lnc-MRGPRF-6:1 Promotes ox-LDL-Induced Macrophage Ferroptosis via Suppressing GPX4 by Zhihuan You, Xiaotian Ye, Meihua Jiang, Ning Gu, Caihong Liang

“…Then, ferroptosis-related biomarkers and mitochondrial morphology were detected and observed in ox-LDL-treated macrophages. Subsequently, we constructed lnc-MRGPRF-6:1 knockdown and overexpression of THP-1-derived macrophages and investigated the role of lnc-MRGPRF-6:1 in ox-LDL-induced ferroptosis. …”
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Thyroid Function in Chronically Transfused Children with Beta Thalassemia Major: A Cross-Sectional Hospital Based Study by Suraj Haridas Upadya, M. S. Rukmini, Sowmya Sundararajan, B. Shantharam Baliga, Nutan Kamath

“…Subclinical hypothyroidism was the thyroid dysfunction observed in our study. Regular blood transfusions with adequate chelation may decrease incidence of thyroid dysfunction.…”
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Transcriptomic analysis of Medicago truncatula calli with MtWOX9-1 overexpression by V. E. Tvorogova, E. Y. Krasnoperova, A. A. Kudriashov, K. A. Kuznetsova, E. A. Potsenkovskaya, Y. A. Fedorova, L. A. Lutova

“…This process rarely can be observed in nature, but for many plant species, in vitro protocols are developed, which allow to obtain somatic embryos formation directly from tissues of plant explant or from the embryogenic callus. …”
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A surge in female condom distribution during the COVID-19 pandemic in Gauteng province, South Africa by Cyril Bernsah Fonka, Nicola Christofides

“…The highest female condom distribution during the pandemic was observed in the Ekurhuleni Metropolitan (150.0%), followed by the Sedibeng (92.8%) and the Johannesburg Metropolitan (67.9%) districts respectively. …”
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Numerical Investigation of Ultra-Wide Low-Frequency Wave Attenuation Using Seismic Metamaterials with Auxetic Slender Strips by Haosheng Liu, Hongbo Zhang

“…Interestingly, significant vibration attenuation, approaching 70 dB, was observed below the first complete band gap (approximately 0.22–1.17 Hz), even without the use of concrete. …”
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Effect of a Novel Training Program in Patients With Chronic Shoulder Pain Based on Implicit Motor Learning: Pilot and Feasibility Study. by Annelies Maenhout, Wieger Heijenk, Peter Glashouwer, Lore Quatacker, Luna Praet, Dorien Borms

“…Statistically significant improvements were observed for SPADI (p\<0.001), NRS at rest (p=0.033), at night (p=0.29), PSFS (p\<0.001) and PASS (p\<0.001) after only six weeks training…”
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Assessing the Role of Incubation Temperature as a Barrier to Successful Establishment of Coho Salmon (Oncorhynchus kisutch) in a Rapidly Warming Arctic by Elizabeth D. Lindley, Karen M. Dunmall, Peter A. H. Westley

“…Spawning temperatures were 6°C at the warmest (AUG1) and 1.25°C at the coldest (OCT1). We observed low survival rates in SEPT1 (41%) and OCT1 (34%) and near complete mortality in the other treatments. …”
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PGTransNet: a physics-guided transformer network for 3D ocean temperature and salinity predicting in tropical Pacific by Song Wu, Senliang Bao, Wei Dong, Senzhang Wang, Xiaojiang Zhang, Chengcheng Shao, Junxing Zhu, Xiaoyong Li

“…Our proposal demonstrates higher prediction accuracy with fast convergence, and the metrics and visualizations show that our model is insensitive to hyperparameter tuning, ensuring better generalization and adherence to physical consistency. Moreover, as observed from the spatial distribution of the anomaly correlation coefficient, the model exhibits higher forecasting accuracy for coastal and marginal sea regions.…”
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Comparative study of PCR test kits for ASFV DNA detection by M. S. Krasnikova, S. P. Yatsentyuk, M. B. Bryusova, A. D. Kozlova, М. А. Gergel

“…It was noted that some manufacturers make serious errors in the instructions, which can significantly affect the interpretation of test results. It was also observed that there is insufficient control of the manufacturing process, which results in the production of faulty kits, as well as kits with poor-quality components and errors in the labeling. …”
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Clinical Efficacy Between Intravenous Paracetamol and Intravenous Fentanyl for Propofol Deep Sedation in Colonoscopy: A Randomized Controlled Trial by Thiparporn T, Supan W, Amornyotin S

“…No serious complications were observed in either group.Conclusion: Intravenous paracetamol with propofol deep sedation in adult patients is non-inferior to intravenous fentanyl for successful colonoscopy completion. …”
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Serotyping and antimicrobial resistance of Actinobacillus pleuropneumoniae isolates from fattening pigs in Poland from 2019 to 2024 by Przyborowska Paulina, Tobolski Dawid

