A New MEN2 Syndrome with Clinical Features of Both MEN2A and MEN2B Associated with a New RET Germline Deletion by Carlotta Giani, Teresa Ramone, Cristina Romei, Raffaele Ciampi, Alessia Tacito, Laura Valerio, Laura Agate, Clara Ugolini, Michele Marinò, Fulvio Basolo, Alessandro Franchi, Simona Borsari, Angela Michelucci, Cesare Selli, Gabriele Materazzi, Filomena Cetani, Rossella Elisei

“…A 7-year-old girl, previously treated for a pelvic plexiform neurofibroma, arrived at our observation with a peculiar MEN2B syndrome and with HPTH. …”
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Age and moisture affect the relationship between competition and tree growth by Xinyu Han, Lushuang Gao, Mingqian Liu, Yihong Zhu, Keda Cui, Xinyu Zhang, Xiuhai Zhao, Ruibo Zhang, Klaus von Gadow, Yiyu Tian, Kangchen Wang

“…Our analysis is based on comprehensive data collected from natural forests of Xing'an larch (Larix gmelinii) located in the northeastern region of China. We observed that competition indirectly impacts tree growth by diminishing crown size, and this influence is modulated by both tree age and environmental moisture conditions. …”
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Predictive role of ABC transporters in the efficacy of enfortumab vedotin for urothelial carcinoma by Toshiki Kijima, Atsuko Takada‐Owada, Hiroki Shimoda, Hidetoshi Kokubun, Toshitaka Uematsu, Kohei Takei, Hironori Betsunoh, Masahiro Yashi, Kazuyuki Ishida, Takao Kamai

“…Furthermore, a decrease in Nectin‐4 expression and an increase in ABC transporter expression were observed as the disease progressed from non‐muscle‐invasive to muscle‐invasive and metastatic. …”
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Investigation of TGFβ1-Induced Long Noncoding RNAs in Endothelial Cells by Krishna K. Singh, Pratiek N. Matkar, Adrian Quan, Laura-Eve Mantella, Hwee Teoh, Mohammed Al-Omran, Subodh Verma

“…This is the first lncRNA and mRNA transcriptome profile of TGFβ-mediated changes in human endothelial cells. These observations may reveal potential new targets of TGFβ in endothelial cells and novel therapeutic avenues for cardiovascular disease-associated endothelial dysfunction.…”
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Emission Characteristics of PCDD/Fs, Heavy Metals, and Nuclides during Incineration of Waste Resins Containing Nuclides by Yuhan Feng, Yingzhe Du, Shiying Li, Lili Li, Shi Feng, Kunfeng Li, Mingxiu Zhan, Jinqing Wang, Xu Xu, Peng Lin

“…Furthermore, the low nuclide concentration was observed in the flue gas. Almost no solid residue was generated due to sufficient incineration in the tubular furnace. …”
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Individualized autoregulation-guided arterial blood pressure management in neurocritical care by Jonathan R. Gomez, Bhagyashri U. Bhende, Rohan Mathur, L. Fernando Gonzalez, Vishank A. Shah

“…Many guidelines recommend universal static ABP targets; however, in patients with altered CA, these targets may make them susceptible to hypoperfusion and further neurological injury. Based on this observation, there has been much investigation on individualized ABP goals and their effect on clinical outcomes. …”
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The optimal wind speed product selection for wind energy assessment under multi-factor constraints by Xiaohui Li, Yunhao Chen, Kangning Li, Shengjun Gao, Ying Cui

“…Major findings are summarized as follows: (1) CN05.1 is the most suitable product for characterizing wind speed across mainland China under multi-factor constraints, followed by ERA5-land. (2) The wind speed volatility of all six datasets is underestimated compared to actual observations. Among them, JRA55 demonstrates the best capability to depict wind speed volatility in China, followed by MERRA2 and ERA5-land. (3) ERA5-land is the optimal product for wind energy resource assessments across mainland China, offering relatively accurate characterizations of both wind speed and wind speed volatility.…”
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Giant Cell Tumor of The Proximal Phalanx of The Index Finger of The Hand: A Rare Case Report by Mouli Edward, Ferdiansyah Mahyudin, Muhammad Hardian Basuki, Yunus Basrewan, Caesar Haryo Bimoseno

