The changing demographics and severity in hospitalized patients across COVID-19 variants: A national cohort study by Priyanka Parajuli, Lara A.C. Phipps, Roy Sabo, Rasha Alsaadawi, Amanda Robinson, Evan French, Richard K. Sterling, N3C. consortium

“…Conclusions: Despite changes in demographics over time, more recent COVID waves were associated with decreasing severity and mortality. These observations will help guide specific and effective resource allocation and patient care. …”
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Mapping the Structure-Function Relationship in Glaucoma and Healthy Patients Measured with Spectralis OCT and Humphrey Perimetry by Laia Jaumandreu, Francisco J. Muñoz–Negrete, Noelia Oblanca, Gema Rebolleda

“…The strongest correlation with visual fields was observed in the peripheral nasal region of both superior and inferior hemigrids (r=0.602 and r=0.458, resp.). …”
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Therapeutic Doses of Nonsteroidal Anti-Inflammatory Drugs Inhibit Osteosarcoma MG-63 Osteoblast-Like Cells Maturation, Viability, and Biomineralization Potential by E. De Luna-Bertos, J. Ramos-Torrecillas, O. García-Martínez, A. Guildford, M. Santin, C. Ruiz

“…However, nonsignificant differences were observed on collagen syntheses after treatments. The percentage of CD54 expression was increased with all treatments. …”
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Ionospheric Response to the Extreme 2024 Mother's Day Geomagnetic Storm Over the Latin American Sector by C. S. Carmo, L. Dai, C. M. Wrasse, D. Barros, H. Takahashi, C. A. O. B. Figueiredo, C. Wang, H. Li, Z. Liu

“…CHPI also features a Fabry‐Pérot interferometer (FPI) and an All‐Sky Imager (ASI). Super EPB was observed in the American sector. This structure drifted westward at a velocity of ∼140 m/s and had a large latitudinal extension, reaching about 36° geomagnetic latitude, this corresponds to an apex height of around 4,500 km. …”
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Implementation of the seven steps of patient safety in primary healthcare by Nur Syarianingsih Syam, Linda Tri Maryuni, Siti Kurnia Widi Hastututi, Sely Aprianda Syah Putri

“…Data collection techniques used include field observations, interviews, and document review. The results showed that one of the primary health care facilities in Yogyakarta City has implemented seven patient safety steps. …”
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Targeting Caveolin‐1 in Multiple Myeloma Cells Enhances Chemotherapy and Natural Killer Cell‐Mediated Immunotherapy by Dewen Zhan, Zhimin Du, Shang Zhang, Juanru Huang, Jian Zhang, Hui Zhang, Zhongrui Liu, Eline Menu, Jinheng Wang

“…As a result of CAV1 inhibition, MM cells are more sensitive to starvation, glutamine depletion, and glutamine transporter inhibition, and grow more slowly in vivo in a mouse model treated with bortezomib. The observation that CAV1 inhibition modulated by 6‐mercaptopurine, daidzin, and statins enhances the efficacy of bortezomib in vitro and in vivo highlights the translational significance of these FDA‐approved drugs in improving MM outcomes. …”
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Microscale Research on Effective Geosequestration of CO2 in Coal Reservoir: A Natural Analogue Study in Haishiwan Coalfield, China by Kaizhong Zhang, Wei Li, Yuanping Cheng, Jun Dong, Qingyi Tu, Rong Zhang

“…Simultaneously, coal and oil shale samples before and after supercritical CO2 (SCCO2) treatment via geochemical reactor were collected to analyze changes in pore structure, functional group distributions, and SCCO2 extraction. Observations from in situ properties of coal seam indicate that there is a positive relationship with CH4 contents and F19 fault whereas CO2 and carbonate contents decrease as the distance from F19 increases. …”
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Spatiotemporal evolution of ecological vulnerability on the Loess Plateau by Xianqi Zhang, Yupeng Zheng, Yang Yang, He Ren, Jiawen Liu

“…Significant spatial variation was observed, with the highest levels of ecological vulnerability concentrated in Inner Mongolia, northern Shaanxi, Ningxia Hui, and Gansu provinces. …”
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Study on Creep Characteristics of Expansive Soil in High-Fill Channel of South-to-North Water Transfer Project by Jianhua Guo, Zhangjun Dai, Shichang Li, Nadeem Muhammad, Hui Gao

“…Moreover, it is also observed that the secondary consolidation coefficient of unsaturated expansive soil increases with the increase of moisture content and decreases with the increase of dry density. …”
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Pulsed GMAW-based WAAM–Influence of droplet detachment mode on the geometry and mechanical properties of 308 L stainless steel by R.F. Rezende, A.R. Arias, E.J. Lima, II, F.G.F. Coelho

“…A greater heat input was observed in the ODMP mode. The MDPP and ODPP modes produced thinner preforms with a better surface finish. …”
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Vitamin D Receptor Polymorphisms Predispose to Primary Biliary Cirrhosis and Severity of the Disease in Polish Population by Agnieszka Kempińska-Podhorecka, Ewa Wunsch, Tomasz Jarowicz, Joanna Raszeja-Wyszomirska, Beata Loniewska, Mariusz Kaczmarczyk, Małgorzata Milkiewicz, Piotr Milkiewicz