“…High resistance rates were observed for tylosin (55.5%), gentamicin (36.1%), doxycycline (32.8%), and sulfamethoxazole/trimethoprim (26.1%). …”
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Machine learning-based prognostic model for patients with anaplastic thyroid carcinoma by Yihan Sun, Da Lin, Xiangyang Deng, Yinlong Zhang

“…And we further ranked the time-dependent features according to their permutation importance and observed that surgery, radiotherapy, and chemotherapy were the most influential predictors initially. …”
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An 8-week physical exercise intervention for e'athletes improves physical performance rather than short-term esports performance parameters - a randomized controlled trial by Felix Wachholz, Nicole Gamper, Martin Schnitzer

“…The weekly questionnaire indicated a significant improvement in participants' well-being.DiscussionWhile training improved physical variables, no effects were observed in suggested short-term performance. However, gaming hours and experience during the intervention positively influenced performance. …”
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Infection Prevalence and Antibiotic Resistance Levels in Ureaplasma urealyticum and Mycoplasma hominis in Gynecological Outpatients of a Tertiary Hospital in China from 2015 to 201... by Wei Zhang, Lijuan Li, Xuelian Zhang, Hongshu Fang, Huajian Chen, Changxian Rong

“…Increases in the prevalence of infection and antibiotic resistance in U. urealyticum and M. hominis were observed from 2015 to 2018, clearly confirming the necessity to monitor the standardized administration of antibiotics.…”
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Altered Brain Activity and Effective Connectivity within the Nonsensory Cortex during Stimulation of a Latent Myofascial Trigger Point by Xinglou Li, Meiling Luo, Yan Gong, Ning Xu, Congcong Huo, Hui Xie, Shouwei Yue, Zengyong Li, Yonghui Wang

“…An increasing trend of WA and a decreasing trend of EC values were observed in the PFC. The interregional mCD was primarily shifted from a unidirectional to bidirectional connection, especially from PFC to MC or OL, when responding to manual stimulation during the MTrP state compared with resting state and NMTrP state in the intervals III, IV, and V. …”
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‘Bulun in Winter Is So Sad’: A. Bogolepov about Everyday Life in Polar Yakutia, 1913–1916 by Lilia I. Vinokurova, Alexander A. Suleymanov, Svyatoslav I. Fedorov

“…The narrative was written before the revolutionary events of 1917 and is of certain interest since it lacks any political bias, being characterized by restrained neutrality and sufficient depth of observations over everyday realias of the small northern settlement. …”
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Evaluation of the impact of antibody fragments on aggregation of intact molecules via size exclusion chromatography coupled with native mass spectrometry by Jing Xu, John E. Coughlin, Malgorzata Szyjka, Serene Jabary, Sonal Saluja, Zoran Sosic, Yunqiu Chen, Chong-Feng Xu

“…In this study, we focused on understanding mAb stability in the presence of its monovalent fragment, formed through hinge cleavage and loss of one Fab unit (referred to as “Fab/c”), a commonly observed impurity during manufacturing and stability. …”
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Antibacterial and antibiofilm activities of kaffir lime essential oils and their active constituents against Staphylococcus aureus focusing on sortase A by Chayapol Pontanayodsakorn, Chatchakorn Eurtivong, Pimsumon Jiamboonsri

“…This is followed by morphological studies to observe change in biofilm formations using light and scanning electron microscopy (SEM). …”
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Biodiversity reporting: Comparing listed entities in the United Kingdom and South Africa by Dino Da Mata, Timothy Lai, Dusan Ecim, Warren Maroun, Dannielle Cerbone

“…However, UK companies tend to provide more quantitative and valuation-based disclosures because of their advanced management information systems, professional standards network support and access to financial resources. In general, it is observed that biodiversity reporting is still in its nascent stage in both jurisdictions and offers limited insight into the understanding of biodiversity by organisations and their ability to incorporate direct and indirect impacts into their business models, risk assessment and strategy implementation. …”
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Synthesized 18-Lead Electrocardiogram in Diagnosing Posterior Stemi-Equivalent Acute Coronary Syndrome in Patients with NSTEMI by Tomoki Horie, Rikuta Hamaya, Tomoyo Sugiyama, Hidenori Hirano, Masahiro Hoshino, Yoshihisa Kanaji, Tetsumin Lee, Taishi Yonetsu, Tetsuo Sasano, Tsunekazu Kakuta

“…LCx-culprit NSTEMI occurred in 58 (26.5%) patients and 15 (6.8%) were LCx STEMI-equivalent. SV7-9 STE was observed in 16 patients (7.9%). SV7-9 STE was the sole significant predictor of LCx STEMI-equivalent ACS with an odds ratio of 19.0 (95% CI: 5.6–63.9, p<0.001), area under the curve of 0.71 (95% CI: 0.58–0.84), sensitivity of 46.7%, and specificity of 95.6%. …”
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