Hippocampus-sparing volume-modulated arc therapy in patients with World Health Organization grade II glioma: a feasibility study by Renxian Xie, Renxian Xie, Hongxin Huang, Hongxin Huang, Qingxin Cai, Jiayang Lu, Tong Chen, Tong Chen, Keyan Xie, Jianzhou Chen, Chuangzhen Chen

“…The dose volume histogram (DVH), homogeneity index (HI), conformity index (CI), and irradiated dose of the hippocampus and other organs at risk (OARs) were analyzed.ResultsNo significant differences were observed in HI and CI between the two plans. Regarding the protection of OARs, HS VMAT plans were equally capable and even lowered the radiation dosages to the brainstem (35.56 vs. 41.74 Gy, p = 0.017) and spinal cord (1.34 vs. 1.43 Gy, p = 0.006). …”
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Plasma Concentrations of Benzylpenicillin and Cloxacillin in Infective Endocarditis—With Special Reference to Delayed Hypersensitivity Reactions by Malin Hägglund, Ulrika Snygg-Martin, Lars Olaison, Michael Stofkoper, Bert Ove Larsson, Magnus Brink

“…There was no relation between high plasma concentration and the prevalence of DHR; conversely, we observed a tendency of low plasma concentrations in these patients. …”
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Body composition changes and clinical outcomes in pediatric cystic fibrosis during 24 months of lumacaftor ivacaftor therapy based on real-world data by Marcell Imrei, Adrienn F. Kéri, Éva Gács, Ildikó Gönczi, Melinda Meláth, Éva Kosaras, Botond Demeter, Csaba Péterfia, Klára Vass, Gyöngyi Székely, Klementina Ocskay, Andrea Párniczky

“…We aimed to investigate the effects of 24-month lumacaftor/ivacaftor (LUM/IVA) therapy in pediatric CF patients (pwCF). This observational study included pwCF homozygous for F508del mutation treated between 2021 and 2023. …”
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Development of New Biosorbent Based on Crosslinked Chitosan Beads with High Brilliant Blue FCF Removal Efficiency by Fatiha Lahgui, Beatriz Delgado Cano, Antonio Avalos Ramirez, Michèle Heitz, Hafida Hadjar, Samia Kaddour

“…A maximum biosorption capacity of 600 mg/g corresponding to 99% removal efficiency was observed at pH 3.0, a biosorbent dose of 0.5 g/L, an initial dye concentration of 300 mg/L, a contact time of 10 h, and a temperature of 323 K. …”
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Endoscopic Submucosal Single- or Multi-tunnel Dissection for Near-Circumferential and Circumferential Superficial Esophageal Neoplastic Lesions by Lin-Lin Zhu, Jun-Chao Wu, Yi-Ping Wang, Du He, Wen-Yan Zhang, Tao Gan, Jin-Lin Yang

“…Esophageal stricture was observed in 54 patients and was relieved by placement of a retrievable metal stent or by endoscopic water balloon dilation. …”
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Cytokine Kinetics in Febrile Neutropenic Children: Insights on the Usefulness as Sepsis Biomarkers, Influence of Filgrastim, and Behavior of the IL-23/IL-17 Pathway by Orlei Ribeiro de Araujo, Reinaldo Salomão, Milena Karina Coló Brunialti, Dafne Cardoso Bourguignon da Silva, Andreza Almeida Senerchia, Fabianne Altruda de Moraes Costa Carlesse, Antonio Sergio Petrilli

“…Filgrastim upregulates expression of these markers, and we observed deficiency in the IL-23-IL-17 axis accompanying sepsis.…”
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Spatial scales matter in designing buffer zones for coastal protected areas along the East Asian-Australasian Flyway by Roger H. Lee, Ivan H.Y. Kwong, Tom C.H. Li, Paulina P.Y. Wong, Yik-Hei Sung, Yat-Tung Yu

