Showing 24,301 - 24,320 results of 30,477 for search '"The Observer"', query time: 0.13s Refine Results
  1. 24301

    IL-31 and IL-8 in Cutaneous T-Cell Lymphoma: Looking for Their Role in Itch by Maria Abreu, Marta Miranda, Mafalda Castro, Iolanda Fernandes, Renata Cabral, Ana Helena Santos, Sónia Fonseca, João Rodrigues, Magdalena Leander, Catarina Lau, Inês Freitas, Susana Coimbra, Alice Santos-Silva, Margarida Lima

    Published 2021-01-01
    “…Increased serum IL-8 observed in some patients may be related to concomitant infections, and its role in exacerbating itch by recruiting neutrophils and promoting the release of neutrophil proteases deserves further investigation.…”
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  2. 24302

    Genome-Wide Analysis, Characterization, and Expression Profile of the Basic Leucine Zipper Transcription Factor Family in Pineapple by Yanhui Liu, Mengnan Chai, Man Zhang, Qing He, Zhenxia Su, S. V. G. N. Priyadarshani, Liping Liu, Guanxi Dong, Yuan Qin

    Published 2020-01-01
    “…A significant response was observed for AcobZIP24 against all kinds of abiotic stresses at 24 and 48 h in pineapple root tissues. …”
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  3. 24303

    Pleiotropic effects of mutant huntingtin on retinopathy in two mouse models of Huntington's disease by Hui Xu, Anakha Ajayan, Ralf Langen, Jeannie Chen

    Published 2025-02-01
    “…The retina is part of the central nervous system (CNS), and visual deficits and structural abnormalities in the retina of HD patients have been observed. Defects in retinal structure and function are also present in the R6/2 and R6/1 HD transgenic mouse models that contain a gene fragment to express mHTTex1. …”
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  4. 24304

    Exploring the Therapeutic Role of Physical Activity in Psychotic Disorders: Cognitive, Somatic, and Mental Health Impacts by Klaudia Fikas, Kamil Chwaliszewski, Dorota Waz, Michał Mazur, Jakub Szarłowicz, Zofia Goliszek, Karolina Łucja Sobek, Wiktoria Tabin-Barczak, Aldona Sokołowska, Sebastian Samuła

    Published 2025-01-01
    “…Studies eligible for inclusion were observational research, clinical trials, and meta-analyses that examined the role of physical activity in alleviating somatic symptoms, reducing fatigue, and improving overall well-being in individuals with psychotic disorders. …”
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  5. 24305

    Surgical Treatment Intensity at the End of Life in Patients With Cancer: A Systematic Review by Samuel Lawday, BMBS, MByRes, Benjamin E. Zucker, MA, MBBS, MRCS, Shona Gardner, MBChB, MRCS, James Robb, MBChB, MA, Lorna Leandro, MA, BM, BCh, William Hollingworth, PhD, Jane Blazeby, MBChB, MD, Angus G.K. McNair, PhD, FRCS, Charlotte Chamberlain, PhD, MRCP

    Published 2024-12-01
    “…This PROSPERO registered systematic review used PRIMSA guidelines to search electronic databases for observational studies detailing surgical intensity at the EoL in adult cancer patients. …”
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  6. 24306

    Ferroptosis triggers mitochondrial fragmentation via Drp1 activation by Lohans Pedrera, Laura Prieto Clemente, Alina Dahlhaus, Sara Lotfipour Nasudivar, Sofya Tishina, Daniel Olmo González, Jenny Stroh, Fatma Isil Yapici, Randhwaj Pratap Singh, Nils Grotehans, Thomas Langer, Ana J. García-Sáez, Silvia von Karstedt

    Published 2025-01-01
    “…During ferroptosis, a recently identified type of regulated necrosis driven by excessive lipid peroxidation, mitochondrial fragmentation has been observed. Yet, how this is regulated and whether it is involved in ferroptotic cell death has remained unexplored. …”
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  7. 24307

    Boosting disassembly of π–π stacked supramolecular nanodrugs under tumor microenvironment by introducing stimuli‐responsive drug‐mates by Wenzhe Xu, Ruixu Yang, Yingke Xue, Yang Chen, Shuwei Liu, Songling Zhang, Yonggang Wang, Yi Liu, Hao Zhang

