Dendrobium chrysotoxum Lindl. Alleviates Diabetic Retinopathy by Preventing Retinal Inflammation and Tight Junction Protein Decrease by Zengyang Yu, Chenyuan Gong, Bin Lu, Li Yang, Yuchen Sheng, Lili Ji, Zhengtao Wang

“…Diabetic retinopathy (DR) is a serious complication of diabetes mellitus. This study aimed to observe the alleviation of the ethanol extract of Dendrobium chrysotoxum Lindl. …”
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Genes Involved in the Transcriptional Regulation of Pluripotency Are Expressed in Malignant Tumors of the Uterine Cervix and Can Induce Tumorigenic Capacity in a Nontumorigenic Cel... by Graciela Ruiz, Heriberto A. Valencia-González, Delia Pérez-Montiel, Felipe Muñoz, Rodolfo Ocadiz-Delgado, Jorge Fernández-Retana, Carlos Pérez-Plasencia, Osbaldo Reséndis-Antonio, Patricio Gariglio, Alejandro García-Carrancá

“…Also, cancer stem cell-enriched cultures grown as sphere cultures showed overexpression of OSKM-N genes. Importantly, we observed that lentiviral-mediated transduction of these factors confers, to a nontumorigenic immortalized human cell line, properties of cancer stem cells as the ability to form tumors in a mouse model. …”
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Oncostatin M and TLR-4 Ligand Synergize to Induce MCP-1, IL-6, and VEGF in Human Aortic Adventitial Fibroblasts and Smooth Muscle Cells by David Schnittker, Karen Kwofie, Ali Ashkar, Bernardo Trigatti, Carl D. Richards

“…Such effects were not observed with other gp130 cytokines. Signalling pathways including STATs, MAPKinases, and NFκB were activated, and LPS induced steady state mRNA levels of the OSM receptor chains OSMRβ and gp130. …”
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Une pompe hydraulique romaine en bois en contexte d’incendie à Reims/Durocortorum by Cyril Driard

“…It also suggests that they would have had spare parts or additional modules, or even several other similar devices at their disposal. These observations are reminiscent of the letter to Trajan from Pliny the Younger (Letters, Book X) concerning the fight against fires in urban areas. …”
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Reactive nitrogen in and around the northeastern and mid-Atlantic US: sources, sinks, and connections with ozone by M. Huang, M. Huang, G. R. Carmichael, K. W. Bowman, I. De Smedt, A. Colliander, M. H. Cosh, S. V. Kumar, A. B. Guenther, S. J. Janz, R. M. Stauffer, A. M. Thompson, N. M. Fedkin, R. J. Swap, J. D. Bolten, A. T. Joseph

“…Modeled surface O<span class="inline-formula">₃</span> persistently agrees well with observations, with root mean square errors staying within 4–7 ppbv for individual years in May–June–July. …”
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First-line chemotherapy with selective internal radiation therapy for intrahepatic cholangiocarcinoma: The French ACABi GERCOR PRONOBIL cohort by Nicolas Adamus, Julien Edeline, Julie Henriques, Nadim Fares, Thierry Lecomte, Anthony Turpin, Dewi Vernerey, Mathilde Vincens, Brice Chanez, David Tougeron, Christophe Tournigand, Eric Assenat, Matthieu Delaye, Sylvain Manfredi, Olivier Bouché, Nicolas Williet, Angelique Vienot, Lorraine Blaise, Léo Mas, Cindy Neuzillet, Alice Boilève, Gaël S. Roth

“…An improvement of progression-free survival, overall survival, tumor response and secondary surgical resection rate was observed in favor of chemo-SIRT, before adjustment and after inverse probability of treatment weighting propensity score analyses. …”
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Global, regional, and national trends in drug use disorder mortality rates across 73 countries from 1990 to 2021, with projections up to 2040: a global time-series analysis and mod... by Soeun Kim, Hayeon Lee, Selin Woo, Hyeri Lee, Jaeyu Park, Tae Kim, Guillaume Fond, Laurent Boyer, Masoud Rahmati, Lee Smith, Guillermo F. López Sánchez, Elena Dragioti, Christa J. Nehs, Jinseok Lee, Hyeon Jin Kim, Jiseung Kang, Dong Keon Yon