“…Waterbird occurrences were influenced by the spatial extent of suitable habitats, with variations observed across different guilds and seasons. In the study area, maintaining at least 40 % open water within an 800-meter radius of key habitats better supports diverse waterbird guilds and should inform the design of waterbird-friendly landscape profiles for protected areas and their buffer zones. …”
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Modelling the seasonal dynamics of Aedes albopictus populations using a spatio-temporal stacked machine learning model by Daniele Da Re, Giovanni Marini, Carmelo Bonannella, Fabrizio Laurini, Mattia Manica, Nikoleta Anicic, Alessandro Albieri, Paola Angelini, Daniele Arnoldi, Federica Bertola, Beniamino Caputo, Claudio De Liberato, Alessandra della Torre, Eleonora Flacio, Alessandra Franceschini, Francesco Gradoni, Përparim Kadriaj, Valeria Lencioni, Irene Del Lesto, Francesco La Russa, Riccardo Paolo Lia, Fabrizio Montarsi, Domenico Otranto, Gregory L’Ambert, Annapaola Rizzoli, Pasquale Rombolà, Federico Romiti, Gionata Stancher, Alessandra Torina, Enkelejda Velo, Chiara Virgillito, Fabiana Zandonai, Roberto Rosà

“…In our study, we utilized a recently published dataset documenting egg abundance observations of Aedes albopictus collected using ovitraps. and a set of environmental predictors to forecast the weekly median number of mosquito eggs using a stacked machine learning model. …”
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Characteristics of GaN/InGaN Double-Heterostructure Photovoltaic Cells by Ming-Hsien Wu, Sheng-Po Chang, Shoou-Jinn Chang, Ray-Hua Horng, Wen-Yih Liao, Ray-Ming Lin

“…The decrease of Voc and FF was observed as In composition increasing from 10% to 14%. …”
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Association between magnesium depletion score and prevalence of hyperuricemia in American adults: a study based on NHANES 2007-2018 by Yongchun Xiao, Yong Mou, Yong Mou, Ping Wu, Ke Wang, Tianjun Chen, Zhiwan Chen, Hongsheng Lin, Hua Yang, Zhisheng Ji

“…Subgroup analysis indicated a positive association between MDS and HUA, with significant interactions observed for sex and body mass index. Sensitivity and additional analyses reinforced the robustness of these findings.ConclusionAmong U.S. adults, higher MDS were significantly associated with an increased prevalence of HUA, suggesting that interventions targeting magnesium deficiency could be beneficial in reducing HUA prevalence within this population. …”
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High-Flow Nasal Cannula: A Promising Oxygen Therapy for Patients with Severe Bronchial Asthma Complicated with Respiratory Failure by Wanru Geng, Wuliji Batu, Shuhong You, Zhaohui Tong, Hangyong He

“…In patients with bronchial asthma, effectively increased PO2 and reduced PCO2 were observed after treatment in both groups. However, HFNC was more efficient than COT in elevating PO2 in patients with severe bronchial asthma complicated with respiratory failure, while no statistically significant difference in PCO2 reduction was found between the two groups. …”
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Proinflammatory Cytokine IL-6 and JAK-STAT Signaling Pathway in Myeloproliferative Neoplasms by Vladan P. Čokić, Olivera Mitrović-Ajtić, Bojana B. Beleslin-Čokić, Dragana Marković, Marijana Buač, Miloš Diklić, Nada Kraguljac-Kurtović, Svetozar Damjanović, Pavle Milenković, Mirjana Gotić, Puri K. Raj

“…Regarding laboratory data, leukocytosis has been observed in polycythemia vera (PV) and JAK2V617F mutation positive versus negative primary myelofibrosis (PMF) patients. …”
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Does candidate race influence simulated patient ratings in standardised assessments of clinical practice? A single-blinded randomised study in UK medical schools by Celia Brown, Amir H Sam, Rachel Westacott, Mark Gurnell, Sarah Khavandi, Malcolm Reed, Ann Sebastian, Kerry Badger

