A Randomized Controlled Trial of Chinese Medicine on Nonmotor Symptoms in Parkinson’s Disease by Ka-Kit Chua, Adrian Wong, Kam-Wa Chan, Yin-Kei Lau, Zhao-Xiang Bian, Jia-Hong Lu, Liang-Feng Liu, Lei-Lei Chen, Ka-Ho Chan, Kim-Pong Tse, Anne Chan, Ju-Xian Song, Justin Wu, Li-Xing Zhu, Vincent Mok, Min Li

“…Outcome measures were baseline to week 32 changes in Movement Disorder Society-Sponsored Revision of Unified PD Rating Scale (MDS-UPDRS) Parts I–IV and in NMS assessment scale for PD (NMSS). We observed improvements in the NMSS total score (p=0.019), mood/cognition (p=0.005), and reduction in hallucinations (p=0.024). …”
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Association Analysis of NALCN Polymorphisms rs1338041 and rs61973742 in a Chinese Population with Isolated Cervical Dystonia by Qingqing Zhou, Jing Yang, Bei Cao, Yongping Chen, Qianqian Wei, Ruwei Ou, Wei Song, Bi Zhao, Ying Wu, Huifang Shang

“…No significant differences were observed in either the genotype distributions or the minor allele frequencies (MAFs) of the two SNPs between the CD patients and the HCs. …”
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Effect of Antihypertensive Therapy on SCORE-Estimated Total Cardiovascular Risk: Results from an Open-Label, Multinational Investigation—The POWER Survey by Guy De Backer, Robert J. Petrella, Assen R. Goudev, Ghazi Ahmad Radaideh, Andrzej Rynkiewicz, Atul Pathak

“…Design & Methods. The Physicians' Observational Work on patient Education according to their vascular Risk (POWER) survey was an open-label investigation of eprosartan-based therapy (EBT) for control of high blood pressure in primary care centers in 16 countries. …”
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Prolactin Levels Correlate with Abnormal B Cell Maturation in MRL and MRL/lpr Mouse Models of Systemic Lupus Erythematosus-Like Disease by Maria Victoria Legorreta-Haquet, Rocio Flores-Fernández, Francisco Blanco-Favela, Ezequiel M Fuentes-Pananá, Luis Chávez-Sánchez, Rafael Hernández-González, Emiliano Tesoro-Cruz, Lourdes Arriaga-Pizano, Adriana Karina Chávez-Rueda

“…In this study, our aims were to determine the level of PRL receptor expression during bone-marrow B-cell development and to assess whether the presence of high PRL serum concentrations influences absolute numbers of developing populations and disease outcome in lupus-prone murine models. We observed that the PRL-receptor is expressed in early bone-marrow B-cell; the expression in lupus-prone mice, which had the highest level of expression in pro-B cells and immature cells, differed from that in wild-type mice. …”
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Human Mature Adipocytes Express Albumin and This Expression Is Not Regulated by Inflammation by Maria Luisa Sirico, Bruna Guida, Alfredo Procino, Andrea Pota, Maurizio Sodo, Giuseppe Grandaliano, Simona Simone, Giovanni Pertosa, Eleonora Riccio, Bruno Memoli

“…A significant negative correlation was observed between albumin levels and fat mass in both healthy subjects and inflamed ESRD patients. …”
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Chemical, Physical, and Sensory Properties of Bread with Popped Amaranth Flour by Guadalupe Chaquilla-Quilca, Alma Rosa Islas-Rubio, Francisco Vásquez-Lara, Lourdes Salcedo-Sucasaca, Reynaldo Justino Silva-Paz, Jesús Guadalupe Luna-Valdez

