Effects of GABA Supplementation on Intestinal SIgA Secretion and Gut Microbiota in the Healthy and ETEC-Infected Weanling Piglets by Yuanyuan Zhao, Jing Wang, Hao Wang, Yonggang Huang, Ming Qi, Simeng Liao, Peng Bin, Yulong Yin

“…We found that, in both the normal and ETEC-infected piglets, jejunal SIgA secretion and expression of some cytokines, such as IL-4, IL-13, and IL-17, were increased by GABA supplementation. Meanwhile, we observed that some low-abundance microbes, like Enterococcus and Bacteroidetes, were markedly increased in GABA-supplemented groups. …”
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Comparison of metabarcoding taxonomic markers to describe fungal communities in fermented foods by Rué, Olivier, Coton, Monika, Dugat-Bony, Eric, Howell, Kate, Irlinger, Françoise, Legras, Jean-Luc, Loux, Valentin, Michel, Elisa, Mounier, Jérôme, Neuvéglise, Cécile, Sicard, Delphine

“…Between ITS1 and ITS2, differences in the best marker were observed according to the studied ecosystem. While ITS2 is best suited to characterize cheese, wine and fermented meat communities, ITS1 performs better for sourdough bread communities. …”
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Functional Analysis of DNMT1 SNPs (rs2228611 and rs2114724) Associated with Schizophrenia by Sonal Saxena, Pranay Amruth Maroju, Sumana Choudhury, Vidhya Chitta Voina, Poonam Naik, Kavitha Gowdhaman, Poornima Kkani, Kiranmai Chennoju, S. Ganesh Kumar, C. Ramasubramanian, G. Prasad Rao, Trinath Jamma, Kumar Pranav Narayan, K. Naga Mohan

“…When haplotype analysis of both loci was performed, we observed a significant association of T/T–T/T and T/T–C/T (P = 0.04) haplotypes with SZ. …”
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Acute Effects of Ketamine Infusion on Postoperative Mood Scores in Patients Undergoing Dilation and Curettage: A Randomized Double-Blind Controlled Study by Raham Hasan Mostafa, Ahmed Mohamed Khamis, Ashraf Nabil Saleh, Yehia Mamdouh Hassan Mekki, Mohamed Mohamed Kamal, Ismail Mohammed Ibrahim, Mohamed Abdulmohsen Abdulnaiem Ismaiel

“…Ketamine group patients showed higher sedation score and increased, although self-limiting, psychedelic phenomena than the control group. Conclusion. Observed data here support an acute effect of ketamine on mood but any further claim will be speculative. …”
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Predictive accuracy of the Violence Risk Assessment Checklist for Youth in acute institutions: A prospective naturalistic multicenter study by Anniken Lucia Willumsen Laake, John Olav Roaldset, Tonje Lossius Husum, Stål Kapstø Bjørkly, Carina Chudiakow Gustavsen, Sara Teresia Grenabo, Øyvind Lockertsen

“…Methods A prospective, naturalistic observational study design was employed. V-RISK-Y was administered for youth admitted to four acute inpatient psychiatric units and four acute residential youth care institutions. …”
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A novel agricultural drought index based on multi-source remote sensing data and interpretable machine learning by Hao Chen, Ni Yang, Xuanhua Song, Chunhua Lu, Menglan Lu, Tan Chen, Shulin Deng

“…The results show that IMLDI has a higher spatial and temporal consistency with standardized precipitation evapotranspiration index, can better reflect the real-world observed drought-affected cropland areas and gross primary production, and can also well describe the evolutions of 2009/2010 and 2019 drought events in the eastern parts of China, indicating higher drought monitoring performance of IMLDI. …”
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Research on the movement process of erosion-denudation type debris flow in middle-low mountains based on particle algorithm model by Xiaofeng He, Yongfeng Gong, Jinkai Yan, Shichang Gao, Zheng He, Gang Zhang, Guorui Wang, Zhiyong Hu, Hui Wang