“…Therefore, each simulated patient assessor observed one white and one non-white candidate at each grade and scored communication and professionalism domains.Main outcome measure The median and interquartile range of the difference between total scores for the white and non-white candidates were compared at all three performance grades.Results The black fail candidate scored statistically significantly lower than their white fail counterpart. …”
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Essential and risk elements in horses affect haematology, serum biochemistry and oxidative status parameters by Marko Halo, Róbert Kirchner, Filip Tirpák, Tomáš Slanina, Katarína Tokárová, Anton Kováčik, Michal Miškeje, Agnieszka Greń, Grzegorz Formicki, Marko Halo, Roberto Madeddu, Peter Massányi

“…Finally, this investigation based on correlation analyses identified essential and risk elements in horse blood serum and significant negative correlation between Cd and GRA, HGB and HCT was observed in The National Stud Farm Topoľčianky and a positive correlation was recorded between Zn and total proteins in the Experimental Centre at Institute of Animal Husbandry, SUA Nitra. …”
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Edaravone dexborneol alleviates pericyte-mediated fibrosis depositing extracellular matrix through TGF-β1/IL-11 in cerebral small vessel disease by Qingrui Duan, Zhiyang Liu, Yuxuan Xing, Haifeng Huang, Lin Zhu, Jiaxuan Liu, Peikun He, Guixian Ma, Yuhu Zhang, Kun Nie, Yuyuan Gao, Lijuan Wang

“…RNA sequencing of OGD in pericytes was performed to identify a key signaling pathway. Results We observed that both medium and high concentrations of EDB could ameliorate CCH-induced cognitive impairment and emotional disorders. …”
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Malignancy Risk and Related Factors of Atypia of Undetermined Significance/Follicular Lesion of Undetermined Significance in Thyroid Fine Needle Aspiration by So-hyeon Hong, Hyejin Lee, Min-Sun Cho, Jee Eun Lee, Yeon-Ah Sung, Young Sun Hong

“…Among histologically confirmed nodules, the US features were more unfavorable in malignant nodules, and hypo- or anechogenicity was associated with a higher risk of malignancy after adjusting for age, size, and other US features (P<0.01). In conclusion, we observed that malignant nodules tended to show unfavorable US features, especially hypo- or anechogenicity. …”
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Flux pinning in superconducting multilayer 2H-NbSe2 nano-step junction by Minseong Kwon, Mingi Kim, Yoonji Gong, Heeyeon Lee, Young Duck Kim

“…The upper critical field was estimated to be 4.5 T and the Ginzburg–Landau coherence length 8.6 nm. Additionally, we observed phase transitions induced by vortex viscous dynamics in the 2H-NbSe _2 step junction. …”
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Comparison of intraoperative neurophysiological monitoring between propofol and remimazolam during total intravenous anesthesia in the cervical spine surgery: a prospective, double... by Myoung Hwa Kim, Jinyoung Park, Yoon Ghil Park, Yong Eun Cho, Dawoon Kim, Dong Jun Lee, Kyu Wan Kwak, Jongyun Lee, Dong Woo Han

“…Conclusions TIVA with remimazolam and remifentanil for cervical spine surgery yielded stable IONM, comparable to those observed with conventional TIVA with propofol and remifentanil. …”
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NMDA Reduces Tau Phosphorylation in Rat Hippocampal Slices by Targeting NR2A Receptors, GSK3β, and PKC Activities by Audrée De Montigny, Ismaël Elhiri, Julie Allyson, Michel Cyr, Guy Massicotte

“…Compared with nontreated slices, we observed that NMDA receptor activation was reflected in high Ser9 and low Tyr216 phosphorylation of glycogen synthase kinase-3 beta (GSK3β), suggesting that NMDA receptor activation might diminish Tau phosphorylation via a pathway involving GSK3β inhibition. …”
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Interpreting Variants of Uncertain Significance in PCD: Abnormal Splicing Caused by a Missense Variant of DNAAF3 by Haixia Zheng, Chongsheng Cheng, Miao He, Wangji Zhou, Yixuan Li, Jinrong Dai, Ting Zhang, Kai‐Feng Xu, Xue Zhang, Xinlun Tian, Yaping Liu

“…The absence of outer dynein arms and inner dynein arms was also observed. Conclusions Our study identified two compound heterozygous variants of DNAAF3, a pathogenic gene for PCD, and proved that a novel missense variant c.1364G>A affects splicing. …”
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