“…There was no recurrence observed. Conclusion: Despite the tendency for hand GCT to be more aggressive, local resection and reconstruction using an allograft with adjuvant hydrogen peroxide can reduce recurrence and disability.…”
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Etodolac Single Dose Metabolic Profile Elucidation: Pharmacokinetics and Adverse Events in Healthy Volunteers by Karen Sánchez-Luquez, Anne Michelli Reis Silveira, Salvador Sánchez-Vinces, Alex Ap. Rosini Silva, Joyce Barreto, Rhubia Bethania Socorro Lemos de Brito, Caroline de Moura Garcia, Ana Lais Vieira, Marcia Ap. Antonio, Patrícia de Oliveira Carvalho

“…Results: Correlations were observed between metabolomic profiles and pharmacokinetic parameters as well as clinical characteristics. …”
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Comparing simple and functional jejunal interposition with preserved duodenal passage after total gastrectomy by Xue-Lu Zhou, Yan-Qing Deng, Pei-Jie Zhang, Hai Huang, Huan-Bin Zhang, Hong-Shuai Li, You-Hua Wang, Jian-Hua Luo

“…Results: There were no significant differences observed between the FJI group and the SJI group in terms of primary and secondary endpoints. …”
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In Vitro Antibacterial and Antibiofilm Activity of Lippia alba Essential Oil, Citral, and Carvone against Staphylococcus aureus by Emanuela Mesquita Porfírio, Hider Machado Melo, Antônio Matheus Gomes Pereira, Theodora Thays Arruda Cavalcante, Geovany Amorim Gomes, Mário Geraldo de Carvalho, Renata Albuquerque Costa, Francisco Eduardo Aragão Catunda Júnior

“…Potential inhibition (100%) of S. aureus biofilm formation at the concentration of 0.5 mg mL−1 of all EOs was observed. However, the elimination of biofilm cells was confirmed at concentrations of 1 mg mL−1, 2 mg mL−1, 2 mg mL−1, and 0.5 mg mL−1 for LA1EO, LA2EO, LA3EO, and citral, respectively. …”
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pDC Activation by TLR7/8 Ligand CL097 Compared to TLR7 Ligand IMQ or TLR9 Ligand CpG by Jing Wu, Shuang Li, Tete Li, Xinping Lv, Mingyou Zhang, Guoxia Zang, Chong Qi, Yong-Jun Liu, Liang Xu, Jingtao Chen

“…Our previous study demonstrated that pDCs activated by the TLR7 ligand imiquimod (IMQ) and the TLR9 ligand CpG A can kill breast cancer cells in vitro and inhibit tumor growth in vivo. Moreover, we observed a distinctive morphological, phenotypic change in pDCs after activation by IMQ and CpG A. …”
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Portable Handheld Slit-Lamp Based on a Smartphone Camera for Cataract Screening by Shenming Hu, Hong Wu, Xinze Luan, Zhuoshi Wang, Mary Adu, Xiaoting Wang, Chunhong Yan, Bo Li, Kewang Li, Ying Zou, Xiaoya Yu, Xiangdong He, Wei He

“…The phone’s photo taking function is used in capturing the image of the eyes lens to replace the observation system of the desktop slit-lamp. A simplified slit light band was designed. …”
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The effects of different carbon-fiber plate shapes in shoes on lower limb biomechanics following running-induced fatigue by Yufan Xu, Chengyuan Zhu, Yufei Fang, Zhenghui Lu, Zhenghui Lu, Zhenghui Lu, Yang Song, Chen Hu, Dong Sun, Yaodong Gu

“…The activation level of the tibialis anterior (TA) was significantly higher when wearing “Curve” in pre-fatigue compared to “Flat”, whereas the opposite was observed post-fatigue. The curved CFP altered the bending angle of the forefoot, thereby significantly reducing the joint angles and joint moments of the hip and knee.…”
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Children with autistic spectrum disorder can imagine actions— what can this reveal about the Broken Mirror Hypothesis? by Jessica Galli, Jessica Galli, Laura Dusi, Gioacchino Garofalo, Gioacchino Garofalo, Alessandra Brizzi, Michela Gritti, Federica Polo, Elisa Fazzi, Elisa Fazzi, Giovanni Buccino, Giovanni Buccino