“…Under normal conditions, the final average deposition thickness of the debris flow was 8.9 m, which was thicker than the 8.3 m observed under extreme conditions. Regarding movement speed, the debris flow initially accelerated and then decelerated, with the extreme condition resulting in a greater travel distance compared to the normal condition. …”
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Familial Hypercholesterolemia: Genetics, Symptoms, Diagnosis and Treatment - A Literature Overview by Maciej Rutkiewicz, Sabina Przygodzka, Katarzyna Gadżała, Karolina Garbino, Katarzyna Brudniak, Antoni Szuścik, Magdalena Czyczerska

“…Identifying sickness includes a physical examination, when we can observe xanthomas, corneal arcus, or xanthomata, and scales that focus on the patient's as well as his family's past. …”
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The Effect of the Glucosinolate Sinigrin on Alterations in Molecular Biomarkers of the Myocardium in Swiss Mice by Nikola Ferara, Vedran Balta, Domagoj Đikić, Dyana Odeh, Ana Mojsović-Ćuić, Lana Feher Turković, Dario Dilber, Anđelo Beletić, Irena Landeka Jurčević, Ivana Šola

“…These results suggest that the hydrolysis products of sinigrin may exert a potentially toxic effect on the myocardial tissue of female mice and possess the capability to modulate transcription factors <i>in vivo</i> in a sex-dependent manner. This observation calls for further investigation into the mechanisms regulating the actions of glucosinolate hydrolysis products, their interactions with sex hormones, and the determination of permissible intake levels associated with both beneficial and adverse outcomes.…”
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PD-L1 monoclonal antibody alleviated MI injury of left ventricular function via modulating CD47/SHP2/SIRPα/SYK/FcγR signalings in tumor associated macrophages by Deyou Kong, Yongzhen Chen, Yajuan Yin, Zhikun Liu, Fang Yang, Xiaohong Li, Dongxing Shen, Jun Zhang

“…Protein expression levels in each group were analyzed by Western blotting, and the macrophages were transplanted into experimental mice for observation. In the in vivo experiments, ultrasound examination showed that PD-L1 mAb improved cardiac function in mice with breast cancer and MI. …”
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The impact of glucagon-like peptide-1 (GLP-1) agonists in the treatment of eating disorders: a systematic review and meta-analysis by Hanieh Radkhah, Shiva Rahimipour Anaraki, Peyvand Parhizkar Roudsari, Razman Arabzadeh Bahri, Diar Zooravar, Sara Asgarian, Reza Hosseini Dolama, Ali Alirezaei, Razieh Khalooeifard

“…Methods A systematic search of PubMed, Scopus, Web of Science, and the Cochrane Library, along with manual searches, identified studies assessing GLP-1 agonists in BED patients up to November 8, 2024. Observational studies and clinical trials meeting inclusion criteria were analyzed. …”
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Muscular Performance and Blood Pressure After Different Pre-Strength Training Strategies in Recreationally Strength-Trained Women: Cross-Over Trial by Estêvão Rios Monteiro, Linda S. Pescatello, Luis Leitão, Marcelo José Colonna de Miranda, Paulo H. Marchetti, Michelle Ribeiro Novaes, Gleisson da Silva Araújo, Victor Gonçalves Corrêa Neto, Jefferson da Silva Novaes

“…No significant reduction was observed in systolic and diastolic BP for any protocol or exercise, although the effect size magnitudes ranged from trivial to large. …”
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The Impact of Multidisciplinary Discussion (MDD) in the Diagnosis and Management of Fibrotic Interstitial Lung Diseases by Ghofran Ageely, Carolina Souza, Kaissa De Boer, Saly Zahra, Marcio Gomes, Nha Voduc

