Characteristics and Outcomes of Younger Adults with Embolic Stroke of Undetermined Source (ESUS): A Retrospective Study by Ali M. Al Khathaami, Bayan Al Bdah, Abdulmjeed Alnosair, Abdulkarim Alturki, Rayan Alrebdi, Shorug Alwayili, Sulaiman Alhamzah, Fahad A. M. AlKhathaami, Nasser Alotaibi

“…There was no significant difference in poor outcome at discharge (defined as mRS > 2), which was observed in 17.9% of younger adults and 28.7% of older adults. …”
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Squared diffusion-weighted imaging for improving the detection of clinically significant prostate cancer by Birte Valentin, Lars Schimmöller, Matthias Boschheidgen, Tim Ullrich, Thomas Andreas Thiel, Alexandra Ljimani, Jan Philipp Radtke, Thomas Benkert, Peter Albers, Gerald Antoch, Hans-Jörg Wittsack, Michael Quentin

“…After post-processing, a significant improvement in the subjective assessment of image quality was observed for rs-EPI b1000 (p < 0.001), rs-EPI b1800 (p < 0.001) and z-EPI b1000 (p < 0.001). …”
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Are there benefits of culture-based detection of Mycobacterium avium spp paratuberculosis over histopathology? by Motlatso T. Hlokwe, Nomawethu S. Masina, Boitumelo Letsoko, Sewellyn C. Davey, Anita L. Michel

“…However, an inhibitory effect on the MAP isolation rate observed when the antibiotic cocktail was added to the culture medium warrants further investigation. …”
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Establishing rabbit critical-size bone defects to evaluate the bone-regeneration potential of porous calcium phosphate ceramics by Wei Lei, Yan Wu, Yan Wu, Hao Yuan, Ping He, Jingqi Wu, Jingrong Chen, Yuxiao Liu, Hongmei Zhang, Joost D. de Bruijn, Xuerong Xiang, Ping Ji, Huipin Yuan, Huipin Yuan, Mingzheng Li

“…No bone bridging (i.e., union) was observed in the BCP implants at 12 weeks, whereas 80% of BCP implants (four out of five) achieved union by 24 weeks. …”
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Malignant phyllodes tumors with sarcomatous components: A histopathologic and molecular study by Ting Lei, Yunjie Song, Zhiyi Shen, Yongqiang Shi, Cunyan Xia, Xu Deng, Wenyue Da, Yan Peng, Qing Li

“…A notably high frequency of mutations was observed in several key genes within MPTs exhibiting sarcomatous components: TP53 (n = 6, 75.0 %), MUC16 (n = 4, 50.0 %), PTCH1 (n = 3, 37.5 %), and APC (n = 3, 37.5 %). …”
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Characterization of rectus femoris lesions in knee osteoarthritis at different stages and the effect of ultrasound-guided acupotomy by Wen-Ying Yu, Wen-Ying Yu, Jing Liu, Jing Liu, Ze-Hao Lin, Ze-Hao Lin, Hong Liu, Hong Liu, Liang-Zhi Zhang, Liang-Zhi Zhang, Xiang-Long Feng, Xiang-Long Feng, Zhong-Biao Xiu, Zhong-Biao Xiu, Zhong-Biao Xiu

“…Ultrasonography was used to record the elastic modulus and cross-sectional area of the rectus femoris muscle, and morphology was used to observe the ultramicroscopic changes in the rectus femoris muscle and assess the degree of fibrosis. …”
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Production of organic fertilizer using pleurotus sp. as a process accelerator by A. Medina-Buelvas, A. Garcia-Guan, B. Barraza-Amador, E. Espinosa-Fuente, M. Del Castillo-Cabrales, K. Mendez-Gutiérrez, N. Rosales-Hernández

