TSH Levels in Subclinical Hypothyroidism in the 97.5th Percentile of the Population by Laura Pérez-Campos Mayoral, María Teresa Hernández-Huerta, Gabriel Mayoral-Andrade, Eduardo Pérez-Campos Mayoral, Edgar Zenteno, Ruth Martínez-Cruz, Héctor Martínez Ruíz, Margarito Martínez Cruz, Alma Dolores Pérez Santiago, Eduardo Pérez-Campos

“…We have written a selective nonsystematic review focused on the 97.5 percentile reference value reported in healthy subjects in a number of countries and observed important disparities, which partly show the challenge of identifying a single cutoff point for those patients needing medication. …”
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Clinical Behavior of Bladder Urothelial Carcinoma in Young Patients: A Single Center Experience by Volkan Sen, Ozan Bozkurt, Omer Demir, Ahmet Adil Esen, Ugur Mungan, Guven Aslan, Aykut Kefi, Ilhan Celebi

“…Recurrence was detected in 14/39 (35.9%) patients but progression was not observed in any patients. The mean age of recurrent patients was significantly higher than nonrecurrent patients (34.8 versus 28.5 years; p<0.05). …”
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Influence of Relative Humidity and Aging on Morphology and Chemical Composition on Biomass Burning Particle by Titinan Utavong, Thunyapat Thongyen, Surat Bualert, Parkpoom Choomanee, Saranarat Kongkeaw, Tanawan Rattanapotanan, Jitlada Phupijit, Suteekan Maneejantra, Nitchakarn Changplaiy

“…Under high RH condition (90%), the FPM had a larger GMDN and a significant influence on its morphology, as observed in coated spherical or agglomerated shapes. …”
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Digestive Enzyme Inhibition of Different Phenolic Fractions and Main Phenolic Compounds of Ultra-High-Pressure-Treated Palm Fruits: Interaction and Molecular Docking Analyses by Qingfeng Zhou, Jiexin Zhou, Xiaojing Liu, Yan-Bing Zhang, Shengbao Cai

“…Catechin and caffeic acid, main phenolic compounds detected in all phenolic fractions of the fruits, showed similar efficiencies on inhibiting the two enzymes, which were consistent with the findings observed by molecular docking analysis. Moreover, these two phenolic compounds exhibited a synergy effect on inhibiting pancreatic lipase and α-glucosidase at a relatively high combination concentration with the ratio of 1 : 1. …”
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Comparative Cranial Joint Variation in Three Different Lizards: Impact of Feeding Habit by Elif Yıldırım Caynak, Kamil Candan, Yusuf Kumlutaş, Ahmet Gökay Korkmaz, Sezen Birlik, Dudu Mertgenç Yoldaş, Serkan Gül, Çetin Ilgaz

“…Different cranial joints permitting intracranial mobility have been observed among these species using histological section and whole-mount techniques. …”
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Nursing of a patient undergoing transcatheter aortic valve implantation for aortic valve stenosis and lower limb artery occlusion (1例主动脉瓣狭窄合并下肢动脉闭塞患者经导管主动脉瓣置换术的护理)... by SI Shanshan (斯珊珊)

“…Based on the establishment of nurse-led multidisciplinary team as a comprehensive nursing intervention chain, efforts were made to enhance the management of heart failure, hemodialysis management, gangrene wound nursing, complications observation and psychological nursing for the patient. …”
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Comparative transcriptomic and phenotypic analysis of monoclonal and polyclonal Populus deltoides genotypes by Macy Gosselaar, Macy Gosselaar, Mark A. Arick, Chuan-Yu Hsu, Heidi Renninger, Courtney M. Siegert, Waqar Shafqat, Daniel G. Peterson, Austin Himes

“…RNA sequencing revealed upregulation of key genes such as exocyst subunit exo70 family protein H7 (EXO70H7), NDH-dependent cyclic electron flow 5 (NDF5), and expansin-like A3 (EXLA3). We also observed enrichment in phenylalanine metabolism and other secondary metabolic pathways in clone S7C8. …”
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Midkine Is a Novel Regulator of Amphetamine-Induced Striatal Gliosis and Cognitive Impairment: Evidence for a Stimulus-Dependent Regulation of Neuroinflammation by Midkine by Marta Vicente-Rodríguez, Rosalía Fernández-Calle, Esther Gramage, Carmen Pérez-García, María P. Ramos, Gonzalo Herradón