“…When compared to controls, we observed a significant dominance of the b allele in the BsmI (OR = 1.69 [1.27–2.24]; P=0.0003) and t allele in the TaqI (OR = 0.62 [0.47–0.82], P=0.0001) in patients with PBC. …”
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Study of the application prospects of film detectors for estimation of α-radiation density by Dana S. Yerimbetova, Marina Konuhova, Artem L. Kozlovskiy, Umitali N. Tuichiyev

“…It was determined that the most significant changes are observed at densities of registered α-particles above 104 cm−2, the value of which is the threshold value for identification of radon decay products using film detectors without chemical etching.…”
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The Phenox Clot Retriever as Part of a Multimodal Mechanical Thrombectomy Approach in Acute Ischemic Stroke: Single Center Experience in 56 Patients by Sascha Prothmann, Hannah Lockau, Franziska Dorn, Holger Poppert, Annette Förschler, Claus Zimmer, Thomas Liebig

“…A chronological analysis showed a reduction of ART from 70,5 to 49,4 minutes and an increase of TICI 2b/3 recanalizations from 53,8% to 81,8%. Throughout the observation period there was a significant shift towards multimodal procedures with simultaneous increase of TICI 2b/3 reperfusions. …”
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Higher levels of oxidative balance score linked to lower risk of gallstones: findings from the 2017–2020 National Health and Nutrition Examination Survey by Ting Xiong, Ting Xiong, Ting Xiong, Zhonghuo Chen, Zhonghuo Chen, Zhonghuo Chen, Jianwei Yi, Jianwei Yi, Jianwei Yi, Taozhi Yu, Taozhi Yu, Taozhi Yu, Kai Wang, Kai Wang, Kai Wang, Kai Wang

“…After adjusting for confounding factors, a significant negative association was observed between OBS and gallstone prevalence (quartile 4 vs. quartile 1: odds ratio [OR] 0.63, 95% confidence interval [CI] 0.43–0.90, p = 0.019). …”
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Research note: Whole-genome sequencing revealed genomic diversity dynamics in duck conserved populations by Yu-Ze Yang, Zhong-Tao Yin, Xiao-Ran Lin, Chun-Ying Zhao, Fang-Xi Yang, Fei-Fan Chen, Zhuo-Cheng Hou

“…Both the expected heterozygosity and observed heterozygosity values exceeded 0.3. The genetic differentiation (FST) values ranged from 0.007 to 0.039, and the Polymorphism information content (PIC) values ranged from 0.29 to 0.34. …”
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The Causative Pathogen Determines the Inflammatory Profile in Cerebrospinal Fluid and Outcome in Patients with Bacterial Meningitis by Denis Grandgirard, Rahel Gäumann, Boubacar Coulibaly, Jean-Pierre Dangy, Ali Sie, Thomas Junghanss, Hans Schudel, Gerd Pluschke, Stephen L. Leib

“…To elucidate the pathomechanisms behind the observed difference in outcome between different pathogens, we compared the inflammatory profile in the CSF of patients with BM caused by Streptococcus pneumonia (n=14), Neisseria meningitidis (n=22), and Haemophilus influenza (n=9). …”
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Local Overexpression of Interleukin-11 in the Central Nervous System Limits Demyelination and Enhances Remyelination by Anurag Maheshwari, Kris Janssens, Jeroen Bogie, Chris Van Den Haute, Tom Struys, Ivo Lambrichts, Veerle Baekelandt, Piet Stinissen, Jerome J. A. Hendriks, Helena Slaets, Niels Hellings

“…When IL-11 expressing LV was therapeutically applied in animals with extensive demyelination, a significant enhancement of remyelination was observed as demonstrated by Luxol Fast Blue staining and electron microscopy imaging. …”
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Evaluation of Tele-rheumatology during the COVID-19 Pandemic in Asian Population: A Pilot Study by Amit Sandhu, Amit Agarwal, Paramvir Kaur, Meenakshi Sharma, Harnoor Sra, Manvi Singh, Nishant Jaiswal, Anil Chauhan, Anju Gupta, Meenu Singh

“…Saving of time and money was observed as beneficial factors for patients. More than three-quarters of all rheumatoid arthritis patients were ready to use teleconsultation in the near future. …”
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Influence of the Culture Medium in Dose-Response Effect of the Chlorhexidine on Streptococcus mutans Biofilms by Vanessa Salvadego de Queiroz, Renzo Alberto Ccahuana-Vásquez, Alcides Fabiano Tedesco, Luzia Lyra, Jaime Aparecido Cury, Angélica Zaninelli Schreiber

“…Results showed CHX dose-response effect being observed in all media for all the variables. However, MH and MHS showed higher sensitivity than UTYEB (p<0.05). …”
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Shoot Organogenesis and Plant Regeneration from Leaf Explants of Lysionotus serratus D. Don by Qiansheng Li, Min Deng, Jie Zhang, Wei Zhao, Yigang Song, Quanjian Li, Qingjun Huang

“…High BA concentration (1.0 mg L−1) in the media caused high percentage of vitrified shoots though they introduced high shoot proliferation rate. Histological observation indicated that adventitious shoot regeneration on the medium containing 0.5 mg L−1 BA alone occurred directly from leaf epidermal cells without callus formation. …”
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