Effect of flipped classroom method on the reflection ability in nursing students in the professional ethics course; Solomon four-group design by Mohammad Rasool Khazaei, Eshagh Moradi, Azizeh Barry, Mohammad Hasan Keshavarzi, Akram Hashemi, Ghobad Ramezani, Atefeh Zabihi Zazoli, Farzaneh Farzadnia

“…A significant difference was observed between the amount of reflection of the experimental and control groups. …”
Get full text

Simultaneous exposure to microplastics and heavy metal lead induces oxidative stress, histopathological damage, and immune dysfunction in marine mussel Mytilus coruscus by Chuanyue Chen, Xueer Wang, Yingrong Jin, Yinchang Yao, Suchang Li, Zhi Liao, Xiaolin Zhang, Xiaojun Yan

“…We found that MPs alone or in combination with Pb significantly decreased the respiration and filtration rates of the mussels (p < 0.05). Histological observations revealed varying extents of damage to the gill and digestive gland caused by a single exposure to MPs, which was aggravated by co-exposure to Pb. …”
Get full text

Metabolic and inflammatory status in prepuberty and early adulthood for individuals with a history of extrauterine growth restriction: a cohort study by Laura Palomino-Fernández, Inmaculada Velasco, Belén Pastor-Villaescusa, Katherine Flores-Rojas, María de la Cruz Rico, Juan Roa, Ángel Gil, Mercedes Gil-Campos

“…In contrast, arterial hypertension was observed in 36% of prepubertal children compared with 18% of postpubertal young adults. …”
Get full text

Revisiting the anatomy of inferior extensor retinaculum of foot and ankle, a study based on fifty embalmed adult cadaveric lower extremities by M. Praveen Shenoy, Mangala M. Pai, B.V. Murlimanju, Rajanigandha Vadgaonkar, Latha V. Prabhu, M.D. Prameela

“…Results: The present study observed that, the anatomy of IER is complex wherein multiple septa of varied thickness arise from its undersurface from both the stem and limbs, defining its compartments. …”
Get full text

Optimizing the growth conditions of superconducting MoSi thin films for single photon detection by Stefanie Grotowski, Lucio Zugliani, Björn Jonas, Rasmus Flaschmann, Christian Schmid, Stefan Strohauer, Fabian Wietschorke, Niklas Bruckmoser, Manuel Müller, Matthias Althammer, Rudolf Gross, Kai Müller, Jonathan Finley

“…For Mo concentrations above 81% the crystalline phase $$\hbox {Mo}_\text {3}$$ Mo 3 Si is observed in grazing incidence X-ray diffraction measurements. …”
Get full text

The Chromosome 9p21 CVD- and T2D-Associated Regions in a Norwegian Population (The HUNT2 Survey) by Øyvind Helgeland, Jens K. Hertel, Anders Molven, Helge Ræder, Carl G. P. Platou, Kristian Midthjell, Kristian Hveem, Ottar Nygård, Pål R. Njølstad, Stefan Johansson

“…Conditioning on the lead SNPs in the region, we observed two suggestive independent single SNP association signals for MI, rs2065501  (P=0.03) and rs3217986  (P=0.04). …”
Get full text

Gli1+ Cells Residing in Bone Sutures Respond to Mechanical Force via IP3R to Mediate Osteogenesis by Xiaoyao Huang, Zihan Li, Peisheng Liu, Meiling Wu, An-qi Liu, Chenghu Hu, Xuemei Liu, Hao Guo, Xiaoxue Yang, Xiaohe Guo, Bei Li, Xiaoning He, Kun Xuan, Yan Jin

“…Besides, we found mechanical force-induced osteogenesis through inositol 1,4,5-trisphosphate receptor (IP3R), and we observed for the first time that inhibition of Gli1 suppressed an increase in mechanical force-induced IP3R overexpression, suggesting that Gli1+ cells participate in mechanical force-induced osteogenesis through IP3R. …”
Get full text

