Revealing intra- and inter-container fruit quality heterogeneity within overseas refrigerated container shipments using a physics-based digital twin by Celine Verreydt, Tarl Berry, Leo Lukasse, Deniz Turan, Paul Cronje, Thijs Defraeye

“…In contrast to the limited intra-container quality heterogeneity, significant inter-container differences were observed. This indicates the added value of monitoring each shipment. …”
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Genome-wide CRISPR-based screen identifies E2F transcription factor 1 as a regulator and therapeutic target of aristolochic acid-induced nephrotoxicity by Ziqi Liu, Huan Gao, Guoliang Li, Yongjiang Yu, Mengxing Cui, Honghao Peng, Xinchao Guan, Xue Zhang, Zhihan Zhang, Xiaoyu Shen, Shen Chen, Daochuan Li, Liping Chen, Yongmei Xiao, Wen Chen, Lili Liu, Qing Wang

“…Among the altered sgRNAs, a significant enrichment of those targeting the E2F transcription factor 1 (E2F1) gene was observed in surviving HK-2 cells in the AAI-treated group. …”
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Problematic internet use and its relationship with eating disorders by Claudia Ruiz-Centeno, Raquel Cueto-Galán, Raquel Cueto-Galán, Raquel Cueto-Galán, Jose Miguel Pena-Andreu, Andrés Fontalba-Navas, Andrés Fontalba-Navas, Andrés Fontalba-Navas

“…Additionally, a widespread positive sentiment towards low weight and thinness was observed, while negative sentiments were associated with eating, gaining weight, etc. …”
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Effects of Soil-Transmitted Helminths and Intestinal Protozoan Infections on Haemoglobin Levels among School-Aged Children in Belo and Bui, North West Cameroon: A Cross-Sectional S... by Frederick Nchang Cho, Humphrey Ngala Ngala, Ranibell Tung Bongazi, Rogers Sanga Kinsam, Beltha Tahnteng Tata, Desmond Aji, Paulette Ngum Fru, Patrick Kofon Jokwi

“…Soil-transmitted helminths, intestinal protozoan infections, and anaemia are prevalent in the study area. Anaemia was observed to be associated with STH, intestinal protozoa, and the communities under study. …”
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A growing degree day model determines the effect of temperature stress on diverse chickpea genotypes by Cara Jeffrey, Cara Jeffrey, Cara Jeffrey, Laura Ziems, Laura Ziems, Brent Kaiser, Brent Kaiser, Richard Trethowan, Richard Trethowan

“…Using a multi-environment trial, traits such as time to flowering, and seed size were observed in 148 chickpea cultivars across two sowing times in two different Australian locations (Narrabri in New South Wales, and Kununurra in Western Australia). …”
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Rational design of a triple-type HPV53/56/66 vaccine with one preferable base particle incorporating two identified immunodominant sites by Ciying Qian, Jie Chen, Yurou Yang, Yihan Lu, Tianyu Ren, Yanan Jiang, Yang Huang, Xin Chi, Shuyue Zhang, Chengzong Zhang, Kewei Li, Jingjia Shen, Sibo Zhang, Daning Wang, Lizhi Zhou, Tingting Li, Qingbing Zheng, Hai Yu, Ying Gu, Ningshao Xia, Shaowei Li

“…By incorporating two identified immunodominant sites into the preferable base particle, the study constructed a triple-type chimera H66-56HI-53FG, which could efficiently self-assemble into VLPs in vitro that closely resembled the wild-type HPV66 VLP and, induced balanced triple-type neutralization titers (~ 3 log unites), as contrast to none observable HPV53 neutralization titer and lower HPV56 titer elicited by the immunization of the wild-type HPV66 alone. …”
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Anticancer Potential of Green Synthesized Silver Nanoparticles Using Extract of Nepeta deflersiana against Human Cervical Cancer Cells (HeLA) by Ebtesam S. Al-Sheddi, Nida N. Farshori, Mai M. Al-Oqail, Shaza M. Al-Massarani, Quaiser Saquib, Rizwan Wahab, Javed Musarrat, Abdulaziz A. Al-Khedhairy, Maqsood A. Siddiqui

“…The cytotoxic response observed was in a concentration-dependent manner. Furthermore, the results also showed a significant increase in ROS and lipid peroxidation (LPO), along with a decrease in MMP and glutathione (GSH) levels. …”
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Minimally Invasive Fetoscopic Resection of Life-Threatening Amniotic Band Constrictions in a Human Fetus at 22 + 2 Weeks of Gestation Complicated by Subtotal Chorioamniotic Separat... by Nadja Riehle, Oliver Nowak, Leila Messroghli, Samantha Wakerlin, Thomas Schaible, Thomas Kohl

“…No surgical complications were observed. Despite preterm delivery at 25 + 4 weeks of gestation, the postnatal experience for the infant was favorable and uncomplicated as it furthermore benefitted from neonatal intensive care. …”
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Organic minerals restore the acid-base and electrolyte balance in broiler chicks with nutritionally induced metabolic acidosis by L.M. Macalintal, A.J. Pescatore, T. Ao, M.J. Ford, K.A. Dawson

“…Significant interactions for vitamin levels and mineral form were observed for bicarbonate, base excess, total carbon dioxide, ionised calcium and haematocrit levels. …”
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Development of Genomic SSR Markers for Assessing Genetic Diversity in Korean Native <i>Fallopia multiflora</i> by Raveendar Sebastin, Ki Hyun Kim, Hye Ran Shin, Jin-Tae Jeong, Ju-Kyung Yu, Yoon-Sup So, Jong-Wook Chung

