High Prevalence of Human Papillomavirus in Colorectal Cancer in Hispanics: A Case-Control Study by Raul D. Bernabe-Dones, Maria Gonzalez-Pons, Alejandro Villar-Prados, Mercedes Lacourt-Ventura, Heriberto Rodríguez-Arroyo, Sharon Fonseca-Williams, Francisco E. Velazquez, Yaritza Diaz-Algorri, Sofia M. Lopez-Diaz, Nayra Rodríguez, Yasuhiro Yamamura, Marcia Cruz-Correa

“…HPV-16 was detected in 63.2% of the HPV-positive colorectal tumors; genome integration was observed in all HPV-16 positive cases. This is the first report showing the high prevalence of HPV infections in Caribbean Hispanic colorectal tumors. …”
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Plasticity-Related PKMζ Signaling in the Insular Cortex Is Involved in the Modulation of Neuropathic Pain after Nerve Injury by Jeongsoo Han, Minjee Kwon, Myeounghoon Cha, Motomasa Tanioka, Seong-Karp Hong, Sun Joon Bai, Bae Hwan Lee

“…After ζ-pseudosubstrate inhibitory peptide (ZIP, a selective inhibitor of PKMζ) injection, mechanical allodynia test and immunoblotting of PKMζ, phospho-PKMζ (p-PKMζ), and GluR1 and GluR2 were observed. IHC demonstrated that zif268 expression significantly increased in the IC after nerve injury. …”
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Psychosocial factors that predict happiness: A multigroup path analysis by Juan Martell-Muñoz, José Fernando Mora-Romo, David Luna, Filiberto Toledano-Toledano

“…Results: The hierarchical regression model obtained an explained variance of 57.4 %, while the structural model was 31.53 %. It was observed that a higher degree of gratitude predicted psychological well-being and happiness, while a higher optimism predicted a higher psychological well-being (β = 0.231, p = .001), mental health (β = 0.255, p = .001) and happiness (β = 0.518, p = .001). …”
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The Temporal Pattern of Arterial Stiffness during Aging: A Large-Scale Cross-Sectional Study by Zhengli Tang, Yuanyuan Lu, Yiming Hao, Robert Morris, Di Kang, Fang Wang, Lin Fan, Weijian Wang, Yiqin Wang, Feng Cheng

“…A gradual increase in baPWV with respect to age was observed, suggesting an increase in the stiffness of arterial vessels as age increases. …”
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Human Bone Marrow Contains Mesenchymal Stromal Stem Cells That Differentiate In Vitro into Contractile Myofibroblasts Controlling T Lymphocyte Proliferation by Yves Lecarpentier, Olivier Schussler, Antonija Sakic, José Maria Rincon-Garriz, Priscilla Soulie, Marie-Luce Bochaton-Piallat, Vincent Kindler

“…Moreover, MSC nested in collagen membranes were able to control T lymphocyte proliferation, and differentiated into adipocytes, chondrocytes, or osteoblasts. Our observations show that BM-derived MSC cultured in collagen membranes spontaneously differentiate into contractile myofibroblasts exhibiting unexpected properties in terms of cell differentiation potential and of immunomodulatory function.…”
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Factors Related to Complaints of Contact Dermatitis among Motorcycle Mechanics in The South And North Kembangan Areas, Jakarta in 2021 by Monica Sofia Maula, Mirta Dwi Rahmah Rusdy, Putri Handayani, Cut Alia Keumala Muda

“…The method of collecting data from the source of information used is in the form of primary data using measuring instruments in the form of questionnaires and observation sheets. Result: The proportion of workers who complained of work-related contact dermatitis were 13 workshop workers (37.1%). …”
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Effects of Upstream Component and Air Injection on Water Droplet Impingement Characteristics for Downstream Surfaces by Xiaobin Shen, Yundan Tan, Rendong Yu, Xiaochuan Liu, Guiping Lin, Zhiqiang Xu, Yuandong Guo

“…The droplet deflections and trajectory crossings are observed clearly under the influence of the upstream component, and the Lagrangian results of downstream surfaces differ from those of the Eulerian method. …”
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Comparison of Medpor Coated Tear Drainage Tube versus Silicon Tear Drainage Tube in Conjunctivodacryocystorhinostomy: Problems and Solutions by Selam Yekta Sendul, Halil Huseyin Cagatay, Burcu Dirim, Mehmet Demir, Ali Atakhan Yıldız, Zeynep Acar, Sonmez Cinar, Dilek Guven

“…In our study, the most significant complication we observed in the use of silicon tear drainage tubes was tube extrusion,whereas the leading complication related to the use of Medpor coated tear drainage tubes was tube obstruction.…”
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Impact of Preoperative Three-Dimensional Computed Tomography Cholangiography on Postoperative Resection Margin Status in Patients Operated due to Hilar Cholangiocarcinoma by A. Andert, P. Bruners, C. Heidenhain, F. Ulmer, C. D. Klink, P. H. Alizai, C. Kuhl, U. P. Neumann, M. Binnebösel

“…Curative liver resection with R0 status was reached in 88% of patients in group ERC and 87% of patients in group 3D-ERC (p=1.00). We could not observe any differences with regard to postoperative complications, hospital stay, and mortality rate between both groups. …”
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Intraperitoneal fipronil effects on liver histopathological, biochemistry and morphology in Caspian kutum, Rutilus frisii kutum (Kamenskii, 1901) by R. Alijani Ardeshir, H. Zolgharnein, A.A. Movahedinia, N. Salamat, E. Zabihi, J. Regenstein