    Published 2025-01-01
    “…Both the experimental observation and computational simulation indicate that the disassembly of SNDs under simulated TME highly depends on the disassembly activation energy (ΔEdis) of neighboring π–π stacked molecules. …”
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  8. 24308
  9. 24309
  10. 24310

    Promoting ER stress in a plasmacytoid dendritic cell line drives fibroblast activation by Beatriz H. Ferreira, Inês S. Silva, Andreia Mendes, Fátima Leite-Pinheiro, Adrienne W. Paton, James C. Paton, Iola F. Duarte, Philippe Pierre, Catarina R. Almeida

    Published 2025-02-01
    “…This effect required expression of the ER stress signaling sensor protein kinase R-like ER kinase (PERK) in pDCs and was observed only upon direct contact between both cell types. …”
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  11. 24311

    Thromboelastography in Patients with Inflammatory Bowel Disease by Yonghua Shen, Liangliang Shi, Juanjuan Zhang, Hao Zhu, Yuling Yao, Zhenqing Liu, Xiaoping Zou, Xiaoqi Zhang

    Published 2020-01-01
    “…No statistical differences were observed in LY30 among patients with active phase, patients in remission, and the healthy individuals. …”
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  12. 24312

    Correlation between daily physical activity and intestinal microbiota in perimenopausal women by Yanqiu Zheng, Junyu Ke, JinBin Song, Xuyu Li, Rongman Kuang, Haiyan Wang, Shuang Li, Yanwu Li

    Published 2025-05-01
    “…Furthermore, a positive correlation was observed between Chloroflexi or Sphingomonas and physical activity (kcals, METs, and MVPA), while a negative correlation was found between Intestinimonas and physical activity (METs: p < 0.01, and MVPA: p < 0.05). …”
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  13. 24313

    Race or Resource? BMI, Race, and Other Social Factors as Risk Factors for Interlimb Differences among Overweight Breast Cancer Survivors with Lymphedema by Lorraine T. Dean, Anagha Kumar, Taehoon Kim, Matthew Herling, Justin C. Brown, Zi Zhang, Margaret Evangelisti, Renata Hackley, Jiyoung Kim, Andrea Cheville, Andrea B. Troxel, J. Sanford Schwartz, Kathryn H. Schmitz

    Published 2016-01-01
    “…Black cancer survivors are more likely to have high BMI than White cancer survivors. While observational analyses suggest up to 2.2 times increased risk of BCRL onset for Black breast cancer survivors, no studies have explored race or other social factors that may affect BCRL severity, operationalized by interlimb volume difference (ILD). …”
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  14. 24314

    Investigation on True Stress-Strain Curves of Flat and Corner Regions of Cold-Formed Section Using 3D Digital Image Correlation Method by Bo Xu, Junwu Xia, Renwei Ma, Jian Wang, Xiaomiao Chen, Hongfei Chang, Lihai Zhang

    Published 2019-01-01
    “…The experimental results indicate that the tensile secondary-hardening phenomenon at the plastic strain stage was observed in the true stress-strain curves of flat coupons, and initial strain hardening behavior was produced in that of corner coupons. …”
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  15. 24315

    Removal of Matrix Interferences by Nano-MgO and Co-Adsorbents for Accurate Multi-Pesticide Residue Analysis in the Chinese Medicinal Herb, Paeoniae Radix Alba by Chunyu Wang, Xinquan Wang, Jiao Wang, Shanshan Di, Zhiwei Wang, Hao Xu, Huiyu Zhao, Changshan Zhao, Peipei Qi

    Published 2021-01-01
    “…The method was systematically validated under optimal conditions in five different kinds of PRA samples; good linearity was observed in the concentration range of 0.5–250 μg/L or 1–250 μg/L. …”
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  16. 24316

    Mdivi-1 Protects CD4+ T Cells against Apoptosis via Balancing Mitochondrial Fusion-Fission and Preventing the Induction of Endoplasmic Reticulum Stress in Sepsis by You Wu, Yong-Ming Yao, He-Liang Ke, Lan Ying, Yao Wu, Guang-Ju Zhao, Zhong-Qiu Lu

