Image and Histologic Characterization of Intracranial Neoplasias by Martha Yudey Rodríguez Pino, Dianarelys Villafuerte Delgado, Thaimí Conde Cueto, Odalys Yanes Isray, Adelaida Martínez Godoy, Carlos Rafael Rivera Prieto

“…In 85, 7 % of the metastases a hypodense image was observed meanwhile in meningiomas a hyperdense image was seen. …”
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A Meta-Analysis and Systematic Review of the Efficacy of Twice Daily PPIs versus Once Daily for Treatment of Gastroesophageal Reflux Disease by Hongying Zhang, Zhiping Yang, Zhen Ni, Yongquan Shi

“…However, no significant differences were observed in heartburn relief (P=0.27), sustained symptom relief rates at week 4 (P=0.05), 24 h pH monitoring after treatment (P=0.11), endoscopic response at week 4 (P=0.22), and adverse events (P=0.18). …”
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Comparative efficacy of sleep positional therapy, oral appliance therapy, and CPAP in obstructive sleep apnea: a meta-analysis of mean changes in key outcomes by Yunjun Gao, Sixiang Zhu, Wenjun Li, Youqing Lai

“…Random-effects meta-analyses were conducted to compare mean changes between SPT and control groups (placebo, OAT, CPAP), with sensitivity analyses to assess heterogeneity.ResultsSleep positional therapy (SPT) showed a significant reduction in AHI in the supine position compared to placebo (MD = −7.46, 95% CI: −11.42, −3.49), although no difference was observed in overall AHI between SPT and placebo or OAT. …”
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WDRIV-Net: a weighted ensemble transfer learning to improve automatic type stratification of lumbar intervertebral disc bulge, prolapse, and herniation by Ichiro Nakamoto, Hua Chen, Rui Wang, Yan Guo, Wei Chen, Jie Feng, Jianfeng Wu

“…Furthermore, improved performance was observed as well for the metric of the area under the curve (AUC), producing a ≥ 7% increase versus other SOTA ensemble learning, a ≥ 6% increase versus most-studied models, and a ≥ 2% increase versus the baselines. …”
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QbD-Driven preparation, characterization, and pharmacokinetic investigation of daidzein-l oaded nano-cargos of hydroxyapatite by Namrata Gautam, Debopriya Dutta, Saurabh Mittal, Perwez Alam, Nasr A. Emad, Mohamed H. Al-Sabri, Suraj Pal Verma, Sushama Talegaonkar

“…A notable entrapment efficiency of 87.23 ± 0.97% and drug release of 91 ± 0.85% from DZHAPNPs was observed over 90 h at pH 7.4. Moreover, the XRD and FTIR results confirmed the amorphization and compatibility of DZHAPNPs. …”
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Assessment of the Momentum Balance Method for Determination of Shear Stress in Compound Meandering Channels by V. Moratzavi Amiri, K. Esmaili

“…The minimum amounts of shear stress were observed in section 5 in both RSM and MBM methods. …”
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Displacing the Christian Theodicy of Hell: Yi Kwangsu’s Search for the Willful Individual in Colonial Modernity by Jun-Hyeok Kwak, Mengxiao Huang

“…The Christian imaginary of hell in non-Western cultures often demarcates the question of God’s sovereignty from the sufferings of sinners in the problem of hell. Based on these observations, this article will investigate Yi’s narratives of hell in <i>The Heartless</i>, which are associated with Christianity but intertwined with his ethical demands for shaping a new individuality beyond the traditional hybrid religiosity of hell. …”
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The Roles of Autophagy, Mitophagy, and the Akt/mTOR Pathway in the Pathogenesis of Chronic Rhinosinusitis with Nasal Polyps by Chen Wang, Min-Li Zhou, Yong-Cai Liu, Ke-Jia Cheng

“…The downregulation of autophagy and mitophagy is also observed in eosinophilic and noneosinophilic nasal polyps. …”
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Effect of Myopic Femtosecond Laser-Assisted LASIK on Anterior Chamber Inflammation (Flare Values) and Corneal Endothelium: A Prospective before and after Study by Kemal Turgay Özbilen, Emre Altinkurt, Nihan Aksu Ceylan, Gizem Sayar Bilgin, Nilüfer Gözüm

“…A significant difference was observed only between the preoperative and postoperative 1st day flare values (p=0.047). …”
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Cuspal Displacement Induced by Bulk Fill Resin Composite Polymerization: Biomechanical Evaluation Using Fiber Bragg Grating Sensors by Alexandra Vinagre, João Ramos, Sofia Alves, Ana Messias, Nélia Alberto, Rogério Nogueira

“…A statistically significant correlation between cuspal deflection, time, and material was observed (p<0.01). Cuspal deflection reached 8.8 μm (0.23%) and 7.8 μm (0.20%) in Groups 1 and 2, respectively. …”
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The Mediation of Circulating Inflammatory Proteins in the Causal Pathway from Immune Cells to COPD by Yan K, Wang Y, Xin P

“…Kunrong Yan, Yingjian Wang, Peng Xin Department of Anaesthesia, Chaoyang Second Hospital, Chaoyang, Liaoning, People’s Republic of ChinaCorrespondence: Peng Xin, Email cy08xp@163.comObjective: Observational studies have indicated that immune cells and circulating inflammatory proteins may play a dual role in the progression of COPD; however, the precise mechanisms remain uncertain. …”
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Carbon Nanomaterials in the Treatment of Infectious Bone Defects and Wound Scars after Wushu Fractures by Shenghui Wei, Lei Zou, Xu Hu, Qiuming Li