“…Regarding the effect of the fertilizer on the development of corn seedlings, a positive effect was observed compared to the control. Otherwise, in the composting process, the fungus significantly accelerates the process and at the same time shows an overgrowth.…”
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The Role of Butirprost^® as an Adjuvant in Enhancing the Effect of Antibiotics in Patients Affected by Chronic Bacterial Prostatitis: A Randomized Prospective Trial by Felice Crocetto, Armando Calogero, Michele Santangelo, Agostino Fernicola, Filippo Varlese, Benito Fabio Mirto, Fabio Machiella, Alfonso Falcone, Giovanni Pagano, Fabrizio Dinacci, Gaetano Giampaglia, Domenico Varriale, Francesco Trama, Salvatore Iaconis, Francesco Del Giudice, Gian Maria Busetto, Matteo Ferro, Francesco Lasorsa, Giuseppe Lucarelli, Ciro Imbimbo, Biagio Barone

“…Notable improvements were observed in pain, urinary symptoms, and QoL. <i>Conclusions</i>: The administration of Butirprost^® along with fluoroquinolones resulted in a significant improvement in pain, urinary symptoms, and quality of life along with improvements in both IPSS and NIH-CPSI scores, in patients affected by chronic bacterial prostatitis compared with fluoroquinolones alone.…”
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Influence of the Multifunctional Biological Product Phytop 26.82 on the Growth and Development of Seed Potatoes by Vladislava Maslennikova, Vera Tsvetkova, Andrey Petrov, Rinat Galeev, Maxim Shulga, Natalia Gavrilets, Sergey Ryumkin, Anastasia Shulga, Evgeniy Ryadskiy, Kristina Koloshina, Inga Ryumkina

“…The morphological parameters of the Kemerovchanin potato variety were observed during the course of this study. The results of the study showed that the microbial mixture Phytop 26.82 made it possible to increase the biomass of plants by 1.5–1.8 times due to an increase in the length of the aerial part (by 10%), the number of stems (1.2–1.7 times), and the number of stolons (1.5–1.6 times) compared to control. …”
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Phthalates esters disrupt demersal fish behavior: Unveiling the brain-gut axis impact by Liuqingqing Liu, Xinyao Li, Xianxiang Luo, Xiao Wang, Linjia Liu, Zixi Yuan, Cuizhu Sun, Hao Zheng, Elvis Genbo Xu, Fengmin Li

“…After a 20-day foodborne exposure at a low marine environmental concentration (1.0 μg g−1), we observed that all three PAEs significantly increased the thigmotaxis (behavioral tendency to stay close to physical boundaries) and mobility of juvenile fish by 28.2–59.4 % and 23.3–74.5 %, respectively, indicating anxiety-like behavior of fish. …”
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Impact in Clinical Practice of the European Medicines Agency Health Alert About the Restriction of the Use of JAK Inhibitors by Elisabet Castañeda-Estévez, Cristina Vergara-Dangond, Martina Steiner, Maria Beatriz Paredes-Romero, Ana Esteban-Vázquez, Tatiana Cobo-Ibañez, Laura Trives-Folguera, Maria Liz Romero-Bogado, Isabel De La Cámara-Fernández, Patricia Richi-Alberti, Ana Acosta-Alfaro, Iría De la Osa-Subtil, Santiago Muñoz-Fernández

“…<b>Results:</b> In this retrospective, observational study, 101 patients were analysed, predominantly women (72.3%), with a mean age of 57.6 years. …”
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Modified Trochanteric Flip Osteotomy in Varus Intertrochanteric Osteotomy for Treatment of Legg–Calvé–Perthes Disease by Andrea Laufer, Carina Antfang, Georg Gosheger, Adrien Frommer, Gregor Toporowski, Henning Tretow, Robert Roedl, Bjoern Vogt

“…Radiographically, consolidation at the osteotomy site was observed in all cases with no delayed union or non-union. …”
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Research on the numerical simulation of dynamic explosion shock wave propagation characteristics between floors by Ke Wu, Bo Chen, Hao Li, Yunfeng Zhang, Damin Zhang, Yixuan Wu, Yaguang Sui

“…In scenarios involving an equivalent charge of 400 kg and initial velocities ranging up to 1200 m/s, it was observed that shock waves propagate as partially spherical wavefronts within a distance of 15 m between floors; beyond this range, they evolve into nearly planar wavefront propagation. …”
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Fasting Plasma Glucose Indicates Reversibility of the Acute Insulin Response after Short-Term Intensive Insulin Therapy in Patients with Various Duration of Type 2 Diabetes by Liehua Liu, Siyue Yang, Jianbin Liu, Hai Li, Juan Liu, Xiaopei Cao, Haipeng Xiao, Yanbing Li

