Targeting lipid metabolism: novel insights and therapeutic advances in pancreatic cancer treatment by Yanyan Zhang, Zhichao Yang, Yuchen Liu, Jinjin Pei, Ruojie Li, Yanhui Yang

“…Dysregulation of cholesterol biosynthesis and alterations in fatty acids (FAs), such as palmitate, stearate, omega-3, and omega-6, have been observed in pancreatic cancer. These lipids serve as energy sources, signaling molecules, and essential components of cell membranes. …”
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Overweight or Obese Individuals at Eighteen Years of Age Develop Pancreatic Adenocarcinoma at a Significantly Earlier Age by David T. Chao, Nilesh H. Shah, Herbert J. Zeh, Aatur D. Singhi, Nathan Bahary, Kevin M. McGrath, Kenneth E. Fasanella, Amer H. Zureikat, David C. Whitcomb, Randall E. Brand

“…No significant difference was observed in the mean age of PC diagnosis in those patients who maintained a normal BMI-18 when compared to those patients who subsequently became overweight or obese (67.0 versus 66.6; p=0.65). …”
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Effects of Elevated Ambient Temperature on Reproductive Outcomes and Offspring Growth Depend on Exposure Time by Huda Yahia Hamid, Md Zuki Abu Bakar Zakaria, Goh Yong Meng, Abd. Wahid Haron, Noordin Mohamed Mustapha

“…However, no significant differences were observed between groups 1 and 2 in the gestation length, sex ratios, and growth patterns. …”
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Methylenetetrahydrofolate reductase gene polymorphisms, lipid profiles, and basic renal functional markers as risk for myocardial infarction: A case-control study and haplotype ana... by Perović Svetlana, Vujović Slavica, Kapur-Pojskić Lejla, Garai Nemanja, Šćepanović Anđelka

“…A similar association was observed for the C677T polymorphism (P=0.003). An A-T haplotype represented an increased risk for MI (OR=1.630; P=0.014), whereas the A-C haplotype had a protective role (R=0.517; P=0.002). …”
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Transanal endoscopic cooperative surgery as a less invasive resection technique for anorectal tumors extending beyond the dentate line: Case series by Kohei Shigeta, Kazunori Takada, Kinichi Hotta, Kenichiro Imai, Sayo Ito, Junya Sato, Yoichi Yamamoto, Masao Yoshida, Yuki Maeda, Noboru Kawata, Hirotoshi Ishiwatari, Hiroyuki Matsubayashi, Akio Shiomi, Hiroyasu Kagawa, Manabe Shoichi, Yusuke Yamaoka, Shunsuke Kasai, Yusuke Tanaka, Yasuyuki Hirashima, Ayako Mochizuki, Shusuke Yoshikawa, Arata Tsutsumida, Wataru Omata, Takuma Oishi, Hiroyuki Ono

“…A postoperative abscess around the anastomosis was observed in one case. The anal sphincter was preserved in all cases. …”
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Effect of Iota-Carrageenan and Its Hydrolysates on the Stability of Milk Ice Cream Mixes by Anna Kot, Ewa Jakubczyk, Magdalena Buniowska-Olejnik, Anna Kamińska-Dwórznicka

“…The sedimentation, coalescence and flocculation were observed based on the backscattering profile and CLSM images. …”
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Nanomechanical Characterization of Canine Femur Bone for Strain Rate Sensitivity in the Quasistatic Range under Dry versus Wet Conditions by Kun-Lin Lee, Marta Baldassarri, Nikhil Gupta, Dinesh Pinisetty, Malvin N. Janal, Nick Tovar, Paulo G. Coelho

“…No influence of the loading/unloading rates was observed between groups except for the elastic modulus measured at 1000 μN/s rate under dry conditions (P<0.001) and for the hardness measured at a rate of 10 μN/s under wet conditions (P<0.001). …”
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Determining Proportion of Exfoliative Vaginal Cell during Various Stages of Estrus Cycle Using Vaginal Cytology Techniques in Aceh Cattle by Tongku N. Siregar, Juli Melia, Rohaya, Cut Nila Thasmi, Dian Masyitha, Sri Wahyuni, Juliana Rosa, Nurhafni, Budianto Panjaitan, Herrialfian

“…A vaginal swab was collected from aceh cattle, stained with Giemsa 10%, and observed microscopically. Period of estrus cycle was predicted from day 1 to day 24 after estrus synchronization was confirmed using ultrasonography analysis at the same day. …”
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Determinants of adherence to the Mediterranean diet among individuals with type 2 diabetes mellitus living in Mediterranean countries: a systematic review by Janot J. Ayoub, Janot J. Ayoub, Suzan A. Haidar, Ellen E. Blaak, Nanne K. De Vries

“…An increased shift toward a “Western” dietary pattern was observed.ObjectiveThis systematic review aims to gain insight into the various factors that may enhance or reduce adherence to the MD in patients with T2DM residing in Mediterranean countries.MethodWe retrieved published studies from 2000 to 2023 from PubMed, Cochrane, Embase, CINAHL, Web of Science, Medline, and PsycINFO databases. …”
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Comparison of lignin degradation and flavor compound formation in roasted tobacco by two Bacillus subtilis strains by Junmin Wang, Teng Long, Zhenkun Jiang, Wenjun Mu, Mingliang Su, Li Ni, Shunhua Ji, Yuqing Wang, Kangxi Zhou, Renfeng Zhan, Lixuan Nie, Jingjing Li, Xingchuan Hu, Wei He, Wen Zhang