    Published 2019-01-01
    “…The potential mechanism underlying the protective effect of Mdivi-1 involved Mdivi-1 reestablishing mitochondrial fusion-fission balance in sepsis, as reflected by the expression of the mitofusin 2 (MFN2) and optic atrophy 1 (OPA1) , Drp1 translocation, and mitochondrial morphology, as observed by electron microscopy. Moreover, Mdivi-1 treatment reduced reactive oxygen species (ROS) production and prevented the induction of endoplasmic reticulum stress (ERS) and associated apoptosis. …”
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  17. 24317

    First Clinical Evidence About the Use of a New Silver-Coated Titanium Alloy Instrumentation to Counteract Surgical Site Infection at the Spine Level by Lucrezia Leggi, Silvia Terzi, Maria Sartori, Francesca Salamanna, Luca Boriani, Emanuela Asunis, Cristiana Griffoni, Gianluca Giavaresi, Alessandro Gasbarrini

    Published 2025-01-01
    “…This study is aimed at assessing the effectiveness of a new treatment approach for SSIs that includes a single-stage approach with the removal of the previous hardware, accurate debridement, and single-stage instrumentation using a silver fixation system (SFS) made of titanium alloy coated with silver (Norm Medical, Ankara, Turkey) by means of a retrospective observational study. <b>Materials and Methods:</b> The demographic data, type of surgery, comorbidities, pathogens, and treatment details of consecutive patients with an SSI who received the SFS between 2018 and 2021 were extracted from their medical records and analyzed. …”
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  18. 24318

    Effect of sleep quality on the severity of perimenstrual symptoms in Japanese female students: a cross-sectional, online survey by Yukio Urabe, Makoto Komiya, Noriaki Maeda, Satoshi Arima, Tsubasa Tashiro, Rami Mizuta, Sakura Oda, Takaaki Nagasawa, Koichi Naito

    Published 2025-02-01
    “…Objectives To investigate the relationship between sleep quality and perimenstrual symptoms among Japanese female students.Design Observational, cross-sectional, online surveySetting We used an online questionnaire to collate responses from Japanese female students on sleep quality and perimenstrual symptoms.Participants A total of 298 female students aged 18–25 years in Japan were included in this study.Primary and secondary outcome measures The Menstrual Distress Questionnaire (MDQ) was used to assess the severity of perimenstrual symptoms for three periods—premenstrual, menstrual and postmenstrual—and the Japanese version of the Pittsburgh Sleep Quality Index was used to assess sleep quality. …”
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  19. 24319

    The Coexistence of Colorectal Polyps in the Right Colon Increases the Malignant Risk of Laterally Spreading Tumors by Xiaonan Shen, Yao Zhang, Yunjia Zhao, Xiaobo Li, Zhizheng Ge, Hua Xiong, Danfeng Sun, Qinyan Gao, Yun Cui, Xiaoyu Chen, Yingxuan Chen, Jingyuan Fang

    Published 2020-01-01
    “…The coexistence of colorectal polyps with laterally spreading tumors (LSTs) is commonly observed during colonoscopy. However, there are rare studies that assess the malignant risks for LSTs with colorectal polyps, which might largely contribute to further strategies of treatment and follow-up plans in LSTs. …”
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  20. 24320

    Examining reliability of WHOBARS: a tool to measure the quality of administration of WHO surgical safety checklist using generalisability theory with surgical teams from three New... by Jennifer M Weller, Carmen Skilton, Derryn A Gargiulo, Oleg N Medvedev, Simon J Mitchell, Alan F Merry

    Published 2019-01-01
    “…In this context, extending reliability refers to establishing generalisability of the tool scores across populations of teams and raters by accounting for the relevant sources of measurement errors.Design Cross-sectional random effect measurement design assessing surgical teams by the five items on the three Checklist phases, and at three sites by two trained raters simultaneously.Setting The data were collected in three tertiary hospitals in Auckland, New Zealand in 2016 and included 60 teams observed in 60 different cases with an equal number of teams (n=20) per site. …”
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