“…Material and Methods. Retrospective observational study in an ILD referral tertiary academic center. …”
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Usefulness of the Hybrid RFR-FFR Approach: Results of a Prospective and Multicenter Analysis of Diagnostic Agreement between RFR and FFR—The RECOPA (REsting Full-Cycle Ratio Compar... by Juan Casanova-Sandoval, Diego Fernández-Rodríguez, Imanol Otaegui, Teresa Gil Jiménez, Marcos Rodríguez-Esteban, Kristian Rivera, Francisco Torres-Saura, Víctor Jiménez Díaz, Raymundo Ocaranza-Sánchez, Vicente Peral Disdier, Guillermo Sánchez-Elvira, Fernando Worner

“…Significant correlation was observed (R2 = 0.81; P<0.001) between the two techniques, with 79% agreement between RFR ≤ 0.89 and FFR ≤ 0.80 (positive predictive value, 68%, and negative predictive value, 80%). …”
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Successful Use of Negative Pressure Wound Therapy for Abdominal Wall Necrosis Caused by a Perforated Ascending Colon Using the ABThera System by Kouki Imaoka, Takuya Yano, Yasuhiro Choda, Ko Oshita, Yuma Tani, Tetsushi Kubota, Michihiro Ishida, Daisuke Satoh, Masanori Yoshimitsu, Kanyu Nakano, Masao Harano, Hiroyoshi Matsukawa, Hitoshi Idani, Shigehiro Shiozaki, Masazumi Okajima

“…The abdominal wall defect was left open, and the ABThera System was used in the management of the OA; this device promoted wound healing. A reduction was observed in the size of the open wound with visible granulation tissue. …”
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Prevalence of nasopharyngeal bacteria during naturally occurring bovine respiratory disease in commercial stocker cattle by Afroza Akter, Hannah Teddleton, Marc Caldwell, Gina Pighetti, Phillip R. Myer, Madison T. Henniger, Liesel Schneider, Elizabeth Shepherd

“…No differences were observed in the alpha diversity matrices based on day or NumTrt (P > 0.05). …”
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Performance of sulfur/steel slag composite matrix in removing nitrate from surface water with low-carbon content by PENG Xianchun, ZHENG Lili, LU Haoran, WANG Zhefeng, ZHU Zheng, LIANG Wenyan

“…A composite matrix of steel slag and elemental sulfur was used for sulfur autotrophic denitrification. SEM was used to observe the surface morphology and microbial adhesion growth on steel slag before and after use. …”
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The impact of oxidative balance on all-cause and cause-specific mortality in US adults and cancer survivors: evidence from NHANES 2001–2018 by Juan Wu, Yingdong Han, Menghui Yao, He Zhao, Zhikai Li, Tiange Xie, Yun Zhang, Xuejun Zeng

“…Among cancer survivors, similar associations were observed with all-cause mortality (HR 0.66). Component analysis revealed consistent protective effects of antioxidant OBS (HR 0.60 for all-cause mortality), while higher pro-oxidant OBS showed varying associations across mortality causes. …”
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Extremely early initiation of vasopressors might not decrease short-term mortality for adults with septic shock: a systematic review and meta-analysis by Cheng-Hsin Ma, Jack Healy, Ebrima Kinteh, Cheng-Chin Ma, Ching-Fang Tiffany Tzeng, Eric H. Chou, Chin-Chieh Wu, Shih-Chieh Shao, Kuan-Fu Chen

“…No significant difference in short-term mortality was observed between early and late administration in the combined analysis of 3,757 patients from two RCTs and three quasi-experimental studies (OR: 0.66, 95% CI: [0.36, 1.19], I²: 82%). …”
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Instrumentation Removal following Minimally Invasive Posterior Percutaneous Pedicle Screw-Rod Stabilization (PercStab) of Thoracolumbar Fractures Is Not Always Required by Neil Manson, Dana El-Mughayyar, Erin Bigney, Eden Richardson, Edward Abraham

“…Methods. A prospective observational study of 32 consecutive patients receiving PercStab without direct decompression or fusion. …”
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