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27501
Protecting the American dream for socially vulnerable families: An evaluation of state-level policies to improve housing security and protect mobile home communities
Published 2025-06-01“…A substantial lag in policy implementation was observed. Notably, the infrastructure necessary to implement and monitor adherence to the new policies had to be developed. …”
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27502
lncRNA SNHG15 as a ceRNA modulates Osteoclast Differentiation, Proliferation, and Metastasis by Sponging miR-381-3p/NEK2 Axis
Published 2022-01-01“…The expressions of SNHG15, miR-381-3p, and never in mitosis-related kinase 2 (NEK2) mRNA were detected by real-time quantitative polymerase chain reaction (RT-qPCR); Western blot detected NEK2 and osteoclast markers (Cathepsin K, CTSK), matrix metalloproteinase 9 (MMP9), nuclear factor of activated T cell 2 (NFAT2), and tartrate-resistant acid phosphatase (TRAP) protein levels; cell proliferation was detected by Cell Counting Kit-8 (CCK-8), and the formation of osteoclasts was observed by TRAP staining; the F-actin skeleton was stained with tetramethylrhodamine isothiocyanate (TRITC) phalloidin; cell migration rate was detected by Transwell; dual-luciferase reporter gene assay and RNA-binding protein immunoprecipitation (RIP) assay verified the targeting relationship between miR-381-3p, SNHG15, and NEK2. …”
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27503
Participatory epidemiological approaches for risk assessment of bed bug (Insecta: Hemiptera: Cimicidae) infestation in public hospitals in the city of Faisalabad, Punjab, Pakistan
Published 2025-02-01“…Among administrative divisions (tehsils) in the city of Faisalabad, Tehsil Sadar had the highest number of participants with itching or skin irritation (35.48%), while Tehsil Chak Jhumra had the lowest number (24.62%). Most observations of bed bugs by patients were in their beds (10.42%), with chairs (3.91%) being the second most reported location. …”
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27504
<i>o</i>-Halogenation and -Alkoxylation of Phenylglycine Derivatives by Pd-Mediated C-H Functionalization: Scope and Limitations
Published 2025-01-01“…A partial loss of the enantiomeric excess is observed when the starting phenylglycine is enantiomerically pure, this arising from the formation of bridging azavinylidene (<b>6</b>) and imine intermediate species (<b>7</b>), which were characterized by X-ray diffraction methods.…”
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27505
Association between nutritional inflammation index and diabetic foot ulcers: a population-based study
Published 2025-01-01“…Moreover, an L-shaped non-linear link was observed. The turning point was at 3.09. Left of the inflection point, the relationship was negatively correlated. …”
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27506
Treatment and prescribing trends of antihypertensive drugs in 2.7 million UK primary care patients over 31 years: a population-based cohort study
Published 2022-06-01“…The prevalence of primary care patients with antihypertensive drug prescriptions increased from 7.8% (1988) to 21.9% (2018) and was observed for all major classes except thiazide diuretics. …”
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27507
Glucometabolic-Related Genes as Diagnostic Biomarkers and Therapeutic Targets for Alzheimer’s Disease and Type 2 Diabetes Mellitus: A Bioinformatics Analysis
Published 2024-01-01“…Similarly, in the T2DM murine model, elevated expression levels of G6pd, Pfkl, Eno3, and Pgd were observed. Conclusion. Our rigorous research sheds light on the molecular interconnections between AD and T2DM from a glucometabolic perspective, revealing new opportunities for pharmacological innovation and therapeutic approaches. …”
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27508
Diabetes and Hemoglobin A1c as Risk Factors for Nosocomial Infections in Critically Ill Patients
Published 2013-01-01“…Methods. Prospective observational study; patients were recruited from the intensive care unit (ICU) of a general district hospital between 2010 and 2012. …”
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27509
Composite cardiovascular risk factor control in US adults with diabetes and relation to social determinants of health: The All of Us research program
Published 2025-03-01“…Significant disparities were observed across race/ethnicity, sex, and socioeconomic lines with 43.1 % of Asian participants at control for ≥3 RFs compared to 21.1 % of non-Hispanic black participants. …”
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27510
Clinical Significance of Peripheral Blood T Lymphocyte Subsets in Helicobacter pylori-Infected Patients
Published 2012-01-01“…Tregs did not decrease, but the activation of humoral immunity and Th2 polarization were observed in the peripheral blood of H. pylori-infected patients. …”
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27511
Short-term outcome of endovascular stenting for symptomatic vertebrobasilar stenosis