“…Interpretation: An increasing trend in global DUD mortality was observed from 1990 to 2021, especially in HICs. Future DUD deaths were also predicted to increase until 2040 at the global level. …”
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Leptomeningeal Cells Transduce Peripheral Macrophages Inflammatory Signal to Microglia in Reponse to Porphyromonas gingivalis LPS by Yicong Liu, Zhou Wu, Xinwen Zhang, Junjun Ni, Weixian Yu, Yanmin Zhou, Hiroshi Nakanishi

“…LPS-stimulated leptomeningeal cells were significantly higher than those after P.g. LPS alone. These observations suggest that leptomeninges serve as an important route for transducing inflammatory signals from macrophages to microglia by secretion of proinflammatory mediators during chronic periodontitis. …”
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Identification and functional characterization of the MYB transcription factor GmMYBLJ in soybean leaf senescence by Guohua Bao, Xiao Xu, Jing Yang, Juanjuan Liu, Tianran Shi, Xiaoxuan Zhao, Xuyan Li, Shaomin Bian

“…The GmMYBLJ protein is localized in the nucleus, and a high accumulation of its transcripts was observed in nodules and embryos. Notably, GmMYBLJ was highly expressed in soybean senescent leaves and was transcriptionally induced by dark or NaCl treatment, as confirmed by histochemical GUS staining analysis. …”
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Fractional amplitude of low-frequency fluctuations during music-evoked autobiographical memories in neurotypical older adults by Teresa Lesiuk, Kaitlyn Dillon, Giulia Ripani, Ioannis Iliadis, Gabriel Perez, Bonnie Levin, Xiaoyan Sun, Roger McIntosh

“…In addition to a T1 structural scan, neuroimaging data were collected while participants listened to familiar music (MEAM retrieval) versus unfamiliar music.ResultsWhen listening to familiar compared to unfamiliar music, greater fALFF activation patterns were observed in the right parahippocampal gyrus, controlling for age and GMV. …”
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Analysis of Uneven Settlement of Long-Span Bridge Foundations Based on SBAS-InSAR by Kaixuan Zhang, Weifo Xiao, Haojie Zhu, Shaowei Ning, Shenjiang Huang, Dongxing Jin, Rong A, Bhesh Raj Thapa

“…We then investigated the relationship between these settlement patterns and various environmental factors, including geological conditions, Sediment Transport Index (STI), Topographic Wetness Index (TWI), precipitation, and temperature. The observed settlement patterns were attributed to the combined effects of stratigraphic heterogeneity, dynamic hydrological conditions, and seasonal climate variations. …”
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Transcatheter Closure of Patent Ductus Arteriosus in Elderly Patients: Initial and One-Year Follow-Up Results—Do We Have the Proper Device? by Michal Galeczka, Malgorzata Szkutnik, Jacek Bialkowski, Sebastian Smerdzinski, Mateusz Knop, Adam Sukiennik, Roland Fiszer

“…All but three patients were symptomatic, with most in NYHA II (n = 14) and III (n = 11) class; pulmonary hypertension (n = 22), arterial hypertension (n = 22), duct calcifications (n = 17), atrial fibrillation (n = 15), significant mitral regurgitation (n = 5), and decompensated renal failure (n = 2) were observed. Different devices were applied depending on PDA morphology; nitinol wire mesh occluders with symmetrical articulating discs have been the most used in recent years (n = 11). …”
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Comparative analysis of metabolic, reproductive, and sub-clinical mastitis in pure Holstein-Friesian and Sahiwal-crossbred cows by S. M. Khan, R. U. Khan, S. Naz, I. A. Alhidary, N. K. Momand, R. Tiwari