“…After the therapy, AIR increased from −16.7 (−117.4, 52.4) pmol/L·min to 178.7 (31.8, 390.7) pmol/L·min (P<0.001) while hyperglycemia was alleviated; this improvement was observed in all disease duration categories. AIR was almost absent when fasting plasma glucose (FPG) > 10 mmol/L, while both AIR (R=−0.53, P<0.001) and its improvement from baseline (△AIR, R=−0.52, P<0.001) were negatively associated with FPG after SIIT when FPG < 10 mmol/L. …”
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Diagnosis and treatment of thyroblastoma: a case report and review of literature by Xiting Chen, Xiting Chen, Lijuan Xiong, Lijuan Xiong, Hongling Liu, Haoqiang Wang, Donghai Cheng, Wei Wang, Wenyuan He, Bo Xie, Juan Zhou

“…This classification was based on the observation that the tumor presents with independent primitive multilineage elements and is frequently associated with DICER1 hotspot mutations.The objective of this study was to explore and investigate the clinicopathologic characteristics, molecular features and treatment strategies of patients with thyroblastoma, followed by a review of the previous relevant literature.MethodsThe clinical manifestations, pathological characteristics, molecular features and treatment strategies of the initial case of thyroblastoma pathologically confirmed in China were analyzed.ResultsThe tumor was revealed to have high invasive potential, rapid disease progression, and primitive multilineage elements of pathology, including immature thyroid epithelium, spindled mesenchymal proliferations, and neuroepithelial blastema. …”
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Effects of dietary supplementation with fish-derived Bacillus amyloliquefaciens AV5 on growth status, immune response, microbiota, and intestinal health of Nile tilapia (Oreochromi... by Vicent Michael Shija, Huapu Chen, Yi Li, Lishuko Ng’onga, Kwaku Amoah, Zhong Yong, Junxi Chen, Yu Dapeng, Robert Mkuye, Jia Cai

“…Improved intestinal morphology was observed in the G2 group. In G2, the fish livers changed from abnormally shaped to normally shaped nuclei and the gaps within the liver tissues decreased. …”
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Lesion-specific coronary artery calcium score to predict stent underexpansion by Wentao Yang, Ke Xu, Xi Fu, Weifeng Zhang, Ziyong Hao, Zhenchi Sang, Lisheng Jiang, Xingbiao Qiu, Shengxian Tu, Linghong Shen, Ben He

“…We aimed to determine the association between lesion-specific CAC score and stent underexpansion.MethodsIn this retrospective observational study, we included 416 lesions from 359 patients who underwent intravascular ultrasound (IVUS)-guided stent implantation. …”
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Immunogenicity and safety of a live attenuated varicella vaccine in children aged 1 to 12 years: A double-blind, randomized, parallel-controlled phase III clinical trial in China by Shiyuan Wang, Yang Zhang, Guifan Li, Jinhui Shi, Xianyun Chang, Hao Zhang, Fengcai Zhu, Jingxin Li, Kai Chu, Jinfang Sun

“…Adverse events (AEs) observed within 42 days after vaccination and serious adverse events (SAEs) within six months after vaccination were recorded. …”
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Study of long-acting vs daily growth hormone: peak levels, AUC, action duration, and IGF-1 by Ashraf Soliman, Fawzia Alyafei, Nada Alaaraj, Noor Hamed, Shayma Mohamed, Ahmed Elawwa, Vincenzo De Sanctis

“…Significant intra- and interindividual variability in GH uptake after injection has been observed, with higher GH concentrations correlating with increased IGF-1 levels and growth response. …”
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Endoscopic Submucosal Dissection for Gastric Subepithelial Tumors: A Single-Center Experience by Jin Sung Lee, Gwang Ha Kim, Do Youn Park, Jong Min Yoon, Tae Wook Kim, Jong Hun Seo, Bong Eun Lee, Geun Am Song

“…Procedure-related bleeding and perforation rates were both 4%. No recurrence was observed in patients with complete resection at a median follow-up period of 29 months (range: 7–83 months). …”
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