“…This dependence was also observed for HSI and the liver biochemical test (alanine and aspartate transaminase). …”
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Histopathological analysis of the liver in hypercholesterolemia rats treated with Dillenia serrata fruits by Tien, Tri Wistya Utami, Pranita Aritrina, Laode Kardin, Sukurni, Andi Noor Kholidha Syarifin

“…Rat liver tissues were analyzed histologically using Hematoxylin-Eosin (HE) staining, and were observed under a light microscope at 40x magnification in five wide fields of view. …”
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First-in-human exploratory trial assessing safety, feasibility, and efficacy of artificial protein (silk-elastin) in promoting healing in patients with meniscus injuries by Masakazu Ishikawa, Shunya Tsuji, Goki Kamei, Kyohei Nakata, Akinori Nekomoto, Naofumi Hashiguchi, Tomoyuki Nakasa, Atsuo Nakamae, Naosuke Kamei, Keiichiro Inoue, Shingo Kawabata, Keiko Ueda, Nobuo Adachi

“…Significant improvements were observed in Lysholm and visual analog scale scores (P < 0.05), with the knee injury and osteoarthritis outcome scores showing significant improvement in the symptom subscale. …”
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Experimental Investigation into the Bedding Plane Slip Effect on the Overlying Strata Behavior in Longwall Top Coal Caving of Soft Coal Seam by Hengfeng Liu, Jixiong Zhang, Nan Zhou, Qiang Sun, Meng Li, Zhizhong Cui

“…The bedding plane slip becomes steady after gradual increase and leads to the subsidence of the overlying strata in the “three-soft” coal seam. The observed initial caving interval of the main roof by field measurement is 51 m, which is consistent with the results of physical similarity simulation experiments and theoretical analysis. …”
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Enhanced Neuroprotective Effects of Coadministration of Tetrandrine with Glutathione in Preclinical Model of Parkinson’s Disease by Xiang-Yun Li, Guang-Hai Mei, Qiang Dong, Yu Zhang, Zhuang-Li Guo, Jing-Jing Su, Yu-Ping Tang, Xue-Hong Jin, Hou-Guang Zhou, Yan-Yan Huang

“…However, in the GSH + Tet group, we observed markedly decreased oxidative damage, inhibition of DA metabolism and enhanced DA synthesis, increased tyrosine hydroxylase- (TH-) immunopositive neuronal survival, and delayed apoptosis of dopaminergic neurons in the SN. …”
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Plant growth-promoting bacteria and nanomaterials synergism to enhance Lolium perenne growth and phytoremediation in cadmium-contaminated soil by Asifa Farooqi, Ejaz ul Haq, Anders Johansen, Lea Ellegaard-Jensen, Mazhar Iqbal, Sohail Yousaf, Maximilian Lackner

“…The highest Cd uptake (92 %) by ryegrass was observed in Serratia bozhouensis and GNPs treatments. …”
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Phase-transition-induced Collapse of Proto-compact Stars and Its Implication for Supernova Explosions by Xu-Run Huang, Shuai Zha, Ming-chung Chu, Evan P. O’Connor, Lie-Wen Chen

“…Our findings can guide further self-consistent investigations on PT-driven core-collapse supernovae and help identify hadron−quark PT-induced PCS collapse from future observations.…”
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Moments that matter: childhood pain treatment shapes pain for life—we can do better every time in every child by Rebeccah Slater, Suellen Walker, Christopher Eccleston, Carlo Bellieni, Tanvi Hirekodi, Ricardo Carbajal, Lucinda Smart, William Laughey, Maria M. Cobo, Stefan Friedrichsdorf

“…We argue that better informed and motivated healthcare professionals and families can advocate for appropriate pain relief in every child, every time. Observations Engaging communication campaigns are needed to educate our healthcare professionals. …”
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Preparation of hyperbranched 4-dimethylaminopyridine catalyst for the efficient synthesis of vitamin E succinate by Li, Haining, Zhang, Tiantian, Tang, Kai, Li, Binglin, Zhang, Xiaoli, Zhao, Binxia, Wang, Jiao

“…The highest catalytic activity was observed in the hyperbranched catalyst, which reached 24.97 mmol/h${\cdot }$g. …”
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Effect of Preadolescents&#x2019; Obesity on Inhibitory Control During Stop-Signal Task: A Functional EEG Network Study by Yuqin Li, Qian Yang, Yuxin Liu, Yutong Zheng, Jianfu Li, Chunli Chen, Baodan Chen, Dezhong Yao, Liang Yu, Peng Xu, Fali Li, Yi Liang

“…Given the huge conflict-monitoring and inhibitory control demands of the task, both enhanced network connectivity and properties were observed under the &#x201C;No-go&#x201D; compared to the &#x201C;Go&#x201D; condition for both obese and non-obese preadolescents. …”
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PEPITEM, its tripeptide pharmacophores and their peptidomimetic analogues regulate the inflammatory response through parenteral and topical dosing in models of peritonitis and psor... by Anella Saviano, Bonita Apta, Samantha Tull, Laleh Pezhman, Areeba Fatima, Mustafa Sevim, Antonio Mete, Myriam Chimen, Anna Schettino, Noemi Marigliano, Helen M. McGettrick, Asif J. Iqbal, Francesco Maione, G. Ed Rainger

“…The order of magnitude increase in efficacy observed for some peptidomimetics may deliver agents with enhanced pharmacological characteristics compared to the parent PEPITEM sequence. …”
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