“…Significant deficits in the Y-maze test were only observed in amphetamine-pretreated MK−/− mice. The data demonstrate for the first time that MK is a novel modulator of neuroinflammation depending on the inflammatory stimulus and the brain area considered. …”
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Assessing moisture content in XLPE power cables using frequency-dependent tangent delta measurements by Babu Naik Gugulothu, Sanjay Lakshminarayanan, Madhu Palati, Suresh Haleyur Lakshmegowda, Mahipal Bukya

“…We conduct an experiment to estimate the moisture content and observe satisfactory agreement between the experimental and theoretical values. …”
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Impact of the −174 G > C IL-6 Polymorphism on Bioelectrical Parameters in Obese Subjects after Laparoscopic Adjustable Gastric Banding by Laura Di Renzo, Maria Grazia Carbonelli, Alessia Bianchi, Emidio Domino, Maria Rita Migliore, Guido Rillo, Leonardo Iacopino, Nicola Di Daniele, Antonino De Lorenzo

“…Significant higher reductions in BMI and Xc/H were observed in C(+) with respect to C(−) carriers. Conclusions. …”
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TNF-α Regulates Natriuretic Peptides and Aquaporins in Human Bronchial Epithelial Cells BEAS-2B by Letizia Mezzasoma, Lucio Cagini, Cinzia Antognelli, Francesco Puma, Eugenio Pacifico, Vincenzo Nicola Talesa

“…In particular, we found that TNF-α induced a decrease of arial natriuretic peptide, natriuretic peptide receptor-1, aquaporin-1 and aquaporin-5 and an increase of brain natriuretic peptide with a different involvement of nuclear factor-κB and mitogen-activated protein kinases signaling pathway activation. Moreover, the observed changes in NPs expression, demonstrate inflammation as an additional cause of brain natriuretic peptide elevation, adding an important piece of information in the novel area of study regarding NPs and inflammation. …”
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Circulating IL-1β, IL-17, and IP-10 as Potential Predictors of Hepatitis B Virus Infection Prognosis by Zhenzhen Su, Jie Chen, Junlong Zhang, Yunfei An, Yun Liao, Xiaojuan Wu, Chuanmin Tao, Lanlan Wang, Bei Cai

“…Furthermore, positive correlations of IP-10 with alanine aminotransferase and aspartate aminotransferase levels were observed (rs=0.546 and 0.644, respectively; P<0.001). …”
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Quadruple Therapy Offers High SVR Rates in Patients with HCV Genotype 4 with Previous Treatment Failure by Yousry Esam-Eldin Abo-amer, Rehab Badawi, Mohamed El-Abgeegy, Heba Fadl Elsergany, Ahmed Abdelhaleem Mohamed, Sahar Mohamed Mostafa, Hatem Samir Alegaily, Shaimaa Soliman, Sally Elnawasany, Sherief Abd-Elsalam

“…The primary aim of the study was to assess the efficacy and safety of a quadruple regimen of (sofosbuvir, daclatasvir, and simeprevir with a weight-based ribavirin) in chronic HCV DAAs-experienced patients. Methods. This observational, open-label prospective study was carried out on 103 genotype 4 hepatitis C virus-infected patients who failed to achieve SVR12 after sofosbuvir-daclatasvir with or without ribavirin. …”
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Regular Consumption of a Flavanol-rich Chocolate can Improve Oxidant Stress in Young Soccer Players by Cesar G. Fraga, Lucas Actis-Goretta, Javier I. Ottaviani, Fernando Carrasquedo, Silvina B. Lotito, Sheryl Lazarus, Harold H. Schmitz, Carl L. Keen