“…However, no significant differences were observed in cholesterol or triglyceride levels across the breeds, suggesting consistent metabolic management. …”
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Use of ascorbic acid (vitamin C) and alpha tocopherol (vitamin E) as adjuvants in the treatment of neuropathic pain by Fernando Antonio Silva de Azevedo-Filho, Yasmim Machado Chaves de Castro, Marcos Pinho Cerqueira, Thiago Arruda Rodrigues, Yussef Ali-Abdouni, Patrícia Maria de Moraes Barros Fucs

“…CONCLUSION: It was observed that the use of vitamin C and E in combination with pregabalin had a greater analgesic effect than the use of pregabalin alone.…”
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The impact of creatine supplementation on the development of kidney disease – literature review by Mateusz Matczak, Karol Jasiński, Aleksandra Broda, Kacper Hoksa, Krzysztof Jodłowski, Ewa Dubniewicz, Paula Majewska, Alicja Staszek, Wiktoria Łoskot, Jan Szwech

“…While no direct renal impairment has been observed, caution is essential for those with kidney conditions. …”
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Early amiodarone or lidocaine administration during in-hospital cardiac arrest caused by shockable rhythms by Rafael C. Paganoni, Jack C. Pluenneke, Adham M. Mohamed, Charles H. Hayes, III, Carole E. Freiberger-O’Keefe, Paul S. Chan

“…Methods: This was a retrospective, multi-center, single health system, observational cohort study of patients with an IHCA caused by VF/pVT and who received amiodarone or lidocaine during 2014–2024. …”
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Biocompatible Heterogeneous Packaging and Laser-Assisted Fluid Interface Control for In Situ Sensor in Organ-on-a-Chip by Yu-Hsuan Lin, Shing-Fung Lau, Yen-Pei Lu, Kuo-Cheng Huang, Chien-Fang Ding, Yu-Hsiang Tang, Hsin-Yi Tsai

“…The results demonstrate that through precise control of processing parameters, the wettability of the material can be tuned freely within a contact angle range of 60° to 110°. Morphological observations and MTT assays confirmed that the material and the processing methods do not induce cytotoxicity. …”
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Effect of pocket compression device on pocket hematoma after cardiac implantable electronic device implantation by Narawudt Prasertwitayakij, Jakkapun Yanyongmathe, Natnicha Pongbangli, Teerapat Nantsupawat, Siriluck Gunaparn, Cheeranun Pisespongsa, Chanya Tawaditap, Arintaya Phrommintikul, Wanwarang Wongcharoen

“…Rates of grade 2 hematoma were similarly low and comparable (2.5% vs. 0.8%, p = 0.368), with no grade 3 hematomas observed. Skin reactions and patient comfort were similar between groups. …”
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Properties of new polycationic bacteriochlorin photosensitizers: cytotoxicity and interaction with biofilms by Irina Tiganova, Yulia Zhizhimova, Eteri Tolordava, Elena Makarova, Natalia Shevlyagina, Alexander Barmashov, Maria Baryshnikova, Vladimir Zhukhovitsky, Yulia Romanova

“…After incubation of P. aeruginosa 32 biofilms with tetracationic BCl-6 and BCl-5 without irradiation, gross disturbances in the structure of the biofilm matrix were observed by SEM, as well as a significant reduction of Alcian blue staining and polysaccharides in the matrix. …”
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Improved Function After Anterior Controllable Antedisplacement and Fusion for Cervical Ossification of Posterior Longitudinal Ligament: A Long‐Term Follow‐Up by Yangyang Shi, Kaiqiang Sun, Linhui Han, Chen Yan, Jinyu Wang, Jingyun Yang, Yuan Wang, Ximing Xu, Jingchuan Sun, Jiangang Shi

“…Improvements in Cobb angle and invasion rate were observed right after the operation and were maintained for 2 years thereafter. …”
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