Hospital frailty risk score predicts graft failure severe infection and mortality in hospitalized kidney transplant recipients from 2010 to 2018 US data by Lumin Chen, Feifan Chu, Hangbin Ma, Zujie Chen, Yuning Ma, Qiwei Ji, Hao Zhou

“…In this retrospective observational study, we extracted data on 185,742 patients from the National Inpatient Sample (NIS) database in the United States. …”
Get full text

Identifying key risks to the stability of Ukrainian universities during wartime by Olha Doronina, Liudmyla Yurchyshena, Kseniia Bondarevska, Ihor Vechirko, Tetiana Kulinich

“…Non-traditional financial measures, such as unpaid leave and allowance reductions, were observed as short-term crisis strategies but require further evaluation to assess their long-term impact. …”
Get full text

What Makes Umbilical Cord Tissue-Derived Mesenchymal Stromal Cells Superior Immunomodulators When Compared to Bone Marrow Derived Mesenchymal Stromal Cells? by R. N. Bárcia, J. M. Santos, M. Filipe, M. Teixeira, J. P. Martins, J. Almeida, A. Água-Doce, S. C. P. Almeida, A. Varela, S. Pohl, K. E. J. Dittmar, S. Calado, S. I. Simões, M. M. Gaspar, M. E. M. Cruz, W. Lindenmaier, L. Graça, H. Cruz, P. E. Cruz

“…To elucidate the potency differences observed between UCX and BM-MSCs, gene expression related to immune modulation was analysed in both cell types. …”
Get full text

Longitudinal mitochondrial bioenergetic signatures of blood monocytes and lymphocytes improve during treatment of drug-susceptible pulmonary tuberculosis patients by Bridgette M. Cumming, Kelvin W. Addicott, Fernanda Maruri, Fernanda Maruri, Vanessa Pillay, Rukaya Asmal, Sashen Moodley, Beatriz Barreto-Durate, Beatriz Barreto-Durate, Mariana Araújo-Pereira, Mariana Araújo-Pereira, Matilda Mazibuko, Zoey Mhlane, Nikiwe Mbatha, Khadija Khan, Senamile Makhari, Farina Karim, Lauren Peetluk, Alexander S. Pym, Mahomed Yunus S. Moosa, Yuri F. van der Heijden, Yuri F. van der Heijden, Yuri F. van der Heijden, Timothy S. Sterling, Timothy S. Sterling, Bruno B. Andrade, Bruno B. Andrade, Alasdair Leslie, Alasdair Leslie, Alasdair Leslie, Adrie J. C. Steyn, Adrie J. C. Steyn, Adrie J. C. Steyn

“…Treatment of TB patients restored the % spare respiratory capacity (%SRC) of the circulating lymphocytes to that observed in non-TB and non-HIV infected controls by 12 months. …”
Get full text

Exogenous dsRNA triggers sequence-specific RNAi and fungal stress responses to control Magnaporthe oryzae in Brachypodium distachyon by Ying Zheng, Benjamin Moorlach, Desiree Jakobs-Schönwandt, Anant Patel, Chiara Pastacaldi, Stefan Jacob, Ana R. Sede, Manfred Heinlein, Minna M. Poranen, Karl-Heinz Kogel, Maria Ladera Carmona

“…Notably, the sequence-unspecific effect of dsRNA depends on higher doses, while pure sequence-specific effects were observed at low concentrations of dsRNA ( < 0.03 ng/µL). …”
Get full text

Development of an m6A-Related lncRNAs Signature Predicts Tumor Stemness and Prognosis for Low-Grade Glioma Patients by Dahua Xu, Peihu Li, Chunrui Zhang, Yutong Shen, Jiale Cai, Qingchen Wei, Meng Cao, Zhizhou Xu, Deng Wu, Hong Wang, Xiaoman Bi, Bo Wang, Kongning Li

“…Significant correlations were observed between the risk score and tumor stemness. …”
Get full text

Experimental Study on the Permeability of Weakly Cemented Rock under Different Stress States in Triaxial Compression Tests by Gangwei Fan, Mingwei Chen, Dongsheng Zhang, Zhen Wang, Shizhong Zhang, Chengguo Zhang, Qizhen Li, Bobo Cao