“…ObjectiveThis study investigated whether children with Autistic Spectrum Disorder (ASD) can imagine object directed actions similarly to their typically developed (TD) peers.Study designWe tested the ability to imagine goal directed actions in children with ASD (n = 18) and TD (n = 18) peers by means of VMIQ-2 questionnaire and a novel behavioral task, in which children were requested to imagine some daily actions, after seeing them through videoclips presented on a computer screen. Observed actions lasted 4 s and children were requested to follow the same time course during imagination. …”
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Cognition and objective sleep quality in post-COVID-19 patients by Anna Carnes-Vendrell, Gerard Piñol-Ripoll, Adriano Targa, Nuria Tahan, Mar Ariza, Neus Cano, Neus Cano, Barbara Segura, Barbara Segura, Barbara Segura, Barbara Segura, Carme Junque, Carme Junque, Carme Junque, Carme Junque, Javier Béjar, Cristian Barrue, Nautilus Project Collaborative Group, Maite Garolera, Maite Garolera, Linh Viet Nguyen, Vanesa Arauzo, Jose A. Bernia, Marta Balague-Marmaña, Berta Valles-Pauls, Jesús Caballero, Ester Gonzalez-Aguado, Carme Tayó-Juli, Eva Forcadell-Ferreres, Silvia Reverte-Vilarroya, Susanna Forné, Anna Bartes-Plans, Jordina Muñoz-Padros, Jose A, Anna Prats-Paris Muñoz-Moreno, Inmaculada Rico, Nuria Sabé, Marta Almeria, Laura Casas, Maria José Ciudad, Anna Ferré, Tamar Garzon, Manuela Lozano, Marta Cullell, Sonia Vega, Sílvia Alsina, Maria J. Maldonado-Belmonte, Susana Vazquez-Rivera, Eva Baillès, Sandra Navarro, Ayoze González Hernández, Yaiza Molina, Victoria Olive, Silvia Cañizares

“…We also found a correlation between the total sleep time of both measures (actigraphy and PSQI), but we did not observe correlations between objective and subjective parameters of latency and sleep efficiency. …”
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Lesser Toxicities of Belotecan in Patients with Small Cell Lung Cancer: A Retrospective Single-Center Study of Camptothecin Analogs by Yeon Hee Park, Chae Uk Chung, Bo Mi Park, Myoung Rin Park, Dong Il Park, Jae Young Moon, Hee Sun Park, Jin Hwan Kim, Sung Soo Jung, Ju Ock Kim, Sun Young Kim, Jeong Eun Lee

“…Significant differences between belotecan and topotecan were also observed for grade 4/5 lung infection (3.2% versus 10.8%, resp.; p=0.003), all-grade headache (3.2% versus 10.8%, resp.; p=0.017), and grade 4/5 increased liver enzymes (0.5% versus 4.6%, resp.; p=0.023). …”
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Effect of Nb and Si Content on Phase Stability, Microstructure and Mechanical Properties of Sintered Ti–Nb–Si Alloys by Derek Manoel Luup Carvalho, Deivison Daros Paim, Isadora Schramm Deschamps, Claudio Aguilar, Aloísio Nelmo Klein, Francisco Cavilha Neto, Guilherme Oliveira Neves, Cristiano Binder

“….% of Si improved relative density, with no benefits observed at 0.60 wt.% Si. Electron microscopy showed the presence of β phase grains, and grains with β + α intragranular structures and precipitates. …”
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A prognostic model of 8-T/B cell receptor-related signatures for hepatocellular carcinoma by Xuan Zuo, Hui Li, Shi Xie, Mengfen Shi, Yujuan Guan, Huiyuan Liu, Rong Yan, Anqi Zheng, Xueying Li, Jiabang Liu, Yifan Gan, Haiyan Shi, Keng Chen, Shijie Jia, Guanmei Chen, Min Liao, Zhanhui Wang, Yanyan Han, Baolin Liao

“…Patients were divided into high-risk and low-risk groups based on the median of the risk scores. We observed that tumor differentiation was worse while the fibrinogen concentration was higher in the high-risk group of patients. …”
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Regenerative Potential of Mesenchymal Stromal Cells: Age-Related Changes by Flavia Bruna, David Contador, Paulette Conget, Benjamín Erranz, Claudia L. Sossa, Martha L. Arango-Rodríguez

“…Significant differences in the wound closure kinetic, quality, and healing of skin regenerated were observed in lesions which received BM-MSCs from different ages or their acd-MSCs compared to lesions which received vehicle. …”
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