Published 2025-01-01“…The most prevalent kind of stenosis observed was atherosclerosis, affecting 11 patients (64.7%), followed by dissection in 6 patients (35.2%). …”
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27512
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27513
Targeted generative data augmentation for automatic metastases detection from free-text radiology reports
Published 2025-02-01“…In our experiments, data augmentation improved the average F1-score by 2.3, 3.5, and 3.9 points for lung, liver, and adrenal glands, the organs for which we had access to expert-annotated data. This observation suggests that Llama3, which has not been specifically tailored to this task or clinical data in general, can generate high-quality synthetic data through paraphrasing in the clinical context. …”
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27514
Anti-SARS-Cov-2 S-RBD IgG Formed after BNT162b2 Vaccination Can Bind C1q and Activate Complement
Published 2022-01-01“…The anti-RBD IgG formed following either vaccine bound C1q, but significantly more C1q binding was observed in participants who received BNT162b2. Subsequently, C5b-9 formation was significantly higher in participants who received BNT162b2, while no significant difference in C5b-9 formation was found between the nonvaccinated and BBIBP-CorV groups. …”
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27515
Breeding value of prolific maize varieties with nicking of parental lines
Published 2019-01-01“…Iltis (basyonym Euchlaena mexicana Schrad.)) and eastern gamagrass (Tripsacum dactyloides L.).Materials and methods. Phenological observations were conducted according to conventional procedures. …”
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27516
Association between individual urinary iodine concentrations in pregnant women and maternal/newborn outcomes
Published 2025-01-01“…With low or very low certainty of the evidence, no difference in the incidence of miscarriage (RR: 0.87, 95% CI: 0.64–1.18, 6 studies, 4855 participants), maternal hypothyroidism (RR: 1.05, 95% CI: 0.68–1.60, 10 studies, 11,773 participants), preterm birth (RR: 1.20, 95% CI: 0.97–1.48, 13 studies, 15,644 participants), stillbirths (RR: 0.79, 95% CI: 0.34–1.82, 6 studies, 3406 participants), low birth weight (RR: 1.25, 95% CI: 0.88–1.78, 10 studies, 10,775 participants) and small for gestational age (RR: 1.11, 95% CI: 0.90–1.37, 5 studies, 4266 participants) was observed between the two groups. Conclusion: In pregnant women, individual diagnosis of UIC <150 μg/L was not associated with adverse maternal and neonatal outcomes, emphasizing UIC as a limited method to assess individual iodine status during pregnancy.…”
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27517
Polypharmacy and anticholinergic burden scales in older adults: a cross-sectional study among psychiatric outpatients in a tertiary care hospital
Published 2025-01-01“…Univariate analysis demonstrated that all anticholinergic risk assessment scales were closely correlated with polypharmacy, with the strongest association observed for the Anticholinergic Load Scale (ALS) (Odds Ratio = 4.3; p < 0.001). …”
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27518
Forensic-medical determination of the severity of closed injuries of the hyoid-laryngeal complex according to the data of a specialized clinic
Published 2023-09-01“…The severity of injuries of the hyoid-laryngeal complex was determined from a forensic-medical point of view based on the observations of patients in a specialized hospital. Injuries of the hyoid-laryngeal complex in 3 (4.8%) patients with the occurrence of life-threatening phenomena, namely acute respiratory failure, were assessed as serious ones. …”
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27519
Predicting academic procrastination of students based on academic self-efficacy and emotional regulation difficulties
Published 2025-01-01“…A statistically significant correlation was observed between students’ academic procrastination and academic self-efficacy (r = -0.648, p < 0.001) and the difficulty in emotional regulation (r = 0.701, p < 0.001). …”
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27520
Incidence and risk factors for mortality of vertebral osteomyelitis: a retrospective analysis using the Japanese diagnosis procedure combination database
Published 2013-03-01“…Objective To examine the incidence of vertebral osteomyelitis (VO) and the clinical features of VO focusing on risk factors for death using a Japanese nationwide administrative database.Design Retrospective observational study.Setting Hospitals adopting the Diagnosis Procedure Combination system during 2007–2010.Participants We identified 7118 patients who were diagnosed with VO (International Classification of Diseases, 10th Revision codes: A18.0, M46.4, M46.5, M46.8, M46.9, M48.9 and M49.3, checked with the detailed diagnoses in each case and all other codes indicating the presence of a specific infection) and hospitalised between July and December, 2007–2010, using the Japanese Diagnosis Procedure Combination database.Main outcome measures The annual incidence of VO was estimated. …”
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