“…Analyses based on scanning electron microscope (SEM) observations and mineral composition indicate that the samples are rich in clay minerals such as montmorillonite and kaolin, whose inherent properties of hydroexpansiveness and hydrosliming can be considered the dominant factors contributing to the seepage properties of weakly cemented rock with low permeability.…”
Get full text

FGFR antagonists restore defective mandibular bone repair in a mouse model of osteochondrodysplasia by Anne Morice, Amélie de La Seiglière, Alexia Kany, Roman H. Khonsari, Morad Bensidhoum, Maria-Emilia Puig-Lombardi, Laurence Legeai Mallet

“…Lastly, we found that treatment with a tyrosine kinase inhibitor (BGJ398, infigratinib) or a C-type natriuretic peptide (BMN111, vosoritide) fully rescued the defective endochondral bone repair observed in Hch mice. Taken as a whole, our findings show that FGFR3 is a critical orchestrator of bone repair and provide a rationale for the development of potential treatments for patients with FGFR3-osteochondrodysplasia.…”
Get full text

Epidemiological characterization of congenital heart disease at different altitudes in Ecuador: a four-year retrospective study in a pediatric referral hospital by Juan S. Izquierdo-Condoy, Fabian D. Arias-Rodríguez, Walter I. Díaz-Chamba, Diego A. Mena-Noroña, Lizbeth Cueva Toaquiza, Beanjuly Espín-Sambache, Emilia J. Valdivieso-Andrade, Amanda Cangas-Isacaz, Susana García-Cañarte, Mario Rubio-Niera, Esteban Ortiz-Prado

“…Among cyanotic CHD, Tetralogy of Fallot was predominant (28.1%). Mortality was observed in 5.3% of patients, with a higher rate among acyanotic CHD (p &lt; 0.001).ConclusionMost cases of CHD were of the acyanotic type, predominantly affecting female patients. …”
Get full text

The Expression Level of mRNA, Protein, and DNA Methylation Status of FOSL2 of Uyghur in XinJiang in Type 2 Diabetes by Jun Li, Siyuan Li, Ying Hu, Guolei Cao, Siyao Wang, Partab Rai, Xiaoli Wang, Kan Sun

“…Significant differences were observed in mRNA and protein levels when compared with the NGT group, while methylation rates of eight CpG units within the FOSL2 gene were higher in the T2DM group. …”
Get full text

Impact of the COVID-19 Pandemic on Radiotherapy Supply by Francesco Tramacere, Artor Niccoli Asabella, Maurizio Portaluri, Corinna Altini, Cristina Ferrari, Lilia Bardoscia, Angela Sardaro

“…The COVID-19 pandemic affected the regular RT delivery to oncologic patients, owing to the delay or cancellation of procedures with the likely effect to observe worsening of local disease control and reduced survival rates in the future.…”
Get full text

Offshore Network Development to Foster the Energy Transition by Enrico Maria Carlini, Corrado Gadaleta, Michela Migliori, Francesca Longobardi, Gianfranco Luongo, Stefano Lauria, Marco Maccioni, Jacopo Dell’Olmo

“…A growing interest in offshore wind energy in the Mediterranean Sea has been recently observed thanks to the potential for scale-up and recent advances in floating technologies and dynamic cables: in the Italian panorama, the offshore wind connection requests to the National Transmission Grid (NTG) reached almost 84 GW at the end of September 2024. …”
Get full text

Abcb1 is involved in the efflux of trivalent inorganic arsenic from brain microvascular endothelial cells by Man Lv, Ziqiao Guan, Jia Cui, Xinbo Ma, Kunyu Zhang, Xinhua Shao, Meichen Zhang, Yanhui Gao, Yanmei Yang, Xiaona Liu

“…Increased arsenic levels were observed in mice exposed to 25 mg/L or 50 mg/L of sodium arsenite (NaAsO2) in drinking water, and both arsenic uptake and efflux were detected in bEnd.3 cells treated with 16 μmol/L NaAsO2. …”
Get full text