although no seasonal trend was observed among those with MRSA infection. The average age of patients was 71.05 years, and 60.9 % of patients were male. …”
Get full text

Proteomic, metabolomic and lipidomic profiles in community acquired pneumonia for differentiating viral and bacterial infections by Samuel Rischke, Robert Gurke, Ann-Sophie Zielbauer, Nicole Ziegler, Lisa Hahnefeld, Michaela Köhm, Aimo Kannt, Maria JGT Vehreschild, Gerd Geisslinger, Gernot Rohde, Carla Bellinghausen, Frank Behrens, CAPNETZ Study group

“…Through comparison of the bacterial and viral pathogen groups, distinct signatures were observed in the plasma profiles. Notably, linoleic acid-derived inflammation signaling metabolites (EpOME and DiHOME) were increased in viral CAP compared to bacterial CAP. …”
Get full text

The Length-Weight Relationship and Condition Factors of Bullet Tuna Landed at the Tanjung Luar Fishing Port, Indonesia by Evron Asrial, Yasir Arapat, Usma Kurniawan Hadi, Lalu A.T.T.W.S Kalih, Mita Ayu Liliyanti, Erwin Rosadi, Ruly Isfatul Khasanah, Ishani Nelunika Rathnayake

“…Meanwhile, the data were collected from July to September 2020 (2nd transitional season) at the Tanjung Luar Fishing Port, East Lombok and a dependent survey method was adopted with sampling, interview, observation, and documentation techniques. Fork length and body weight data were used to estimate the length and weight relationship, growth pattern, condition factor, fish age group, and catch worth. …”
Get full text

Adaptive radiotherapy in locally advanced head and neck cancer: The importance of reduced margins by Hedda Enocson, André Haraldsson, Per Engström, Sofie Ceberg, Maria Gebre-Medhin, Gabriel Adrian, Per Munck af Rosenschöld

“…Significant reductions in mean doses to OARs were observed for PTV = 2 mm ART-plans: 4.1 Gy for parotid, 2.6 Gy for submandibular, 3.3 Gy for oral cavity, 4.0 Gy for esophagus, and 3.8 Gy for larynx. …”
Get full text