“…Within 30 days after surgery, the appearance of the left hind limb wound and general signs of infection were closely monitored, body temperature was measured, and blood was collected from the ear veins of experimental animals to analyze the changes in C-reactive protein (CRP) and procalcitonin levels (PCT); X-ray, CT imaging, and histological observation were performed on 14 and 28 days. Studies have shown that when the drug loading of doxycycline increases from 10% to 15%, this is related to the change in properties of the polylactic acid fiber membrane from hydrophobic to hydrophilic caused by the increase in doxycycline drug loading.…”
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Application of Revised Universal Soil Loss Equation (Rusle) Model to Assess Soil Erosion in “Kalu Ganga” River Basin in Sri Lanka by D. L. D. Panditharathne, N. S. Abeysingha, K. G. S. Nirmanee, Ananda Mallawatantri

“…Use of the erosion severity information coupled with basin wide individual RUSLE parameters can help to design the appropriate land use management practices and improved management based on the observations to minimize soil erosion in the basin.…”
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Effectiveness of Tailored Multisensory Stimulation Intervention in People with Major Neurocognitive Disorder: A Quasiexperimental Pilot Study by Jèssica Garrido-Pedrosa, Elisabet Capdevila, Núria Berga-Quintana, Loreto González-Román, Maria Eulalia Guijosa-Mira, Irene Astilleros Castro, Jennifer Grau-Sánchez

“…Moreover, a substantial improvement in the participants’ quality of life, measured with the quality of life in Alzheimer’s disease (p=.03) and in neuropsychiatric symptoms (neuropsychiatric inventory-questionnaire, p=.04), was observed postintervention. Conclusion. MSS appears to be effective on mood and behaviour immediately after sessions and also appears to improve quality of life and reduce neuropsychiatric symptoms postintervention, when these are person-centred through one-to-one interventions that have been adapted to the participants’ sensory preferences.…”
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Orphan nuclear receptor NR2E3 is a new molecular vulnerability in solid tumors by activating p53 by Yidan Wang, Todd G. Kroll, Linhui Hao, Zhi Wen

“…Here, we demonstrate that the full-length protein isoform of NR2E3 instead of its short isoform activates wild-type p53 and is capable of rescuing certain p53 mutations in various cancer cell lines. Importantly, we observe a higher frequency of NR2E3 mutations in three solid tumors compared to the reference population, highlighting its potential significance in tumorigenesis. …”
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Serum Matrix Metalloproteinase 9 and Macrophage Migration Inhibitory Factor (MIF) Are Increased in Young Healthy Nonobese Subjects with Positive Family History of Type 2 Diabetes by Agnieszka Nikołajuk, Natalia Matulewicz, Magdalena Stefanowicz, Monika Karczewska-Kupczewska

“…An increased circulating level of proinflammatory proatherogenic factors and biomarkers of endothelial activation was observed in diabetes and CVD. The aim of our study was to assess serum proatherogenic and proinflammatory factors in young healthy nonobese subjects with positive family history of type 2 diabetes. …”
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The Long Noncoding RNA Gm9866/Nuclear Factor-κB Axis Promotes Macrophage Polarization by Xiaomin Liao, Xianxian Ruan, Xiubing Chen, Biaolin Zheng, Xianbin Wu, Zhejun Deng, Zhe Yang, Feng Wang, Shanyu Qin, Haixing Jiang

“…In this study, by conducting real-time polymerase chain reaction analysis, it was observed that long noncoding RNA Gm9866 expression significantly increased after treatment with interleukin-4 but significantly decreased after treatment with lipopolysaccharide. …”
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Topically Applied Connective Tissue Growth Factor/CCN2 Improves Diabetic Preclinical Cutaneous Wound Healing: Potential Role for CTGF in Human Diabetic Foot Ulcer Healing by F. R. Henshaw, P. Boughton, L. Lo, S. V. McLennan, S. M. Twigg

“…Wound healing rate was observed on day 14 and wound sites were examined for breaking strength and granulation tissue. …”
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Changes in physical characteristics of extreme rainfall events during the Indian summer monsoon based on downscaled and bias-corrected CMIP6 models by Stella Jes Varghese, Sreenivas Pentakota, Pushpalatha Thadivalasa, Gopikrishna Podapati, Karumuri Ashok

“…Abstract We identified a set of bias-corrected and downscaled Coupled Model Intercomparison Project 6 (CMIP6) models capable of accurately simulating the observed mean Indian summer monsoon rainfall, extreme rain events (EREs) and their respective interannual variability. …”
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Pengaruh Pemberian Mesenchymal Stem Cells Wharton's Jelly terhadap Ekspresi Gen Sirtuin 1 pada Tikus Model Alzheimer by Havina Nurul Aizah, Amel Yanis, Hirowati Ali, Tofrizal Tofrizal, Cimi Ilmiawati, Dessy Arisanty

“…It is found that people with Alzheimer's disease have a lower expression of Sirtuin-1 because of the oxidative stress that was produced by Aβ plaques. Objective: To observe the Sirtuin-1 gene in Alzheimer's disease rat models that AlCl3 was inducing after being given MSC-WJ. …”
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