“…A notable distinction was observed in the organoleptic evaluation and volatile flavor compounds, as determined by sensory evaluation and GC–MS analysis. …”
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Chronic Mild Stress Modulates Activity-Dependent Transcription of BDNF in Rat Hippocampal Slices by Raffaella Molteni, Andrea C. Rossetti, Elisa Savino, Giorgio Racagni, Francesca Calabrese

“…This different effect was also observed in the activation of intracellular signaling pathways related to the neurotrophin. …”
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Assessment of Tear Film Quality among Smokers Using Tear Ferning Patterns by Ali M. Masmali, Adil Al-Shehri, Saud A. Alanazi, Ali Abusharaha, Raied Fagehi, Gamal A. El-Hiti

“…Tear samples were collected from the right eyes and tear ferning patterns were observed and graded. Results. The mean MacMonnies scores and TF grades were significantly higher in the smoker subjects (mean ± SD = 9.83±5.22 and 0.96±0.54, resp.) compared to nonsmokers (mean ± SD = 5.96±3.06 and 0.41±0.38, resp.). …”
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Evaluating the Real-World Effectiveness of Systemic Treatments in Atopic Dermatitis Using the Atopic Dermatitis Control Tool (ADCT): A Multi-Centre, Prospective Study by Hyun Ji Lee, Yuri Woo, Young Bok Lee, Ji Hye Lee, Jung Eun Kim, Ji Hyun Lee, Sang Hyun Cho

“…To evaluate the effectiveness of the Atopic Dermatitis Control Tool (ADCT) in assessing disease severity in patients with moderate to severe atopic dermatitis and to compare the efficacy of systemic immunosuppressants and dupilumab in patients with moderate to severe atopic dermatitis. A prospective, observational study was conducted across seven centres in Korea, involving 112 patients with moderate to severe atopic dermatitis. …”
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Exploring the Gating Mechanism of the Human Copper Transporter, hCtr1, Using EPR Spectroscopy by Shahaf Peleg, Shelly Meron, Yulia Shenberger, Lukas Hofmann, Lada Gevorkyan-Airapetov, Sharon Ruthstein

“…Moreover, this phenomenon was observed for both reconstituted protein in micelles and in native cell membranes. …”
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Overexpression of NtCET4 gene in tobacco promoted vegetative bud activity and delayed flowering by LONG Junlan, LUO Rui, LUO Xu, ZHANG Lan

“…The overexpressed plants were transplanted into fields to observe flowering time and leaf numbers. qRTPCR was used to identify relative expressions of NtCET4 before and after flowering. …”
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Correction of cellular and humoral links immunity in piglets under the weaning condition by Nataliia Ohorodnyk, Vitalii Tkachuk, Nataliia Motko, Andriy Boyko, Serhii Pavkovych

“…Conversely, the administration of the liposomal preparation to piglets enhanced the number of various subpopulations of total and active T-lymphocytes and B-lymphocytes in their blood after weaning and increased the activity of lymphoid cells in the blast transformation reaction with phytohaemagglutinin. The observed immunomodulatory effect of the tested drug is attributed to the synergistic combination of fat-soluble vitamins, mineral elements, and arginine in its composition, which effectively prevented the development of stress-induced immunodeficiency in piglets following weaning…”
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Cerebral Hemodynamics and Cognitive Function in Cirrhotic Patients with Hepatic Encephalopathy by Yuqing Zhou, Qian Dong, Rong Zhang, Shunfeng Zhou, Linqiang Li, Keran Cheng, Rui Kong, Qiang Yu, Shizan Xu, Jingjing Li, Sainan Li, Jiao Feng, Liwei Wu, Tong Liu, Xiya Lu, Kan Chen, Yujing Xia, Jie Lu, Yingqun Zhou, Chuanyong Guo

“…To investigate cerebral hemodynamics in cirrhotic patients with HE and to observe effects of treatment in cerebral hemodynamics and correlations among ammonia, cerebral hemodynamics, and cognitive function. …”
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In Vivo Healing Potential of Aegle marmelos in Excision, Incision, and Dead Space Wound Models by M. K. Gautam, V. Purohit, M. Agarwal, A. Singh, R. K. Goel

“…Complete wound contraction and epithelization were observed at the 20th day after treatment with AME as compared to the 24th day in control rats. …”
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A Hybrid FEM-CNN for Image-Based Severity Prediction of Corroded Offshore Pipelines by Mohammad Fadzil Najwa, Muda Mohd Fakri, Abdul Shahid Muhammad Daniel, Aziz Norheliena, Mohd Mohd Hairil, Mohd Amin Norliyati, Mohd Hashim Mohd Hisbany

“…An exceptional predictive accuracy was observed, attaining average confidence levels between 97% and 100%. …”
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Magnetic susceptibility components reveal different aspects of neurodegeneration in alpha-synucleinopathies by Oliver C. Kiersnowski, Pietro Mattioli, Lucia Argenti, Laura Avanzino, Francesco Calizzano, Andrea Diociasi, Laura Falcitano, Chunlei Liu, Mattia Losa, Federico Massa, Silvia Morbelli, Beatrice Orso, Elisa Pelosin, Stefano Raffa, Matteo Pardini, Dario Arnaldi, Luca Roccatagliata, Mauro Costagli

“…Correlations of putamen and caudate SBR Z-scores with PCS and DCS in the substantia nigra, putamen, and caudate were investigated. Increased PCS was observed in the substantia nigra of prodromal alpha-synucleinopathy patients with positive DaT-SPECT compared to controls and prodromal patients with negative DaT-SPECT. …”
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