“…The major allele frequency (MAF) spanned from 0.20 to 0.90, the observed heterozygosity (HO) ranged from 0 to 0.80, and the polymorphic information content (PIC) varied between 0.16 and 0.86. …”
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Long-Term Results of the Etiotropic Therapy of Subcompensed Liver Cirrhosis in the Outcome of Chronic Hepatitis C by P. O. Bogomolov, A. O. Bueverov, V. E. Bakirova, E. O. Lyusina, E. A. Fedosyina, S. V. Koblov, O. V. Sumtsova

“…At that time, 27 patients were available for observation. The assessment of liver function compensation using the Child-Pugh score showed improvement in 25 (93 %) patients. …”
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Decoding the trajectory of antibiotic resistance genes in saline and alkaline soils: Insights from different fertilization regimes by Dandan Zhang, Jie Li, Guilong Zhang, Yan Xu

“…Beside the effect of direct input of organic fertilizer at the beginning, it was important to note that, ARGs abundance during planting showed significant correlations with pH and electric conductivity. We observed that changes in microbial survival strategies under different salinity and alkalinity conditions further affected ARG hosts abundance. …”
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Integrated analysis of chromatin and transcriptomic profiling of the striatum after cerebral hypoperfusion in mice by Shijia Le, Fengyiyang Xu, Zhi Luo, Weihao Shi, Shuangshuang Lu, Zengyu Zhang, Zimin Guo, Wenshi Xu, Mingqi Yang, Tianyi Li, Xu Li, Kun Liang, Lei Zhu

“…The integration of these datasets allowed us to correlate chromatin accessibility with transcriptional activity and to identify key transcription factors driving the observed gene expression changes. Results Analysis of striatum-specific transcriptome revealed significant upregulation of immune response genes, particularly type II interferon signaling, and downregulation of neural activation pathways. …”
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The use of urinary kidney injury molecule-1 and neutrophil gelatinase-associated lipocalin for diagnosis of hepato-renal syndrome in advanced cirrhotic patients by Mohamed Adel Abd Elaziz, Asmaa Mustafa Gouda Elewa, Dina Zaki Mohamed Zaki Abdel Hamid, Nohier Essam Soliman Ahmed Hassan, Éva Csongrádi, Emad Hamdy Hamouda Mohammed, Mohammed Abdel Gawad

“…However, the interpretation of serum Cr level can be confounded by malnutrition and reduced muscle mass often observed in patients with severe liver disease. Here, we present a cross-sectional study to explore the sensitivity and specificity of other markers as urinary KIM-1 and NGAL for cases of HRS.Methods Cross-sectional study was conducted on 88 patients who were admitted to Alexandria main university hospital. …”
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Impact of Long COVID on Lung Function in Children by Zeynep Reyhan ONAY, Sinem CAN OKSAY, Deniz MAVI TORTOP, Gulay BILGIN, Yetkin AYHAN, Ferit DURANKUS, Saniye GIRIT

“…Within a median duration of 85 days (minimum-maximum: 35-194) following COVID-19 infection, a restrictive pattern was observed to be more common in the study group (p=0.021). …”
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Bilateral lower limb symmetry during sit-to-stand and stand-to-sit tasks in stroke patients with hemiplegia by Meijin Hou, Meijin Hou, Jian He, Dongwei Liu, Chenyi Guo, Ye Ma, Xiaobo Luo

“…In the stroke group, notable bilateral asymmetry (SI &gt; 10%) was observed in the ankle joint angle (P &lt; 0.05) during both tasks. …”
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Exposure to major coronary heart disease events reduces lung cancer risk: a mendelian randomization study based on a European population by Dongming He, Hongting Lu, Xinhuai Ou, Tiaozhan Zheng, Zhiwen Zheng, Zhanyu Xu, Xiaohong Duan, Shikang Li

“…However, this protective effect was not observed for other types of lung cancer. Furthermore, substituting FinnGen's MCHDE with that from IEU OpenGWAS did not yield similar protective effects across various lung cancer subtypes. …”
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Optimizing lipopeptide bioactivity: The impact of non-ionic surfactant dressing by Ágnes Ábrahám, Gergő Gyulai, Judith Mihály, Andrea Horváth, Orsolya Dobay, Zoltán Varga, Éva Kiss, Kata Horváti

“…Similar homogenous micelle formation was observed after freeze-drying and reconstitution with water. …”
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A cross-sectional study to determine prevalence of neonatal dermatoses in a tertiary health care centre of Andhra Pradesh, South India by Deepti Vemu, Shalini Eslavat, Shankar Kunti, Prasad Naik NM, Ritu Gujarati Vishwanath, Sruthi Kamatham

“…Miniature pubertal signs were commonly observed in newborns of multiparous women (p <0.05) amongst which, genital hyper pigmentation (p = 0.03) was most common (p < 0.01). …”
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Can growth in captivity alter the calcaneal microanatomy of a wild ungulate? by Cottereau, Romain, Ortiz, Katia, Locatelli, Yann, Houssaye, Alexandra, Cucchi, Thomas

“…Furthermore, changes in the internal structure of the calcaneus between mobility patterns are observed but their intensity is not directly associated with the degree of mobility restriction and only weakly impacted by the size or weight of the individuals. …”
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