“…A significant increase in contents of protein (around 12%) and raw fiber (more than 100%), and a decrease in carbohydrate content (around 6%) in breads at the highest substitution level compared to wheat bread were observed. At this substitution level, the RVA profile parameters, specific volume, pore area, and colour coordinates ( L *, a *, and b *) differed significantly. …”
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Structural and vascular assessment of the optic nerve head and macula in chronic Chagas disease by Cristiana L. M. Agra, Camila V. Ventura, Letícia D. da Fonte, Marcela R. V. Oliveira, Marília Leal, Maria Elisa L. S. M. Assunção, Maria da Glória A. M. Cavalcanti, Silvia M. M. Alves, Ana Karine Soares, Liana O. Ventura, Tiago S. Prata

“…No significant differences were observed among the studied variables. Although our findings suggested that the cardiovascular dysfunction resulting from chronic CD does not seem to cause significant structural or vascular preclinical changes to the ONH and the macula, the results herein benefit this patient population and may provide important preliminary information about the ocular impairment caused by the condition and its possible systemic complications.…”
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Establishment of a Breeding Approach Combined with Gamma Ray Irradiation and Tissue Regeneration for Highbush Blueberry by Xuan Yu, Haidi Yuan, Yihong Jin, Chuizheng Xia, Jiani Zhu, Jiali Che, Jiao Yang, Xiaofei Wang, Bingsong Zheng, Shufang Yang, Cristian Silvestri, Fuqiang Cui, Jianfang Zuo

“…Phenotypic variations, including changes in leaf color and growth characteristics, which may be due to altered plant response to environmental factors, were successfully observed in the first-generation (M1) plants. The height of M1 plants quantitatively decreased with increasing irradiation doses. …”
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Spatiotemporal characteristics of future precipitation variability in the Tianshan Mountain region of China by Xianglin Lyu, Junkai Du, Yaqin Qiu, Yangwen Jia, Chunfeng Hao, Hao Dong

“…New hydrological insights for the region: A negative correlation was observed between precipitation variability and precipitation, with areas experiencing high precipitation usually having low variability. …”
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First two mitochondrial genomes for the order Filobasidiales reveal novel gene rearrangements and intron dynamics of Tremellomycetes by Qiang Li, Zhijie Bao, Ke Tang, Huiyu Feng, Wenying Tu, Lijiao Li, Yunlei Han, Mei Cao, Changsong Zhao

“…Positive selection was observed in several protein-coding genes (PCGs) in the Agaricomycotina, Pucciniomycotina, and Ustilaginomycotina species, including cob, cox2, nad2, and rps3 genes. …”
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A normal electrocardiogram indicates a better prognosis in patients with moderate to very severe chronic obstructive pulmonary disease by Martina Kulirova, Miroslav Solar, Michal Kopecky, Barbora Novotna, Marek Plutinsky, Kristian Brat, Libor Fila, Petr Vanik, Pavlina Musilova, Tomas Dvorak, Petr Safranek, Michal Svoboda, Vladimir Koblizek

“…This multicenter noninterventional observational prospective study revealed a significant difference in 5-year overall survival between COPD patients with normal ECGs and those with prognostically significant or other ECG abnormalities (76.8%, 38.2%, and 63.4%, respectively; P < 0.001). …”
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Effect of Mouthwashes on Solubility and Sorption of Restorative Composites by José Pereira Leal, Jaqueline Damasceno da Silva, Rafaelle Fernanda Melão Leal, Carlos da Cunha Oliveira-Júnior, Vera Lúcia Gomes Prado, Glauber Campos Vale

“…Listerine Cool Mint (containing alcohol in its composition) caused the greatest degree of sorption for all composites tested in comparison to other rinses, while for solubility this behavior was observed for Opallis Flow and Durafill VS composite resins (p<0.05). …”
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One-Pot Template-Free Hydrothermal Synthesis of Monoclinic Hollow Microspheres and Their Enhanced Visible-Light Photocatalytic Activity by Bei Cheng, Wenguang Wang, Lei Shi, Jun Zhang, Jingrun Ran, Huogen Yu

