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22341
Safety, Tolerability, and Pharmacokinetics of NIM‐1324 an Oral LANCL2 Agonist in a Randomized, Double‐Blind, Placebo‐Controlled Phase I Clinical Trial
Published 2025-01-01“…In conclusion, NIM‐1324 treatment is well‐tolerated up to daily oral doses of at least 1500 mg (nominal), a ≥ six‐fold margin over the anticipated therapeutic dose, and 1000 mg (maximum observed exposure), at least a four‐fold margin over the anticipated therapeutic dose with no dose limiting toxicities.…”
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22342
Monocarboxylate Transporters: Role and Regulation in Corneal Diabetes
Published 2022-01-01“…Changes appeared dependent on neuronal density, suggesting that MCTs are very likely critical to the neuronal defects observed in diabetic keratopathy/neuropathy. Further studies are warranted in order to fully delineate the role of MCTs in corneal diabetes.…”
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22343
Identification of subgroups of self-reported outcomes among breast cancer patients undergoing surgery and chemotherapy: A cross-sectional study
Published 2025-01-01“…Besides, significant differences in depression and sleep disorders were observed among the three groups. Conclusions: Breast cancer patients receiving surgery and chemotherapy can be divided into three subgroups. …”
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22344
FAKTOR MOTIVASI WISATAWAN NUSANTARA MILENIAL MENGINAP DI BOBOCABIN KINTAMANI
Published 2025-01-01“…Data collection techniques were carried out using observation, questionnaires, interviews, literature study, and documentation. …”
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22345
Comparative analysis of fodder legumes in Murmansk Province
Published 2022-12-01“…Weather conditions during the years of study differed in temperature and water regimes. Observations and records were made according to VIR’s guidelines. …”
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22346
Spontaneous Complete Regression of Colon Cancer Liver Metastases in a Lung Transplant Patient: A Case Report
Published 2023-01-01“…Unexpectedly, her clinical condition improved, and complete regression of liver metastases was observed on imaging two months later. Unfortunately, the patient developed rejection of her lung transplant and succumbed to pulmonary disease six months following her cancer diagnosis. …”
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22347
Assessment of ozone impact on forest vegetation using visible foliar injury, AOT40F exposure index and MDA concentration in two meteorologically contrasting years
Published 2025-01-01“…The correlation between AOT40F and visible injury was inconsistent; in 2021, minimal visible O3 injuries were observed, while these were more frequent in 2022, notably on Fagus sylvatica leaves. …”
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22348
KIDS CLUB: CHILD-FRIENDLY HOTEL MARKETING STRATEGY
Published 2025-01-01“…Data were collected by observation, in-depth interviews, questionnaire dissemination, literature studies, and documentation techniques. …”
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22349
Some issues of prosecutor’s participation in proceedings on administrative offences: based on the European Court of Human Rights case law
Published 2023-07-01“…However, the issues of human rights protection and observance of the principle of competition during the consideration of an administrative offence case remain unaddressed. …”
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22350
Effect of triage training on nurses with Emergency severity index and Australian triage scale: Α quasi-experimental study
Published 2024-10-01“…Additionally, statistically significant increases were observed for triage knowledge and for both screening scales that measured triage accuracy, namely the Emergency Severity Index (p < 0.001) and the Australian Triage Scale (p < 0.001). …”
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22351
La producción cinematográfica en la Argentina
Published 2014-06-01“…Pero también debe tenerse en cuenta la misma naturaleza de estas actividades, que se organizan por proyectos y en las cuales la empresa, como agente organizador de recursos, tiene un rol menor al observable en otras actividades económicas. Esto tiene consecuencias en términos de la calidad de la información estadística que se produce. …”
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22352
La géographie des élections en Algérie, de 2007 à 2017
Published 2024-07-01“…However, it remains interesting to analyse the electoral behavior of elections whose stake is not access to power, since we can observe a variety of forms of opposition to power or, conversely, better understand the networks on which power can rely. …”
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22353
Validation of <i>Monilinia fructicola</i> Putative Effector Genes in Different Host Peach (<i>Prunus persica</i>) Cultivars and Defense Response Investigation
Published 2025-01-01“…Although differences were observed among the fungal isolates, the principal component investigation identified the main differences linked to the host genotype. …”
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22354
An Enhanced End-to-End Object Detector for Drone Aerial Imagery
Published 2025-01-01“…DETR-like detectors have gained increasing popularity in current practical applications. However, we observe that their pipeline still suffer from several challenges, including unbalanced distribution of positive and negative samples, low-quality initial prediction boxes, and unreasonable gradient structure in the decoding stage. …”
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22355
The Wine Quality of Merlot Relies in Irrigation Supplementation and Spotlights Sustainable Production Constraints in Mediterranean-Type Ecosystems
Published 2024-01-01“…Integrating previously reported data, it is observed that water scarcity is favorable for quality only when compared with fully irrigated vineyards. …”
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22356
Análise da dinâmica temporal da cobertura vegetal na microrregião de Umarizal (2000 a 2022), semiárido do Rio Grande do Norte, Brasil
Published 2024-10-01“…After the analyses, it can be observed that SAVI values were higher in the rainy season, the year 2017 stood out for its low photosynthetic activity in both periods, due to the low levels of precipitation presented in the year in all municipalities in the micro-region. …”
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22357
Patient-reported outcomes of zirconia dental implants: a systematic review and future directions
Published 2025-01-01“…A high level of heterogeneity was observed among the instruments used for measuring the patient-reported outcomes in patients with zirconia implants, thus highlighting the need to develop specific PROMs in the future.…”
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22358
Long‐term follow‐up of intradetrusor botulinum toxin utilisation: A comparison of patients with multiple sclerosis and idiopathic overactive bladder
Published 2025-01-01“…Materials and Methods This is a retrospective, international, multi‐centre, observational cohort study of patients diagnosed with MS and neurogenic OAB and treated with intradetrusor BoNT between January 2005 and January 2020 (just prior to COVID‐19 interruption). …”
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22359
A comparative dataset on the GC–MS analysis and antioxidant activity of Selaginella bryopteris from different geolocations of IndiaMendeley Data
Published 2025-04-01“…A total of 12 and 14 peaks were observed in the chromatogram of methanolic extracts of plant from Karnataka (SBK) and Maharashtra (SBM), respectively. …”
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22360
Range of Motion and Muscle Stiffness Differences in Junior Tennis Players with and without a History of Shoulder Pain
Published 2025-01-01“… # Study Design Cross-sectional observational study. # Methods Twenty-five participants participated in the study (11 with a history of shoulder pain and 14 without pain). …”
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