“…No changes in the plasma levels of (-)-epicatechin were observed following analysis of fasting blood samples. …”
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Pathogenic and periodontal bacteria may contribute to the fatal outcome of critically ill elderly COVID-19 patients by L. Johana Madroñero, Eliana P. Calvo, Carolina Coronel-Ruiz, Myriam L. Velandia-Romero, María Angélica Calderón-Peláez, Jhann A. Arturo, Adriana P. Franco-Rodríguez, Ricardo Gutiérrez-Pérez, Lady S. López, Félix G. Delgado, Sigrid J. Camacho-Ortega, Lilia J. Bernal-Cepeda, Sonia P. Bohórquez, Jaime E. Castellanos

“…Elevated levels of blood urea nitrogen, creatinine and lactate dehydrogenase, and higher frequencies of cardiovascular disease, diabetes mellitus and renal disease were observed in patients with a fatal outcome. Compared to patients who recovered from COVID-19, patients who died exhibited a microbiome enriched in periodontal and pathogenic bacteria such as Klebsiella pneumoniae. …”
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Analysis of Heat Transfer Performance Impact for Passive Containment Air-Cooling System Radiation Plates by Hongliang Wang, Yu Feng, Mingrui Yu, Yong Guo, Wei Li, Qiang Guo, Yidan Yuan

“…Specifically, when a radiation plate is positioned 0.9 m from the inner wall of the concrete shell, an improvement in PAS heat transfer power by as much as 34.4% can be achieved. However, it was observed that increasing the number of radiation plates has a minimal impact on overall performance; thus, utilizing multiple plates does not further augment the PAS heat transfer capability. …”
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ZBP1-mediated PANoptosis is a crucial lethal form in diverse keratinocyte death modalities in UVB-induced skin injury by Xuechan Bi, Min Li, Yiming Guo, Mengyao Hu, Yujie Chen, Ni Lian, Sihan Chen, Min Li, Heng Gu, Xu Chen

“…Recently, the pattern of coexistence of pyroptosis, apoptosis, and necroptosis has been termed PANoptosis; however, whether PANoptosis occurs in keratinocytes in UVB-induced skin injury remains unclear. We observed that the key molecules of GSDMD-mediated pyroptosis, apoptosis, and necroptosis, which are N-terminal GSDMD, cleaved caspase-3/PARP, and phosphorylated MLKL, respectively, were elevated in keratinocytes of UVB-challenged mice and human skin tissue. …”
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Inhibition of Notch Signaling Promotes the Differentiation of Epicardial Progenitor Cells into Adipocytes by Bin Liu, Dinghui Wang, Tianhua Xiong, Yajie Liu, Xiaodong Jing, Jianlin Du, Qiang She

“…Frozen sections of C57BL/6J mouse hearts were used to observe epicardial adipose tissue (EAT), and genetic lineage methods were used to trace EPCs. …”
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Vitamin D Status and VDR Genotype in NF1 Patients: A Case-Control Study from Southern Brazil by Larissa Souza Mario Bueno, Clévia Rosset, Ernestina Aguiar, Fernando de Souza Pereira, Patrícia Izetti Ribeiro, Rosana Scalco, Camila Matzenbacher Bittar, Cristina Brinckmann Oliveira Netto, Guilherme Gischkow Rucatti, José Artur Chies, Suzi Alves Camey, Patricia Ashton-Prolla

“…Genotypic and allelic frequencies of VDR gene polymorphisms were obtained from the same NF1 patients and 150 healthy controls. 25(OH)D deficiency or insufficiency was not more frequent in NF1 patients than in controls (p=0.074). We also did not observe an association between FokI and BsmI VDR gene polymorphisms and vitamin D levels in NF1 patients, suggesting that their deficient or insufficient biochemical phenotypes are not associated with these genetic variants. …”
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Advancing ex vivo functional whole-organ prostate gland model for regeneration and drug screening by Karthikeyan Subbiahanadar Chelladurai, Jackson Durairaj Selvan Christyraj, Kamarajan Rajagopalan, Johnson Retnaraj Samuel Selvan Christyraj

“…We successfully maintained the earthworm prostate gland in cell culture media for over 200 days, with observed beating behavior confirming its viability. …”
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