“…A formation mechanism for the BiVO4 hollow spherical structure via a localized Ostwald ripening is proposed based on the experimental observations. In addition, studies of the photocatalytic properties by exposure to visible light irradiation demonstrate that the as-obtained BiVO4 hollow spheres show potential photocatalytic application. …”
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Validation Psychometrical analysis of Sexual Machism Scale (EMS-Sexism-12) among university students from Arequipa, Peru by Julio Cesar Huamani-Cahua, Estefany Cecilia Ojeda-Flores, Walter L Arias-Gallegos, Ferdinand Eddington Ceballos Bejarano, José Manuel Calizaya López

“…Furthermore, evidence of internal consistency reliability was observed for men and women, respectively (ω = .969; ω = .897). …”
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Endocrine and Metabolic Signaling in Retroperitoneal White Adipose Tissue Remodeling during Cold Acclimation by Aleksandra Jankovic, Aleksandra Korac, Biljana Buzadzic, Vesna Otasevic, Ana Stancic, Milica Vucetic, Milica Markelic, Ksenija Velickovic, Igor Golic, Bato Korac

“…What is more, after an initial decrease on day 1, a sequential increase in pyruvate dehydrogenase, acyl-CoA dehydrogenase, cytochrome c oxidase, and ATP synthase and a decrease in acetyl-CoA carboxylase (from day 3) were observed. Similar to adiponectin, protein level of resistin showed a biphasic profile: it increased after days 1, 3, and 7 and decreased below the control after 21 days of cold-acclimation. …”
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The Efficacy and Safety of Propiverine Hydrochloride in Patients with Overactive Bladder Symptoms Who Poorly Responded to Previous Anticholinergic Agents by Naoya Masumori, Shintaro Miyamoto, Taiji Tsukamoto, Seiji Furuya, Akihiko Iwasawa, Takashi Sato, Naoki Itoh, Akihiko Shibuya, Toshiro Oda

“…No increase in PVR was observed. The most frequent adverse event was dry mouth (13.7%), followed by constipation (6.8%). …”
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Initial Experience with Robotic Retropubic Urethropexy Compared to Open Retropubic Urethropexy by Pooja R. Patel, Mostafa A. Borahay, Audrey R. Puentes, Ana M. Rodriguez, Jessica Delaisse, Gokhan S. Kilic

“…A larger study is necessary to support our observations.…”
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Persistent Nasal Skin Lesions in Pemphigus Patients and the Role of Methotrexate in Treatment: A Case Series Study by Mohamad Reza Kavyani, Maryam Daneshpazhooh, Sama Heidari, Navid Namakizadeh Esfahani, Sarina Ahmadian, Arghavan Azizpour, Kamran Balighi

“…Following RTX therapy, significant improvements in the nasal lesions were observed after 11 (61.1%) sessions, with 8 patients (44.4%) achieving complete resolution within 6 months. …”
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Petroselinum crispum extract ameliorates scopolamine-induced cognitive dysfunction: role on apoptosis, inflammation and oxidative stress by Göksel Şener, Gözde Karakadıoglu, Dilek Ozbeyli, Seren Ede, Refiye Yanardag, Ozlem Sacan, Asli Aykac

“…Scopolamine-induced cognitive impairments observed in the NORT and MWMT, significantly improved with PC extract and galantamine treatments. …”
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Abnormal dynamic functional networks during pain-free periods: Resting-state co-activation pattern analysis in primary dysmenorrhea by Huiping Liu, Xing Su, Meiling Shang, Ling Ma, Weixian Bai, Hui Wang, Lu Quan, Youjun Li, Zigang Huang, Jiaxi He, Wanghuan Dun, Yuchen Zhang

“…Using the co-activation pattern (CAP) method, we investigated the dynamic network characteristics of brain functional networks and their relationship with pain-related emotions in a sample of 59 women with PDM and 57 demographically matched healthy controls (HCs) during the pain-free periovulation phase. We observed that patients with PDM showed significant alterations in brain dynamics compared to HCs in the slow-4 (0.027–0.073 Hz) frequency band during the pain-free periovulation phase. …”
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